Book The Best Hotels in Prairie City, IA for 2026 from CA $86 - Fully Refundable Options

Check prices for these dates

Tonight

Tomorrow

This weekend

Next weekend

Our top choices for Prairie City hotels

A modern lobby with a reception desk, seating area, and a fireplace.

1. Microtel Inn & Suites by Wyndham Colfax/Newton

Colfax

William

CA $94 total

includes taxes & fees

Nov 20 - Nov 21

A hotel room with two beds, a large window with a landscape view, a bathroom with a mirror and sink, and a blue carpet.

2. Days Inn by Wyndham Newton

Newton

Christine

CA $93 total

includes taxes & fees

Oct 30 - Oct 31

A hotel room with two beds, a bedside table with a lamp, and a framed picture on the wall.

3. Quality Inn Newton at I-80

Newton

Todd

CA $97 total

includes taxes & fees

Oct 31 - Nov 1

A kitchen area with wooden cabinets, a microwave, a coffee machine, and a refrigerator. There are chairs and a table in the dining area.

4. Super 8 by Wyndham Newton

Newton

Pat

CA $86 total

includes taxes & fees

Nov 20 - Nov 21

An indoor swimming pool with tiled walls, wooden ceiling beams, and lounge chairs.

5. Best Western Holiday Manor

Newton

Jennifer

CA $155 total

includes taxes & fees

Nov 5 - Nov 6

A two-story building with a green roof and beige walls, featuring a covered entrance and a flagpole with an American flag.

6. Colfax Inn

Colfax

Miriam

CA $99 total

includes taxes & fees

Oct 30 - Oct 31

An indoor swimming pool with a wooden ceiling and large windows.

7. AmericInn by Wyndham Newton

Newton

Pascal El

CA $177 total

includes taxes & fees

Nov 5 - Nov 6

A hotel room with two beds, a desk with a computer, a mirror, a window with curtains, and a painting on the wall.

8. Baymont Inn & Suites by Wyndham Newton IA

Newton

Justice

CA $90 total

includes taxes & fees

Nov 5 - Nov 6

An indoor swimming pool with clear water, tiled walls, and a no diving sign.

9. La Quinta by Wyndham Altoona Des Moines

Altoona

Wayne

CA $127 total

includes taxes & fees

Nov 15 - Nov 16

A modern bar area with a long counter, multiple bar stools, and hanging pendant lights.

10. Hampton Inn & Suites Altoona-Des Moines

Altoona

Christy

CA $173 total

includes taxes & fees

Nov 15 - Nov 16

A Holiday Inn Express & Suites hotel with a covered entrance and a brick facade.

11. Holiday Inn Express Hotel & Suites Altoona-Des Moines by IHG

Altoona

rick

CA $149 total

includes taxes & fees

Nov 29 - Nov 30

A spacious kitchen with a large island, bar stools, and a flat-screen TV mounted on the wall.

12. Cobblestone Inn & Suites - Newton

Newton

Michael

CA $166 total

includes taxes & fees

Oct 30 - Oct 31

13. Home2 Suites By Hilton Altoona Des Moines

Altoona

todd m

CA $174 total

includes taxes & fees

Nov 1 - Nov 2

A hotel reception area with a marble counter, a red carpet, and a chair with a patterned cushion.

14. Quality Inn & Suites Altoona - Des Moines

Altoona

Scott

CA $92 total

includes taxes & fees

Nov 22 - Nov 23

A reception area with a wooden wall, a reception desk, and seating with red chairs.

15. Comfort Inn Altoona-Des Moines

Altoona

Luis

CA $119 total

includes taxes & fees

Nov 22 - Nov 23

A spacious lobby with a wooden reception desk, a staircase, and a second-floor balcony.

16. Sleep Inn & Suites Pleasant Hill - Des Moines

Pleasant Hill

Yovanny

CA $94 total

includes taxes & fees

Nov 22 - Nov 23

A hotel lobby with a fireplace, seating area, and artwork on the walls.

17. Super 8 by Wyndham Altoona

Altoona

Jessica

CA $97 total

includes taxes & fees

Nov 5 - Nov 6

A hotel room with two beds, a TV, a window with blinds, a framed picture on the wall, and a bedside lamp.

18. My Place Hotel - Altoona/Des Moines, IA

Altoona

becky

CA $112 total

includes taxes & fees

Nov 8 - Nov 9

A La Quinta hotel with a modern design, featuring a prominent sign, a covered entrance, and a brick facade.

19. La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

Ankeny

Gregory J

CA $128 total

includes taxes & fees

Nov 1 - Nov 2

An indoor swimming pool with clear water, surrounded by white lounge chairs and umbrellas, under a wooden ceiling with large windows.

