Title: The 10 Best Hotels Near UCSF Mission Bay, San Francisco from CA $138 | Expedia.ca

 

[Downtown San Francisco Travel Guide](https://expedia.ca/San-Francisco-Downtown-San-Francisco.dx6151902)[UCSF Mission Bay Car Rentals](https://expedia.ca/Car-Rentals-In-UCSF-Mission-Bay.d553248635389801411.Car-Rental-Guide)[UCSF Mission Bay Vacations](https://expedia.ca/UCSF-Mission-Bay-Downtown-San-Francisco.d553248635389801411.Vacation-Attraction)

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Photo by Rebecca Friedland

# Find hotels near UCSF Mission Bay, San Francisco from CA $138

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## Check prices for these dates

Tonight

[Nov 28 - Nov 29](https://www.expedia.ca/Hotel-Search?regionId=553248635389801411&startDate=2025-11-28&endDate=2025-11-29&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Tomorrow

[Nov 29 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248635389801411&startDate=2025-11-29&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

This weekend

[Nov 28 - Nov 30](https://www.expedia.ca/Hotel-Search?regionId=553248635389801411&startDate=2025-11-28&endDate=2025-11-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Next weekend

[Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=553248635389801411&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

Recommended

Price (low to high)

Distance

Star rating

## Top Hotels Close to UCSF Mission Bay

![Exterior](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/f72650f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/76aa0c86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premier Room, Multiple Beds, High Floor (Corner Two King) | View from room](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/95dc6cbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Restaurant](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/26f4395c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### LUMA Hotel San Francisco

Mission Bay, 0.7 km from UCSF Mission Bay

9.6/10

Exceptional

(2372)

"Clean room and the staff were very friendly"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ben

CA $246

CA $290 total

includes taxes & fees

Dec 29 - Dec 30

[](https://www.expedia.ca/San-Francisco-Hotels-LUMA-Hotel-San-Francisco.h70097106.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/fc76649d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast (USD 16 per person)](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/f9d4387a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Sports facility](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/e11311b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/32000000/31420000/31419900/31419890/6a4e602e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Place San Francisco Downtown

1.1 km from UCSF Mission Bay

9.4/10

Exceptional

(1829)

"Great location and service. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Briseida

CA $151

CA $178 total

includes taxes & fees

Nov 30 - Dec 1

[](https://www.expedia.ca/San-Francisco-Hotels-Hyatt-Place-San-Francisco-Downtown.h31419890.Hotel-Information)

![Sundeck](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/ce95cac7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/2b503a50.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/4f46bfa5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/004f15cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel VIA

1.2 km from UCSF Mission Bay

9.2/10

Wonderful

(1485)

"Great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Tracy

CA $239

CA $281 total

includes taxes & fees

Dec 28 - Dec 29

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-VIA.h16819669.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/5800bbe5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/7856c00e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/1da5b062.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/d2b20643.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### InterContinental San Francisco by IHG

South of Market, 1.8 km from UCSF Mission Bay

9.2/10

Wonderful

(1013)

"Beautiful room and excellent food!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Melissa

CA $195

CA $288 total

includes taxes & fees

Dec 24 - Dec 25

[](https://www.expedia.ca/San-Francisco-Hotels-InterContinental-San-Francisco.h1766605.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/30000/22400/22303/ba451360.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite (Sutter)](https://images.trvl-media.com/lodging/1000000/30000/22400/22303/b362584a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/30000/22400/22303/0eeb6065.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/30000/22400/22303/50d108af.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Galleria Park Hotel

Financial District, 2.5 km from UCSF Mission Bay

9.6/10

Exceptional

(1011)

"Great value for the room, service and location "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Chao

CA $136

CA $218 total

includes taxes & fees

Nov 29 - Nov 30

[](https://www.expedia.ca/San-Francisco-Hotels-Galleria-Park-Hotel.h22303.Hotel-Information)

