Title: Book the Best HISTORIC Hotels in Southeastern Indiana in 2025 | Expedia.ca [Southeastern Indiana Travel Guide](https://expedia.ca/Southeastern-Indiana.dx6233889)[Hotels in Southeastern Indiana](https://expedia.ca/Southeastern-Indiana-Hotels.d6233889.Travel-Guide-Hotels)[Vacation Rentals in Southeastern Indiana](https://expedia.ca/Southeastern-Indiana-Vacation-Rentals.d6233889.Travel-Guide-VacationRentals)[Flights to Southeastern Indiana](https://expedia.ca/Cheap-Flights-To-Southeastern-Indiana.d6233889.Travel-Guide-Flights)[Southeastern Indiana Car Rentals](https://expedia.ca/Car-Rentals-In-Southeastern-Indiana.d6233889.Car-Rental-Guide)[Southeastern Indiana Vacation Packages](https://expedia.ca/Southeastern-Indiana.d6233889.Destination-Travel-Guides) ![Frazier International History Museum showing heritage elements and interior views](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/297000/297374-Frazier-International-History-Museum.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Historic Hotels in Southeastern Indiana ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeastern Indiana Historic Hotels Tonight [Oct 29 - Oct 30](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2025-10-29&endDate=2025-10-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 30 - Oct 31](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2025-10-30&endDate=2025-10-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6233889&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Southeastern Indiana Historic Hotels ![Exterior](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/380612f2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, premium bedding, down comforters, in-room safe](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/70f22474.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/bf3651e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/13000000/12560000/12552800/12552757/84bc2f36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Louisville Downtown by IHG Downtown Louisville 8.8/10 Excellent (1581) "Very nice hotel, great breakfast, helpful staff, good location " ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Jeff CA $109 CA $128 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Louisville-Hotels-Holiday-Inn-Express-Suites-Louisville-Downtown.h12552757.Hotel-Information) ![Luxury Room](https://images.trvl-media.com/lodging/94000000/93090000/93082900/93082881/8a800e75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/94000000/93090000/93082900/93082881/d495ea0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/94000000/93090000/93082900/93082881/9be9137c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/94000000/93090000/93082900/93082881/233745dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Chandler Hotel Madison 10/10 Exceptional (115) "Lovely hotel, great stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie CA $212 CA $244 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Madison-Hotels-The-Chandler-Hotel.h93082881.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/840e31de.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/f0221042.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/4fd8456f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/1000000/10000/9900/9861/2a2a7fb6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Brown Hotel Downtown Louisville 9.4/10 Exceptional (1124) "Wonderful hotel with lots of history; clean rooms; Nice lounge and restaurants." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kim CA $212 CA $250 total includes taxes & fees Oct 30 - Oct 31 [](https://www.expedia.ca/Louisville-Hotels-The-Brown-Hotel.h9861.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/a9b7038a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/22b7d23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/cef338e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Louisville Downtown Louisville 9.2/10 Wonderful (1000) " Loved our stay, would definitely plan to come back if we are ever in the area again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Erica CA $225 CA $271 total includes taxes & fees Nov 20 - Nov 21 [](https://www.expedia.ca/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/3d017cc5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/aa5a75a0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/e898c223.