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Your Santa Cruz Vacation
With one of our vacation packages to Santa Cruz, you'll find countless opportunities for adventure and relaxation. There's so much to experience, including its beaches and lively atmosphere. If taking in sights is part of the program during your trip to Santa Cruz, check out major attractions like Plaza 24 de Septiembre, Guembe Biocenter and Ventura Mall. Whoever you're heading away with and whatever the size of your budget, your dream Santa Cruz vacation is just clicks away with Expedia.
Top Santa Cruz Vacation Deals
Novotel Santa Cruz De La Sierra
Reviewed on Mar. 22, 2024
Hotel Cortez
Reviewed on Jan. 21, 2024
Sun Hotel
Reviewed on Apr. 1, 2024
Santa Cruz Hotel Deals
Reviewed on Apr. 17, 2024
Reviewed on Apr. 27, 2024
Reviewed on Apr. 18, 2024
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Frequently asked questions
Discover the most popular places to visit in Santa Cruz
Plaza 24 de Septiembre
The heart of Santa Cruz lies in this public square, where locals relax and tourists sightsee in a welcoming, laid-back atmosphere.
San Lorenzo Cathedral
One of the most iconic landmarks in Santa Cruz is the city’s mighty cathedral, which houses a museum displaying important artwork.
Ventura Mall
During your visit to Santa Cruz, you can find the perfect gifts to bring home at Ventura Mall. Make some time to visit the cathedral while you're in the area.