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Cherokee Vacation Rentals

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Our top choices for Cherokee vacation rentals

1. The 72 Rendezvous

The 72 Rendezvous
Cherokee
The price is CA $187
CA $403 total
includes taxes & fees
Sep 13 - Sep 14
The 72 Rendezvous

2. Perfect lake front cottage! Now with stairs to the water!

Perfect lake front cottage! Now with stairs to the water!
Waterloo
9.8 out of 10, Exceptional, (129 reviews)
"Wonderful stay! Great views at a cozy cabin!"
United States
Andrew A.
The price is CA $274
CA $505 total
includes taxes & fees
Sep 2 - Sep 3
Perfect lake front cottage! Now with stairs to the water!

3. Iuka Historic Downtown King Loft C

Iuka Historic Downtown King Loft C
Iuka
10.0 out of 10, Exceptional, (5 reviews)
"Wonderful place to stay"
United States
Sherry B.
The price is CA $159
CA $317 total
includes taxes & fees
Sep 2 - Sep 3
Iuka Historic Downtown King Loft C

4. Country Bliss

Country Bliss
Tishomingo
10.0 out of 10, Exceptional, (25 reviews)
"Love this place"
United States
Randall S.
The price is CA $123
CA $236 total
includes taxes & fees
Sep 9 - Sep 10
Country Bliss

5. Fern Hollow Treehouse, rustic escape cozy romantic

Fern Hollow Treehouse, rustic escape cozy romantic
Tishomingo
9.8 out of 10, Exceptional, (42 reviews)
"Beautiful and unique place to stay! The outdoor bathhouse was a great way to cool off from the humidity! Bring your mosquito repellent!!"
United States
Mel L.
The price is CA $242
CA $378 total
includes taxes & fees
Sep 13 - Sep 14
Fern Hollow Treehouse, rustic escape cozy romantic

6. Stenson Hollow Lake Condo

Stenson Hollow Lake Condo
Muscle Shoals
9.6 out of 10, Exceptional, (111 reviews)
"The view of the lake was nice and we enjoyed seeing the fireflies at night"
United States
Wayne
The price is CA $118
CA $273 total
includes taxes & fees
Sep 9 - Sep 10
Stenson Hollow Lake Condo

7. The Gypsy Queen

The Gypsy Queen
Tishomingo
9.4 out of 10, Exceptional, (3 reviews)
"It was amaIng"
United States
Jack
The price is CA $173
CA $302 total
includes taxes & fees
Sep 6 - Sep 7
The Gypsy Queen

8. 3-bedroom w/pool and all the comforts of home in Muscle Shoals-recording capital

3-bedroom w/pool and all the comforts of home in Muscle Shoals-recording capital
Muscle Shoals
9.6 out of 10, Exceptional, (71 reviews)
"We had a wonderful time at this lovely home. The pool was amazing."
United States
Tim c.
The price is CA $166
CA $467 total
includes taxes & fees
Sep 2 - Sep 3
3-bedroom w/pool and all the comforts of home in Muscle Shoals-recording capital

9. "Cottage @ JP Coleman"-perfect getaway at Pickwick

"Cottage @ JP Coleman"-perfect getaway at Pickwick
Iuka
9.6 out of 10, Exceptional, (46 reviews)
"Clean, decorated well, with well stocked items for hygiene, if you forgot something, nice size and excellent communication. Highly recommend. "
United States
Charles B.
The price is CA $166
CA $348 total
includes taxes & fees
Sep 2 - Sep 3
"Cottage @ JP Coleman"-perfect getaway at Pickwick

10. Romantic Cozy Cottage 0.8 miles from JP Coleman State Park / Pickwick / Iuka

Romantic Cozy Cottage 0.8 miles from JP Coleman State Park / Pickwick / Iuka
Iuka
10.0 out of 10, Exceptional, (2 reviews)
"Super cute tiny home and really close to JP Coleman boat ramp. I would stay again and again!"
United States
EMILY B.
The price is CA $159
CA $259 total
includes taxes & fees
Sep 8 - Sep 9
Romantic Cozy Cottage 0.8 miles from JP Coleman State Park / Pickwick / Iuka

11. The Loft on Main

The Loft on Main
Belmont
9.8 out of 10, Exceptional, (19 reviews)
"Can't say enough good things about this place.... LOVED IT!!"
United States
Mark
The price is CA $137
CA $251 total
includes taxes & fees
Sep 15 - Sep 16
The Loft on Main

12. McCrary Clan Lodge

McCrary Clan Lodge
Counce
10.0 out of 10, Exceptional, (111 reviews)
"This house was super nice and just as described. 10/10 would stay here again. "
United States
Melissa R.
The price is CA $111
CA $274 total
includes taxes & fees
Sep 2 - Sep 3
McCrary Clan Lodge

