Title: Book The Best Hotels in Clarksdale, MO for 2026 from CA $90 - Fully Refundable Options - Expedia.ca [Clarksdale Travel Guide](https://expedia.ca/Clarksdale.dx553248634983445286)[Vacation Rentals in Clarksdale](https://expedia.ca/Clarksdale-Vacation-Rentals.d553248634983445286.Travel-Guide-VacationRentals)[Clarksdale Car Rentals](https://expedia.ca/Car-Rentals-In-Clarksdale.d553248634983445286.Car-Rental-Guide)[Clarksdale Vacation Packages](https://expedia.ca/Clarksdale.d553248634983445286.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Clarksdale Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-03-16&d1=2026-03-16&endDate=2026-03-18&d2=2026-03-18&travelerType=family_friendly) Pool [](https://www.expedia.ca/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-03-16&d1=2026-03-16&endDate=2026-03-18&d2=2026-03-18&amenities=POOL) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-03-16&d1=2026-03-16&endDate=2026-03-18&d2=2026-03-18&amenities=PETS) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-03-16&d1=2026-03-16&endDate=2026-03-18&d2=2026-03-18&amenities=HOT_TUB) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Clarksdale%2C+Missouri%2C+United+States+of+America®ionId=553248634983445286&latLong=39.813608%2C-94.550512&adults=2&startDate=2026-03-16&d1=2026-03-16&endDate=2026-03-18&d2=2026-03-18&lodging=APARTMENT) ## Check prices for these dates Tonight [Mar 2 - Mar 3](https://www.expedia.ca/Hotel-Search?regionId=553248634983445286&startDate=2026-03-02&endDate=2026-03-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 3 - Mar 4](https://www.expedia.ca/Hotel-Search?regionId=553248634983445286&startDate=2026-03-03&endDate=2026-03-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 6 - Mar 8](https://www.expedia.ca/Hotel-Search?regionId=553248634983445286&startDate=2026-03-06&endDate=2026-03-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=553248634983445286&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Clarksdale hotels ![Front of property](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/86578d4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/e03c581b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/f4c6728d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/19000000/18840000/18838600/18838527/f76ef679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Vineyard Mansion & Carriage House Bed & Breakfast [](https://www.expedia.ca/St-Joseph-Hotels-Vineyard-Mansion-Carriage-House-Bed-Breakfast.h18838527.Hotel-Information) St. Joseph 9.0/10 Wonderful (200 reviews) "Enjoyed our stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vincent CA $146 CA $215 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/St-Joseph-Hotels-Vineyard-Mansion-Carriage-House-Bed-Breakfast.h18838527.Hotel-Information) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/33a09121.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, pillowtop beds, desk, laptop workspace](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/29a35617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, stovetop, coffee/tea maker](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/w3000h1897x0y3-644920c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### My Place Hotel St Joseph MO [](https://www.expedia.ca/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) St. Joseph 9.2/10 Wonderful (220 reviews) "It was a clean place to stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ayden CA $101 CA $116 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/bd099a64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/cffb314f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Miscellaneous](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/c9cd0093.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/w1000h963x0y0-b16dd7a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Whiskey Mansion [](https://www.expedia.ca/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information) St. Joseph 9.2/10 Wonderful (589 reviews) "Bueatiful home, clean, quiet and fantastic service and food!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ellie CA $185 CA $215 total includes taxes & fees Mar 12 - Mar 13 [](https://www.expedia.ca/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information) ![Premium bedding, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/9d51d430.