Title: CA $295 Cheap Flights from Medellín (MDE) to Guayaquil (GYE) - Expedia.ca ![](https://images.trvl-media.com/place/1414/5a1b814f-6172-4234-8e22-f7c4f67d6424.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/1414/5a1b814f-6172-4234-8e22-f7c4f67d6424.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # CA $295 Cheap Flights from Medellín (MDE) to Guayaquil (GYE) [View CA $295 flight on Wed, Oct 22, 2025](https://expedia.ca/Flights-Search?trip=oneway&leg1=from:MDE,to:GYE,departure:22/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:294.30&airProductToken=AQqQAQouCMyCARIENDAwNRjsICDBMyj7gvsCMLWD-wI4T0AAWAFqAlFQcghPTEVRUFowSwouCMyCARIEMTQ0MRjBMyCUciiEhfsCMOiF-wI4T0ABWAFqAlFQcghPTEVRUFowSwouCMyCARIEMTM4NRiUciCGJiiZiPsCMM6I-wI4T0ABWAFqAlFQcghPTEVRUFowSxIKCAEQARgBKgJMQRgBIgQIARABKAIoBCgGMAE) - [Roundtrip](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Jose Maria Cordova Intl. Airport (MDE) to Jose Joaquin de Olmedo Intl. Airport (GYE) - ![Avianca](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg) Avianca [](https://www.expedia.ca/Flights-Search?leg1=from:mde,to:gye,departure:29/10/2025TANYT&leg2=from:gye,to:mde,departure:05/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}]) - ![LATAM Airlines Group](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_LA.svg) LATAM Airlines Group [](https://www.expedia.ca/Flights-Search?leg1=from:mde,to:gye,departure:29/10/2025TANYT&leg2=from:gye,to:mde,departure:05/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"LA"}}]) - ![Copa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_CM.svg) Copa [](https://www.expedia.ca/Flights-Search?leg1=from:mde,to:gye,departure:29/10/2025TANYT&leg2=from:gye,to:mde,departure:05/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"CM"}}]) ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 30% on select hotels after you book a flight\* ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.ca/login) ## Cheap flights from Medellín (MDE) to Guayaquil (GYE) Prices were available within the past 7 days and start at CA $295 for one-way flights and CA $478 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Thu, Oct 23 - Mon, Oct 27 MDE Medellin GYE Guayaquil CA $478 Roundtrip found 4 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:23/10/2025TANYT&leg2=from:GYE,to:MDE,departure:27/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:477.70&airProductToken=AQpmCjEIw5oBEgM3NjYY7CAg78QBKMiT-wIwoJT7AjhMQABYAWoFQkFTSUNyCExMQUFPWjJTCjEIw5oBEgMyNzMY78QBIIYmKImb-wIwj5z7AjhMQAFYAWoFQkFTSUNyCExMQUFPWjJTCmYKMQjDmgESAzMwMBiGJiDvxAEoyrz7AjDNvfsCOFRAAFgBagVCQVNJQ3IIVExBN1RaMlMKMQjDmgESAzE1MBjvxAEg7CAoi8f7AjDex_sCOFRAAVgBagVCQVNJQ3IIVExBN1RaMlMSCggBEAEYASoCQ00YASIECAEQASgCKAMoBDAB) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Fri, Oct 24 - Tue, Oct 28 MDE Medellin GYE Guayaquil CA $488 Roundtrip found 4 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:24/10/2025TANYT&leg2=from:GYE,to:MDE,departure:28/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:487.40&airProductToken=AQpECiAIw5oBEgMxNTcY7CAg78QBKLaf-wIwj6D7AjhFQABYAQogCMOaARIDMzAxGO_EASCGJijwoPsCMPWh-wI4RUABWAEKRAogCMOaARIDMzEzGIYmIO_EASjZxvsCMNjH-wI4VEAAWAEKIAjDmgESAzM5NxjvxAEg7CAoqcj7AjD8yPsCOFRAAVgBEgoIARABGAEqAkNNGAEiBAgBEAEoBDAB) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Thu, Oct 