20. Baymont by Wyndham Pella

Pella

Lana

CA $108 total

includes taxes & fees

Nov 29 - Nov 30

View all properties

Save an average of 15% on thousands of hotels when you're signed in

Sign in

Sign up, it's free

Stay near popular Prairie City attractions

Neal Smith National Wildlife Refuge

10.0/10 (2 reviews)

You can spend time exploring the galleries in Neal Smith National Wildlife Refuge during your trip to Prairie City. While you're in the area, wander around the natural setting.

See properties

Learn more about Prairie City

Venture to sights like Neal Smith National Wildlife Refuge as you discover the local area in Prairie City.

See all hotels in Prairie City

A bison with dark brown fur and horns in a grassy field.

Top Prairie City Hotel Reviews

Des Lux Hotel

10/10 Excellent

"Great place to stay!"

Comfort Inn & Suites Event Center

10/10 Excellent

"We spent one night here, on the drive from Colorado to Ohio. The hotel is clean, quiet, well maintained and easily accessed from I-80. The late night front desk staff was great. Our room was clean and had all of the amenities we needed. We REALLY appreciate the fee for a dog being only $10. Breakfast was decent. More plant based options would be appreciated. We would definitely consider staying there again."

My Place Hotel - Altoona/Des Moines, IA

10/10 Excellent

"I arrived at the hotel early evening from a party at the Casino. The check in was quick and smooth; went to my room and turned in. I was surprised how quiet the place was. AC was working well, in fact, I had to turn it down because the room was a little too cool for me. I would stay there again."

Embassy Suites Hotel Des Moines Downtown

10/10 Excellent

"No issues what so ever. The check in and check out process were very fast and efficient. All staff were extremely friendly. The room was clean and larger than expected. Parking across the street was less expensive than originally thought, $7 instead of $10. The entrance was a little congested for a check in right before 4 pm, but they had an attendant that was moving cars through and even asked for my keys to move my car if needed while I went inside."

More cheap stays in Prairie City

Motel 6 Des Moines, IA - North

4940 NE 14th Street Des Moines IA

CA $86

CA $96 total

Nov 5 - Nov 6

includes taxes & fees

Hotels in Prairie City with star rating

Frequently asked questions

What is the best area to stay in Prairie City?

The best area to stay in Prairie City is generally around the town's central area, particularly near West 2nd Street and East 2nd Street, where most of the local amenities are located.

Prairie City is a smaller town, and its main activity revolves around its compact centre. Along West 2nd Street, you'll find local shops and eateries, giving you a sense of local life. The town square or central park area often hosts community events, providing a pleasant focal point.

For families, staying within a short drive or walk of the town's main park is a good idea. These parks often have playgrounds and open spaces for children to enjoy.

Can I cancel my hotel reservation on Expedia?

You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Prairie City.

How much is the nightly rate at a Prairie City hotel?

Prices for hotels in Prairie City often vary, but you can find a great deal from CA $86 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

Explore a world of travel with Expedia

Book Hotels in Prairie City on Expedia.com

Find hotels in Prairie City, IA from CA $86

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in Prairie City

Check prices for these dates

Filter by

Property class

Guest rating

Our top choices for Prairie City hotels

1. Microtel Inn & Suites by Wyndham Colfax/Newton

2. Days Inn by Wyndham Newton

3. Quality Inn Newton at I-80

4. Super 8 by Wyndham Newton

5. Best Western Holiday Manor

6. Colfax Inn

7. AmericInn by Wyndham Newton

8. Baymont Inn & Suites by Wyndham Newton IA

9. La Quinta by Wyndham Altoona Des Moines

10. Hampton Inn & Suites Altoona-Des Moines

11. Holiday Inn Express Hotel & Suites Altoona-Des Moines by IHG

12. Cobblestone Inn & Suites - Newton

13. Home2 Suites By Hilton Altoona Des Moines

14. Quality Inn & Suites Altoona - Des Moines

15. Comfort Inn Altoona-Des Moines

16. Sleep Inn & Suites Pleasant Hill - Des Moines

17. Super 8 by Wyndham Altoona

18. My Place Hotel - Altoona/Des Moines, IA

19. La Quinta Inn & Suites by Wyndham Ankeny IA - Des Moines IA

20. Baymont by Wyndham Pella

Stay near popular Prairie City attractions

Neal Smith National Wildlife Refuge

Learn more about Prairie City

Top Prairie City Hotel Reviews

Des Lux Hotel

More cheap stays in Prairie City

Motel 6 Des Moines, IA - North

Hotels in Prairie City with star rating

Frequently asked questions

Explore a world of travel with Expedia

Go further with the Expedia app