Uptown - Upper Duval

Key West
Key West Butterfly and Nature Conservatory showing flowers, animals and zoo animals

Popular places to visit

Image for Southernmost Point

Southernmost Point

4/5(160 reviews)

Snap a memorable photograph from the edge of North America at this monumental landmark.

Southernmost Point
Image for South Beach

South Beach

4/5(52 reviews)

The southernmost beach in the continental United States is a convenient sandy enclave, just minutes from the center of town.

South Beach
Image for Key West Butterfly and Nature Conservatory

Key West Butterfly and Nature Conservatory

4.5/5(19 reviews)

With about 60 species of butterfly, an indoor waterfall and a tropical rainforest, this nature conservatory is one of the most popular attractions in Key West.

Key West Butterfly and Nature Conservatory
Image for Simonton Beach

Simonton Beach

Why not spend a carefree afternoon at Simonton Beach during your travels in Key West? While you're in the area, stroll along the seaside.

Simonton Beach
Image for Nancy Forrester's Secret Garden

Nancy Forrester's Secret Garden

Visit the native and exotic animals who call Nancy Forrester's Secret Garden home during your trip to Key West. Stroll along the seaside or seek out the biking trails.

Nancy Forrester's Secret Garden
Image for City Zoo Gallery

City Zoo Gallery

You can spend an afternoon studying the exhibits at City Zoo Gallery during your travels in Key West. Discover the area's beautiful sunsets, or seek out its biking trails.

City Zoo Gallery

Things to do

Image for Southernmost Key West History and Culture Small-Group Walking Tour

Southernmost Key West History and Culture Small-Group Walking Tour

CA $54
Per adult
Southernmost Key West History and Culture Small-Group Walking Tour
Image for Florida Key West Self-Guided Walking Audio Tour

Florida Key West Self-Guided Walking Audio Tour

CA $14
Per adult
Florida Key West Self-Guided Walking Audio Tour
Image for Bahama Village Walking Tour

Bahama Village Walking Tour

CA $41
Per adult
Bahama Village Walking Tour
Image for Key West’s Old Town Treasures: A Self-Guided Audio Tour

Key West’s Old Town Treasures: A Self-Guided Audio Tour

CA $20
Per adult
Key West’s Old Town Treasures: A Self-Guided Audio Tour
Image for Florida Keys Self-Guided Driving Tour

Florida Keys Self-Guided Driving Tour

CA $21
Per adult
76% of travellers recommend
Florida Keys Self-Guided Driving Tour
Image for Morning Reef Snorkel With Unlimited Mimosas & Breakfast

Morning Reef Snorkel With Unlimited Mimosas & Breakfast

CA $62
Per adult
90% of travellers recommend
Morning Reef Snorkel With Unlimited Mimosas & Breakfast
See all activities in Key West

Uptown - Upper Duval Hotel Deals

Southernmost Beach Resort
Southernmost Beach Resort
4 out of 5
1319 Duval Street, Key West, FL
The price is CA $408 per night from Jun. 3 to Jun. 4
CA $408
CA $544 total
includes taxes & fees
Jun 3 - Jun 4
Stay at this 4-star beach hotel in Key West. Enjoy 3 outdoor pools, a full-service spa, and a beach locale. Our guests praise the pool and the bar in our reviews. ...
8.2/10 Very Good! (1,837 reviews)
"The pool and beach were awesome. The bartenders/waitress were amazing. Autum (at the pool) made the vacation. Towel and chair service could have been better. Awesome they had live music everyday. Some better then others but enjoyable and felt like on vacation"

Reviewed on May 14, 2024

Southernmost Beach Resort
The Reach Key West, Curio Collection by Hilton
The Reach Key West, Curio Collection by Hilton
4 out of 5
1435 Simonton Street, Key West, FL
The price is CA $457 per night from Jun. 5 to Jun. 6
CA $457
CA $597 total
includes taxes & fees
Jun 5 - Jun 6
Stay at this 4-star beach hotel in Key West. Enjoy a full-service spa, a private beach, and breakfast (surcharge). Our guests praise the pool and the helpful ...
8.2/10 Very Good! (616 reviews)
"My husband and I stayed for a week and it was absolutely amazing, the food was great, being served drinks at the beach was amazing. 10/10 recommend to anyone looking for a tropical getaway."

