Title: Book the Best BUSINESS Hotels in Big Pine Key in 2026 | Expedia.ca [Big Pine Key Travel Guide](https://expedia.ca/Big-Pine-Key.dx7195)[Hotels in Big Pine Key](https://expedia.ca/Big-Pine-Key-Hotels.d7195.Travel-Guide-Hotels)[Vacation Rentals in Big Pine Key](https://expedia.ca/Big-Pine-Key-Vacation-Rentals.d7195.Travel-Guide-VacationRentals)[Flights to Big Pine Key](https://expedia.ca/Cheap-Flights-To-Big-Pine-Key.d7195.Travel-Guide-Flights)[Things to do in Big Pine Key](https://expedia.ca/Things-To-Do-In-Big-Pine-Key.d7195.Travel-Guide-Activities)[Big Pine Key Car Rentals](https://expedia.ca/Car-Rentals-In-Big-Pine-Key.d7195.Car-Rental-Guide)[Big Pine Key Vacation Packages](https://expedia.ca/Big-Pine-Key.d7195.Destination-Travel-Guides) ![Bahia Honda State Park showing general coastal views, a bridge and a beach](https://images.trvl-media.com/place/7195/5947ed8f-07bf-40de-9b8f-70a7b9a8077a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/7195/5947ed8f-07bf-40de-9b8f-70a7b9a8077a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Big Pine Key Business Hotels Tonight [Jan 17 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=7195&startDate=2026-01-17&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Jan 18 - Jan 19](https://www.expedia.ca/Hotel-Search?regionId=7195&startDate=2026-01-18&endDate=2026-01-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=7195&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) In two weeks [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=7195&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Big Pine Key business-friendly hotels ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/19900/19823/b7875c57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 King Bed with Sofa bed, Balcony, Bay View](https://images.trvl-media.com/lodging/1000000/20000/19900/19823/7bef632e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Balcony, Bay View](https://images.trvl-media.com/lodging/1000000/20000/19900/19823/504a40b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/19900/19823/d84b43ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Marathon Florida Keys [](https://www.expedia.ca/Marathon-Hotels-Fairfield-Inn-Suites-By-Marriott-Marathon-Florida-Keys.h19823.Hotel-Information) Marathon 9.2/10 Wonderful (1,070 reviews) "Great hotel, will stay there again. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Mark CA $332 CA $373 total includes taxes & fees Jan 28 - Jan 29 [](https://www.expedia.ca/Marathon-Hotels-Fairfield-Inn-Suites-By-Marriott-Marathon-Florida-Keys.h19823.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2180000/2172800/2172798/a88151b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Suite, 3 Bedrooms, 2 Bathrooms | Property grounds](https://images.trvl-media.com/lodging/3000000/2180000/2172800/2172798/c97287f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Television](https://images.trvl-media.com/lodging/3000000/2180000/2172800/2172798/4eceb060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Large Efficiency | Private kitchenette](https://images.trvl-media.com/lodging/3000000/2180000/2172800/2172798/e8d6ee2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Siesta Motel [](https://www.expedia.ca/Marathon-Hotels-Siesta-Motel.h2172798.Hotel-Information) Marathon 7.4/10 Good (705 reviews) "Although needing some interior updates, the room was clean and comfortable and the owners and staff was very friendly. We would stay here again in the future." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) stan CA $180 CA $203 total includes taxes & fees Jan 27 - Jan 28 [](https://www.expedia.ca/Marathon-Hotels-Siesta-Motel.h2172798.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/430000/428800/428789/27d5f1e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/430000/428800/428789/7e7da461.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/430000/428800/428789/1b910ab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/428800/428789/w3840h2556x0y0-04b24ad8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Marathon - Florida Keys [](https://www.expedia.ca/Marathon-Hotels-Hampton-Inn-Marathon-Florida-Keys.h428789.Hotel-Information) Marathon 9.0/10 Wonderful (1,001 reviews) "Good room and breakfast " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Harshad CA $310 CA $348 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Marathon-Hotels-Hampton-Inn-Marathon-Florida-Keys.h428789.