A calm body of water, a sandy beach, and a forested area in the distance.

Cape Girardeau Vacation Rentals

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Check prices for these dates

In two weeks
Jul 24 - Jul 26
In two months
Sep 4 - Sep 6
In three months
Oct 2 - Oct 4
In four months
Oct 30 - Nov 1

Our top choices for Cape Girardeau vacation rentals

Living area

Little Blue Cottage on Spanish

Little Blue Cottage on Spanish
Cape Girardeau
8.4 out of 10, Very good, (57 reviews)
"Great cute place. "
United States
Jeremy W.
The price is CA $115
CA $153 total
includes taxes & fees
Jul 14 - Jul 15
Little Blue Cottage on Spanish
Outdoor dining

Studio Apt | King Bed, Full Kitchen · By KeenStays

Studio Apt | King Bed, Full Kitchen · By KeenStays
Cape Girardeau
10.0 out of 10, Exceptional, (1 review)
"I loved the location and the staff was wonderful. The bed was comfortable. I loved that King size bed!"
United States
Melvin
The price is CA $113
CA $237 total
includes taxes & fees
Jul 23 - Jul 24
Studio Apt | King Bed, Full Kitchen · By KeenStays
Interior

Charming Secluded Getaway Cabin within minutes of amenities

Charming Secluded Getaway Cabin within minutes of amenities
Cape girardeau
10.0 out of 10, Exceptional, (22 reviews)
"Very peaceful"
United States
Gloria M.
The price is CA $220
CA $434 total
includes taxes & fees
Jul 13 - Jul 14
Charming Secluded Getaway Cabin within minutes of amenities
Property grounds

European Inspired Lofted Cottage in Tiny Home Village

European Inspired Lofted Cottage in Tiny Home Village
Cape Girardeau
The price is CA $220
CA $320 total
includes taxes & fees
Jul 11 - Jul 12
European Inspired Lofted Cottage in Tiny Home Village
Property grounds

Vibrant Lofted Tiny Home

Vibrant Lofted Tiny Home
Cape Girardeau
10.0 out of 10, Exceptional, (1 review)
"The tiny house was adorable, clean, and everything we expected. We can’t wait to stay in the others. We definitely recommend staying here. Lisa and Holly have done a wonderful job. Holly was great at getting back to me. Loved everything about our stay and the trip. Thank you so much"
United States
Kim K.
The price is CA $228
CA $332 total
includes taxes & fees
Jul 23 - Jul 24
Vibrant Lofted Tiny Home
1 bedroom, desk, iron/ironing board, WiFi

The Cottage, Rusted Route Farms

The Cottage, Rusted Route Farms
Jackson
10.0 out of 10, Exceptional, (2 reviews)
"This Cottage was very nice and clean and well maintained. The meat tray that we ordered and the breakfast tray was beyond Fabulous!!! My husband is still talking about it. . .Rick & Renee Christman"
United States
Renee C.
The price is CA $177
CA $282 total
includes taxes & fees
Jul 13 - Jul 14
The Cottage, Rusted Route Farms
Interior

The Twisted Sassafras Treehouse

The Twisted Sassafras Treehouse
Cape Girardeau
10.0 out of 10, Exceptional, (34 reviews)
"Nice, quiet, close to shopping & restaurants"
United States
Jaime M.
The price is CA $339
CA $492 total
includes taxes & fees
Jul 27 - Jul 28
The Twisted Sassafras Treehouse
Exterior

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool

3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Cape Girardeau
8.8 out of 10, Excellent, (41 reviews)
"Will definitely book again! Great location, comfortable stay."
United States
Pynktoria !.
The price is CA $254
CA $449 total
includes taxes & fees
Jul 23 - Jul 24
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
TV, fireplace

Gorgeous 1856 Log Cabin, Completely Renovated

Gorgeous 1856 Log Cabin, Completely Renovated
Jackson
10.0 out of 10, Exceptional, (4 reviews)
"This was the coolest place! Our family absolutely loved it. Plenty of space, bathrooms, sitting areas outside were plenty as well as fireplaces and fire pit. The bedrooms are spacious- the area where the two twin beds are is downstairs and the beds are smaller but just know that going in. Beautiful area. We’d love to stay again."
United States
Victoria
The price is CA $283
CA $446 total
includes taxes & fees
Jul 13 - Jul 14
Gorgeous 1856 Log Cabin, Completely Renovated
Terrace/patio

Romantic Tea Cottage Retreat on Boulder Creek with Firepit and Deck

Romantic Tea Cottage Retreat on Boulder Creek with Firepit and Deck
Cape Girardeau
The price is CA $220
CA $322 total
includes taxes & fees
Jul 23 - Jul 24
Romantic Tea Cottage Retreat on Boulder Creek with Firepit and Deck
Fridge, microwave, oven, stovetop

Modern Boho Getaway 1BR Apartment By KeenStays

Modern Boho Getaway 1BR Apartment By KeenStays
Cape Girardeau
The price is CA $113
CA $237 total
includes taxes & fees
Aug 2 - Aug 3
Modern Boho Getaway 1BR Apartment By KeenStays
1 bedroom, free WiFi, bed sheets

