Eastern Region Vacation Rentals from CA $52: Short-Term Rentals for 2026

A large steel bridge spanning a river with dense greenery and a small island with vegetation in the foreground.

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Top Cities in Eastern Region

A dense palm tree line, a road, and a distant view of a town with buildings and a transmission tower.

A collection of colorful, intricately decorated beads.

Our top choices for Eastern Region vacation rentals

A modern living room with a flat-screen TV, comfortable seating, and a decorative wall piece.

1. ESPADA LODGE Studio 3.3

Somanya

CA $54 total

includes taxes & fees

Oct 20 - Oct 21

A nighttime view of a bridge with a metal railing, leading to a grassy area with trees and a swing set.

2. GENK FARMHOUSE

Adawso

CA $212 total

includes taxes & fees

Oct 26 - Oct 27

A bedroom with a wooden bed, a desk with a chair, a potted plant, and a sliding door leading to a balcony.

3. The Treehouse Studio apartments with a large rooftop terrace.

Aburi-South

Emmanuel M.

CA $164 total

includes taxes & fees

Oct 20 - Oct 21

A courtyard with stone flooring, potted plants, and a view of distant buildings under a cloudy sky.

4. Hillside Gardens, Aburi:Luxury Living & Breathtaking Views in a Peaceful Climate

Aburi

CA $303 total

includes taxes & fees

Oct 20 - Oct 21

A two-story house with a brick exterior, a balcony, and a gated entrance.

5. Cozy Bricks Apartment

Obomeng

CA $92 total

includes taxes & fees

Oct 20 - Oct 21

A living room with a sofa, a coffee table, and a potted plant.

6. Santa Monica Home Lodge - Unit #001

New Akrade

CA $272 total

includes taxes & fees

Oct 20 - Oct 21

A paved driveway leading to a building, surrounded by greenery and palm trees.

7. Oaks : Private Room 9

Nkawkaw , Kwahu

CA $88 total

includes taxes & fees

Oct 20 - Oct 21

A hallway with patterned pillars, a metal railing, and large cacti.

8. Oaks : Private Room 4

Nkawkaw

CA $110 total

includes taxes & fees

Oct 20 - Oct 21

A hotel room with a brick wall, a bed with white bedding, two pillows, a nightstand with a lamp, and a painting of a traditional scene.

9. Santa Monica Home Lodge

New Akrade

CA $345 total

includes taxes & fees

Oct 20 - Oct 21

A living room with a sofa, two armchairs, a coffee table, and a ceiling fan.

10. Sanga Estates Luxury Apartments

Accra

Salma

CA $52 total

includes taxes & fees

Oct 20 - Oct 21

A bathroom with a shower, a glass door, and a window with blinds.

11. Jannah Villas - Ghana

Adentan

Aderemi

CA $89 total

includes taxes & fees

Oct 26 - Oct 27

A compact kitchen with a built-in microwave, a sink, and a wooden countertop.

12. Mayama Residences

Accra

Magaji

CA $73 total

includes taxes & fees

Nov 2 - Nov 3

A modern residential building with a courtyard, featuring a mix of brick and plaster walls, multiple balconies, and a gravel driveway.

13. Espada Lodge Apartmento

Amrahia

CA $45 total

includes taxes & fees

Oct 28 - Oct 29

A bedroom with a bed, a nightstand, a window with blinds, and a colorful ceiling.

14. Cherry Signature Condos

Adenta Municipality

CA $106 total

includes taxes & fees

Oct 21 - Oct 22

A hotel room with a bed, two bedside lamps, a nightstand, a chair, and a patterned floor.

15. CK Suites

Adentan

Tyson

CA $86 total

includes taxes & fees

Oct 20 - Oct 21

A gym with a rack of dumbbells and a weight bench.

16. Peravi at The Signature

Accra

Rose

CA $116 total

includes taxes & fees

Oct 28 - Oct 29

A multi-story building with balconies and a gated entrance.