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/899000/898967/0e73156e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/1000000/900000/899000/898967/b411569e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/900000/899000/898967/c67eb530.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Regional cuisine](https://images.trvl-media.com/lodging/1000000/900000/899000/898967/4e74ed3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Skipjack Resort & Marina [](https://www.expedia.ca/Marathon-Hotels-Skipjack-Resort-Marina.h898967.Hotel-Information) Marathon 8.6/10 Excellent (1,219 reviews) "Beautiful location clean rooms friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tiffany CA $335 CA $434 total includes taxes & fees Jan 20 - Jan 21 [](https://www.expedia.ca/Marathon-Hotels-Skipjack-Resort-Marina.h898967.Hotel-Information) ![On the beach, beach cabanas, sun loungers](https://images.trvl-media.com/lodging/11000000/10560000/10554600/10554536/30a374ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/11000000/10560000/10554600/10554536/b0c6ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Banquet hall](https://images.trvl-media.com/lodging/11000000/10560000/10554600/10554536/246f3120.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/11000000/10560000/10554600/10554536/acafccbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys [](https://www.expedia.ca/Marathon-Hotels-Courtyard-By-Marriott-Marathon-Florida-Keys.h10554536.Hotel-Information) Marathon 9.0/10 Wonderful (1,000 reviews) "Breakfast was great! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Huiting CA $389 CA $493 total includes taxes & fees Jan 25 - Jan 26 [](https://www.expedia.ca/Marathon-Hotels-Courtyard-By-Marriott-Marathon-Florida-Keys.h10554536.Hotel-Information) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/2000000/1170000/1169600/1169583/0e78e180.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Steam room, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/2000000/1170000/1169600/1169583/13c72c1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1170000/1169600/1169583/cb981197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1170000/1169600/1169583/71d566a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton [](https://www.expedia.ca/Marathon-Hotels-Faro-Blanco-Resort-Yacht-Club.h1169583.Hotel-Information) Marathon 8.8/10 Excellent (1,249 reviews) "Room was spotless, staff was so sweet and helpful when we had questions. Would stay here again !" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Theresa CA $398 CA $499 total includes taxes & fees Jan 26 - Jan 27 [](https://www.expedia.ca/Marathon-Hotels-Faro-Blanco-Resort-Yacht-Club.h1169583.Hotel-Information) ![On the beach, sun loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/f6566b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/5a054f37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/9f64224f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/04484d29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Isla Bella Beach Resort & Spa [](https://www.expedia.ca/Marathon-Hotels-Isla-Bella-Beach-Resort-Spa.h24101706.Hotel-Information) Marathon 9.2/10 Wonderful (1,079 reviews) "Great place! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Christine CA $574 CA $738 total includes taxes & fees Jan 19 - Jan 20 [](https://www.expedia.ca/Marathon-Hotels-Isla-Bella-Beach-Resort-Spa.h24101706.Hotel-Information) ![3 outdoor pools, sun loungers](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/854776a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Villa, 3 Bedrooms, Beachfront](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/f82dd976.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/9ad49064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/c4d130ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tranquility Bay Beachfront Hotel and Resort [](https://www.expedia.ca/Marathon-Hotels-Tranquility-Bay-Beachfront-Hotel-And-Resort.h117099.Hotel-Information) Marathon 8.8/10 Excellent (1,002 reviews) "Yes, the room was very clean. We especially enjoyed the heated small pool close to our room. The grounds were beautiful and very well maintained. We enjoyed the chairs by the water. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Hal CA $499 CA $653 total includes taxes & fees Jan 20 - Jan 21 [](https://www.expedia.ca/Marathon-Hotels-Tranquility-Bay-Beachfront-Hotel-And-Resort.h117099.