Book The Best Hotels in La Mesa for 2026 from CA $59 - Fully Refundable Options

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Our top choices for La Mesa hotels

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Pet friendly

Pacora River

A room with two beds, a desk with chairs, a television, and a window with blinds.

A compact kitchen with a microwave, two stools, a small refrigerator, and a flat-screen TV mounted on the wall.

A kitchen with a wooden cabinet, a TV mounted on the wall, and three bar stools.

A small kitchenette with a microwave, a coffee maker, and a refrigerator. There are two chairs and a sofa.

1. B&B Lodgings

24 de Diciembre

Pedro

CA $67

CA $74 total

includes taxes & fees

Aug 31 - Sep 1

A room with a bed, a desk with a chair, a television, and a door.

A small kitchenette with a microwave, coffee maker, and a toaster. There are two black bar stools and a TV mounted on the wall displaying movie recommendations.

A bathroom with a black toilet, a black sink, a shower curtain, and a window.

A bathroom with a bathtub, a sink, a window, and towels.

2. Tocumen Comfort Stay

24 de Diciembre

CA $63

CA $69 total

includes taxes & fees

Aug 31 - Sep 1

A room with a bed, a desk with a computer, a TV, and a fan.

A small, modern room with a kitchenette, a flat-screen TV mounted on the wall, and a herringbone-patterned wooden floor.

A room with a tiled floor, a flat-screen TV mounted on the wall, a small refrigerator, a microwave, and two bar stools.

A bathroom with a black toilet, a black bidet, a sink with a black basin, and a towel rack with folded towels.

3. PLEASANT HOSTAL PANAMA

24 de Diciembre

CA $53

CA $59 total

includes taxes & fees

Sep 10 - Sep 11

A modern cabin with a sloped roof, surrounded by trees, and a gravel path leading to the entrance.

4. Tiny Cabin

Panamá

CA $184

CA $202 total

includes taxes & fees

Sep 2 - Sep 3

A swimming pool with clear water, a poolside area with lounge chairs, and a building with large windows and doors.

A modern dining area with a wooden table and chairs, a built-in bookshelf, and a decorative hanging light fixture.

A spacious lobby with a high ceiling, modern lighting fixtures, and a glass entrance leading to a lower level.

A modern bar area with a central island, bar stools, and a television mounted on the ceiling.

5. Crowne Plaza Panama Airport by IHG

Tocumen

Tameka

CA $175

CA $201 total

includes taxes & fees

Sep 5 - Sep 6

A bedroom with a large bed, a nightstand, a dresser, and decorative wall art.

A multi-level interior with a wooden staircase, decorative lighting, and a blue wall.

An outdoor dining area with two stone statues, string lights, and a covered seating area.

A cozy living room with a television, a lamp, and a sofa.

6. ORHO Hotel Boutique 15 Minutes from PTY Airport

Tocumen

Juan

CA $136

CA $178 total

includes taxes & fees

Sep 10 - Sep 11

A hotel room with two single beds, a small table with a chair, a TV mounted on the wall, and a marble-patterned headboard.

A rectangular swimming pool with blue tiles and a brick border.

A modern interior with a staircase, a seating area with a bench and tables, and a counter with a sign reading "NISATO".

A two-story building with a sign reading "HOTEL EXPRESS INN".

7. Express Inn Panama International Airport Hostel

Tocumen

Evelyn

CA $68

CA $75 total

includes taxes & fees

Aug 27 - Aug 28

8. Riande Aeropuerto Hotel & Casino

Tocumen

Elizabeth

CA $149

CA $164 total

includes taxes & fees

Aug 31 - Sep 1

9. Swette Love 10 Minutes From the Airport Tocumen

Las Mañanitas

CA $80

CA $104 total

includes taxes & fees

Sep 6 - Sep 7

A buffet with various food items including fruits, juices, and cheeses.

A modern hotel lobby with a sectional sofa, a glass coffee table, and a vibrant green wall mural.

A gym with treadmills, weight machines, and dumbbells.

An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.

10. Courtyard by Marriott Panama Metromall

San Antonio

Khadija

CA $135

CA $148 total

includes taxes & fees

Aug 28 - Aug 29

A hotel entrance with a central water feature, seating areas, and potted plants.

A pool with a central water feature, surrounded by seating areas and potted plants.

A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.

The entrance of The Santa Maria with a covered walkway and a view of the interior.

11. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Juan Diaz

Carlos

CA $370

CA $408 total

includes taxes & fees

Aug 28 - Aug 29

A rooftop pool with a city view, lounge chairs, and a clear sky.

A modern lounge area with a bar, seating, and a large window offering a city view.

A modern kitchen with a marble countertop, a refrigerator, and a dining area with a table set for two.

A modern lobby with a curved grey sofa, a round coffee table, and an orange armchair. There are potted plants and a reception desk in the background.

12. Corporate Stays Arcadia | Executive Furnished Apartments

Costa del Este

Murietta

CA $123

CA $209 total

includes taxes & fees

Sep 15 - Sep 16

A rooftop pool with a city view, modern architecture, and outdoor seating.