13. Summer Openings! Perfect spot on lake for fishing! Spacious home & backyard

Summer Openings! Perfect spot on lake for fishing! Spacious home & backyard
Iuka
9.8 out of 10, Exceptional, (57 reviews)
"Second time staying at this house. Great house, great location, great hosts. "
United States
Robert W.
The price is CA $187
CA $396 total
includes taxes & fees
Sep 8 - Sep 9
Summer Openings! Perfect spot on lake for fishing! Spacious home & backyard

14. Charming 2-bedroom house with AC, WiFi in wonderful Florence

Charming 2-bedroom house with AC, WiFi in wonderful Florence
Florence
8.8 out of 10, Excellent, (6 reviews)
"Adorable house, great location, awesome host, very comfortable "
United States
Jamie S.
The price is CA $94
CA $405 total
includes taxes & fees
Sep 2 - Sep 3
Charming 2-bedroom house with AC, WiFi in wonderful Florence

15. Emerald Hour Loft: 2 mins from UNA

Emerald Hour Loft: 2 mins from UNA
Florence
9.6 out of 10, Exceptional, (5 reviews)
"Perfect location and great Accommodations. Host was easy to contact and plan to stay again if available. ."
United States
Andrea
The price is CA $151
CA $308 total
includes taxes & fees
Sep 2 - Sep 3
Emerald Hour Loft: 2 mins from UNA

16. Crossroads to Pickwick Cabin SMOOTH SAILING

Crossroads to Pickwick Cabin SMOOTH SAILING
Iuka
9.8 out of 10, Exceptional, (27 reviews)
"The property was very clean and located perfectly between JP Coleman State Park and Sportmans at the TN Line. Great spot will stay there again."
United States
John B.
The price is CA $198
CA $306 total
includes taxes & fees
Sep 8 - Sep 9
Crossroads to Pickwick Cabin SMOOTH SAILING

17. A little piece of Heaven

A little piece of Heaven
Muscle Shoals
9.6 out of 10, Exceptional, (49 reviews)
"Very clean with a great view of the water. Great place for a short stay. "
United States
Tracy P.
The price is CA $128
CA $330 total
includes taxes & fees
Sep 2 - Sep 3
A little piece of Heaven

18. ReNew At JW's & bring your Dog too!

ReNew At JW's & bring your Dog too!
East Florence
9.4 out of 10, Exceptional, (13 reviews)
"The house is laid out very well, and the neighborhood is close to everything and quiet at night. The fenced yard was perfect for the pups. We would stay here again."
United Kingdom
Nicole L.
The price is CA $106
CA $253 total
includes taxes & fees
Sep 2 - Sep 3
ReNew At JW's & bring your Dog too!

19. Lagniappe in Florence

Lagniappe in Florence
Florence
10.0 out of 10, Exceptional, (51 reviews)
"A wonderful spot for a weekend getaway! Loved staying here!"
United States
addie s.
The price is CA $236
CA $474 total
includes taxes & fees
Sep 2 - Sep 3
Lagniappe in Florence

20. Cowboy Cottage

Cowboy Cottage
Florence
10.0 out of 10, Exceptional, (28 reviews)
"Peaceful, immaculate and dog friendly!"
United States
Tanya N.
The price is CA $132
CA $235 total
includes taxes & fees
Sep 8 - Sep 9
Cowboy Cottage
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Cherokee Hotel Reviews

Find out more about Cherokee

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Cherokee. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Can I find vacation rentals in Cherokee?

Yes, you can find vacation rentals near popular points of interest in Cherokee, or you can select a secluded option if you're looking for a relaxing stay.

What are some of the best vacation rentals in Cherokee?

Rustic Cabin overlooking Pickwick Lake: This Cherokee vacation home rental is located on a lake and offers a barbecue grill, air-conditioning, and laundry facilities to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave. Our travelers also rate RIVERTON LAKESIDE COTTAGE ON PICKWICK LAKE as a favorite home for rent in Cherokee.

How many vacation rentals are there in Cherokee?

Choose from 7 Expedia vacation rentals in Cherokee for a memorable vacation.

What can I see and do in Cherokee?

Pickwick Lake and Tennessee River are a couple of lovely local spots to get outside and enjoy nature. Cane Creek Canyon Nature Preserve and Ivy Green are a couple of places you'll find in the larger area.

What are vacation rentals like in Cherokee?

Vacation rentals are privately owned accommodations you can reserve for several days or longer in Cherokee. Vacation rentals offer amenities like WiFi and washers and dryers so you'll have a home away from home. If you're concerned about a sanitized environment, a vacation rental can provide a sense of safety away from public hotel elevators and busy reception areas while still allowing you the excitement and enjoyment of travel. You'll also find more space in a vacation rental than in a standard hotel, which is another reason why a vacation rental is an attractive option for family trips.