![3 bars/lounges](https://images.trvl-media.com/lodging/28000000/27120000/27110600/27110513/7ea03f76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![3 bars/lounges](https://images.trvl-media.com/lodging/28000000/27120000/27110600/27110513/921d3cab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/28000000/27120000/27110600/27110513/15b830b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/28000000/27120000/27110600/27110513/5931a034.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Canopy by Hilton San Francisco SoMa

1.7 km from UCSF Mission Bay

9.0/10

Wonderful

(1014)

"Room was very good and staff was excellent."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

velimir

CA $213

CA $250 total

includes taxes & fees

Dec 26 - Dec 27

[](https://www.expedia.ca/San-Francisco-Hotels-Canopy-By-Hilton-San-Francisco-SoMa.h27110513.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/500/491/5e565895.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch flat-screen TV with cable channels, TV, pay movies](https://images.trvl-media.com/lodging/1000000/10000/500/491/73838018.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/500/491/c9a2355d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Hypo-allergenic bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/1000000/10000/500/491/76fc74a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hyatt Regency San Francisco Downtown SOMA

South of Market, 2.2 km from UCSF Mission Bay

9.4/10

Exceptional

(1316)

"Great stay"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Eliran

CA $219

CA $314 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/San-Francisco-Hotels-The-Park-Central-San-Francisco-Hyatt-Affiliated-Hotel.h491.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/69c56718.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Coffee shop](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/c438fd26.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Reception](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/03417113.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Courtyard](https://images.trvl-media.com/lodging/1000000/700000/693700/693658/5023ecf8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Clancy, Autograph Collection by Marriott

1.9 km from UCSF Mission Bay

9.2/10

Wonderful

(1005)

"cleanliness,good service, convenient location"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Harry

CA $207

CA $302 total

includes taxes & fees

Dec 21 - Dec 22

[](https://www.expedia.ca/San-Francisco-Hotels-The-Clancy.h693658.Hotel-Information)

![Daily buffet breakfast (USD 22 per person)](https://images.trvl-media.com/lodging/70000000/69560000/69551600/69551553/w5519h4629x0y0-614e04d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/70000000/69560000/69551600/69551553/20cbbc17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, pillowtop beds, in-room safe, desk](https://images.trvl-media.com/lodging/70000000/69560000/69551600/69551553/f058590e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily buffet breakfast (USD 22 per person)](https://images.trvl-media.com/lodging/70000000/69560000/69551600/69551553/w4873h4411x3y0-976893ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### citizenM San Francisco Union Square

Union Square, 2.3 km from UCSF Mission Bay

9.4/10

Exceptional

(1424)

"Enjoyed our stay staff was friendly and helpful! Location was perfect!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ana

CA $150

CA $177 total

includes taxes & fees

Dec 25 - Dec 26

[](https://www.expedia.ca/San-Francisco-Hotels-CitizenM-San-Francisco-Union-Square.h69551553.Hotel-Information)

![Suite, 1 Bedroom, Corner](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321986/29f2f698.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Presidential Suite, 1 Bedroom](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321986/9c4e94de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premier Room, 1 King Bed](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321986/0fbc7ef6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Indoor pool](https://images.trvl-media.com/lodging/2000000/1330000/1322000/1321986/w4000h2662x0y0-fc84c036.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The St. Regis San Francisco

South of Market, 2.1 km from UCSF Mission Bay

9.4/10

Exceptional

(691)

"Had a great stay "

![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg)

Thomas

CA $506

CA $660 total

includes taxes & fees

Dec 12 - Dec 13

[](https://www.expedia.ca/San-Francisco-Hotels-The-St-Regis-San-Francisco.h1321986.Hotel-Information)