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-31&endDate=2026-02-01®ionId=7195&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Big Pine Key Hotel Reviews ![Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton](https://images.trvl-media.com/lodging/2000000/1170000/1169600/1169583/16bbce87_y.jpg) ### Faro Blanco Resort & Yacht Club Marathon, Curio by Hilton 10/10 Excellent "Beautiful room. Very friendly staff. " [](https://expedia.ca/Marathon-Hotels-Faro-Blanco-Resort-Yacht-Club.h1169583.Hotel-Information) ![Fairfield Inn & Suites by Marriott Marathon Florida Keys](https://images.trvl-media.com/lodging/1000000/20000/19900/19823/d21c9344_y.jpg) ### Fairfield Inn & Suites by Marriott Marathon Florida Keys 10/10 Excellent "Clean room, friendly staff, hotel had pool with hammocks which was relaxing. They also had free breakfast. The gym was also very nice. Marathon was a nice city to visit. I would stay here again in the future." [](https://expedia.ca/Marathon-Hotels-Fairfield-Inn-Suites-By-Marriott-Marathon-Florida-Keys.h19823.Hotel-Information) ![Glunz Ocean Beach Hotel & Resort](https://images.trvl-media.com/lodging/3000000/2870000/2869800/2869762/d71b6752_y.jpg) ### Glunz Ocean Beach Hotel & Resort 10/10 Excellent "The staff were very friendly and responsive. The workout room was nice with machines, dumbbells, and TRX suspension straps. The restaurant next door was great with live nightly music. Hope to return in the future. " [](https://expedia.ca/Key-Colony-Beach-Hotels-Glunz-Ocean-Beach-Hotel-Resort.h2869762.Hotel-Information) ![Kingsail Resort](https://images.trvl-media.com/lodging/2000000/1780000/1775600/1775568/96bf2fd2_y.jpg) ### Kingsail Resort 10/10 Excellent "Great staff nice property. " [](https://expedia.ca/Marathon-Hotels-Kingsail-Resort.h1775568.Hotel-Information) ![Looe Key Reef Resort](https://images.trvl-media.com/lodging/5000000/4760000/4759500/4759500/63d12f01_y.jpg) ### Looe Key Reef Resort 10/10 Excellent "I love how friendly this hotel is. I highly recommend the second floor with the double beds because they are the most comfortable and can have a awesome view of the canal in the back. The rooms are always super clean and have different access of cooling." [](https://expedia.ca/Ramrod-Key-Hotels-Looe-Key-Reef-Resort.h4759500.Hotel-Information) ![Tranquility Bay Beachfront Hotel and Resort](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/2efaf74f_y.jpg) ### Tranquility Bay Beachfront Hotel and Resort 10/10 Excellent "Yes, the room was very clean. We especially enjoyed the heated small pool close to our room. The grounds were beautiful and very well maintained. We enjoyed the chairs by the water. " [](https://expedia.ca/Marathon-Hotels-Tranquility-Bay-Beachfront-Hotel-And-Resort.h117099.Hotel-Information) ![Captain Pips Marina & Hideaway](https://images.trvl-media.com/lodging/5000000/4740000/4734200/4734183/8ef9dce3_y.jpg) ### Captain Pips Marina & Hideaway 10/10 Excellent "Receptionists friendliness and professionalism" [](https://expedia.ca/Marathon-Hotels-Captain-Pips-Marina-Hideaway.h4734183.Hotel-Information) ![Coconut Cay Resort & Marina](https://images.trvl-media.com/lodging/2000000/1190000/1181000/1180935/9fe9bbb4_y.jpg) ### Coconut Cay Resort & Marina 10/10 Excellent "The location is great, there are tons of restaurants and amenities like paddle boards, kayaks, and a pool. The staff were all very friendly and helpful. The rooms were very clean and comfortable. " [](https://expedia.ca/Marathon-Hotels-Coconut-Cay-Resort-Marina.h1180935.Hotel-Information) ![Parmer's Resort](https://images.trvl-media.com/lodging/6000000/5570000/5561500/5561465/6492712a_y.jpg) ### Parmer's Resort 10/10 Excellent "Excellent" [](https://expedia.ca/Little-Torch-Key-Hotels-Parmers-Resort.h5561465.Hotel-Information) ## Frequently asked questions ### Why book your business-friendly hotel in Big Pine Key with Expedia? ### How can I find cheap business-friendly hotels in Big Pine Key? ## Explore a world of travel with Expedia - Lodging - More ways to book - [All Inclusive Resorts and in Atlantis Estates ](https://www.expedia.ca/Atlantis-Estates-Big-Pine-Key-Hotels-All-Inclusive-Hotel.0-n553248635976480034-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Atlantis Estates ](https://www.expedia.ca/Atlantis-Estates-Big-Pine-Key-Hotels-Cheap-Hotels.0-n553248635976480034-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in Atlantis Estates ](https://www.expedia.ca/Atlantis-Estates-Big-Pine-Key-Hotels-Hotels-With-Free-Airport-Shuttle.0-n553248635976480034-0-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - 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