South Central Houston
Houston
Visit South Central Houston
Stay near popular South Central Houston attractions
Things to do
Houston: Space Center Houston Admission Ticket
CA $42
per adult
92% of travellers recommend
NASA's Space Center & Official Houston City Tour with tickets
CA $140
per adult
92% of travellers recommend
Houston: Guided City Tour by an Open-Top Double Decker Bus
CA $56
per adult
98% of travellers recommend
Houston's Official City & Mural Tour!
CA $56
per adult
88% of travellers recommend
Houston: Houston Botanic Garden Entry Ticket
CA $17
per adult
South Central Houston Hotel Deals
Hotel Zaza Houston Museum District
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
The price is CA $254 per night from Sep 2 to Sep 3
CA $254
CA $351 total
Sep 2 - Sep 3
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, a full-service spa, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. ...
9.2/10 Wonderful! (1,017 reviews)
"Great pool!"
Reviewed on Aug 22, 2026
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
The price is CA $111 per night from Sep 6 to Sep 7
CA $111
CA $131 total
Sep 6 - Sep 7
includes taxes & fees
Book a stay at this luxury hotel in Houston. Enjoy free WiFi, 2 restaurants, and 2 bars/lounges. Our guests praise the helpful staff and the clean rooms in our ...
The Westin Houston Medical Center/Museum District
1709 DRYDEN ROAD Houston TX
The price is CA $198 per night from Sep 6 to Sep 7
CA $198
CA $246 total
Sep 6 - Sep 7
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), room service, and a 24-hour health club. Our guests praise the helpful staff ...
9.2/10 Wonderful! (1,195 reviews)
"The hotel views at sunset and night are gorgeous from the pool or terrace. The food is actually good, not hospital like at all. Staff is very friendly and you really get treated nice. Room is clean and beds are comfy. Second stay and will not be my last."
Reviewed on Aug 23, 2026
InterContinental Houston by IHG
6750 Main St Houston TX
The price is CA $222 per night from Aug 29 to Aug 30
CA $222
CA $287 total
Aug 29 - Aug 30
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy free WiFi, breakfast (surcharge), and a free area shuttle. Our guests praise the helpful staff ...
9.4/10 Exceptional! (1,011 reviews)
"Awesome staff"
Reviewed on Aug 22, 2026
Houston Marriott Medical Center/Museum District
6580 Fannin Street Houston TX
The price is CA $197 per night from Aug 28 to Aug 29
CA $197
CA $274 total
Aug 28 - Aug 29
includes taxes & fees
Book a stay at this business-friendly hotel in Houston. Enjoy breakfast (surcharge), a free area shuttle, and room service. Our guests praise the helpful staff ...
Downtowner Inns - Houston Downtown
2510 Hamilton St Houston TX
The price is CA $129 per night from Sep 23 to Sep 24
CA $129
CA $151 total
Sep 23 - Sep 24
includes taxes & fees
Stay at this hotel in Houston. Enjoy free breakfast, free WiFi, and free parking. Popular attractions Toyota Center and Daikin Park are located nearby.
9.2/10 Wonderful! (230 reviews)
"The location a walking distance to the convention center is perfect. The price is reasonable, breakfast helpful. Can park there for free not true of the hotels at the convention center. Rooms very clean and comfortable. It is a good sleeper hotel that convention folks need to take advantage of. The ..."
Reviewed on Aug 20, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Where to stay in South Central Houston
Find the best South Central Houston areas and neighborhoods for the activities you enjoy most. Learn more about South Central Houston
Learn more about South Central Houston
Downtown Houston
Known for its abundant dining options and live music, there's plenty to explore in Downtown Houston. Top attractions like Daikin Park and Toyota Center are major draws, and you can catch the metro at Central Station Main or Main Street Square Station to see more of the city.
The Galleria
Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower.
Texas Medical Center
Well-liked for its restaurants, museums, and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo is a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Photo by George Zimzores
Open Photo by George Zimzores
Houston Central Business District
If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station.