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![32-inch flat-screen TV with cable channels, TV](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/b3fa2b58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/10d352cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/6685816e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmeriStay Inn [](https://www.expedia.ca/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information) St. Joseph 5.4/10 (711 reviews) "Always friendly staff and clean quiet rooms" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jacob [](https://www.expedia.ca/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/574523e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free WiFi](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/30b33635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites By Hilton St. Joseph [](https://www.expedia.ca/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information) St. Joseph 9.4/10 Exceptional (103 reviews) "Great stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marcella M CA $144 CA $167 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/8955ad72.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/71deeec7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/55bf67a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites St. Joseph by IHG [](https://www.expedia.ca/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information) St. Joseph 9.2/10 Wonderful (810 reviews) "Breakfast was good, nice selection of food, Front desk staff were courteous and helpful, cleaning ladies were helpful, room was adequate, nice location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim CA $138 CA $159 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information) ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/56e589c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/f99f9ca0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/eb107eed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/d7bb37bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Saint Joseph, MO [](https://www.expedia.ca/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information) St. Joseph 4.6/10 (1,001 reviews) "Staff was very nice, very clean, pet friendly. Will definitely stay here again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda CA $103 CA $119 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/b42a1684.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/f5217c79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/e0d9868d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/7977062c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott St. Joseph [](https://www.expedia.ca/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information) St. Joseph 9.6/10 Exceptional (479 reviews) "Clean room and friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jerome CA $131 CA $153 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Snack bar](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/d2e48a08.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8254b815.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/923f99c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn St. Joseph [](https://www.expedia.ca/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information) St. Joseph 8.2/10 Very good (669 reviews) "A great place to stay-clean and friendly staff!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jason CA $108 CA $125 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/82c1711e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/2de574ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/64e61c4d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Single Room, 1 King Bed with Sofa bed, Hot Tub](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/a2c57571.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stoney Creek Hotel St. Joseph [](https://www.expedia.ca/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information) St. Joseph 9.0/10 Wonderful (1,606 reviews) "Always enjoy staying here . Staff was awesome 👍" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) evvamae CA $152 CA $176 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/cdd2480a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/602776a9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/w3000h2001x0y1-908111e6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/42200/42165/9fa0a9ca.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Cameron [](https://www.expedia.ca/St-Joseph-Hotels-Days-Inn-By-Wyndham-Cameron.h42165.Hotel-Information) Cameron 7.6/10 Good (842 reviews) "Easy to locate, quiet, room was clean, breakfast was OK" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Vicki CA $90 CA $99 total includes taxes & fees Apr 1 - Apr 2 [](https://www.expedia.ca/St-Joseph-Hotels-Days-Inn-By-Wyndham-Cameron.h42165.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 2 Queen Beds (Smoke Free)](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/538cff90.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 Queen Bed, Accessible (Smoke Free)](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/65cb8e48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/cc53b139.