Title: 4 Stars Hotels in Southeastern Indiana, United States of America from CA $139 - Find Cheap Southeastern Indiana Hotels With 4 Stars | Expedia.ca

[Southeastern Indiana Travel Guide](https://expedia.ca/Southeastern-Indiana.dx6233889)[Hotels in Southeastern Indiana](https://expedia.ca/Southeastern-Indiana-Hotels.d6233889.Travel-Guide-Hotels)[Vacation Rentals in Southeastern Indiana](https://expedia.ca/Southeastern-Indiana-Vacation-Rentals.d6233889.Travel-Guide-VacationRentals)[Flights to Southeastern Indiana](https://expedia.ca/Cheap-Flights-To-Southeastern-Indiana.d6233889.Travel-Guide-Flights)[Southeastern Indiana Car Rentals](https://expedia.ca/Car-Rentals-In-Southeastern-Indiana.d6233889.Car-Rental-Guide)[Southeastern Indiana Vacation Packages](https://expedia.ca/Southeastern-Indiana.d6233889.Destination-Travel-Guides)

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## Check availability on Southeastern Indiana 4 Star Hotels

Tonight

[Jan 29 - Jan 30](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2026-01-29&endDate=2026-01-30&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Jan 30 - Jan 31](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2026-01-30&endDate=2026-01-31&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2026-01-30&endDate=2026-02-01&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2026-02-06&endDate=2026-02-08&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Southeastern Indiana 4-star hotels

![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/aa5bcd07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/63654a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9d86b349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/23521baa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galt House Hotel Trademark Collection by Wyndham

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(4,013 reviews)

"Great hotel"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lazaro

CA $198

CA $233 total

includes taxes & fees

Feb 3 - Feb 4

[](https://www.expedia.ca/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information)

![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/78105fdd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/0bb1b93b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Outdoor pool, open 6:30 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/e2fb9d56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior detail](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/9798709f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Omni Louisville Hotel

[](https://www.expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information)

Downtown Louisville

9.2/10

Wonderful

(1,764 reviews)

"Amazing stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Erin

CA $281

CA $330 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information)

![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/5bea9d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 King Bed, Non Smoking, Corner | Living area](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/07f1fa14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/f30004bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/408d438d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Embassy Suites Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(1,153 reviews)

"Great room and breakfast. Close to several nice restaurants."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Crystal

CA $165

CA $195 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/840e31de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/f0221042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/4fd8456f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/2a2a7fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Brown Hotel

[](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

Downtown Louisville

9.4/10

Exceptional

(1,180 reviews)

"Very beautiful facility and great location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Anthony

[](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/1b9613a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges, cocktail bar, rooftop bar](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/8178d3c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/9764f52b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/91000000/90950000/90942200/90942141/w3836h2558x4y3-11fbb096.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Genevieve part of JdV by Hyatt

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Genevieve.h90942141.Hotel-Information)

Downtown Louisville

9.2/10

Wonderful

(1,034 reviews)

"Spotless room and courteous staff "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mary

CA $169

CA $199 total

includes taxes & fees

Feb 1 - Feb 2

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Genevieve.h90942141.Hotel-Information)

![Front of property](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/aaadeb96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room (Asleep in the Cyclone)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 21c Museum Hotel Louisville

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

Downtown Louisville

9.4/10

Exceptional

(1,004 reviews)

"Location and the staff was fabulous."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Madeline

CA $201

CA $243 total

includes taxes & fees

Jan 30 - Jan 31

[](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/e017e8a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite (VIP)](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/b7d53e76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/1a50697e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/330000/327000/326983/06086a53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency Louisville

[](https://www.expedia.ca/Louisville-Hotels-Hyatt-Regency-Louisville.h326983.Hotel-Information)

Downtown Louisville

8.8/10

Excellent

(1,001 reviews)

"Delicious Old Fashion. Great location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

JOHN

CA $211

CA $249 total

includes taxes & fees

Feb 7 - Feb 8

[](https://www.expedia.ca/Louisville-Hotels-Hyatt-Regency-Louisville.h326983.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/e116c623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/e68de90e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/f5558cfe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; local cuisine ](https://images.trvl-media.com/lodging/62000000/61220000/61216000/61215907/765b8556.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Grady

[](https://www.expedia.ca/Louisville-Hotels-The-Grady.h61215907.Hotel-Information)

Downtown Louisville

9.4/10

Exceptional

(1,000 reviews)

"Such an amazing hotel...restaurant is delicious! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Craig

CA $427

CA $502 total

includes taxes & fees

Feb 12 - Feb 13

[](https://www.expedia.ca/Louisville-Hotels-The-Grady.h61215907.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/c5a6934a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/19be2c84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/6f6867fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, 1 Bedroom | Living area](https://images.trvl-media.com/lodging/2000000/1120000/1111400/1111358/14a187ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Louisville Marriott Downtown

[](https://www.expedia.ca/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information)

Downtown Louisville

9.0/10

Wonderful

(1,000 reviews)

"Very nice hotel. Great stay!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Brad