![Property entrance](https://images.trvl-media.com/lodging/2000000/1520000/1516000/1515923/72e31d9d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby sitting area](https://images.trvl-media.com/lodging/2000000/1520000/1516000/1515923/ed3ae5f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, 1 King Bed](https://images.trvl-media.com/lodging/2000000/1520000/1516000/1515923/cbebac64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/2000000/1520000/1516000/1515923/dd8901b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Orchard Garden Hotel

Chinatown, 2.7 km from UCSF Mission Bay

9.6/10

Exceptional

(1007)

"Great location, large room, fast check-in, friendly staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Wynette

CA $172

CA $206 total

includes taxes & fees

Dec 28 - Dec 29

[](https://www.expedia.ca/San-Francisco-Hotels-Orchard-Garden-Hotel.h1515923.Hotel-Information)

![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/6c2cdc12.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Deluxe Room, 1 Queen Bed, Accessible](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/w1781h1201x19y0-3696f576.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/3daecce1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, 1 King Bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/23500/23406/6a2ba7f8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Nikko San Francisco

Union Square, 2.4 km from UCSF Mission Bay

9.4/10

Exceptional

(2620)

"Clean room, convenient location, friendly people."

![Hong Kong SAR China](https://a.travel-assets.com/egds/marks/flags/hk.svg)

JING

CA $213

CA $316 total

includes taxes & fees

Dec 14 - Dec 15

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Nikko-San-Francisco.h23406.Hotel-Information)

![Outdoor spa tub](https://images.trvl-media.com/lodging/2000000/1150000/1145300/1145267/3ae7ddd9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby](https://images.trvl-media.com/lodging/2000000/1150000/1145300/1145267/8817fe11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Front of property](https://images.trvl-media.com/lodging/2000000/1150000/1145300/1145267/19a23635.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Rooftop terrace](https://images.trvl-media.com/lodging/2000000/1150000/1145300/1145267/17068cb1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Inn San Francisco

2.5 km from UCSF Mission Bay

9.6/10

Exceptional

(574)

"Amazing breakfast and staff is super helpful."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Stephanie

CA $326

CA $380 total

includes taxes & fees

Dec 1 - Dec 2

[](https://www.expedia.ca/San-Francisco-Hotels-Inn-San-Francisco.h1145267.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/1000000/800000/791800/791769/bff475ef.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/1000000/800000/791800/791769/fba34236.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/800000/791800/791769/ab6ff173.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Breakfast, lunch, dinner served; local and international cuisine ](https://images.trvl-media.com/lodging/1000000/800000/791800/791769/4df53291.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Four Seasons Hotel San Francisco

South of Market, 2.2 km from UCSF Mission Bay

9.4/10

Exceptional

(1006)

"great room and staff. "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

chunguang

CA $554

CA $652 total

includes taxes & fees

Dec 25 - Dec 26

[](https://www.expedia.ca/San-Francisco-Hotels-Four-Seasons-Hotel-San-Francisco.h791769.Hotel-Information)

![Lobby sitting area](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/944f985c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/57907250.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property entrance](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/17458474.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/20600/20547/588fe135.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Chancellor Hotel on Union Square

2.6 km from UCSF Mission Bay

9.2/10

Wonderful

(3061)

"Great location … friendly staff… would stay again "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Andrea

CA $117

CA $138 total

includes taxes & fees

Dec 1 - Dec 2

[](https://www.expedia.ca/San-Francisco-Hotels-Chancellor-Hotel-On-Union-Square.h20547.Hotel-Information)

![Exterior](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/7fe7eb3b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Flat-screen TV, pay movies, MP3 dock](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/4fdbdc64.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Flat-screen TV, pay movies, MP3 dock](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/398a6ca9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/290000/287200/287112/f11ecdc1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### W San Francisco

2 km from UCSF Mission Bay

9.0/10

Wonderful

(1009)

"Great Hotel! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Ricardo

CA $212

CA $299 total

includes taxes & fees

Dec 12 - Dec 13

[](https://www.expedia.ca/San-Francisco-Hotels-W-San-Francisco.h287112.Hotel-Information)