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Red Roof Inn Cameron [](https://www.expedia.ca/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information) Cameron 8.8/10 Excellent (1,003 reviews) "Clean room and friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jessica [](https://www.expedia.ca/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/ea88e07b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/80e80506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/33a59e94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free breakfast](https://images.trvl-media.com/lodging/1000000/20000/10500/10417/60106125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SureStay Hotel by Best Western Cameron [](https://www.expedia.ca/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information) Cameron 8.2/10 Very good (1,000 reviews) "Good one night stay experience " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) LIQIANG CA $95 CA $105 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/Cameron-Hotels-SureStay-Hotel-By-Best-Western-Cameron.h10417.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/d2b9e218.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 2 Queen Beds, Accessible (Sofa Sleeper, Roll-in Shower, 2 Rooms)](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/97fa97c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/ce15b185.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/15777d71.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites St Joseph [](https://www.expedia.ca/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information) St. Joseph 9.4/10 Exceptional (1,002 reviews) "Amazing friendly staff, clean rooms, bathroom was spotless. Enjoyed my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Aaron CA $136 CA $158 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information) ![Pool](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/85cb1016.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/965f4dc2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/a59c6aa9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/28b1385b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Cameron [](https://www.expedia.ca/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information) Cameron 8.4/10 Very good (635 reviews) "Surprisingly quite next to the interstate. Older hotel, but still has some charm. Breakfast, customer service and the rooms were nice. My family and I enjoyed our stay." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly CA $146 CA $163 total includes taxes & fees Apr 2 - Apr 3 [](https://www.expedia.ca/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information) ![Room, 1 King Bed, Hot Tub](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fbe988e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/2c2d2265.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free cribs/infant beds](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/3d5ca308.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/d3b97e86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Cameron [](https://www.expedia.ca/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information) Cameron 8.4/10 Very good (648 reviews) "Very clean and friendly staff. Nice place!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dean CA $103 CA $113 total includes taxes & fees Mar 13 - Mar 14 [](https://www.expedia.ca/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/683baa8a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free cribs/infant beds, rollaway beds, free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/f60992f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/7ac0c126.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Smoking, Ground Floor](https://images.trvl-media.com/lodging/1000000/180000/171700/171630/65898125.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Econo Lodge Cameron [](https://www.expedia.ca/St-Joseph-Hotels-Econo-Lodge-Cameron.h171630.Hotel-Information) Cameron 6.2/10 (162 reviews) "Lovely staff. Very helpful" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Colleen CA $93 CA $102 total includes taxes & fees Mar 8 - Mar 9 [](https://www.expedia.ca/St-Joseph-Hotels-Econo-Lodge-Cameron.h171630.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/c6efac2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room amenity](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/79d2554d_edited_dfdc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/3cfc730e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee and/or coffee maker](https://images.trvl-media.com/lodging/10000000/10000000/9992800/9992788/96bdd18f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Cameron, MO [](https://www.expedia.ca/Cameron-Hotels-Motel-6-Cameron.h9992788.Hotel-Information) Cameron 7.0/10 Good (296 reviews) "Very clean and comfortable. Great staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph CA $81 CA $90 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Cameron-Hotels-Motel-6-Cameron.h9992788.Hotel-Information) ![Deluxe Apartment, 3 Bedrooms, Park View | Park view](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/f105b4ea.