Title: Book the Best BUSINESS Hotels in Southeast Iowa in 2025 | Expedia.ca [Southeast Iowa Travel Guide](https://expedia.ca/Southeast-Iowa.dx6234151)[Hotels in Southeast Iowa](https://expedia.ca/Southeast-Iowa-Hotels.d6234151.Travel-Guide-Hotels)[Vacation Rentals in Southeast Iowa](https://expedia.ca/Southeast-Iowa-Vacation-Rentals.d6234151.Travel-Guide-VacationRentals)[Flights to Southeast Iowa](https://expedia.ca/Cheap-Flights-To-Southeast-Iowa.d6234151.Travel-Guide-Flights)[Southeast Iowa Car Rentals](https://expedia.ca/Car-Rentals-In-Southeast-Iowa.d6234151.Car-Rental-Guide)[Southeast Iowa Vacation Packages](https://expedia.ca/Southeast-Iowa.d6234151.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/55b2c6dee1b7995ed1033756cd63ca06.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Southeast Iowa - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southeast Iowa Business Hotels Tonight [Nov 4 - Nov 5](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2025-11-04&endDate=2025-11-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Nov 5 - Nov 6](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2025-11-05&endDate=2025-11-06&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2025-11-07&endDate=2025-11-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=6234151&startDate=2025-11-14&endDate=2025-11-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Southeast Iowa Business Hotels ![Terrace/patio](https://images.trvl-media.com/lodging/10000000/9540000/9534800/9534717/ef5745b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/10000000/9540000/9534800/9534717/1ce146a8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, down comforters, in-room safe, desk](https://images.trvl-media.com/lodging/10000000/9540000/9534800/9534717/7ab8182c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/10000000/9540000/9534800/9534717/7c968180.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Cobblestone Inn & Suites - Fort Madison Fort Madison 9.4/10 Exceptional (633) "One of the nicest hotels I've stayed at outside of a resort." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jeffery CA $105 CA $117 total includes taxes & fees Dec 1 - Dec 2 [](https://www.expedia.ca/Burlington-Hotels-Cobblestone-Inn-Suites-Fort-Madison.h9534717.Hotel-Information) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/130000/124500/124480/3c6f2deb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/124500/124480/22d5bdf7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/130000/124500/124480/21fbbb57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/130000/124500/124480/70da34b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### AmericInn by Wyndham Mount Pleasant Mount Pleasant 8.4/10 Very good (521) "We enjoyed the pool and this place is so clean and quiet." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Carol CA $106 CA $119 total includes taxes & fees Nov 10 - Nov 11 [](https://www.expedia.ca/Burlington-Hotels-AmericInn-By-Wyndham-Mount-Pleasant.h124480.Hotel-Information) ![Double Room, 2 Double Beds](https://images.trvl-media.com/lodging/1000000/60000/50100/50062/6f24ac33.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50100/50062/a8b48190.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Combined shower/tub, free toiletries, hair dryer, towels](https://images.trvl-media.com/lodging/1000000/60000/50100/50062/4d7961b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/1000000/60000/50100/50062/d2ec1e54.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Super 8 by Wyndham Mt Pleasant Mount Pleasant 8.2/10 Very good (830) "Room was had strong smoke aroma " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Katie CA $93 CA $104 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Burlington-Hotels-Super-8-By-Wyndham-Mt-Pleasant.h50062.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/50100/50061/8cc382f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/60000/50100/50061/83d7e11b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/60000/50100/50061/5af7a4bf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, Multiple Beds, Non Smoking (with Sofabed)](https://images.trvl-media.com/lodging/1000000/60000/50100/50061/ec3e4b14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Mt. Pleasant Inn Mount Pleasant 8.2/10 Very good (770) "Very quick stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Caren CA $101 CA $113 total includes taxes & fees Nov 5 - Nov 6 [](https://www.expedia.ca/Burlington-Hotels-Best-Western-Mt-Pleasant-Inn.h50061.Hotel-Information) ![Suite, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/1000000/50000/42600/42551/9d72170d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 7:00 AM to 11:00 PM, sun loungers](https://images.trvl-media.com/lodging/1000000/50000/42600/42551/5f87e5cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/1000000/50000/42600/42551/1ad9d408.