Title: Book the Best BUSINESS Hotels in Big Pine Key in 2026 | Expedia.ca [Big Pine Key Travel Guide](https://expedia.ca/Big-Pine-Key.dx7195)[Hotels in Big Pine Key](https://expedia.ca/Big-Pine-Key-Hotels.d7195.Travel-Guide-Hotels)[Vacation Rentals in Big Pine Key](https://expedia.ca/Big-Pine-Key-Vacation-Rentals.d7195.Travel-Guide-VacationRentals)[Flights to Big Pine Key](https://expedia.ca/Cheap-Flights-To-Big-Pine-Key.d7195.Travel-Guide-Flights)[Things to do in Big Pine Key](https://expedia.ca/Things-To-Do-In-Big-Pine-Key.d7195.Travel-Guide-Activities)[Big Pine Key Car Rentals](https://expedia.ca/Car-Rentals-In-Big-Pine-Key.d7195.Car-Rental-Guide)[Big Pine Key Vacation Packages](https://expedia.ca/Big-Pine-Key.d7195.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/7195/5947ed8f-07bf-40de-9b8f-70a7b9a8077a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/7195/5947ed8f-07bf-40de-9b8f-70a7b9a8077a.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Big Pine Key Business Hotels Tonight [Apr 8 - Apr 9](https://www.expedia.ca/Hotel-Search?regionId=7195&startDate=2026-04-08&endDate=2026-04-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Apr 9 - Apr 10](https://www.expedia.ca/Hotel-Search?regionId=7195&startDate=2026-04-09&endDate=2026-04-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Apr 10 - Apr 12](https://www.expedia.ca/Hotel-Search?regionId=7195&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=7195&startDate=2026-04-17&endDate=2026-04-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Big Pine Key business-friendly hotels ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/20000/19900/19823/b7875c57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/19900/19823/d84b43ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/20000/19900/19823/061698ac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Bay View](https://images.trvl-media.com/lodging/1000000/20000/19900/19823/504a40b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Marathon Florida Keys [](https://www.expedia.ca/Marathon-Hotels-Fairfield-Inn-Suites-By-Marriott-Marathon-Florida-Keys.h19823.Hotel-Information) Marathon 9.2/10 Wonderful (1,107 reviews) "Great restaurant attached to the hotel. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jenny CA $304 CA $341 total includes taxes & fees May 3 - May 4 [](https://www.expedia.ca/Marathon-Hotels-Fairfield-Inn-Suites-By-Marriott-Marathon-Florida-Keys.h19823.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/3000000/2180000/2172800/2172798/a88151b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Large Efficiency](https://images.trvl-media.com/lodging/3000000/2180000/2172800/2172798/89cba422.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Television](https://images.trvl-media.com/lodging/3000000/2180000/2172800/2172798/4eceb060.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Large Efficiency | Private kitchenette](https://images.trvl-media.com/lodging/3000000/2180000/2172800/2172798/e8d6ee2d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Siesta Motel [](https://www.expedia.ca/Marathon-Hotels-Siesta-Motel.h2172798.Hotel-Information) Marathon 7.4/10 Good (741 reviews) "Older facility, very clean, surprisingly quiet, comfortable and cute! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $200 CA $225 total includes taxes & fees Apr 15 - Apr 16 [](https://www.expedia.ca/Marathon-Hotels-Siesta-Motel.h2172798.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/430000/428800/428789/27d5f1e5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/1000000/430000/428800/428789/3b51f998.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/430000/428800/428789/1b910ab7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/430000/428800/428789/w3840h2556x0y0-04b24ad8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Marathon - Florida Keys [](https://www.expedia.ca/Marathon-Hotels-Hampton-Inn-Marathon-Florida-Keys.h428789.Hotel-Information) Marathon 9.0/10 Wonderful (1,003 reviews) "We liked the hotel overall, and the breakfast was fresh every morning " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) April CA $260 CA $293 total includes taxes & fees May 4 - May 5 [](https://www.expedia.ca/Marathon-Hotels-Hampton-Inn-Marathon-Florida-Keys.h428789.Hotel-Information) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/2000000/1170000/1169600/1169583/7ec74e61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/2000000/1170000/1169600/1169583/69dd42b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1170000/1169600/1169583/15d342f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch, dinner served; Caribbean cuisine](https://images.trvl-media.com/lodging/2000000/1170000/1169600/1169583/w4495h3000x5y0-bf477add.