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 3 Bedrooms, Park View | Living area](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/e4bcc2ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 3 Bedrooms, Park View](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/f2b04a15.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Apartment, 3 Bedrooms, Park View](https://images.trvl-media.com/lodging/75000000/74710000/74704700/74704690/w4032h2718x0y306-05e60f43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cameron Suites [](https://www.expedia.ca/Cameron-Hotels-Cameron-Suites.h74704690.Hotel-Information) Cameron CA $150 CA $301 total includes taxes & fees Mar 3 - Mar 4 [](https://www.expedia.ca/Cameron-Hotels-Cameron-Suites.h74704690.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-16&endDate=2026-03-17®ionId=553248634983445286&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=HTG_SPRING_PROMO_553248634983445286) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FClarksdale-Hotels.d553248634983445286.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FClarksdale-Hotels.d553248634983445286.Travel-Guide-Hotels) ## Top Clarksdale Hotel Reviews ## Recent Reviews in Clarksdale ![Drury Inn & Suites St Joseph](https://images.trvl-media.com/lodging/1000000/10000/4200/4180/2dd83c29_y.jpg) ### Drury Inn & Suites St Joseph 10/10 Excellent "Courtesy, clean room, quiet, comfortable, safe and great food!" [](https://expedia.ca/St-Joseph-Hotels-Drury-Inn-Suites-St-Joseph.h4180.Hotel-Information) ![Holiday Inn Express Hotel & Suites St. Joseph by IHG](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb_y.jpg) ### Holiday Inn Express Hotel & Suites St. Joseph by IHG 10/10 Excellent "Had a pleasant stay. Room and people were nice. Loved the coffee." [](https://expedia.ca/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information) ![Stoney Creek Hotel St. Joseph](https://images.trvl-media.com/lodging/2000000/1140000/1140000/1139931/342fa799_y.jpg) ### Stoney Creek Hotel St. Joseph 10/10 Excellent "Staff was great. Place was a cut above typical hotel. Nice motif. Spotless. Good breakfast offerings..." [](https://expedia.ca/St-Joseph-Hotels-Stoney-Creek-Hotel-St-Joseph.h1139931.Hotel-Information) ![Home2 Suites By Hilton St. Joseph](https://images.trvl-media.com/lodging/115000000/114260000/114252400/114252394/30b33635_y.jpg) ### Home2 Suites By Hilton St. Joseph 10/10 Excellent "Everything is always perfect when we stay here. Always clean! The room is perfect it’s really like home away. " [](https://expedia.ca/St-Joseph-Hotels-Home2-Suites-By-Hilton-St-Joseph.h114252394.Hotel-Information) ![Super 8 by Wyndham Cameron](https://images.trvl-media.com/lodging/1000000/860000/855500/855452/fbe988e4_y.jpg) ### Super 8 by Wyndham Cameron 10/10 Excellent "Staff was really nice and friendly." [](https://expedia.ca/St-Joseph-Hotels-Super-8-By-Wyndham-Cameron.h855452.Hotel-Information) ![My Place Hotel St Joseph MO](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0_y.jpg) ### My Place Hotel St Joseph MO 10/10 Excellent "Very nice hotel, clean and efficient staff." [](https://expedia.ca/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) ![Fairfield Inn & Suites by Marriott St. Joseph](https://images.trvl-media.com/lodging/19000000/18180000/18179000/18178902/b42a1684_y.jpg) ### Fairfield Inn & Suites by Marriott St. Joseph 10/10 Excellent "As great" [](https://expedia.ca/St-Joseph-Hotels-Fairfield-Inn-Suites-By-Marriott-St-Joseph.h18178902.Hotel-Information) ![Whiskey Mansion](https://images.trvl-media.com/lodging/5000000/4220000/4214600/4214555/81b46103_y.jpg) ### Whiskey Mansion 10/10 Excellent "Holly was a wonderful host for our stay!! Breakfasts felt so fancy and made with love, definitely coming back again! The decor and vibe of the place was so beautiful :)" [](https://expedia.ca/St-Joseph-Hotels-Whiskey-Mansion.h4214555.Hotel-Information) ![Quality Inn Cameron](https://images.trvl-media.com/lodging/1000000/50000/42200/42192/5baaa282_y.jpg) ### Quality Inn Cameron 10/10 Excellent "Yes" [](https://expedia.ca/St-Joseph-Hotels-Quality-Inn-Cameron.h42192.Hotel-Information) ## More cheap stays in Clarksdale ![My Place Hotel St Joseph MO](https://images.trvl-media.com/lodging/110000000/109470000/109463300/109463264/aa4717a0_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### My Place Hotel St Joseph MO 3621 N Village Dr St. Joseph