Title: Book the Best BUSINESS Hotels in Simpsonville in 2026 | Expedia.ca [Simpsonville Travel Guide](https://expedia.ca/Simpsonville.dx6239)[Hotels in Simpsonville](https://expedia.ca/Simpsonville-Hotels.d6239.Travel-Guide-Hotels)[Vacation Rentals in Simpsonville](https://expedia.ca/Simpsonville-Vacation-Rentals.d6239.Travel-Guide-VacationRentals)[Flights to Simpsonville](https://expedia.ca/Cheap-Flights-To-Simpsonville.d6239.Travel-Guide-Flights)[Simpsonville Car Rentals](https://expedia.ca/Car-Rentals-In-Simpsonville.d6239.Car-Rental-Guide)[Simpsonville Vacation Packages](https://expedia.ca/Simpsonville.d6239.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/bex-affinities/business.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/bex-affinities/business.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Simpsonville Business Hotels Tonight [Jan 29 - Jan 30](https://www.expedia.ca/Hotel-Search?regionId=6239&startDate=2026-01-29&endDate=2026-01-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Jan 30 - Jan 31](https://www.expedia.ca/Hotel-Search?regionId=6239&startDate=2026-01-30&endDate=2026-01-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Jan 30 - Feb 1](https://www.expedia.ca/Hotel-Search?regionId=6239&startDate=2026-01-30&endDate=2026-02-01&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Feb 6 - Feb 8](https://www.expedia.ca/Hotel-Search?regionId=6239&startDate=2026-02-06&endDate=2026-02-08&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Simpsonville business-friendly hotels ![Lobby lounge](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/5cc3b6ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![View from property](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/0d8d0617.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/95c63f23.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/120000/119100/119074/51a7c4d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Greenville Simpsonville [](https://www.expedia.ca/Simpsonville-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville-Simpsonville.h119074.Hotel-Information) Simpsonville 9.2/10 Wonderful (679 reviews) "Quick check in, and the rooms were clean!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) DENNIS CA $137 CA $151 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Simpsonville-Hotels-Fairfield-Inn-Suites-By-Marriott-Greenville-Simpsonville.h119074.Hotel-Information) ![Suite, Non Smoking](https://images.trvl-media.com/lodging/3000000/2990000/2986100/2986074/a3ff3e5d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2990000/2986100/2986074/ee72685c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2990000/2986100/2986074/b0c859da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/3000000/2990000/2986100/2986074/772de931.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Suites Simpsonville - Greenville [](https://www.expedia.ca/Simpsonville-Hotels-Comfort-Suites-Simpsonville.h2986074.Hotel-Information) Simpsonville 8.2/10 Very good (785 reviews) "Wonderful stay!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Barrie CA $122 CA $134 total includes taxes & fees Feb 21 - Feb 22 [](https://www.expedia.ca/Simpsonville-Hotels-Comfort-Suites-Simpsonville.h2986074.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/19000000/18990000/18989600/18989520/18e8e500.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/19000000/18990000/18989600/18989520/b9fd26fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/19000000/18990000/18989600/18989520/c06326d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/19000000/18990000/18989600/18989520/94e05ad9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Greenville SE - Simpsonville by IHG [](https://www.expedia.ca/Simpsonville-Hotels-Holiday-Inn-Express-Suites-Greenville-SE-Simpsonville.h18989520.Hotel-Information) Simpsonville 9.4/10 Exceptional (516 reviews) "Friendly staff and everything was well kept." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Ronny CA $173 CA $191 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/Simpsonville-Hotels-Holiday-Inn-Express-Suites-Greenville-SE-Simpsonville.h18989520.Hotel-Information) ![Desk, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/540000/533900/533881/0570b9fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/533900/533881/d8c4bcc7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/540000/533900/533881/e4cbaa99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/540000/533900/533881/dc2b86f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Simpsonville [](https://www.expedia.ca/Simpsonville-Hotels-Days-Inn-By-Wyndham-Simpsonville.h533881.Hotel-Information) Simpsonville 7.2/10 Good (424 reviews) "Breakfast was limited, rooms were ok, staff okay and nice. Bed had a smoke hole in the sheets. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rudes CA $95 CA $104 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Simpsonville-Hotels-Days-Inn-By-Wyndham-Simpsonville.h533881.Hotel-Information) ![Room, 2 Queen Beds, Non Smoking (Upgrade)](https://images.trvl-media.com/lodging/1000000/30000/24900/24842/8683611a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking (Upgrade)](https://images.trvl-media.com/lodging/1000000/30000/24900/24842/w2868h1920x0y0-e40e27dd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking (Upgrade)](https://images.trvl-media.com/lodging/1000000/30000/24900/24842/96d12f53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds, Non Smoking (Upgrade)](https://images.trvl-media.com/lodging/1000000/30000/24900/24842/9ddc6b2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Simpsonville - Greenville [](https://www.expedia.ca/Simpsonville-Hotels-Quality-Inn-Simpsonville-Greenville.h24842.Hotel-Information) Simpsonville 7.4/10 Good (167 reviews) "Clean, quiet very comfortable " ![United Kingdom](https://a.travel-assets.com/egds/marks/flags/uk.svg) Kathryn CA $84 CA $97 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Simpsonville-Hotels-Quality-Inn-Simpsonville-Greenville.h24842.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/5971f25f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Concierge desk](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/1d70fbe2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fireplace](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/92684d2c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Gazebo](https://images.trvl-media.com/lodging/23000000/22520000/22513500/22513453/1fc30205.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Greenville Woodruff Rd. [](https://www.expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information) Greenville 8.6/10 Excellent (110 reviews) "Great room, very clean and staff was friendly " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) James CA $101 CA $115 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Greenville-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Greenville-Woodruff-Rd.h22513453.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/f09ffe86.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/e91d409a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/b54ae3f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pillowtop beds, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/30000/23100/23003/fea97b11.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Greenville I-385 Inn & Suites [](https://www.expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) Greenville 9.0/10 Wonderful (1,429 reviews) "Excellent hotel nice and clean. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Irasema CA $105 CA $115 total includes taxes & fees Feb 1 - Feb 2 [](https://www.expedia.ca/Greenville-Hotels-Best-Western-Plus-Greenville-I-385-Inn-Suites.h23003.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/0007de95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor dining](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/074f4a70.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/f59bfe6c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/51000000/50830000/50828700/50828647/w1021h678x3y4-70d9704c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### DoubleTree by Hilton Greenville Woodruff Road [](https://www.expedia.ca/Greenville-Hotels-DoubleTree-By-Hilton-Greenville-Woodruff-Road.h50828647.Hotel-Information) Greenville 9.4/10 Exceptional (1,000 reviews) "Room for was super clean! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristina CA $158 CA $174 total includes taxes & fees Feb 22 - Feb 23 [](https://www.expedia.ca/Greenville-Hotels-DoubleTree-By-Hilton-Greenville-Woodruff-Road.h50828647.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/w3840h2556x0y3-09ad394d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/a3603352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/w3840h2556x0y3-b1b0c195.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/w3836h2877x4y3-4bdebee1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hyatt Place Greenville/Haywood [](https://www.expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) Greenville 7.8/10 Good (1,008 reviews) "Great staff, very helpful, fantastic beds and breakfast." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elizabeth CA $109 CA $120 total includes taxes & fees Feb 9 - Feb 10 [](https://www.expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![Lobby sitting area](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/dfd5de25.