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42600/42551/w5457h2908x0y5-b12d9c4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Keokuk North Keokuk 8.4/10 Very good (742) "Great staff! Clean hotel!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Matthew CA $118 CA $132 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Burlington-Hotels-Quality-Inn-Suites-Keokuk-North.h42551.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1480000/1478200/1478193/35b38c1b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1480000/1478200/1478193/13412084.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, open 6 AM to 11 PM, sun loungers](https://images.trvl-media.com/lodging/2000000/1480000/1478200/1478193/b1b8714b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 King Bed, Non Smoking | Living area](https://images.trvl-media.com/lodging/2000000/1480000/1478200/1478193/1463e145.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn Keokuk Keokuk 8.8/10 Excellent (633) "Good location for our time spent in Nauvoo. Breakfast was good, and the room was nice." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Michael CA $139 CA $155 total includes taxes & fees Dec 5 - Dec 6 [](https://www.expedia.ca/Burlington-Hotels-Hampton-Inn-Keokuk.h1478193.Hotel-Information) ![Indoor pool, open 7 AM to 10 PM, pool umbrellas](https://images.trvl-media.com/lodging/1000000/970000/966600/966544/28d171d7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/970000/966600/966544/7971d89d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/970000/966600/966544/88a74697.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/970000/966600/966544/42f91567.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Fort Madison near Hwy 61 Fort Madison 8.6/10 Excellent (565) "Staff was very friendly. Room was clean. Beds were comfortable. Breakfast was delicious." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Eric CA $114 CA $128 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Burlington-Hotels-Quality-Inn-Suites-Fort-Madison-Near-Hwy-61.h966544.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/1000000/30000/26200/26113/581c3c39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/26200/26113/85d2befc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/26200/26113/7532ee6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/30000/26200/26113/d7438490.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Burlington Burlington 8.4/10 Very good (294) "It was quiet & they gave us water, when we checked in, was hot out, so that was so nice!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Loren CA $155 CA $178 total includes taxes & fees Nov 7 - Nov 8 [](https://www.expedia.ca/Burlington-Hotels-Fairfield-Inn-Suites-By-Marriott-Burlington.h26113.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/30000/23100/23041/af493251.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/30000/23100/23041/2a99b8e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Bedroom](https://images.trvl-media.com/lodging/1000000/30000/23100/23041/10284cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/23100/23041/9e4a14f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Hotel & Suites Burlington by IHG Burlington 8.6/10 Excellent (458) "Hotel was very clean. Rooms were roomy and comfortable. Excellent free breakfast with good choices and plentiful seating." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Douglas CA $176 CA $202 total includes taxes & fees Nov 23 - Nov 24 [](https://www.expedia.ca/Burlington-Hotels-Holiday-Inn-Express-Hotel-Suites-Burlington.h23041.Hotel-Information) ![Water park](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/3ad09b6d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sports bar](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/786c2905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception hall](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/f77198ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/2000000/1810000/1803400/1803337/3d54b27e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fun City Resort Hotel Burlington 8.4/10 Very good (291) "This was kid friendly and there were options for the kids and adults to be entertained. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Dana [](https://www.expedia.ca/Burlington-Hotels-The-PZAZZ-Resort-Hotel.h1803337.