MO CA $101 CA $116 total Mar 8 - Mar 9 includes taxes & fees 9.2/10 Wonderful! (220 reviews) [](https://expedia.ca/St-Joseph-Hotels-My-Place-Hotel-St-Joesph-MO.h109463264.Hotel-Information) ![Motel 6 Saint Joseph, MO](https://images.trvl-media.com/lodging/1000000/50000/49600/49581/771cfdad_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Motel 6 Saint Joseph, MO 4021 Frederick Ave St. Joseph MO CA $103 CA $119 total Mar 3 - Mar 4 includes taxes & fees 4.6/10 (1,001 reviews) [](https://expedia.ca/St-Joseph-Hotels-Motel-6-Saint-Joseph.h49581.Hotel-Information) ![Hampton Inn St. Joseph](https://images.trvl-media.com/lodging/1000000/110000/103100/103092/8e39c5c8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hampton Inn St. Joseph 3928 Frederick Ave St. Joseph MO CA $108 CA $125 total Mar 8 - Mar 9 includes taxes & fees [](https://expedia.ca/St-Joseph-Hotels-Hampton-Inn-St-Joseph.h103092.Hotel-Information) ![Holiday Inn Express Hotel & Suites St. Joseph by IHG](https://images.trvl-media.com/lodging/7000000/6850000/6846800/6846757/47ec36cb_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Holiday Inn Express Hotel & Suites St. Joseph by IHG 3600 N. Village Dr. St. Joseph MO CA $138 CA $159 total Mar 8 - Mar 9 includes taxes & fees 9.2/10 Wonderful! (810 reviews) [](https://expedia.ca/St-Joseph-Hotels-Holiday-Inn-Express-Hotel-Suites-St-Joseph.h6846757.Hotel-Information) ![AmeriStay Inn](https://images.trvl-media.com/lodging/1000000/50000/41500/41477/8f84e3de_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### AmeriStay Inn 4502 SE US HWY 169 St. Joseph MO [Get rates](https://expedia.ca/Hotel-Search?startDate=16%2F03%2F2026&endDate=17%2F03%2F2026&selected=41477&PinnedHotelID=41477&HadPinnedHotel=true®ionId=553248634983445286) 5.4/10 (711 reviews) [](https://expedia.ca/St-Joseph-Hotels-AmeriStay-Inn.h41477.Hotel-Information) ![Red Roof Inn Cameron](https://images.trvl-media.com/lodging/1000000/40000/40000/39991/917e85d1_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Red Roof Inn Cameron 501 Northland Drive Cameron MO [Get rates](https://expedia.ca/Hotel-Search?startDate=16%2F03%2F2026&endDate=17%2F03%2F2026&selected=39991&PinnedHotelID=39991&HadPinnedHotel=true®ionId=553248634983445286) 8.8/10 Excellent! (1,003 reviews) [](https://expedia.ca/St-Joseph-Hotels-Red-Roof-Inn-Cameron.h39991.Hotel-Information) ## Hotels in Clarksdale with star rating ![3 Star Hotels](https://images.trvl-media.com/lodging/20000000/19690000/19681400/19681371/84fffc75_z.jpg) 3 Star Hotels 6 properties [](https://expedia.ca/3Star-Clarksdale-Hotels.s30-0-d553248634983445286.Travel-Guide-Filter-Hotels) ![2 Star Hotels](https://images.trvl-media.com/lodging/92000000/91830000/91828000/91827910/6717a2ac_z.jpg) 2 Star Hotels 27 properties [](https://expedia.ca/2Star-Clarksdale-Hotels.s20-0-d553248634983445286.Travel-Guide-Filter-Hotels) ## Frequently asked questions ### When is the best time to go to Clarksdale? > During these months, you'll find comfortable temperatures, ideal for walking around and enjoying outdoor music. The humidity is lower than in the summer, making it much more agreeable for sightseeing and attending events. Many of the local festivals, celebrating blues music and culture, are scheduled during these periods, offering a rich experience for visitors keen on the local heritage. > > > Summer in Clarksdale (June to August) can be very hot and humid, with temperatures often soaring. While there are still events and music, the extreme heat might make extended outdoor activities less enjoyable. However, if you're primarily focused on indoor attractions like the Delta Blues Museum and various juke joints, and don't mind the heat, summer can still be a good time to visit. > > > Winter (November to March) is generally cooler and quieter. While you'll still find live music, some venues might have reduced schedules, and the overall pace is slower. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a Clarksdale hotel booking with Expedia? ### How much is the nightly rate at a Clarksdale hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [5 Star Hotels in Cameron ](https://www.expedia.ca/5Star-Cameron-Hotels.s50-0-d6533.Travel-Guide-Filter-Hotels) - [Condo Rentals in Agency ](https://www.expedia.ca/Agency-Condos.d553248634983462091-aaCondos.Travel-Guide-Accommodation) - [Agency Hotels ](https://www.expedia.ca/Agency-Hotels.d553248634983462091.Travel-Guide-Hotels) - [Luxury Hotels in Amazonia ](https://www.expedia.ca/Amazonia-Hotels-Luxury-Hotel.0-0-d3000349270-tLuxuryHotel.Travel-Guide-Filter-Hotels) - [Amazonia Hotels ](https://www.expedia.ca/Amazonia-Hotels.d3000349270.Travel-Guide-Hotels) - [Amity Hotels ](https://www.expedia.ca/Amity-Hotels.d553248634983263244.Travel-Guide-Hotels) - 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