![Breakfast and dinner served](https://images.trvl-media.com/lodging/1000000/230000/225900/225819/b5cc10dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/230000/225900/225819/84c87d37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Junior Suite, 1 King Bed, City View, Corner | View from room](https://images.trvl-media.com/lodging/1000000/230000/225900/225819/d53576c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Premium bedding, in-room safe, desk, blackout drapes](https://images.trvl-media.com/lodging/1000000/230000/225900/225819/7f87fdc6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel Zelos San Francisco

South of Market, 2.2 km from UCSF Mission Bay

9.0/10

Wonderful

(1095)

"Nice room and restaurant! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Dustin

CA $187

CA $277 total

includes taxes & fees

Dec 14 - Dec 15

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-Zelos-San-Francisco.h225819.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/w4000h2663x0y0-df4f3756.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Property amenity](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/5653c9b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![View from property](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/189643db.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Banquet hall](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/952f2e20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Palace Hotel, a Luxury Collection Hotel, San Francisco

Financial District, 2.4 km from UCSF Mission Bay

9.2/10

Wonderful

(1007)

"Everything was fantastic including the breakfast!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

David

CA $380

CA $448 total

includes taxes & fees

Dec 23 - Dec 24

[](https://www.expedia.ca/San-Francisco-Hotels-Palace-Hotel.h27274.Hotel-Information)

![2 restaurants, breakfast, dinner served; Californian cuisine](https://images.trvl-media.com/lodging/1000000/10000/8800/8737/71913965.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/10000/8800/8737/6ae4adf1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cocktail bar](https://images.trvl-media.com/lodging/1000000/10000/8800/8737/b19064bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Cocktail bar](https://images.trvl-media.com/lodging/1000000/10000/8800/8737/w3996h2667x0y0-16c4604c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### San Francisco Marriott Marquis

South of Market, 2.1 km from UCSF Mission Bay

8.8/10

Excellent

(1239)

"Nice hotel "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Gabriel

CA $225

CA $315 total

includes taxes & fees

Dec 5 - Dec 6

[](https://www.expedia.ca/San-Francisco-Hotels-San-Francisco-Marriott-Marquis.h8737.Hotel-Information)

![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/24600/24540/918d5111.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Studio Suite, 1 King Bed](https://images.trvl-media.com/lodging/1000000/30000/24600/24540/a689a8ce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/1000000/30000/24600/24540/9ee74e51.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior entrance](https://images.trvl-media.com/lodging/1000000/30000/24600/24540/ebf8a29f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Hotel G San Francisco

2.5 km from UCSF Mission Bay

9.0/10

Wonderful

(1003)

"Clean room, nice staff"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Juan De

CA $142

CA $224 total

includes taxes & fees

Nov 29 - Nov 30

[](https://www.expedia.ca/San-Francisco-Hotels-Hotel-G-San-Francisco.h24540.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-12&endDate=2025-12-13&regionId=553248635389801411&adults=2&sort=RECOMMENDED&openPlayBack=true)

## Top UCSF Mission Bay Hotel Reviews

![Holiday Inn Golden Gateway by IHG](https://images.trvl-media.com/lodging/1000000/20000/10600/10538/9ba9bb1f_y.jpg)

### Holiday Inn Golden Gateway by IHG

10/10 Excellent

"Location"

[](https://expedia.ca/San-Francisco-Hotels-Holiday-Inn-Golden-Gateway.h10538.Hotel-Information)

![InterContinental San Francisco by IHG](https://images.trvl-media.com/lodging/2000000/1770000/1766700/1766605/5800bbe5_y.jpg)

### InterContinental San Francisco by IHG

10/10 Excellent

"👍"

[](https://expedia.ca/San-Francisco-Hotels-InterContinental-San-Francisco.h1766605.Hotel-Information)