Purple Tiny House with Fire pit & Nature

Purple Tiny House with Fire pit & Nature
Cape Girardeau
The price is CA $196
CA $292 total
includes taxes & fees
Jul 16 - Jul 17
Purple Tiny House with Fire pit & Nature
Pool

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More

4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Cape Girardeau
9.6 out of 10, Exceptional, (9 reviews)
"Nice place, great times"
United States
Jace W.
The price is CA $478
CA $786 total
includes taxes & fees
Jul 23 - Jul 24
4-Bedroom Home - 2 King Beds, Summer Pool, Pool Table, Air Hockey + More
Outdoor dining

A-Frame Cottage with Deck in Charming Inspiration Village

A-Frame Cottage with Deck in Charming Inspiration Village
Cape Girardeau
The price is CA $236
CA $343 total
includes taxes & fees
Jul 13 - Jul 14
A-Frame Cottage with Deck in Charming Inspiration Village
TV, offices

Fresh & Cozy Retreat w/ King Bed · By KeenStays

Fresh & Cozy Retreat w/ King Bed · By KeenStays
Cape Girardeau
The price is CA $113
CA $237 total
includes taxes & fees
Aug 9 - Aug 10
Fresh & Cozy Retreat w/ King Bed · By KeenStays
Smart TV

Rent All 5 Suites at Peach Tree Inn

Rent All 5 Suites at Peach Tree Inn
Cobden
The price is CA $906
CA $1,112 total
includes taxes & fees
Jul 14 - Jul 15
Rent All 5 Suites at Peach Tree Inn
Exterior

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (422 reviews)
"Great location. Cozy cabin. Would stay there again. "
United States
jeffrey s
The price is CA $166
CA $284 total
includes taxes & fees
Jul 16 - Jul 17
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Property grounds

Charming cottage overlooking Lake Acre

Charming cottage overlooking Lake Acre
Dongola
10.0 out of 10, Exceptional, (105 reviews)
"Enjoyed our stay great hospitality, everything we needed was addressed. We would highly recommend staying there. Great location "
United States
carlton h.
The price is CA $191
CA $402 total
includes taxes & fees
Jul 21 - Jul 22
Charming cottage overlooking Lake Acre
Exterior detail

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!

3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Makanda
9.8 out of 10, Exceptional, (67 reviews)
"Nice cabin. Location is great, near many wineries. Host was super friendly. We had no issues arise."
United States
James S.
The price is CA $133
CA $256 total
includes taxes & fees
Aug 3 - Aug 4
3 Minutes to Giant City - 6 Minutes to SIU - 4 Minutes to Shawnee Winetrail!
Terrace/patio

Contemporary Glamping with Native American Appeal

Contemporary Glamping with Native American Appeal
Anna
9.8 out of 10, Exceptional, (160 reviews)
"Everything was just as advertised. Perfect stay. "
United States
Jonathan P.
The price is CA $250
CA $463 total
includes taxes & fees
Jul 13 - Jul 14
Contemporary Glamping with Native American Appeal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cape Girardeau Hotel Reviews

Pear Tree Inn Cape Girardeau West

Pear Tree Inn Cape Girardeau West

10/10 Excellent
"Rooms were very clean. Staff was excellent and informative. Parking by side entrance was excellent."
Linda 1-night trip
Posted 1 hour ago
Pear Tree Inn Cape Girardeau West

Find out more about Cape Girardeau

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Cape Girardeau. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Explore a world of travel with Expedia

Frequently asked questions

Can I find vacation rentals in Cape Girardeau?

Yes, we offer vacation rentals in Cape Girardeau near Cape Splash Family Aquatic Center, or you can select a more remote option if you're looking for extra privacy while you relax. Visitors like the top-notch restaurants and shops in Cape Girardeau. Make sure you allow time to enjoy the riverfront during your vacation.

What are some of the best vacation home rentals in Cape Girardeau?

Serenity South -- Gardens, River-Views, and Refreshing Space: This Cape Girardeau vacation home rental is located on a river and has a fireplace, a balcony, and air-conditioning to put you at ease in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Some other homes for rent in Cape Girardeau include “Brickyard”-Recently Remodeled Dutch Colonial Revival in Downtown Cape Girardeau and Little Blue Cottage on Spanish.

How many vacation rentals will I find in Cape Girardeau?

Choose from 25 Expedia vacation rentals in Cape Girardeau for a memorable vacation.

What can I see and do in Cape Girardeau?

Family-friendly attractions include Cape Splash Family Aquatic Center and Cape Girardeau Conservation Nature Center, whereas Shawnee National Forest and Mississippi River are a couple of great spots to enjoy the outdoors. While here, eDen Spa & Salon and Century Casino & Hotel Cape Girardeau are other places worth a visit.

What are vacation rentals like in Cape Girardeau?

Vacation rentals are private properties you can book for a couple days or more in Cape Girardeau. Vacation rentals offer amenities such as hot tubs, fire pits, and patios so your stay will be comfortable. If you're concerned about cleanliness, vacation rentals can offer a sense of privacy away from public hotel elevators and lobbies bustling with people while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.