23 - Mon, Oct 27 MDE Medellin GYE Guayaquil CA $491 Roundtrip found 4 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:23/10/2025TANYT&leg2=from:GYE,to:MDE,departure:27/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:490.30&airProductToken=AQpmCjEIw5oBEgM3NjYY7CAg78QBKMiT-wIwoJT7AjhMQABYAWoFQkFTSUNyCExMQUFPWjJTCjEIw5oBEgMyNzMY78QBIIYmKImb-wIwj5z7AjhMQAFYAWoFQkFTSUNyCExMQUFPWjJTCmYKMQjDmgESAzIxNBiGJiDvxAEo2Lr7AjDZu_sCOExAAFgBagVCQVNJQ3IITExBQU9aMlMKMQjDmgESAzc1NhjvxAEg7CAoyLz7AjCbvfsCOExAAVgBagVCQVNJQ3IITExBQU9aMlMSCggBEAEYASoCQ00YASIECAEQASgCKAMoBDAB) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Fri, Oct 24 - Sat, Oct 25 MDE Medellin GYE Guayaquil CA $515 Roundtrip found 4 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:24/10/2025TANYT&leg2=from:GYE,to:MDE,departure:25/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:514.70&airProductToken=AQpECiAIw5oBEgMxNTcY7CAg78QBKLaf-wIwj6D7AjhFQABYAQogCMOaARIDMzAxGO_EASCGJijwoPsCMPWh-wI4RUABWAEKRAogCMOaARIDMjE0GIYmIO_EASiZpPsCMJql-wI4RUAAWAEKIAjDmgESAzgzNRjvxAEg7CAoxaX7AjCYpvsCOEVAAVgBEgoIARABGAEqAkNNGAEiBAgBEAEoBDAB) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Wed, Oct 22 - Tue, Oct 28 MDE Medellin GYE Guayaquil CA $529 Roundtrip found 4 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:22/10/2025TANYT&leg2=from:GYE,to:MDE,departure:28/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:528.60&airProductToken=AQpECiAIw5oBEgMzOTgY7CAg78QBKNeE-wIwroX7AjhXQABYAQogCMOaARIDMjU4GO_EASCGJijfhfsCMOaG-wI4V0ABWAEKRAogCMOaARIDMzEzGIYmIO_EASjZxvsCMNjH-wI4VEAAWAEKIAjDmgESAzM5NxjvxAEg7CAoqcj7AjD8yPsCOFRAAVgBEgoIARABGAEqAkNNGAEiBAgBEAEoBDAB) ![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif) Thu, Oct 23 - Mon, Oct 27 MDE Medellin GYE Guayaquil CA $534 Roundtrip found 4 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:23/10/2025TANYT&leg2=from:GYE,to:MDE,departure:27/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:533.20&airProductToken=AQqQAQouCMyCARIENDAwNRjsICDBMyiijvsCMOGO-wI4T0AAWAFqAlFQcghPTEVRUFowSwouCMyCARIEMTQ0MRjBMyCUciikkPsCMIiR-wI4T0ABWAFqAlFQcghPTEVRUFowSwouCMyCARIEMTM1MxiUciCGJiiMk_sCMMGT-wI4T0ABWAFqAlFQcghPTEVRUFowSxIKCAEQARgBKgJMQRgBIgQIARABKAIoBCgGMAE) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Thu, Oct 23 - Mon, Oct 27 MDE Medellin GYE Guayaquil CA $535 Roundtrip found 4 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:23/10/2025TANYT&leg2=from:GYE,to:MDE,departure:27/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:535.00&airProductToken=AQpmCjEIw5oBEgM3NjYY7CAg78QBKMiT-wIwoJT7AjhXQABYAWoFQkFTSUNyCFdBQUFPWjJTCjEIw5oBEgMzMDEY78QBIIYmKNCV-wIw1Zb7AjhXQAFYAWoFQkFTSUNyCFdBQUFPWjJTCmYKMQjDmgESAzMwMBiGJiDvxAEoyrz7AjDNvfsCOFRAAFgBagVCQVNJQ3IIVExBN1RaMlMKMQjDmgESAzE1MBjvxAEg7CAoi8f7AjDex_sCOFRAAVgBagVCQVNJQ3IIVExBN1RaMlMSCggBEAEYASoCQ00YASIECAEQASgCKAMoBDAB) ![LATAM Airlines Group](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/LA.gif) Thu, Oct 23 - Mon, Oct 27 MDE Medellin GYE Guayaquil CA $542 Roundtrip found 4 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:23/10/2025TANYT&leg2=from:GYE,to:MDE,departure:27/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:541.80&airProductToken=AQqQAQouCMyCARIENDAxMRjsICDBMyjTjvsCMI2P-wI4UUAAWAFqAlFQcghRTEVRUFowSwouCMyCARIEMTQ0MRjBMyCUciikkPsCMIiR-wI4UUABWAFqAlFQcghRTEVRUFowSwouCMyCARIEMTM3NxiUciCGJijIk_sCMP2T-wI4UUABWAFqAlFQcghRTEVRUFowSxIKCAEQARgBKgJMQRgBIgQIARABKAIoBCgGMAE) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Thu, Oct 