A sunset over a beach with a wooden pier and a small structure on it.

5 Stars Hotels in Cow Key, Key West from CA $247

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Cow Key 5 Star Hotels

Tonight
Sep 5 - Sep 6
Tomorrow
Sep 6 - Sep 7
Next weekend
Sep 11 - Sep 13
In two weeks
Sep 18 - Sep 20
Save an average of 15% on thousands of hotels when you're signed in

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Cow Key.
Southernmost Beach Resort and Guesthouses

Southernmost Beach Resort and Guesthouses

1319 Duval Street Key West FL
CA $200
CA $326 total
Sep 13 - Sep 14
includes taxes & fees
8.6/10 Excellent! (3,569 reviews)
Southernmost Beach Resort and Guesthouses
Hyatt Centric Key West Resort and Spa

Hyatt Centric Key West Resort and Spa

601 Front St Key West FL
CA $274
CA $405 total
Sep 28 - Sep 29
includes taxes & fees
9/10 Wonderful! (1,008 reviews)
Hyatt Centric Key West Resort and Spa
Blue Flamingo Resort Key West

Blue Flamingo Resort Key West

3820 North Roosevelt Boulevard Key West FL
CA $150
CA $247 total
Sep 8 - Sep 9
includes taxes & fees
8.6/10 Excellent! (2,653 reviews)
Blue Flamingo Resort Key West
Still don't see what you're looking for?
See all properties in Cow Key.
You can also use these popular filters to refine your search.
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Cow Key

Just a short drive from the vibrant Duval Street, this tranquil key offers easy access to Key West's tropical botanical garden. Spend your days lounging at nearby Smathers Beach or exploring the Stock Island Yacht Club & Marina with its charming waterfront views.

See all hotels in Cow Key
A sunset over a beach with a wooden pier and a small structure on it.

Top Cow Key Hotel Reviews

Find out more about Cow Key

Five Star Hotels in Cow Key

There's nothing wrong with enjoying the finer things in life. Indulge yourself on your next leisure time. After all, this is one of the Top 10 locations in Expedia's portfolio. You'll join the multitudes of vacationers who have made Cow Key so fashionable in the last year. We should also mention, the hotels in this area receive outstanding marks for guest services, so you know you'll be looked after during your getaway. You deserve the great vacation you're dreaming about. Book one of Expedia's luxurious 5-star hotels in Cow Key and get ready to be pampered like never before.

Get a Great Deal on 5-Star Hotels in Cow Key

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Excellent customer care, spacious rooms, and fabulous spa offerings are all on offer. We have a huge number of hotels in the region, and all of them offer outstanding amenities. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What kind of amenities will make your stay a wonderful one? A concierge to help you plan every detail of your day? A Swedish massage to help your cares fall away? Fluffy down pillows, piping hot coffees, and even space for your family pet in some cases...these hotels have it all. Want to see for yourself? Then explore the 31,943 reviews various guests have left on Expedia and get to know these places.

Can't wait to get outside? We've got you covered. You'll find lots of attractions to see in a sprawling city like this one, like visiting art galleries and taking in live performances. Say hi to the locals—they're sure to have advice on what kind of excitement you can find in town.

Make Your Escape to Cow Key

The results are in, and Cow Key 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. This is a great time to find 5-star hotel deals in Cow Key! Don't put off your dream vacation any longer. Choose one of the 5-star hotels in Cow Key today and settle down in the lap of luxury tomorrow.

Frequently asked questions

What are the best 5-star hotels in Cow Key?
Treat yourself to a luxurious stay at Casa Marina Key West, Curio Collection by Hilton. This is one of the best 5-star hotels in Cow Key based on reviews by Expedia customers. From its plush guest rooms to its premium amenities and services, you can look forward to the best of everything.
How much does it cost to stay in a 5-star hotel in Cow Key?
There are various pricing options for a 5-star hotel in Cow Key on Expedia. The amount you pay will depend on your vacation dates, length of stay and other factors. Compare all of the available properties for your preferred dates and use our pricing and other filters to land the perfect high-end stay.
  • Search for the lowest price per night from CA $247
What makes a hotel 5 stars in Cow Key?
From gourmet restaurants and all-day gyms to swimming pools and premium bedding, the 5-star experience in Cow Key is all about relaxation and luxury. But it calls for more than just top-notch conveniences to earn a 5-star rating. Hotels also have to deliver extraordinary guest services like beauty treatments, laundry and dry cleaning and room service any time day or night.

Explore a world of travel with Expedia