![Palace Hotel, a Luxury Collection Hotel, San Francisco](https://images.trvl-media.com/lodging/1000000/30000/27300/27274/w4000h2663x0y0-df4f3756_y.jpg)

### Palace Hotel, a Luxury Collection Hotel, San Francisco

10/10 Excellent

"Hotel was beautiful and rooms were very clean and with a great view. "

[](https://expedia.ca/San-Francisco-Hotels-Palace-Hotel.h27274.Hotel-Information)

![Hilton San Francisco Financial District](https://images.trvl-media.com/lodging/1000000/10000/4400/4302/77af977e_y.jpg)

### Hilton San Francisco Financial District

10/10 Excellent

"My friend and I went there for Halloween weekend. It was a great trip. The hospitality of the hotel was amazing. Staff was great. Look forward to going back. Rooms were amazingly clean."

[](https://expedia.ca/San-Francisco-Hotels-Hilton-San-Francisco-Financial-District.h4302.Hotel-Information)

![Hotel VIA](https://images.trvl-media.com/lodging/17000000/16820000/16819700/16819669/ce95cac7_y.jpg)

### Hotel VIA

10/10 Excellent

"Great staff, room, view of the bay bridge and ballpark and elegant roof top bar and lounge!"

[](https://expedia.ca/San-Francisco-Hotels-Hotel-VIA.h16819669.Hotel-Information)

![Club Quarters Hotel in San Francisco](https://images.trvl-media.com/lodging/1000000/920000/913000/912982/5ee1ba27_y.jpg)

### Club Quarters Hotel in San Francisco

10/10 Excellent

"Very clean, comfy bed and down pillows with comforter, think white towel, good coffee in the lobby and water dispenser. Breakfast was delicious "

[](https://expedia.ca/San-Francisco-Hotels-Club-Quarters-Hotel-In-San-Francisco.h912982.Hotel-Information)

![citizenM San Francisco Union Square](https://images.trvl-media.com/lodging/70000000/69560000/69551600/69551553/755268ee_y.jpg)

### citizenM San Francisco Union Square

10/10 Excellent

"All good."

[](https://expedia.ca/San-Francisco-Hotels-CitizenM-San-Francisco-Union-Square.h69551553.Hotel-Information)

![Hyatt Regency San Francisco](https://images.trvl-media.com/lodging/1000000/30000/23800/23774/1f7903cc_y.jpg)

### Hyatt Regency San Francisco

10/10 Excellent

"Loved everything the room the food the view the hotel would stay again "

[](https://expedia.ca/San-Francisco-Hotels-Hyatt-Regency-San-Francisco.h23774.Hotel-Information)

![LUMA Hotel San Francisco ](https://images.trvl-media.com/lodging/71000000/70100000/70097200/70097106/f72650f9_y.jpg)

### LUMA Hotel San Francisco

10/10 Excellent

"Great location, clean rooms, courteous staff (including robos!). Went to concert at Chase: Luma was convenient AND a well appointed biz."

[](https://expedia.ca/San-Francisco-Hotels-LUMA-Hotel-San-Francisco.h70097106.Hotel-Information)

## Hotels near other UCSF Mission Bay attractions

[](https://www.expedia.ca/Chase-Center-Hotels.0-l553248635997928290-0.Travel-Guide-Filter-Hotels)

![Chase Center San Francisco Skyline Aerial Photography](https://images.trvl-media.com/place/553248635997928290/197c9322-47b4-4ac5-bc8c-d25b082862ed.jpg)

### Chase Center

Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its entertainment choices.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248635997928290)

[](https://www.expedia.ca/Anchor-Brewing-Company-Hotels.0-l6155048-0.Travel-Guide-Filter-Hotels)

![Anchor Brewing Company](https://images.trvl-media.com/place/6155048/89f44ad0-efe6-42e1-ae0f-9ec45d9f9269.jpg)