23 - Mon, Oct 27 MDE Medellin GYE Guayaquil CA $548 Roundtrip found 4 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:23/10/2025TANYT&leg2=from:GYE,to:MDE,departure:27/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:547.50&airProductToken=AQpmCjEIw5oBEgM3NjYY7CAg78QBKMiT-wIwoJT7AjhXQABYAWoFQkFTSUNyCFdBQUFPWjJTCjEIw5oBEgMzMDEY78QBIIYmKNCV-wIw1Zb7AjhXQAFYAWoFQkFTSUNyCFdBQUFPWjJTCmYKMQjDmgESAzIxNBiGJiDvxAEo2Lr7AjDZu_sCOExAAFgBagVCQVNJQ3IITExBQU9aMlMKMQjDmgESAzc1NhjvxAEg7CAoyLz7AjCbvfsCOExAAVgBagVCQVNJQ3IITExBQU9aMlMSCggBEAEYASoCQ00YASIECAEQASgCKAMoBDAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Thu, Oct 23 - Mon, Oct 27 MDE Medellin GYE Guayaquil CA $625 Roundtrip found 4 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:MDE,to:GYE,departure:23/10/2025TANYT&leg2=from:GYE,to:MDE,departure:27/10/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:624.20&airProductToken=AQpqCjMIwawBEgQ4NDc1GOwgIMEzKICO-wIwvo77AjhTQABYAWoHQ0xBU1NJQ3IIU0VPQjJCUjkKMwjBrAESBDgzODkYwTMghiYokpH7AjCAkvsCOFNAAVgBagdDTEFTU0lDcghTRU9CMkJSORIKCAEQARgBKgJMUhgBIgQIARABKAIoAygEMAE) ## Find the cheapest month to fly from Medellín (MDE) to Guayaquil (GYE) ### February is typically the cheapest month to fly From CA $328 - CA $662 per traveller. Flight from Medellín to Guayaquil (MDE - GYE) route information | Origin airport | José María Córdova Intl. | | --- | --- | | Destination airport | Jose Joaquin de Olmedo Intl. | | Roundtrip price | CA $478 | | Distance | 1042 km | | Average flight time | 1 hour 50 mins | ## Rionegro to Guayaquil Flights **The easy way to book your flights from Medellín to Guayaquil**  With Expedia, it’s simple to find and book flights to Guayaquil from Medellín whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are Avianca nonstop flights to Jose Joaquin de Olmedo Intl., too.   Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Medellín to Guayaquil today, tomorrow, or this week.   **Save dollars with cheap flights from José María Córdova Intl., MDE to Jose Joaquin de Olmedo Intl., GYE**  Sort your search results by price to find great deals on your flight from Medellín to Guayaquil—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Guayaquil from Medellín currently is just CA $478 rising to CA $625.   Here are more money-saving tips:  - Fly in October when flight prices are normally at their lowest  - Book about a month to 6 weeks before you travel for the best prices to Guayaquil   - Avoid peak season and weekends when flights can cost more - Early morning and late-night flights are sometimes cheaper, so try varying your travel times  - One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free!  **Reasons to choose Expedia for your flight to Guayaquil from Medellín**  Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Guayaquil with Expedia today. ## Frequently asked questions ### How much is a flight from Medellin Airport to Jose Joaquin de Olmedo Intl. Airport (GYE)? > The lowest price advertised for a round-trip flight between Jose Maria Cordova Intl. Airport (MDE) and Jose Joaquin de Olmedo Intl. Airport (GYE) is CA $478. But you better move fast. This price is taken from fares listed within the last 7 days on Expedia for flights departing within the next year. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from Medellin Airport to Airport of Guayaquil? > Most flights can be cancelled online, but whether or not you are charged a fee varies between airlines. If you do need to cancel your trip, follow the instructions in the [Customer Service Portal](https://www.expedia.ca/helpcenter). ### How do I find cheap flights from Medellin Airport to GYE that have flexible change policies? > Select our "No change fees" filter to find flexible travel options for your flight from Medellin Airport to GYE. This allows you to lock in a fantastic price in advance and still have the freedom to reschedule without any extra fees. Just keep in mind that fare differences may still apply. ### How many hours is the flight from Jose Maria Cordova Intl. Airport (MDE) to GYE? > There are lots of ways to make the 6 hours and 18 minutes between Medellin Airport and Jose Joaquin de Olmedo Intl. Airport (GYE) go by faster. Be productive and sort through your photos or delete all those unwanted emails. A good snooze also helps pass the time! ### How far is the flight from MDE to Airport of Guayaquil? > A flight distance of just 1,050 kilometres separates Rionegro and Guayas. Once you're up in the skies, you won't get a chance to do much more than browse the magazine in your seat-back pocket. ### Which airlines fly direct from Jose Maria Cordova Intl. Airport (MDE) to Jose Joaquin de Olmedo Intl. Airport (GYE)? > Flying directly from MDE to Jose Joaquin de Olmedo Intl. Airport (GYE) is a breeze with Avianca (AV). This top airline operates 13 flights every month. ### Are MDE to Airport of Guayaquil flight tickets cheaper when they're purchased at the last minute? > Flight tickets from MDE to Jose Joaquin de Olmedo Intl. Airport (GYE) are available up to 12 months prior to departure on Expedia. And although you may occasionally score great last-minute deal, it's not something you should count on. Also, booking your flights well in advance means you'll have more options — and you can avoid getting caught in the dreaded middle seat! We're always updating our fares to bring you the best bargains, so check back often for all the latest specials. ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other ### Lodging - [5 Star Hotels in Guayaquil](https://www.expedia.ca/5Star-Guayaquil-Hotels.s50-0-d6337570.Travel-Guide-Filter-Hotels) - [Buijo Histórico Hotels](https://www.expedia.ca/Buijo-Historico-Guayaquil-Hotels.0-n553248635976385128-0.Travel-Guide-Filter-Hotels) - [Delia Hotels](https://www.expedia.ca/Delia-Guayaquil-Hotels.0-n553248635975855772-0.Travel-Guide-Filter-Hotels) - [Lgbt Friendly Hotels in Downtown Guayaquil](https://www.expedia.ca/Downtown-Guayaquil-Guayaquil-Hotels-LGBT-Friendly-Hotel.0-n6337572-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) - [Downtown Guayaquil Hotels](https://www.expedia.ca/Downtown-Guayaquil-Guayaquil-Hotels.0-n6337572-0.Travel-Guide-Filter-Hotels) - [Apartments in Duran](https://www.expedia.ca/Duran-Apartments.d6325948-aaApartments.Travel-Guide-Accommodation) - 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