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Faro Blanco Resort Marathon Florida Keys, Curio by Hilton [](https://www.expedia.ca/Marathon-Hotels-Faro-Blanco-Resort-Yacht-Club.h1169583.Hotel-Information) Marathon 8.8/10 Excellent (1,179 reviews) "Beautiful hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brooke CA $302 CA $392 total includes taxes & fees May 3 - May 4 [](https://www.expedia.ca/Marathon-Hotels-Faro-Blanco-Resort-Yacht-Club.h1169583.Hotel-Information) ![On the beach, beach cabanas, sun loungers](https://images.trvl-media.com/lodging/11000000/10560000/10554600/10554536/30a374ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools, cabanas (surcharge), pool umbrellas](https://images.trvl-media.com/lodging/11000000/10560000/10554600/10554536/5f4107d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/11000000/10560000/10554600/10554536/b0c6ffbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 bars/lounges, poolside bar](https://images.trvl-media.com/lodging/11000000/10560000/10554600/10554536/acafccbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys [](https://www.expedia.ca/Marathon-Hotels-Courtyard-By-Marriott-Marathon-Florida-Keys.h10554536.Hotel-Information) Marathon 9.0/10 Wonderful (1,001 reviews) "beautiful property - clean, friendly staff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) laurie CA $309 CA $402 total includes taxes & fees May 7 - May 8 [](https://www.expedia.ca/Marathon-Hotels-Courtyard-By-Marriott-Marathon-Florida-Keys.h10554536.Hotel-Information) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/900000/899000/898967/0e73156e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Marina](https://images.trvl-media.com/lodging/1000000/900000/899000/898967/7e708788.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/900000/899000/898967/c67eb530.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Regional cuisine](https://images.trvl-media.com/lodging/1000000/900000/899000/898967/4e74ed3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Skipjack Resort & Marina [](https://www.expedia.ca/Marathon-Hotels-Skipjack-Resort-Marina.h898967.Hotel-Information) Marathon 8.6/10 Excellent (1,246 reviews) "The pool was ok. It was crowded for most of our stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teresa CA $268 CA $358 total includes taxes & fees May 4 - May 5 [](https://www.expedia.ca/Marathon-Hotels-Skipjack-Resort-Marina.h898967.Hotel-Information) ![3 outdoor pools, sun loungers](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/854776a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/c4d130ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/92bf29ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from room](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/9ad49064.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tranquility Bay Beachfront Hotel and Resort [](https://www.expedia.ca/Marathon-Hotels-Tranquility-Bay-Beachfront-Hotel-And-Resort.h117099.Hotel-Information) Marathon 8.8/10 Excellent (1,000 reviews) "Amazing resort " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joy CA $390 CA $529 total includes taxes & fees May 3 - May 4 [](https://www.expedia.ca/Marathon-Hotels-Tranquility-Bay-Beachfront-Hotel-And-Resort.h117099.Hotel-Information) ![On the beach, sun loungers, beach umbrellas, beach towels](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/f6566b0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast and dinner served](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/02a3a50c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/04484d29.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![5 outdoor pools, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/25000000/24110000/24101800/24101706/5a054f37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Isla Bella Beach Resort & Spa [](https://www.expedia.ca/Marathon-Hotels-Isla-Bella-Beach-Resort-Spa.h24101706.Hotel-Information) Marathon 9.2/10 Wonderful (1,110 reviews) "All rooms have an ocean view-beautiful for sure!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Wanda CA $382 CA $515 total includes taxes & fees May 3 - May 4 [](https://www.expedia.ca/Marathon-Hotels-Isla-Bella-Beach-Resort-Spa.h24101706.