### Anchor Brewing Company

During your trip to San Francisco, you can search for that perfect souvenir at Anchor Brewing Company. Discover the top-notch restaurants and fascinating museums in this vibrant area.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6155048)

[](https://www.expedia.ca/Oracle-Park-Hotels.0-l6063199-0.Travel-Guide-Filter-Hotels)

![Always packed, lose or win. ](https://images.trvl-media.com/place/3132/6844d9ff-7d63-4da9-a600-a1e532dde0fd.jpg)

Photo by Zhou You

### Oracle Park

4.3/5 (2,839 reviews)

Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6063199)

[](https://www.expedia.ca/Mission-Bay-Conference-Center-At-UCSF-Hotels.0-l818566843354574848-0.Travel-Guide-Filter-Hotels)

### Mission Bay Conference Center at UCSF

Learn about the events happening at Mission Bay Conference Center at UCSF during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its entertainment choices.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=818566843354574848)

[](https://www.expedia.ca/Mission-Creek-Park-Hotels.0-l553248621555612179-0.Travel-Guide-Filter-Hotels)

### Mission Creek Park

Mission Creek Park is just one of the places to see in San Francisco, so why not enjoy the other things to explore during your travels? Experience the acclaimed art scene and fascinating museums in this vibrant area.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621555612179)

[](https://www.expedia.ca/Lefty-ODoul-Bridge-Hotels.0-l6155190-0.Travel-Guide-Filter-Hotels)

### Lefty O'Doul Bridge

You can find out about the history of San Francisco with a trip to Lefty O'Doul Bridge. Take in the fascinating museums and beautiful sunsets in this vibrant area.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=6155190)

[](https://www.expedia.ca/Letterform-Archive-Hotels.0-l866963133062057984-0.Travel-Guide-Filter-Hotels)

### Letterform Archive

You can find out about the history of San Francisco when you stop by Letterform Archive. Take in the live music and sunsets in this walkable area.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=866963133062057984)

[](https://www.expedia.ca/McLellan-Botanicals-Hotels.0-l553248621555612177-0.Travel-Guide-Filter-Hotels)

### McLellan Botanicals

Enjoy the beautiful sunsets and explore McLellan Botanicals, a lovely green space in San Francisco. Experience the fascinating museums and acclaimed theater scene in this vibrant area.

[See properties](https://www.expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests&regionId=553248621555612177)

## Frequently asked questions

### What's the area like around UCSF Mission Bay?

> UCSF Mission Bay is located in a vibrant area of San Francisco known for its top museums and stunning architecture. If you're looking for a convenient place to stay, check out the 79 hotels and other accommodations you'll find within a mile.

### Where is the best place to stay near UCSF Mission Bay?

> [LUMA Hotel San Francisco](https://www.expedia.ca/San-Francisco-Hotels-LUMA-Hotel-San-Francisco.h70097106.Hotel-Information) is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and a fitness center. It's located just a short 0.4 mi (0.7 km) from UCSF Mission Bay. Other good choices within a short distance include [Hyatt Place San Francisco Downtown](https://www.expedia.ca/San-Francisco-Hotels-Hyatt-Place-San-Francisco-Downtown.h31419890.Hotel-Information) and [Hotel VIA](https://www.expedia.ca/San-Francisco-Hotels-Hotel-VIA.h16819669.Hotel-Information).

### How many hotels are there close to UCSF Mission Bay?

> Expedia has 79 hotels and other accommodations within a mile from UCSF Mission Bay.

### If I need to cancel the hotel reservation for my stay near UCSF Mission Bay, will I receive a refund?

> Yes! You'll find that most room reservations are refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you have a non-refundable reservation, you might still have the option to cancel and receive a refund within 24 hours of your booking. Enter your dates, click on "Search", then you can filter by "fully refundable" to get the best options available near UCSF Mission Bay.