Reviewed on May 13, 2024

The Reach Key West, Curio Collection by Hilton
Southwinds Motel
Southwinds Motel
2 out of 5
1321 Simonton Street, Key West, FL
The price is CA $264 per night from Jun. 9 to Jun. 10
CA $264
CA $327 total
includes taxes & fees
Jun 9 - Jun 10
Stay at this hotel in Key West. Enjoy 2 outdoor pools, a 24-hour front desk, and daily housekeeping. Our guests praise the breakfast and the pool in our reviews. ...
8.8/10 Excellent! (1,000 reviews)
"Nice old style Florida Motel, clean, friendly staff, hot water, cold air, food and drink close by, what more do you need"

Reviewed on May 11, 2024

Southwinds Motel
The Southernmost Inn - Adults Only
The Southernmost Inn - Adults Only
3 out of 5
525 United Street, Key West, FL
The price is CA $232 per night from May 27 to May 28
CA $232
CA $323 total
includes taxes & fees
May 27 - May 28
Stay at this 3-star hotel in Key West. Enjoy free breakfast, 2 outdoor pools, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
7.6/10 Good! (1,001 reviews)
"Wonderful hotel with very nice staff. Very clean!"

Reviewed on May 14, 2024

The Southernmost Inn - Adults Only
Orchid Key Inn - Adults Only
Orchid Key Inn - Adults Only
3.5 out of 5
1004 Duval St, Key West, FL
Fully refundableReserve now, pay when you stay
The price is CA $413 per night from May 28 to May 29
CA $413
CA $464 total
includes taxes & fees
May 28 - May 29
Stay at this 3.5-star hotel in Key West. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the breakfast and the pool in our reviews. ...
9.8/10 Exceptional! (1,001 reviews)
"Great place to stay if you white"

Reviewed on May 12, 2024

Orchid Key Inn - Adults Only
Santa Maria Suites
Santa Maria Suites
4 out of 5
1401 Simonton St, Key West, FL
The price is CA $681 per night from May 16 to May 17
CA $681
CA $828 total
includes taxes & fees
May 16 - May 17
Stay at this 4-star resort in Key West. Enjoy free WiFi, 2 outdoor pools, and a fitness center. Our guests praise the pool and the helpful staff in our reviews. ...
9.6/10 Exceptional! (1,001 reviews)
worth the money
"beautiful rooms and resort. I loved our 2 bedroom, 2 bathroom, with kitchen and living room and patio room. It was expensive but gorgeous."

Reviewed on May 9, 2024

Santa Maria Suites
See all 2,737 properties in Uptown - Upper Duval
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighbourhoods around Uptown - Upper Duval

Key West Historic District

Old Town Key West

3.5/5(8 area reviews)

If you're spending some time in Old Town Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

Old Town Key West
Key West featuring a coastal town, general coastal views and a marina

Downtown Key West

If you're spending some time in Downtown Key West, Duval Street and Ernest Hemingway Home and Museum are top sights worth seeing.

Downtown Key West
Harry S. Truman Little White House which includes a house and cycling

Bahama Village

Bahama Village is noteworthy for its historic sites, and you can make a stop at top attractions like Duval Street and Key West Lighthouse and Keeper's Quarters Museum.

Bahama Village
Default Image

Casa Marina

While visiting Casa Marina, you might make a stop by sights like Clarence S. Higgs Memorial Beach Park and Florida Keys Beaches.

Casa Marina
Audubon House and Tropical Gardens featuring a house

Key West Historic District

4.5/5(156 area reviews)

Travelers to Key West Historic District praise its fantastic nightlife. If you've got some more time to explore, be sure to make a stop by Duval Street and Ernest Hemingway Home and Museum.

Key West Historic District
Great location for great pictures, very nice beach

White Street Gallery District

When in White Street Gallery District, you can plan a visit to Duval Street and Clarence S. Higgs Memorial Beach Park, some noteworthy sights in the nearby area.

White Street Gallery District

Uptown - Upper Duval

Choose two or more items and save on your trip: