Book The Best Hotels in La Mesa for 2026 from CA $59 - Fully Refundable Options

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Our top choices for La Mesa hotels

A room with two beds, a desk with chairs, a television, and a window with blinds.

A kitchen with a wooden cabinet, a TV mounted on the wall, and three bar stools.

A bathroom with a sink, toilet, and shower curtain.

A small kitchenette with a microwave, a coffee maker, and a refrigerator. There are two chairs and a sofa.

1. B&B Lodgings

24 de Diciembre

Pedro

CA $68

CA $75 total

includes taxes & fees

Sep 1 - Sep 2

A room with a bed, a desk with a chair, a television, and a door.

A bathroom with a black toilet, a black sink, a shower curtain, and a window.

A small kitchenette with a microwave, coffee maker, and a toaster. There are two black bar stools and a TV mounted on the wall displaying movie recommendations.

A bathroom with a bathtub, a sink, a window, and towels.

2. Tocumen Comfort Stay

24 de Diciembre

CA $63

CA $70 total

includes taxes & fees

Sep 1 - Sep 2

A room with a bed, a desk with a computer, a TV, and a fan.

A bathroom with a black toilet, a black bidet, a sink with a black basin, and a towel rack with folded towels.

A bedroom with two beds, a ceiling fan, an air conditioning unit, and a mirror on the wall.

A room with a tiled floor, a flat-screen TV mounted on the wall, a small refrigerator, a microwave, and two bar stools.

3. PLEASANT HOSTAL PANAMA

24 de Diciembre

CA $54

CA $59 total

includes taxes & fees

Oct 1 - Oct 2

A modern dining area with a wooden table and chairs, a built-in bookshelf, and a decorative hanging light fixture.

A spacious lobby with a high ceiling, modern lighting fixtures, and a glass entrance leading to a lower level.

A modern restaurant with checkered flooring, wooden chairs, and large windows offering a view of greenery.

A hotel with a modern facade, multiple flags, and a well-lit entrance.

4. Crowne Plaza Panama Airport by IHG

Tocumen

Valeria

CA $177

CA $203 total

includes taxes & fees

Sep 26 - Sep 27

A bedroom with a large bed, a nightstand, a dresser, and decorative wall art.

A multi-level interior with a wooden staircase, decorative lighting, and a blue wall.

An outdoor dining area with two stone statues, string lights, and a covered seating area.

A cozy living room with a television, a lamp, and a sofa.

5. ORHO Hotel Boutique 15 Minutes from PTY Airport

Tocumen

Juan

CA $139

CA $182 total

includes taxes & fees

Sep 1 - Sep 2

6. Riande Aeropuerto Hotel & Casino

Tocumen

Sheldon

CA $127

CA $140 total

includes taxes & fees

Sep 2 - Sep 3

A hotel room with two single beds, a small table with a chair, a TV mounted on the wall, and a marble-patterned headboard.

A rectangular swimming pool with blue tiles and a brick border.

A modern interior with a staircase, a seating area with a bench and tables, and a counter with a sign reading "NISATO".

A modern building with a tiled patio, a mural with palm trees and the word "Panama," and a large window.

7. Express Inn Panama International Airport Hostel

Tocumen

Evelyn

CA $69

CA $76 total

includes taxes & fees

Sep 3 - Sep 4

A dining area with a table set for two, chairs, a TV mounted on the wall, a decorative plant, and a window with decorative bars.

8. Swette Love 10 Minutes From the Airport Tocumen

Las Mañanitas

CA $81

CA $105 total

includes taxes & fees

Sep 6 - Sep 7

A modern cabin with a sloped roof, surrounded by trees, and a gravel path leading to the entrance.

9. Tiny Cabin

Panamá

CA $186

CA $204 total

includes taxes & fees

Sep 2 - Sep 3

A buffet with various food items including fruits, juices, and cheeses.

A modern hotel lobby with a sectional sofa, a glass coffee table, and a vibrant green wall mural.

An aerial view of a rectangular swimming pool with two lounge chairs and a ladder.

A hotel reception area with a wooden reception desk, seating area with chairs and ottomans, and a large window providing natural light.

10. Courtyard by Marriott Panama Metromall

San Antonio

Stephen

CA $141

CA $155 total

includes taxes & fees

Sep 5 - Sep 6

A hotel entrance with a central water feature, seating areas, and potted plants.

A pool with a central water feature, surrounded by seating areas and potted plants.

A spacious lobby with a wooden ceiling, a central wooden table surrounded by potted plants, and a marble wall with a large window in the background.

An outdoor dining area with wicker chairs and tables, a bar with bottles, and a pool in the background.

11. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Juan Diaz

PAULA

CA $374

CA $411 total

includes taxes & fees

Sep 7 - Sep 8

A rooftop pool with a city view, lounge chairs, and a clear sky.

A modern kitchen with a marble countertop, a refrigerator, and a dining area with a table set for two.

A modern lounge area with a bar, seating, and a large window offering a city view.

A modern lobby with a curved grey sofa, a round coffee table, and an orange armchair. There are potted plants and a reception desk in the background.

12. Corporate Stays Arcadia | Executive Furnished Apartments

Costa del Este

Rame

CA $150

CA $175 total

includes taxes & fees

Sep 30 - Oct 1

A rooftop pool with a city view, modern architecture, and outdoor seating.

A modern hotel room with a large bed, a desk, and a view of the cityscape.

A spacious lobby with a modern design, featuring a sofa, chairs, and large potted plants.

A narrow street with multi-story buildings, balconies, and a central building with a red roof.

13. The Westin Panama

Costa del Este

RAMON

CA $286

CA $314 total

includes taxes & fees

Sep 26 - Sep 27

A swimming pool with lounge chairs, surrounded by greenery and tall buildings in the background.

A gym with various exercise equipment, a brick wall, and a ceiling with wooden slats.

A modern apartment with a kitchen, dining area, and living room.

A modern living room with a sofa, a dining table, and a staircase leading to an upper level.

14. Apex Executive Apartments - Dovle

Parque Lefevre

CA $133

CA $268 total

includes taxes & fees

Sep 7 - Sep 8

A modern outdoor swimming pool with a clear view of a tall building in the background.

A modern reception area with a brick wall, wooden paneling, and a neon sign.

A modern apartment with a living area, kitchen, and a staircase leading to an upper level.

A modern urban pathway lined with lush greenery and a pool, leading to a building with balconies and a clear sky.

15. Dovle Residences by HMS-Preferred Member

San Francisco

Jessica

CA $197

CA $218 total

includes taxes & fees

Sep 7 - Sep 8

A modern living room with a sofa, coffee table, and a staircase leading to an upper floor.

A gym with various exercise equipment, including treadmills and weight machines.

A modern apartment with a kitchen, living area, and a balcony with a pool view.

A modern hotel room with a wooden desk, a chair, a bed, and a staircase.

16. Stylish Apartment With Pool Gym in Panama

San Francisco

Stepp

CA $180

CA $246 total

includes taxes & fees

Sep 12 - Sep 13

A modern living room with a sofa, a coffee table with flowers, a TV, and a large window with a city view.

A dining area with a table set for four, large windows with a cityscape view, a small side table with a lamp, and a television on a stand.

A modern living room with a sofa, a TV, and a dining area with a table and chairs.

A modern living room with a large window, a sofa, a coffee table, a TV on a wooden cabinet, and a dining table with chairs.

17. Boutique Apartments Panamá Coco del Mar

San Francisco

Hugo

CA $67

CA $269 total

includes taxes & fees

Sep 13 - Sep 14

An elevator with a digital display showing the number 3, a sign above it reading 'PISO-3', and two safety signs on the wall.

A living room with a sectional sofa, a ceiling fan, a decorative wall piece, and a window with blinds.

A room with a wooden panel wall, a large mirror, and a coiled cable on a stand.

A dining area with a round table, four chairs, a ceiling fan, and a wall-mounted painting.

18. Charming 3 Bedroom Apartment in San Miguelito, Panama City

José Domingo Espinar

caleb

CA $98

CA $135 total

includes taxes & fees

Sep 1 - Sep 2

A buffet with various food items and a decorative plant.

A gym with treadmills, weight machines, and a red carpet.

A spa area with a hot tub, candles, and a curved bench.

A spacious lobby with a high ceiling, a glass railing on the upper level, and a seating area with modern furniture.

19. Sheraton Grand Panama

San Francisco

Luis

CA $244

CA $268 total

includes taxes & fees

Sep 9 - Sep 10

A modern hotel with a prominent entrance, multiple floors, and a well-lit facade.

A modern lounge area with seating, a bar, and a staircase.

A spacious lobby with a pool table, comfortable seating areas, and a bar with a variety of beverages.

A modern interior with two escalators leading to upper floors, a prominent 'a loft Panama' sign, and a staircase with glass railings.

20. Aloft by Marriott Panama

San Francisco

Shaniyah

CA $166

CA $182 total

includes taxes & fees

Sep 25 - Sep 26

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Top La Mesa Hotel Reviews

Ramada Plaza by Wyndham Panama Punta Pacifica

8/10 Good

"The room was clean and the staff helped with any request I had. Also the breakfast variety was good enough for the number of days we stayed. The pool chemical made it impossible to open our eyes under water. It burned so much...that was my only issue."

Dovle Residences by HMS-Preferred Member

10/10 Excellent

"Modern and clean, including a pool and gym with stunning view. Staff were wonderful. Basic but good breakfast included. Better than a hotel."

ORHO Hotel Boutique 15 Minutes from PTY Airport

10/10 Excellent

"Excelente atención! Totalmente recomendado. Tanto el hotel como el personal 10/10"

Breath-taking City Center

10/10 Excellent

"Nice place good location but is old building"

Aloft by Marriott Panama

10/10 Excellent

"It was a great stay"

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

10/10 Excellent

"Excellent"

Boutique Apartments Panamá Coco del Mar

8/10 Good

"the only issue we had was knowing how to open the door, had to contact host for video to be sent, i think the host should send the video prior to check in to avoid that type of issue again otherwise everything else was great!"