### What can I see and do near UCSF Mission Bay?

> Study the collections at San Francisco Museum of Modern Art, Asian Art Museum of San Francisco, or Market Street Railway Museum. Sights like San Francisco Mint, 450 Sutter Building, and Ferry Building are landmarks to visit in the area. You can check out the local talent at Golden Gate Theatre, Warfield Theatre, and Orpheum Theatre.

### How can I get to UCSF Mission Bay?

> With so many transportation options, seeing the area around UCSF Mission Bay is easy. Take advantage of metro transit at Market St & 5th St Stop, Market St & Taylor St Stop, and Powell St & Market St Stop. If you're taking a train into town, San Francisco Station is the closest station to Downtown San Francisco.

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-   [Omni Hotels in South Beach](https://www.expedia.ca/South-Beach-San-Francisco-Hotels-Omni.0-n6203131-0--bOmni.Travel-Guide-Filter-Hotels)
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-   [All Inclusive Resorts and in South of Market](https://www.expedia.ca/South-Of-Market-San-Francisco-Hotels-All-Inclusive-Hotel.0-n160166-0-tAllInclusiveHotel.Travel-Guide-Filter-Hotels)
-   [Boutique Hotels in South of Market](https://www.expedia.ca/South-Of-Market-San-Francisco-Hotels-Boutique-Hotel.0-n160166-0-tBoutiqueHotel.Travel-Guide-Filter-Hotels)
-   [Cheap Hotels in South of Market](https://www.expedia.ca/South-Of-Market-San-Francisco-Hotels-Cheap-Hotels.0-n160166-0-tCheapHotels.Travel-Guide-Filter-Hotels)
-   [Honeymoon Resorts and in South of Market](https://www.expedia.ca/South-Of-Market-San-Francisco-Hotels-Honeymoon-Hotels.0-n160166-0-tHoneymoonHotels.Travel-Guide-Filter-Hotels)
-   [Hotels with Free Parking in South of Market](https://www.expedia.ca/South-Of-Market-San-Francisco-Hotels-Hotels-With-Free-Parking.0-n160166-0-tHotelswithFreeParking.Travel-Guide-Filter-Hotels)
-   [Hotels with Hot Tubs in South of Market](https://www.expedia.ca/South-Of-Market-San-Francisco-Hotels-Hotels-With-Hot-Tubs.0-n160166-0-tHotelsWithHotTubs.Travel-Guide-Filter-Hotels)
-   [Lgbt Friendly Hotels in South of Market](https://www.expedia.ca/South-Of-Market-San-Francisco-Hotels-LGBT-Friendly-Hotel.0-n160166-0-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels)
-   [Luxury Hotels in South of Market](https://www.expedia.ca/South-Of-Market-San-Francisco-Hotels-Luxury-Hotel.0-n160166-0-tLuxuryHotel.Travel-Guide-Filter-Hotels)
-   [Oceanfront Hotels in South of Market](https://www.expedia.ca/South-Of-Market-San-Francisco-Hotels-Oceanfront-Hotels.0-n160166-0-tOceanfrontHotels.Travel-Guide-Filter-Hotels)
-   [Waterpark Hotels in South of Market](https://www.expedia.ca/South-Of-Market-San-Francisco-Hotels-Waterpark-Hotels.0-n160166-0-tWaterparkHotels.Travel-Guide-Filter-Hotels)
-   [Hotel Wedding Venues Hotels in South of Market](https://www.expedia.ca/South-Of-Market-San-Francisco-Hotels-Wedding-Hotels.0-n160166-0-tWeddingHotels.Travel-Guide-Filter-Hotels)
-   [South of Market Hotels](https://www.expedia.ca/South-Of-Market-San-Francisco-Hotels.0-n160166-0.Travel-Guide-Filter-Hotels)
-   [South Park Hotels](https://www.expedia.ca/South-Park-San-Francisco-Hotels.0-n553248621533114848-0.Travel-Guide-Filter-Hotels)
-   [Vacation Homes in UCSF Mission Bay Stop](https://www.expedia.ca/UCSF-Mission-Bay-Stop-Private-Vacation-Homes.d553248635996308167-aaPrivateVacationHomes.Travel-Guide-Accommodation)
-   [Guest Houses in UCSF/Chase Center Stop](https://www.expedia.ca/UCSFChase-Center-Stop-Guest-Houses.d553248635995265822-aaGuestHouses.Travel-Guide-Accommodation)
-   [Hotels near UCSF/Chase Center Stop](https://www.expedia.ca/UCSFChase-Center-Stop-Hotels.d553248635995265822.Travel-Guide-Hotels)
-   [Resorts in UCSF/Chase Center Stop](https://www.expedia.ca/UCSFChase-Center-Stop-Resort-Hotels.d553248635995265822-aaResortHotels.Travel-Guide-Accommodation)
-   [Union Square Hotels](https://www.expedia.ca/Union-Square-San-Francisco-Hotels.0-n800129-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Westfield Metreon](https://www.expedia.ca/Westfield-Metreon-Hotels.0-l6151549-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Yerba Buena Center for the Performing Arts](https://www.expedia.ca/Yerba-Buena-Center-For-The-Performing-Arts-Hotels.0-l6069415-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Yerba Buena Gardens](https://www.expedia.ca/Yerba-Buena-Gardens-Hotels.0-l6155654-0.Travel-Guide-Filter-Hotels)
-   [Hotels near Yerba Buena Ice Skating Center](https://www.expedia.ca/Yerba-Buena-Ice-Skating-Center-Hotels.0-l6155657-0.Travel-Guide-Filter-Hotels)