17. Washington Court Apartments

Accra

Tiera

CA $106 total

includes taxes & fees

Oct 20 - Oct 21

A hotel with outdoor seating and a well-maintained lawn.

18. Alexander Palace Hotel Apartment

Amrahia

Vera

CA $163 total

includes taxes & fees

Oct 21 - Oct 22

A balcony with a view of palm trees and a road, furnished with a table and chairs, and potted plants.

19. The Peppy Hotel

Labadi

CA $104 total

includes taxes & fees

Oct 21 - Oct 22

A multi-story residential building with balconies, a central courtyard, and a flat roof.

20. High Level Apartment

Accra

Albert

CA $65 total

includes taxes & fees

Oct 26 - Oct 27

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Top Eastern Region Hotel Reviews

Airport View Hotel

8/10 Good

"I have stayed here for the past 5 to 6 years and there has been a lot of improvement. From reception to cleaning. I didn't go to the restaurant this time ,so I can't say much about that but room service was good. Food has improved . My only downside was the water wasn't warm enough for showers and restaurant need a little more improvement with their burgers. Comparing the past which was always 6,I will give them a 9/10 this time. Am happy they listen to reviews. See you all soon."

The African Regent Hotel

10/10 Excellent

"I really enjoyed staying at the African Regent Hotel in Accra, Ghana. It was enchanting to walk into the very African themed lobby to hear piano music playing. And that was just the start of a wonderful week staying there. The breakfast, although not very varied from day-to-day, filled me up and got me ready for full days of touring. I used the pool and the loungers and was very satisfied with them. I happened to catch a cold just as I arrived, and I tell you, it was the most wonderfully comfortable bed to rest in for a day or two before I felt better. The staff were incredibly helpful all the way through, and they are very nice and welcoming. The rooms are well thought out and fully equipped. Even the bar is really pretty! I would definitely stay there again."

La Palm Royal Beach Hotel

8/10 Good

"I really enjoyed this hotel. It's a little run down from it's former glory...but the staff are genuinely welcoming. From the first contact to the last. Pool is nice. Gym is fine, except non of the weights are particularly heavy. Juliette on reception was excellent. And please try the goat light red soup...it was excellent."

Find out more about Eastern Region

Everything you need to know about Eastern Region vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Eastern Region vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Eastern Region vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Eastern Region vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Eastern Region. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Eastern Region vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Eastern Region vacation rentals we have selected for you start as low as CA $52 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Eastern Region rentals

At Expedia, we put the best Eastern Region vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Eastern Region rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Eastern Region vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Eastern Region. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Room 1

Change your mind

Treat yourself

Be picky

Top Cities in Eastern Region

Aburi

Koforidua

Our top choices for Eastern Region vacation rentals

1. ESPADA LODGE Studio 3.3

2. GENK FARMHOUSE

3. The Treehouse Studio apartments with a large rooftop terrace.

4. Hillside Gardens, Aburi:Luxury Living & Breathtaking Views in a Peaceful Climate

5. Cozy Bricks Apartment

6. Santa Monica Home Lodge - Unit #001

7. Oaks : Private Room 9

8. Oaks : Private Room 4

9. Santa Monica Home Lodge

10. Sanga Estates Luxury Apartments

11. Jannah Villas - Ghana

12. Mayama Residences

13. Espada Lodge Apartmento

14. Cherry Signature Condos

15. CK Suites

16. Peravi at The Signature

17. Washington Court Apartments

18. Alexander Palace Hotel Apartment

19. The Peppy Hotel

20. High Level Apartment

Find vacation rentals that suit your style

Top Eastern Region Hotel Reviews

Airport View Hotel

Kempinski Hotel Gold Coast City

Accra Luxury Apartments at The Gallery

The Pelican Hotel Cantonments Accra

Accra Luxury Apartments At The Signature

The African Regent Hotel

Mövenpick Ambassador Hotel Accra

The Royal Senchi Hotel and Resort

La Palm Royal Beach Hotel

Find out more about Eastern Region