CA $263

CA $310 total

includes taxes & fees

Feb 8 - Feb 9

[](https://www.expedia.ca/Louisville-Hotels-Louisville-Marriott-Downtown.h1111358.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/ac66f01b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/16484a66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![City view](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/cf849375.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch flat-screen TV with satellite channels, TV](https://images.trvl-media.com/lodging/38000000/37770000/37765700/37765616/939655b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Distil, Autograph Collection

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Distil.h37765616.Hotel-Information)

Downtown Louisville

9.6/10

Exceptional

(441 reviews)

"Exceptionally handsome hotel design, extraordinary restaurant and service, fantastic location. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Carol

CA $261

CA $307 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Louisville-Hotels-Hotel-Distil.h37765616.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/5c616865.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/cb95631e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/f1158083.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Room, 1 King Bed, Corner](https://images.trvl-media.com/lodging/108000000/107080000/107072800/107072728/c93e1deb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Bourré Bonne Louisville, Curio Collection by Hilton

[](https://www.expedia.ca/Louisville-Hotels-Canopy-By-Hilton-Louisville-Downtown.h107072728.Hotel-Information)

Downtown Louisville

9.2/10

Wonderful

(69 reviews)

"i love this place"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

THANH

CA $196

CA $231 total

includes taxes & fees

Jan 30 - Jan 31

[](https://www.expedia.ca/Louisville-Hotels-Canopy-By-Hilton-Louisville-Downtown.h107072728.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/d22f4bf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/52012810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hilton, Deluxe Suite, 1 Queen Bed, Non Smoking | Living area](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/83bc3758.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/w3839h2557x0y0-ff0d1f72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Seelbach Hilton Louisville Downtown

[](https://www.expedia.ca/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information)

Downtown Louisville

8.6/10

Excellent

(1,001 reviews)

"The area was congested but the motel was good. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Byrd

CA $179

CA $210 total

includes taxes & fees

Feb 6 - Feb 7

[](https://www.expedia.ca/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information)

![Lounge](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/3f80acf9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/89d26e2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Basic Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/d0d55041.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Signature Suite, 1 Queen Bed, Non Smoking](https://images.trvl-media.com/lodging/91000000/90960000/90953600/90953532/e9ed9b4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Stellar Suites

[](https://www.expedia.ca/Louisville-Hotels-Stellar-Suites.h90953532.Hotel-Information)

Downtown Louisville

9.6/10

Exceptional

(119 reviews)

"The check-in process was simple and easy, the room was spotless and had so many amenities. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Grace

CA $149

CA $244 total

includes taxes & fees

Feb 15 - Feb 16

[](https://www.expedia.ca/Louisville-Hotels-Stellar-Suites.h90953532.Hotel-Information)

![Property entrance](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/ee4c1d5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/5cef01cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/3ff12f20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/17000000/16890000/16881700/16881647/033ac7bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Pepin Mansion Historic B&B

[](https://www.expedia.ca/Louisville-Hotels-The-Pepin-Mansion-Historic-BB.h16881647.Hotel-Information)

New Albany

9.8/10

Exceptional

(656 reviews)

"The room was spotless and Ryan was very efficient with getting back with me when I had questions regarding parking or anything and he was very helpful because I was a late check in"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

LaTonya

CA $123

CA $139 total

includes taxes & fees

Feb 1 - Feb 2

[](https://www.expedia.ca/Louisville-Hotels-The-Pepin-Mansion-Historic-BB.h16881647.Hotel-Information)

![Seasonal outdoor pool](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/2e0c62b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Gym](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/af73a8ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Apartment, 2 Bedrooms, Non Smoking](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/48d338aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 1 Bedroom, Non Smoking | Terrace/patio](https://images.trvl-media.com/lodging/103000000/102320000/102311400/102311340/w2493h1667x0y0-491d9ec0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### CozySuites at Nulu

[](https://www.expedia.ca/Louisville-Hotels-CozySuites-At-Nulu.h102311340.Hotel-Information)

Downtown Louisville

8.2/10

Very good

(26 reviews)

"The unit was clean, all communications were timely, the property has all the amenities, and NULU is very walkable. A perfect stay! My only regret is that I wasn't able to extend the stay. Highly recommended if you're in the Louisville area "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

William

CA $93

CA $266 total

includes taxes & fees

Feb 2 - Feb 3

[](https://www.expedia.ca/Louisville-Hotels-CozySuites-At-Nulu.h102311340.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/bb9c61a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Terrace/patio](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/e4c43211.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/e576ef26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/103000000/102200000/102190400/102190334/6ec16319.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### stayAPT Suites Louisville North-Clarksville

[](https://www.expedia.ca/Louisville-Hotels-StayAPT-Suites-Louisville-N-Clarksville.h102190334.Hotel-Information)

Clarksville

9.8/10

Exceptional

(46 reviews)

"room very good i love hotel ❤️"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Kartar

[](https://www.expedia.ca/Louisville-Hotels-StayAPT-Suites-Louisville-N-Clarksville.h102190334.Hotel-Information)