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Full breakfast for a fee](https://images.trvl-media.com/lodging/1000000/30000/26000/25958/52012810.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Seelbach Hilton Louisville Downtown Downtown Louisville 8.6/10 Excellent (1001) "This was a lovely stay and we will definitely return. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dolorse CA $191 CA $225 total includes taxes & fees Nov 27 - Nov 28 [](https://www.expedia.ca/Louisville-Hotels-The-Seelbach-Hilton-Louisville.h25958.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/65000000/64700000/64696100/64696084/8f8322e9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, down comforters, desk, blackout drapes](https://images.trvl-media.com/lodging/65000000/64700000/64696100/64696084/5d16fd3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/65000000/64700000/64696100/64696084/22942c94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/65000000/64700000/64696100/64696084/w4000h2662x0y0-c69fbcac.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Towneplace Suites By Marriott Louisville Downtown Downtown Louisville 9.2/10 Wonderful (486) "Great location" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Lauren CA $135 CA $159 total includes taxes & fees Nov 16 - Nov 17 [](https://www.expedia.ca/Louisville-Hotels-Towneplace-Suites-By-Marriott-Louisville-Downtown.h64696084.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599840/5c04f012.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599840/2c34bd2f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Billiards](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599840/6093a6c0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/22000000/21600000/21599900/21599840/365889d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Louisville Downtown, KY Downtown Louisville 9.2/10 Wonderful (1000) "Very clean and comfortable property. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Amanda CA $159 CA $187 total includes taxes & fees Nov 21 - Nov 22 [](https://www.expedia.ca/Louisville-Hotels-Homewood-Suites-By-Hilton-Louisville-Downtown.h21599840.Hotel-Information) ![Dinner served](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/e02820b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/c4d1fb67.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/5bea9d61.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/10000000/9030000/9027600/9027531/f30004bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Embassy Suites Louisville Downtown Downtown Louisville 9.0/10 Wonderful (1049) "Nice room and great breakfast!! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shannon CA $170 CA $200 total includes taxes & fees Nov 9 - Nov 10 [](https://www.expedia.ca/Louisville-Hotels-Embassy-Suites-Louisville-Downtown.h9027531.Hotel-Information) ![Property grounds](https://images.trvl-media.com/lodging/39000000/38200000/38197900/38197897/f335a42d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![1 bedroom, iron/ironing board, bed sheets, wheelchair access](https://images.trvl-media.com/lodging/39000000/38200000/38197900/38197897/fe342391.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/39000000/38200000/38197900/38197897/e8eeb28d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/39000000/38200000/38197900/38197897/449f6063.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cozy Country Cabin quiet country retreat Orleans 10/10 Exceptional (183) "quiet. clean. beautiful property for this cabin setting" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Denise CA $157 CA $267 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/Orleans-Hotels-Cozy-Country-Cabin-Quiet-Country-Retreat.h38197897.Hotel-Information) ![Loft, 1 King Bed, Kitchen](https://images.trvl-media.com/lodging/120000000/119240000/119236900/119236820/2f059c41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 5 Bedrooms, Kitchen](https://images.trvl-media.com/lodging/120000000/119240000/119236900/119236820/c2ad0ada.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 5 Bedrooms, Kitchen](https://images.trvl-media.com/lodging/120000000/119240000/119236900/119236820/609b151b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/120000000/119240000/119236900/119236820/9b86d591.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### East Main Lofts Madison 7.4/10 Good (3) "Good location downtown. We liked that we could walk everywhere. Room was clean but had a musty smell. No towels were in the room when we checked in but the maids closet was open so we just grabbed some. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Thomas CA $190 CA $317 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Madison-Hotels-East-Main-Lofts.h119236820.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-12&endDate=2025-11-13®ionId=6233889&adults=2&specialized_stays_group_explore=historic_property&sort=RECOMMENDED&openPlayBack=true) ## Top Southeastern Indiana Hotel Reviews ![Holiday Inn Express New Albany - Louisville NW by IHG](//images.trvl-media.com/lodging/1000000/460000/456300/456275/a3ae5159_y.jpg) ### Holiday Inn Express New Albany - Louisville NW by IHG 10/10 Excellent "Wonderful, reasonably priced. Great beds and pillows. Great water pressure and shower head. Breakfast excellent. Some of the best biscuits and gravy ever! Had actual ketchup bottles and salt and pepper on the table. 10 stars" [](https://expedia.ca/Louisville-Hotels-Holiday-Inn-Express-New-Albany.h456275.Hotel-Information) ![Sheraton Louisville Riverside by Marriott](//images.trvl-media.com/lodging/1000000/20000/17900/17862/14fa367c_y.jpg) ### Sheraton Louisville Riverside by Marriott 10/10 Excellent "Good" [](https://expedia.ca/Louisville-Hotels-Sheraton-Louisville-Riverside-Hotel.h17862.Hotel-Information) ![Quality Suites Jeffersonville - Louisville North](//images.trvl-media.com/lodging/2000000/1520000/1513800/1513760/dbde1484_y.jpg) ### Quality Suites Jeffersonville - Louisville North 8/10 Good "The breakfast wasn't good. There were not many good options. No muffins or sweet breads were availiable and no fruit other than bruised apples. I made a waffle with the mix that was provided and the waffle tasted chemically. Room was very clean, bed was great, A/C was nice and cold. I expected the TV's to have Roku or better channel options. " [](https://expedia.ca/Louisville-Hotels-Quality-Suites.h1513760.Hotel-Information) ![Best Western Green Tree Inn](//images.trvl-media.com/lodging/1000000/30000/21100/21059/80ec0958_y.jpg) ### Best Western Green Tree Inn 10/10 Excellent "Very clean and quiet.." [](https://expedia.ca/Louisville-Hotels-Best-Western-Green-Tree-Inn.h21059.Hotel-Information) ![Radisson Hotel Louisville North](//images.trvl-media.com/lodging/1000000/30000/26400/26306/50b82654_y.jpg) ### Radisson Hotel Louisville North 10/10 Excellent "Counter service took to long. Asking for towels everyday sucks. " [](https://expedia.ca/Louisville-Hotels-Radisson-Hotel-Louisville-North.h26306.Hotel-Information) ![Hampton Inn New Albany Louisville West](//images.trvl-media.com/lodging/1000000/30000/25400/25301/eb53eba8_y.jpg) ### Hampton Inn New Albany Louisville West 10/10 Excellent "Very comfortable beds, good parking, pleasant staff, clean rooms, shower was good. My husband, his mother and i enjyes our stay" [](https://expedia.ca/Louisville-Hotels-Hampton-Inn-New-Albany-Louisville-West.h25301.Hotel-Information) ![Hampton Inn Louisville-North/Clarksville](//images.trvl-media.com/lodging/1000000/90000/85100/85064/2cfb06f6_y.jpg) ### Hampton Inn Louisville-North/Clarksville 10/10 Excellent "Everything was very clean. The very sweet lady who served breakfast was awesome!" 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[Southern Indiana Vacations](https://www.expedia.ca/Southern-Indiana.d6059635.Destination-Travel-Guides) - [Visit Southern Indiana](https://www.expedia.ca/Southern-Indiana.dx6059635) - [Visit Southwestern Indiana](https://www.expedia.ca/Southwestern-Indiana.dx6233876) - [Advantage Rent-A-Car Rental Cars in Ohio River Valley](https://www.expedia.ca/Advantage-Rent-A-Car-Car-Rentals-In-Ohio-River-Valley.d6233674-c3.Car-Rental-Guide-Suppliers) - [Pickup Car Rentals in Ohio River Valley](https://www.expedia.ca/Pickup-Car-Rentals-In-Ohio-River-Valley.d6233674-tPickup.Car-Rental-Guide-Class) - [Rent A Wreck Rental Cars in Southern Indiana](https://www.expedia.ca/Rent-A-Wreck-Car-Rentals-In-Southern-Indiana.d6059635-c33.Car-Rental-Guide-Suppliers) - [Thrifty Car Rental Rental Cars in Ohio River Valley](https://www.expedia.ca/Thrifty-Car-Rental-Car-Rentals-In-Ohio-River-Valley.d6233674-c45.Car-Rental-Guide-Suppliers) - [Things to do in Southern Indiana](https://www.expedia.ca/Things-To-Do-In-Southern-Indiana.d6059635.Travel-Guide-Activities) - 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