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/8ef1c109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/26c9fcbc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Non Smoking (Efficiency)](https://images.trvl-media.com/lodging/115000000/114590000/114583600/114583570/edaae4f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Woodspring Suites Greenville Airport [](https://www.expedia.ca/Greenville-Hotels-Woodspring-Suites-Greenville-Airport.h114583570.Hotel-Information) Greenville 8.4/10 Very good (332 reviews) "everything was perfect " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Makiya CA $107 CA $118 total includes taxes & fees Jan 30 - Jan 31 [](https://www.expedia.ca/Greenville-Hotels-Woodspring-Suites-Greenville-Airport.h114583570.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-02-12&endDate=2026-02-13®ionId=6239&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Simpsonville Hotel Reviews ![Sleep Inn Spartanburg Southwest](https://images.trvl-media.com/lodging/1000000/50000/42900/42867/5eb71761_y.jpg) ### Sleep Inn Spartanburg Southwest 10/10 Excellent "Room was very spotless and clean great staff and pet friendly hotel i would recommend anyone to come here 😀 me and my girlfriend had an amazing stay" [](https://expedia.ca/Spartanburg-Hotels-Sleep-Inn.h42867.Hotel-Information) ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/31b0d05e_y.jpg) ### Embassy Suites Greenville Golf Resort & Conference Center 10/10 Excellent "Room was spotless, staff was great, love the shower gel and shampoo! Always a good time at this facility - you never need to go out the hotel provides it all!" [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-Greenville-Golf-Resort-Conference-Center.h3223.Hotel-Information) ![Hampton Inn & Suites Greenville-Downtown-RiverPlace](https://images.trvl-media.com/lodging/2000000/1470000/1460400/1460359/d9184989_y.jpg) ### Hampton Inn & Suites Greenville-Downtown-RiverPlace 10/10 Excellent "Wonderful staff and perfect location " [](https://expedia.ca/Greenville-Hotels-Hampton-Inn-Suites-Greenville-Downtown-RiverPlace.h1460359.Hotel-Information) ![Embassy Suites by Hilton Greenville Downtown Riverplace](https://images.trvl-media.com/lodging/16000000/15060000/15052000/15051911/b5c8aa89_y.jpg) ### Embassy Suites by Hilton Greenville Downtown Riverplace 10/10 Excellent "The room was neat and clean. The cleaning and kitchen staff were very kind and courteous. It was a great stay." [](https://expedia.ca/Greenville-Hotels-Embassy-Suites-By-Hilton-Greenville-Downtown-Riverplace.h15051911.Hotel-Information) ![The Westin Poinsett Greenville](https://images.trvl-media.com/lodging/1000000/580000/576000/575983/3e47bf88_y.jpg) ### The Westin Poinsett Greenville 10/10 Excellent "Great hotel Great location Great room Friendly and courteous staff" [](https://expedia.ca/Greenville-Hotels-The-Westin-Poinsett-Greenville.h575983.Hotel-Information) ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](https://images.trvl-media.com/lodging/1000000/10000/1400/1379/91409d5a_y.jpg) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 10/10 Excellent "Everything was up to par " [](https://expedia.ca/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information) ![Hyatt Regency Greenville](https://images.trvl-media.com/lodging/1000000/30000/22300/22252/fa37e256_y.jpg) ### Hyatt Regency Greenville 10/10 Excellent ":Perfect " [](https://expedia.ca/Greenville-Hotels-Hyatt-Regency-Greenville.h22252.Hotel-Information) ![Hyatt Place Greenville/Haywood](https://images.trvl-media.com/lodging/1000000/70000/64600/64570/9a71f6a4_y.jpg) ### Hyatt Place Greenville/Haywood 10/10 Excellent "Friendly staff and comfortable room " [](https://expedia.ca/Greenville-Hotels-Hyatt-Place-GreenvilleHaywood.h64570.Hotel-Information) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/401b294d_y.jpg) ### Hilton Greenville 10/10 Excellent "Place is very" [](https://expedia.ca/Greenville-Hotels-Hilton-Greenville.h23172.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Simpsonville cost? ### What are the best business-friendly hotels in Simpsonville? ### How many business-friendly hotels are there in Simpsonville? ### What are the best cheap business-friendly hotels in Simpsonville? ### What are the top business-friendly motels in Simpsonville? ### Are there any family-friendly hotels in Simpsonville that are also business friendly? ### Why book your business-friendly hotel in Simpsonville with Expedia? ### How can I find cheap business-friendly hotels in Simpsonville? ### What is there to do in Simpsonville near my business-friendly hotel? ## Explore a world of travel with Expedia - 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