![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/00e4c915.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/071da00d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/a0c5fbcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/122000000/121880000/121877400/121877336/2ec829de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Reserve on Main

[](https://www.expedia.ca/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information)

Downtown Louisville

10/10

Exceptional

(1 review)

"Incredible stay. This stay was clean and inspiring for anyone wishing to take a break and recharge. We highly recommend this stay to everyone staying in the city. "

![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg)

georgios

CA $223

CA $327 total

includes taxes & fees

Feb 2 - Feb 3

[](https://www.expedia.ca/Louisville-Hotels-The-Reserve-On-Main.h121877336.Hotel-Information)

![Family House, Multiple Beds | Private kitchen](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/3b698b60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/aebabcae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, Multiple Beds | View from room](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/fa524ab2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Family House, Multiple Beds | Living area](https://images.trvl-media.com/lodging/25000000/24380000/24372500/24372412/b618c806.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Spacious 3 BR Ranch House W Patio Yard in a Quiet Suburb

[](https://www.expedia.ca/Sellersburg-Hotels-Spacious-3-BR-Ranch-House-Wpatio-Yard-In-A-Quiet-Suburb.h24372412.Hotel-Information)

Sellersburg

9.4/10

Exceptional

(10 reviews)

"Very nice house in a nice neighborhood, spacious home environmental, felt more that at home there,"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tammy

[](https://www.expedia.ca/Sellersburg-Hotels-Spacious-3-BR-Ranch-House-Wpatio-Yard-In-A-Quiet-Suburb.h24372412.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/103000000/102380000/102374400/102374386/d5f75e71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 3 Bedrooms, Non Smoking | Living area](https://images.trvl-media.com/lodging/103000000/102380000/102374400/102374386/63eb2392.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 3 Bedrooms, Non Smoking | Living area](https://images.trvl-media.com/lodging/103000000/102380000/102374400/102374386/340ade50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Apartment, 3 Bedrooms, Non Smoking | Private kitchen](https://images.trvl-media.com/lodging/103000000/102380000/102374400/102374386/0f35f4f6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### TWO Stunning Nulu CozySuites

[](https://www.expedia.ca/Louisville-Hotels-TWO-Stunning-Nulu-CozySuites.h102374386.Hotel-Information)

Downtown Louisville

[](https://www.expedia.ca/Louisville-Hotels-TWO-Stunning-Nulu-CozySuites.h102374386.Hotel-Information)

![Free daily full breakfast](https://images.trvl-media.com/lodging/1000000/430000/427600/427527/a05fd67f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/430000/427600/427527/3bec0b16.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/1000000/430000/427600/427527/a50f3b3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/430000/427600/427527/fa2a33fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hawthorn Suites by Wyndham Louisville North

[](https://www.expedia.ca/Louisville-Hotels-Hawthorn-Suites-By-Wyndham-Louisville-North.h427527.Hotel-Information)

Jeffersonville

7.4/10

Good

(944 reviews)

"I would say that the hotel is in pretty good shape. The rooms are very nice. The parking lot however had a ton of people just hanging out. It made it a bit uncomfortable"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

alexis

[](https://www.expedia.ca/Louisville-Hotels-Hawthorn-Suites-By-Wyndham-Louisville-North.h427527.Hotel-Information)

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## Learn more about Southeastern Indiana

Live music, a scenic riverfront, and sights from Deam Lake State Recreation Area to Huber’s Orchard, Winery & Vineyards—discover it all in Southeastern Indiana.

[See all hotels in Southeastern Indiana](https://www.expedia.ca/Hotel-Search?startDate=2026-02-12&endDate=2026-02-13&adults=2&regionId=6233889)

![Belle of Louisville which includes a bay or harbour and a ferry as well as a small group of people](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high)

## Top Southeastern Indiana Hotel Reviews

## Find out more about Southeastern Indiana

If you’re looking for a spot with great rates, just-for-you amenities, and a world of luxurious little perks, the best 4 Stars hotels in Southeastern Indiana are calling your name. Known for providing first-rate service in amazing locations, each of the Southeastern Indiana 4 Stars hotels lets discerning travelers bask in an unforgettable experience.

Kick back in your spacious room. Relax in the lobby’s sumptuous surroundings. Start the day with delicious room service, and then use the complimentary body care items to freshen up before you head out for the day.

It’s all waiting for you at the top four star hotels in Southeastern Indiana. Plus, when you book with Expedia.ca, you might find a cheap deal on a 4 Stars hotel in Southeastern Indiana, United States of America, neighbourhoods near the most popular attractions, so you can see the sights and bask in the discounts all in one trip. Whether you’re planning a romantic retreat or simply want to experience everything the area has to offer, the top Southeastern Indiana hotels with 4 Stars provide everything you need to unwind in style.

## Frequently asked questions

### What are the best 4-star hotels in Southeastern Indiana?

### How much does it cost to stay in a 4-star hotel in Southeastern Indiana?

> - Search for the lowest price from CA $139

### What's the difference between 5-star and 4-star hotels in Southeastern Indiana?

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