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-22&endDate=2026-04-23®ionId=7195&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Big Pine Key Hotel Reviews ![Kingsail Resort](https://images.trvl-media.com/lodging/2000000/1780000/1775600/1775568/96bf2fd2_y.jpg) ### Kingsail Resort 10/10 Excellent "Clean room great location, very convenient to visit keys" [](https://expedia.ca/Marathon-Hotels-Kingsail-Resort.h1775568.Hotel-Information) ![Fairfield Inn & Suites by Marriott Marathon Florida Keys](https://images.trvl-media.com/lodging/1000000/20000/19900/19823/b7875c57_y.jpg) ### Fairfield Inn & Suites by Marriott Marathon Florida Keys 10/10 Excellent "Very pleasant staff . Nice rooms that were clean. Nice towels and toiletries. Pools were clean and nice. Beautiful views. Very close to great restaurants. " [](https://expedia.ca/Marathon-Hotels-Fairfield-Inn-Suites-By-Marriott-Marathon-Florida-Keys.h19823.Hotel-Information) ![Captain Pips Marina & Hideaway](https://images.trvl-media.com/lodging/5000000/4740000/4734200/4734183/ed036535_y.jpg) ### Captain Pips Marina & Hideaway 10/10 Excellent "Perfect!!" [](https://expedia.ca/Marathon-Hotels-Captain-Pips-Marina-Hideaway.h4734183.Hotel-Information) ![Banana Bay Resort & Marina](https://images.trvl-media.com/lodging/1000000/930000/921900/921804/4b412739_y.jpg) ### Banana Bay Resort & Marina 8/10 Good "Ok" [](https://expedia.ca/Marathon-Hotels-Banana-Bay-Resort-Marina.h921804.Hotel-Information) ![Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys](https://images.trvl-media.com/lodging/11000000/10560000/10554600/10554536/30a374ce_y.jpg) ### Courtyard by Marriott Faro Blanco Resort, Marathon Florida Keys 10/10 Excellent "Our vacation was planned around just staying at the resort enjoying the pool. The bar restaurant all of that men are expectation. The room is clean. Staff was very pleasant was happy with our room nice view of the ocean. The one thing I noticed is that they seem to be a musty smell in the rooms, but I also know that with the carpets in the hallway and it is on the water that could contribute. Overall, our experience was very good." [](https://expedia.ca/Marathon-Hotels-Courtyard-By-Marriott-Marathon-Florida-Keys.h10554536.Hotel-Information) ![Parmer's Resort](https://images.trvl-media.com/lodging/6000000/5570000/5561500/5561465/bc839964_y.jpg) ### Parmer's Resort 10/10 Excellent "It's always a pleasure to stay at Parmers. Clean, friendly and easy access to your boat or Key West! We will be back. " [](https://expedia.ca/Little-Torch-Key-Hotels-Parmers-Resort.h5561465.Hotel-Information) ![Faro Blanco Resort Marathon Florida Keys, Curio by Hilton](https://images.trvl-media.com/lodging/2000000/1170000/1169600/1169583/7ec74e61_y.jpg) ### Faro Blanco Resort Marathon Florida Keys, Curio by Hilton 10/10 Excellent "The room was clean, all staff was friendly, lots of shopping close by, the food at the restaurant was delicious. Would stay there again!" [](https://expedia.ca/Marathon-Hotels-Faro-Blanco-Resort-Yacht-Club.h1169583.Hotel-Information) ![Tranquility Bay Beachfront Hotel and Resort](https://images.trvl-media.com/lodging/1000000/120000/117100/117099/854776a0_y.jpg) ### Tranquility Bay Beachfront Hotel and Resort 8/10 Good "Prepare for expensive meals and drinks." [](https://expedia.ca/Marathon-Hotels-Tranquility-Bay-Beachfront-Hotel-And-Resort.h117099.Hotel-Information) ![Coconut Cay Resort & Marina](https://images.trvl-media.com/lodging/2000000/1190000/1181000/1180935/7999b3b6_y.jpg) ### Coconut Cay Resort & Marina 6/10 Okay "The room was clean. We were next to the road so it was a little noisy. Restroom was very tiny. " [](https://expedia.ca/Marathon-Hotels-Coconut-Cay-Resort-Marina.h1180935.Hotel-Information) ## Frequently asked questions ### Why book your business-friendly hotel in Big Pine Key with Expedia? ### How can I find cheap business-friendly hotels in Big Pine Key? ## Explore a world of travel with Expedia - Lodging - More ways to book - [All Inclusive Resorts and in Atlantis Estates ](https://www.expedia.ca/Atlantis-Estates-Big-Pine-Key-Hotels-All-Inclusive-Hotel.0-n553248635976480034-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Atlantis Estates ](https://www.expedia.ca/Atlantis-Estates-Big-Pine-Key-Hotels-Cheap-Hotels.0-n553248635976480034-0-tCheapHotels.Travel-Guide-Filter-Hotels) - [Hotels with Free Airport Shuttle in Atlantis Estates ](https://www.expedia.ca/Atlantis-Estates-Big-Pine-Key-Hotels-Hotels-With-Free-Airport-Shuttle.0-n553248635976480034-0-tHotelswithFreeAirportShuttle.Travel-Guide-Filter-Hotels) - [Pet-Friendly Hotels in Atlantis Estates ](https://www.expedia.ca/Atlantis-Estates-Big-Pine-Key-Hotels-Pet-Friendly-Hotel.0-n553248635976480034-0-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - 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