A modern hotel room with a large bed, a desk, and a view of the cityscape.

A spacious lobby with a modern design, featuring a sofa, chairs, and large potted plants.

A high-rise building with a view of the ocean and a parking area with palm trees.

13. The Westin Panama

Costa del Este

RAMON

CA $306

CA $337 total

includes taxes & fees

Sep 19 - Sep 20

A swimming pool with lounge chairs, surrounded by greenery and tall buildings in the background.

A gym with various exercise equipment, a brick wall, and a ceiling with wooden slats.

A modern apartment with a kitchen, dining area, and living room.

A modern living room with a sofa, a dining table, and a staircase leading to an upper level.

14. Apex Executive Apartments - Dovle

Parque Lefevre

CA $157

CA $293 total

includes taxes & fees

Aug 28 - Aug 29

A modern outdoor swimming pool with a clear view of a tall building in the background.

A modern apartment with a living area, kitchen, and a staircase leading to an upper level.

A modern reception area with a brick wall, wooden paneling, and a neon sign.

A modern urban pathway lined with lush greenery and a pool, leading to a building with balconies and a clear sky.

15. Dovle Residences by HMS-Preferred Member

San Francisco

Jessica

CA $186

CA $205 total

includes taxes & fees

Aug 26 - Aug 27

A modern living room with a sofa, coffee table, and a staircase leading to an upper floor.

A modern hotel room with a wooden desk, a chair, a bed, and a staircase.

A gym with various exercise equipment, including treadmills and weight machines.

A modern apartment with a kitchen, living area, and a balcony with a pool view.

16. Stylish Apartment With Pool Gym in Panama

San Francisco

Stepp

CA $158

CA $200 total

includes taxes & fees

Aug 26 - Aug 27

A modern living room with a sofa, a coffee table with flowers, a TV, and a large window with a city view.

A dining area with a table set for four, large windows with a cityscape view, a small side table with a lamp, and a television on a stand.

A modern living room with a large window, a sofa, a coffee table, a TV on a wooden cabinet, and a dining table with chairs.

A bedroom with a large bed, a view through a sliding door, and two framed pictures on the wall.

17. Boutique Apartments Panamá Coco del Mar

San Francisco

Hugo

CA $84

CA $287 total

includes taxes & fees

Aug 26 - Aug 27

A buffet with various food items and a decorative plant.

A gym with treadmills, weight machines, and a red carpet.

A hotel with a swimming pool, outdoor seating, and a modern architectural design.

A spa area with a hot tub, candles, and a curved bench.

18. Sheraton Grand Panama

San Francisco

Luis

CA $241

CA $266 total

includes taxes & fees

Sep 2 - Sep 3

An elevator with a digital display showing the number 3, a sign above it reading 'PISO-3', and two safety signs on the wall.

A room with a wooden panel wall, a large mirror, and a coiled cable on a stand.

A bedroom with a bed, a desk with a chair, a small wooden nightstand, and a window with sheer curtains.

A living room with a sectional sofa, a ceiling fan, a decorative wall piece, and a window with blinds.

19. Charming 3 Bedroom Apartment in San Miguelito, Panama City

José Domingo Espinar

caleb

CA $97

CA $134 total

includes taxes & fees

Aug 30 - Aug 31

A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

A modern interior with two escalators leading to upper floors, a prominent 'a loft Panama' sign, and a staircase with glass railings.

A spacious lobby with a pool table, comfortable seating areas, and a bar with a variety of beverages.

A modern rooftop pool with a view of high-rise buildings at night.

20. Aloft by Marriott Panama

San Francisco

Mauricio

CA $165

CA $181 total

includes taxes & fees

Sep 6 - Sep 7

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Top La Mesa Hotel Reviews

Courtyard by Marriott Panama Metromall

10/10 Excellent

"Room was spotless and staff were friendly and willing to help. Even booked us a taxi to the airport."

Riande Aeropuerto Hotel & Casino

10/10 Excellent

"Our favorite place to stay in PC!"

Corporate Stays Arcadia | Executive Furnished Apartments

10/10 Excellent

"Perhaps this is the best economical stay in Panama City. The price is very reasonable, the hosts are outstanding and always helpful, the room exceptionally clean. It’s always nice to have a full kitchen available for food preparation, and each room features a fully supplied kitchen. The view from the window is extraordinary. What more can I say? It’s always a comfortable stay and the place that I want to go when I travel to Panama City."

Aloft by Marriott Panama

10/10 Excellent

"This is a well located hotel close to the biggest shopping mall in Panama’ City. The staff is very kind and friendly. The breakfast has a lot of options with fresh food and good buffet. We stayed four days before to return to the USA and Panamá has very kind people. We recommend this place."

Ramada Plaza by Wyndham Panama Punta Pacifica

8/10 Good

"This is a very nice walkable hotel location, close to a variety of restaurants, a large Mall that has a grocery store, some convince stores around, Bus stop & good for UBER pickups. The pool is well maintained and the breakfast is good with daily variety. Staff was pleasant & helpful. I will return."

