CA $537 Cheap Flights from Islip (ISP) to Buffalo (BUF)

View CA $537 flight on Sat, Aug 1, 2026Opens in a new window

Popular airlines from MacArthur Airport (ISP) to Buffalo Niagara Intl. Airport (BUF)

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Cheap flights from Islip (ISP) to Buffalo (BUF)

Prices were available within the past 7 days and start at CA $537 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Frequently asked questions

How do I find cheap flights from Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
To find a cheap flight from Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.), be flexible with your dates. Traveling outside of peak vacation months and booking a mid-week flight can help you save. Early morning and late night flights are often more affordable, too. Expedia allows you to compare flight times, airlines and routes all in one place to find low fares. You can also set up Price Tracking and receive alerts when fares go up or down.
What is the best time to fly from Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The best time to fly is usually mid-week (Tuesday or Wednesday) and during early morning hours as flights tend to be cheaper, less crowded, and generally more on-time. Avoid major holidays and peak vacation seasons for smoother travel. Combining off-peak days and hours often gives the best combination of cost, comfort, and convenience.
How many flights per day from Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
There are approximately 10 connecting flights per day from Islip, NY (ISP-MacArthur) (ISP) to Buffalo, NY (BUF-Buffalo Niagara Intl.) (BUF). Some common connection points include Logan Intl. (BOS), Baltimore Washington Intl. Thurgood Marshall (BWI), and Orlando Intl. (MCO).
What is the earliest flight from Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The earliest flight from Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.) typically departs at approximately 5:00 AM local time, operated by WN. This is a seasonal service active in May. An early departure like this can help you make the most of your time at your destination. To compare early flights on Expedia, select the "Early Morning" and "Morning" filters in your search.
What day of the week has the most flights from Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
You'll typically find the most flights from Islip, NY (ISP-MacArthur) (ISP) to Buffalo, NY (BUF-Buffalo Niagara Intl.) (BUF) on a Monday, with around 9 flights available. This gives you a good selection of options for your journey. Major airlines on this route include Southwest Airlines, Spirit Airlines, and JetBlue Airways.
What are the most popular departure times for flights from Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
The most popular departure times for flights from Islip, NY (ISP-MacArthur) (ISP) to Buffalo, NY (BUF-Buffalo Niagara Intl.) (BUF) are in the morning, from 6am to 9am. About 29% of passengers prefer this time. This timing works well because you can get an early start to your day in Buffalo.
How long does it take to fly from Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
A flight from ISP to BUF with a layover takes around 6 hours 20 minutes, with the route covering approximately 326 miles. Keep in mind that actual flight times can vary due to wind patterns, weather, and air traffic.
Can you fly business or first class from Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
Select the "Business class" and "First class" filters when looking for ISP to BUF flights on Expedia. This is the easiest way to compare prices, routes and flight times for your trip.
How do I earn miles on a Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight with Expedia?
It's easy to earn miles on a Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight when you book with Expedia. Before you confirm your booking, simply select your frequent flyer program and enter your program number. As a member of One Key™, you can also earn OneKeyCash™* on top of your airline miles when you book with Expedia. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
What airports do you fly into for Buffalo from MacArthur (ISP)?
If you're planning to travel to Buffalo from MacArthur (ISP), you can fly directly into Buffalo Niagara Intl. (BUF) Some flights may connect through major hubs like Logan Intl. (BOS), Baltimore Washington Intl. Thurgood Marshall (BWI), Palm Beach Intl. (PBI) before reaching Buffalo. Compare routes and airports on Expedia to find the best flight options for your travel plans.
Is it cheaper to buy a plane ticket from Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.) at the last minute?
Typically, booking a last minute flight from Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.) will be more expensive than booking in advance. As the departure date approaches, there are usually fewer seats available which can drive up the cost. However, if there's some wiggle room with your travel dates and times, you could bag a cheap last-minute fare.
Is it cheaper to book a Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package?
Securing a Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight and hotel package is usually cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels all in one place. Select from our extensive range of stays and then add flights, activities and car rentals to your booking. Bundle everything together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.)?
If you booked your Islip, NY (ISP-MacArthur) to Buffalo, NY (BUF-Buffalo Niagara Intl.) flight within the last 24 hours, you may be able to modify or cancel it without any fees. Depending on the airline and the type of ticket you have, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal if you'd like more information.

Travel information

Origin airport
MacArthur
Destination airport
Buffalo Niagara Intl.
Distance
520 km
Average flight time
3 hours 15 mins

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Ronkonkoma to Buffalo Flights

The easy way to book your flights from Islip to Buffalo 

With Expedia, it’s simple to find and book flights to Buffalo from Islip whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Buffalo Niagara Intl., too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Islip to Buffalo today, tomorrow, or this week.  

 

Save dollars with cheap flights from MacArthur, ISP to Buffalo Niagara Intl., BUF 

Sort your search results by price to find great deals on your flight from Islip to Buffalo—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Buffalo from Islip currently is just rising to .  

Here are more money-saving tips: 

  • Fly in when flight prices are normally at their lowest 
  • Book about a month to 6 weeks before you travel for the best prices to Buffalo  
  • Avoid peak season and weekends when flights can cost more
  • Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
  • One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

 

Reasons to choose Expedia for your flight to Buffalo from Islip 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Buffalo with Expedia today.

Ronkonkoma to Buffalo Flights

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