-   [Flights to San Francisco](https://www.expedia.ca/Cheap-Flights-To-San-Francisco.d178305.Travel-Guide-Flights)
-   [Flights from Vancouver (YVR) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yvr/sfo/vancouver-to-san-francisco)
-   [Flights from Toronto (YYZ) to San Francisco (SFO)](https://www.expedia.ca/lp/flights/yyz/sfo/toronto-to-san-francisco)

-   [Chase Center](https://www.expedia.ca/Chase-Center-Downtown-San-Francisco.d553248635997928290.Vacation-Attraction)
-   [Moscone Convention Center](https://www.expedia.ca/Moscone-Convention-Center-Downtown-San-Francisco.d502553.Vacation-Attraction)
-   [Oracle Park](https://www.expedia.ca/Oracle-Park-Downtown-San-Francisco.d6063199.Vacation-Attraction)
-   [Visit China Basin](https://www.expedia.ca/San-Francisco-China-Basin.dx553248635976476972)
-   [Visit Dogpatch](https://www.expedia.ca/San-Francisco-Dogpatch.dx553248635976007381)
-   [Visit Downtown San Francisco](https://www.expedia.ca/San-Francisco-Downtown-San-Francisco.dx6151902)
-   [Visit Rincon Hill](https://www.expedia.ca/San-Francisco-Rincon-Hill.dx553248635976481615)
-   [Visit South of Market](https://www.expedia.ca/San-Francisco-South-Of-Market.dx160166)
-   [Visit Union Square](https://www.expedia.ca/San-Francisco-Union-Square.dx800129)
-   [San Francisco Vacations](https://www.expedia.ca/San-Francisco.d178305.Destination-Travel-Guides)

-   [Car rentals near San Francisco](https://www.expedia.ca/Car-Rentals-In-San-Francisco.d178305.Car-Rental-Guide)
-   [Enterprise Rental Cars in South Beach](https://www.expedia.ca/Enterprise-Car-Rentals-In-South-Beach.d6203131-c15.Car-Rental-Guide-Suppliers)

-   [Things to do in San Francisco](https://www.expedia.ca/Things-To-Do-In-San-Francisco.d178305.Travel-Guide-Activities)