Dovle Residences by HMS-Preferred Member

10/10 Excellent

"The places was amazing the cleaning on point good breakfast wonderful people definitely going back"

ORHO Hotel Boutique 15 Minutes from PTY Airport

10/10 Excellent

"Everything was great. We had a great experience very clean. He had a lot of places around so he can go to 10 out of 10."

B&B Lodgings

10/10 Excellent

"All the staff people was very good"

The Westin Panama

8/10 Good

"Un hotel decente…."

More cheap stays in La Mesa

Tocumen Comfort Stay

07168 24 de Diciembre Panama

CA $63

CA $69 total

Aug 31 - Sep 1

includes taxes & fees

B&B Lodgings

C. Tercera El Valle de Cerro Azul 24 de Diciembre Panamá Province

CA $67

CA $74 total

Aug 31 - Sep 1

includes taxes & fees

8/10 Very good! (95 reviews)

Orho Hotel Boutique 15 Minutes From PTY Airport

Calle Aeropuerto Tocumen Panamá Province

CA $153

CA $169 total

Sep 20 - Sep 21

includes taxes & fees

ORHO Hotel Boutique 15 Minutes from PTY Airport

Av. Domingo Díaz Tocumen Provincia de Panamá

CA $136

CA $178 total

Sep 10 - Sep 11

includes taxes & fees

8.8/10 Excellent! (185 reviews)

Cozy Urban Loft 1br Near Coast

Panama City Panamá Province

CA $157

CA $198 total

Aug 28 - Aug 29

includes taxes & fees

Apex Executive Apartments - Dovle

Vía Cincuentenario 313 Panamá Panamá

CA $157

CA $293 total

Aug 28 - Aug 29

includes taxes & fees

Frequently asked questions

Where is the best place to stay in La Mesa?

Crowne Plaza Panama Airport by IHG, located 9.9 mi (15.9 km) from the heart of La Mesa, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Aloft by Marriott Panama and Courtyard by Marriott Panama Metromall. See all available top hotels, or vacation rentals in La Mesa.

What are some of the best vacation home rentals in La Mesa?

Cozy 3-bedroom townhome with WiFi, AC in fabulous Panamá: You might want to consider this vacation home rental near La Mesa, which is equipped with a selection of books, air-conditioning, and laundry facilities to help you feel comfortable during your stay. It has 3 bedrooms as well as a kitchen with a fridge, an oven, and a microwave, so you can cook with friends or family. See all vacation rentals in La Mesa.

If I need to cancel my hotel reservation in La Mesa, will I receive a refund?

Yes, the majority of room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in La Mesa.

What is staying in La Mesa like?

Visitors to La Mesa are sure to find plenty to explore and enjoy. There are 582 hotels and other accommodations in the surrounding area. Find out more about La Mesa.

What are the top places to visit in La Mesa?

Places to visit in the wider area include Metromall Panama, Los Pueblos Commercial Center, and Estadio Rommel Fernandez. You'll also find Chagres National Park and Chepo Youth Recreation Center in the area. Check out what more to see and do in Expedia's La Mesa guide.

What's the weather like in La Mesa?

The hottest months are usually April and March with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in La Mesa are July, August, October, and June, with each month seeing an average of 14 inches of rainfall.

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Find hotels in La Mesa from CA $59

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in La Mesa

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for La Mesa hotels

1. B&B Lodgings

2. Tocumen Comfort Stay

3. PLEASANT HOSTAL PANAMA

4. Tiny Cabin

5. Crowne Plaza Panama Airport by IHG

6. ORHO Hotel Boutique 15 Minutes from PTY Airport

7. Express Inn Panama International Airport Hostel

8. Riande Aeropuerto Hotel & Casino

9. Swette Love 10 Minutes From the Airport Tocumen

10. Courtyard by Marriott Panama Metromall

11. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

12. Corporate Stays Arcadia | Executive Furnished Apartments

13. The Westin Panama

14. Apex Executive Apartments - Dovle

15. Dovle Residences by HMS-Preferred Member

16. Stylish Apartment With Pool Gym in Panama

17. Boutique Apartments Panamá Coco del Mar

18. Sheraton Grand Panama

19. Charming 3 Bedroom Apartment in San Miguelito, Panama City

20. Aloft by Marriott Panama

Top La Mesa Hotel Reviews

Courtyard by Marriott Panama Metromall

Riande Aeropuerto Hotel & Casino

Corporate Stays Arcadia | Executive Furnished Apartments

Aloft by Marriott Panama

Ramada Plaza by Wyndham Panama Punta Pacifica

Dovle Residences by HMS-Preferred Member

ORHO Hotel Boutique 15 Minutes from PTY Airport

B&B Lodgings

The Westin Panama

More cheap stays in La Mesa

Tocumen Comfort Stay

B&B Lodgings

Orho Hotel Boutique 15 Minutes From PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport

Cozy Urban Loft 1br Near Coast

Apex Executive Apartments - Dovle

Frequently asked questions

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