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-18&endDate=2025-11-19®ionId=6234151&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Southeast Iowa Hotel Reviews ![Comfort Suites Burlington](//images.trvl-media.com/lodging/2000000/1190000/1183600/1183571/49287866_y.jpg) ### Comfort Suites Burlington 10/10 Excellent "Breakfast wasn’t very good. Since we stayed two nights on the weekend we were hoping for something other than reheated omelets the second day. " [](https://expedia.ca/Burlington-Hotels-Comfort-Suites-Burlington.h1183571.Hotel-Information) ![Cobblestone Inn & Suites - Fort Madison](//images.trvl-media.com/lodging/10000000/9540000/9534800/9534717/ef5745b9_y.jpg) ### Cobblestone Inn & Suites - Fort Madison 10/10 Excellent "One of the nicest hotels I've stayed at outside of a resort." [](https://expedia.ca/Burlington-Hotels-Cobblestone-Inn-Suites-Fort-Madison.h9534717.Hotel-Information) ![AmericInn by Wyndham West Burlington](//images.trvl-media.com/lodging/1000000/560000/550600/550579/55efdccb_y.jpg) ### AmericInn by Wyndham West Burlington 10/10 Excellent "Staff was very friendly. We enjoyed our stay." [](https://expedia.ca/Burlington-Hotels-AmericInn-By-Wyndham-West-Burlington.h550579.Hotel-Information) ![Holiday Inn Express Hotel & Suites Burlington by IHG](//images.trvl-media.com/lodging/1000000/30000/23100/23041/af493251_y.jpg) ### Holiday Inn Express Hotel & Suites Burlington by IHG 10/10 Excellent "Clean and friendly staff. Professional service." [](https://expedia.ca/Burlington-Hotels-Holiday-Inn-Express-Hotel-Suites-Burlington.h23041.Hotel-Information) ![Baymont by Wyndham Keokuk](//images.trvl-media.com/lodging/6000000/5090000/5087900/5087820/9b0e7059_y.jpg) ### Baymont by Wyndham Keokuk 10/10 Excellent "Air conditioning - Ok Cleanliness - bathroom and bedding were great. The floors were not so clean. Staff was helpful and friendly. Towels were replaced when requested. Location was good, but the street noise was noticeable. Pool was being refinished. " [](https://expedia.ca/Burlington-Hotels-Baymont-By-Wyndham-Keokuk.h5087820.Hotel-Information) ![Quality Inn & Suites Keokuk North](//images.trvl-media.com/lodging/1000000/50000/42600/42551/9d72170d_y.jpg) ### Quality Inn & Suites Keokuk North 10/10 Excellent "Very clean, staff were very nice. Easy to get to. Big room. Comfy couch and bed. Good value. Would stay here again. " [](https://expedia.ca/Burlington-Hotels-Quality-Inn-Suites-Keokuk-North.h42551.Hotel-Information) ![Quality Inn & Suites Fort Madison near Hwy 61](//images.trvl-media.com/lodging/1000000/970000/966600/966544/28d171d7_y.jpg) ### Quality Inn & Suites Fort Madison near Hwy 61 10/10 Excellent "Very clean place. Good services and super friendly. Definitely we are planning to come back to this hotel. " [](https://expedia.ca/Burlington-Hotels-Quality-Inn-Suites-Fort-Madison-Near-Hwy-61.h966544.Hotel-Information) ![Best Western Mt. Pleasant Inn](//images.trvl-media.com/lodging/1000000/60000/50100/50061/8cc382f9_y.jpg) ### Best Western Mt. Pleasant Inn 10/10 Excellent "Parking was great " [](https://expedia.ca/Burlington-Hotels-Best-Western-Mt-Pleasant-Inn.h50061.Hotel-Information) ![Hampton Inn Keokuk](//images.trvl-media.com/lodging/2000000/1480000/1478200/1478193/35b38c1b_y.jpg) ### Hampton Inn Keokuk 10/10 Excellent "Very good stay. I’ll definitely stay there again " [](https://expedia.ca/Burlington-Hotels-Hampton-Inn-Keokuk.h1478193.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Southeast Iowa cost? > Expect to pay between and per night for business-friendly hotels in Southeast Iowa. Awesome deals on stays that are suitable for corporate travelers are a click away on Expedia. These prices were available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply. ### How many business-friendly hotels are there in Southeast Iowa? > Southeast Iowa has business-friendly hotels to choose from. Whether you're attending a conference or working remotely, these properties are equipped with everything you need to be productive. ### Why book your business-friendly hotel in Southeast Iowa with Expedia? > Expedia will help you find a fabulous business-friendly hotel when work takes you on the road. From free WiFi and parking to gyms and spas, our stays come with all you'll need to settle that big contract. ### How can I find cheap business-friendly hotels in Southeast Iowa? > Expedia can help you easily find cheap business-friendly hotels in Southeast Iowa. Simply head to the "traveler experience" filter and click on "business friendly." This will show you properties with amenities designed to help you work comfortably and efficiently, like included breakfast and free WiFi. You can also choose your hotel star rating and budget to keep costs down. ### What is there to do in Southeast Iowa near my business-friendly hotel? > You'll find tons of attractions to see during your time in Southeast Iowa. 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