Montrose
Unique features of Montrose include the theaters and museums. Make a stop by Menil Collection or The Chapel of St. Basil while you're exploring the area.
South Central Houston
Explore a world of travel with Expedia
- Oceanfront Hotels in Houston
- 5 Star Hotels in Houston
- Luxury Hotels in Houston
- Hotels near NRG Stadium
- Texas Medical Center Hotels
- Beach Hotel Hotels in Houston
- Hotels near George Bush Intercontinental
- The Galleria Hotels
- Hotels with an Indoor Pool in Houston
- Hotels near MD Anderson Cancer Center
- Hotels near George R. Brown Convention Center
- All Inclusive Resorts and in Houston
- Hotels near Rice University
- Family Hotels in Houston
- Hotels with Kitchenettes in Houston
- Spa Hotels in Houston
- Midtown Hotels
- Downtown Houston Hotels
- Hotels with Waterslides in Houston
- Hotels near Daikin Park
- Cheap Hotels in Houston
- Fairmont Hotels in Houston
- Waterpark Hotels in Houston
- Hotels near Toyota Center
- Houston Hotels
- Pet-Friendly Hotels in Houston
- Hotels with Free Airport Shuttle in Houston
- Hotels with Balconies in Houston
- Flights from Winnipeg (YWG) to Houston (IAH)
- Flights from George Bush Intercontinental
- Flights from New Orleans (MSY) to Houston (HOU)
- Flights from Ottawa (YOW) to Houston (HOU)
- Flights from Calgary (YYC) to Houston (IAH)
- Flights from Montreal (YUL) to Houston (HOU)
- Flights from Seattle (SEA) to Houston (IAH)
- Flights from Vancouver (YVR) to Houston (IAH)
- Flights from Saskatoon (YXE) to Houston (IAH)
- Flights from Toronto (YYZ) to Houston (IAH)
- Flights from Detroit (DTW) to Houston (IAH)
- Flights from Atlanta (ATL) to Houston (HOU)
- Flights from Ottawa (YOW) to Houston (IAH)
- Flights from Calgary (YYC) to Houston (HOU)
- Flights from Houston
- Flights from Buffalo (BUF) to Houston (HOU)
- Flights from Edmonton (YEG) to Houston (IAH)
- Flights from Chicago (ORD) to Houston (HOU)
- Flights from Dallas (DFW) to Houston (HOU)
- Flights from Halifax (YHZ) to Houston (IAH)
- Flights from Toronto (YYZ) to Houston (HOU)
- Flights from Winnipeg (YWG) to Houston (HOU)
- Flights from Edmonton (YEG) to Houston (HOU)
- Flights from William P. Hobby
- Flights from New York (JFK) to Houston (HOU)
- Flights from Kelowna (YLW) to Houston (HOU)
- Flights from Vancouver (YVR) to Houston (HOU)
- Flights from Montreal (YUL) to Houston (IAH)
- Flights to Houston
- Visit Crash Boat Basin
- Houston Museum of Fine Arts
- Visit Brookshire
- Visit Second Ward
- Visit Bammel
- Visit Midtown
- Houston Vacations
- Discovery Green
- Porter Vacations
- Visit The Galleria
- Hermann Park
- Visit Cypress
- Visit Houston Central Business District
- Downtown Aquarium
- Visit Lake Olympia
- Visit Montrose
- Visit Texas Medical Center
- Visit Riverstone
- Visit Galveston
- Visit Greater Greenspoint
- Visit Nassau Bay
- Visit Houston
- Visit League City
- Visit Bellaire
- Visit Greater Third Ward
- Visit Downtown Houston
- Visit Katy
- Visit Tiki Island
- Visit Astrodome
- Visit Pirates Beach
- Visit Jamaica Beach
- Visit Westchase
- Visit Piney Point Village
- Visit Ponderosa Forest
- Visit Alden Bridge
- Visit Houston Heights