B&B Lodgings

10/10 Excellent

"All the staff people was very good"

More cheap stays in La Mesa

Tocumen Comfort Stay

07168 24 de Diciembre Panama

CA $63

CA $70 total

Sep 1 - Sep 2

includes taxes & fees

B&B Lodgings

C. Tercera El Valle de Cerro Azul 24 de Diciembre Panamá Province

CA $68

CA $75 total

Sep 1 - Sep 2

includes taxes & fees

8/10 Very good! (96 reviews)

Orho Hotel Boutique 15 Minutes From PTY Airport

Calle Aeropuerto Tocumen Panamá Province

CA $155

CA $171 total

Sep 25 - Sep 26

includes taxes & fees

ORHO Hotel Boutique 15 Minutes from PTY Airport

Av. Domingo Díaz Tocumen Provincia de Panamá

CA $139

CA $182 total

Sep 1 - Sep 2

includes taxes & fees

9/10 Wonderful! (186 reviews)

Cozy Urban Loft 1br Near Coast

Panama City Panamá Province

CA $130

CA $192 total

Sep 12 - Sep 13

includes taxes & fees

Apex Executive Apartments - Dovle

Vía Cincuentenario 313 Panamá Panamá

CA $133

CA $268 total

Sep 7 - Sep 8

includes taxes & fees

Frequently asked questions

Where is the best place to stay in La Mesa?

Crowne Plaza Panama Airport by IHG, located 9.9 mi (15.9 km) from the heart of La Mesa, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Aloft by Marriott Panama and Courtyard by Marriott Panama Metromall. See all available top hotels, or vacation rentals in La Mesa.

What are some of the best vacation home rentals in La Mesa?

Cozy 3-bedroom townhome with WiFi, AC in fabulous Panamá: You might want to consider this vacation home rental near La Mesa, which is equipped with a selection of books, air-conditioning, and laundry facilities to help you feel comfortable during your stay. It has 3 bedrooms as well as a kitchen with a fridge, an oven, and a microwave, so you can cook with friends or family. See all vacation rentals in La Mesa.

If I need to cancel my hotel reservation in La Mesa, will I receive a refund?

Yes, the majority of room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in La Mesa.

What is staying in La Mesa like?

Visitors to La Mesa are sure to find plenty to explore and enjoy. There are 583 hotels and other accommodations in the surrounding area. Find out more about La Mesa.

What are the top places to visit in La Mesa?

Places to visit in the wider area include Metromall Panama, Los Pueblos Commercial Center, and Estadio Rommel Fernandez. You'll also find Chagres National Park and Chepo Youth Recreation Center in the area. Check out what more to see and do in Expedia's La Mesa guide.

What's the weather like in La Mesa?

The hottest months are usually April and March with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in La Mesa are July, August, October, and June, with each month seeing an average of 14 inches of rainfall.

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Find hotels in La Mesa from CA $59

Change your mind

Treat yourself

Be picky

Go beyond your typical stay in La Mesa

Check prices for these dates

Filter by

Star rating

Guest rating

Our top choices for La Mesa hotels

1. B&B Lodgings

2. Tocumen Comfort Stay

3. PLEASANT HOSTAL PANAMA

4. Crowne Plaza Panama Airport by IHG

5. ORHO Hotel Boutique 15 Minutes from PTY Airport

6. Riande Aeropuerto Hotel & Casino

7. Express Inn Panama International Airport Hostel

8. Swette Love 10 Minutes From the Airport Tocumen

9. Tiny Cabin

10. Courtyard by Marriott Panama Metromall

11. The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

12. Corporate Stays Arcadia | Executive Furnished Apartments

13. The Westin Panama

14. Apex Executive Apartments - Dovle

15. Dovle Residences by HMS-Preferred Member

16. Stylish Apartment With Pool Gym in Panama

17. Boutique Apartments Panamá Coco del Mar

18. Charming 3 Bedroom Apartment in San Miguelito, Panama City

19. Sheraton Grand Panama

20. Aloft by Marriott Panama

Top La Mesa Hotel Reviews

Ramada Plaza by Wyndham Panama Punta Pacifica

Dovle Residences by HMS-Preferred Member

ORHO Hotel Boutique 15 Minutes from PTY Airport

Breath-taking City Center

Aloft by Marriott Panama

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Boutique Apartments Panamá Coco del Mar

B&B Lodgings

More cheap stays in La Mesa

Tocumen Comfort Stay

B&B Lodgings

Orho Hotel Boutique 15 Minutes From PTY Airport

ORHO Hotel Boutique 15 Minutes from PTY Airport

Cozy Urban Loft 1br Near Coast

Apex Executive Apartments - Dovle

Frequently asked questions

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