Santana Vacation Rentals

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Santana vacation rentals

Nature's Lodge Escape

Nature's Lodge Escape
Sabana Grande
8.6 out of 10, Excellent, (4 reviews)
"Beautiful "
United States
Vanessa C.
The price is CA $47
CA $122 total
includes taxes & fees
May 12 - May 13
Nature's Lodge Escape

Enjoy a cozy space in a RV Camper w/hot tub, near beaches.

Enjoy a cozy space in a RV Camper w/hot tub, near beaches.
Lajas
10.0 out of 10, Exceptional, (11 reviews)
"Very peaceful place near la parguera, Guanica beaches and Yauco art murals and coffee shops. "
United States
Eileen
The price is CA $135
CA $286 total
includes taxes & fees
May 3 - May 4
Enjoy a cozy space in a RV Camper w/hot tub, near beaches.

Glamping Mayaguez a delightful 20' container by My West Little Corner

Glamping Mayaguez a delightful 20' container by My West Little Corner
Mayagüez
9.8 out of 10, Exceptional, (8 reviews)
"Cynthia was a wonderful host and we enjoyed our time here very much."
United States
victoria h.
The price is CA $267
CA $321 total
includes taxes & fees
May 3 - May 4
Glamping Mayaguez a delightful 20' container by My West Little Corner

Camper Capacidad Hasta 6 Personas

Camper Capacidad Hasta 6 Personas
Cabo Rojo
The price is CA $97
CA $183 total
includes taxes & fees
May 4 - May 5
Camper Capacidad Hasta 6 Personas

Blue House Joyuda

Blue House Joyuda
3.5 star property
Cabo Rojo
9.4 out of 10, Exceptional, (38 reviews)
"Great experience, very pet friendly!"
United States
John
The price is CA $179
CA $191 total
includes taxes & fees
May 4 - May 5
Blue House Joyuda

Buye Apartments

Buye Apartments
3.0 star property
Cabo Rojo
8.4 out of 10, Very good, (46 reviews)
"This a perfect place to stay Is Clean comfortable, parking safe. the lady at the front desk was extremely nice "
United States
Mayra
The price is CA $154
CA $311 total
includes taxes & fees
May 3 - May 4
Buye Apartments

Palmeras Beach Apartments

Palmeras Beach Apartments
3.0 star property
Guanica
10.0 out of 10, Exceptional, (13 reviews)
"Excellent location and place to stay for a relax and low key getaway… just need your belongings. "
United States
Sayra
The price is CA $82
CA $221 total
includes taxes & fees
May 4 - May 5
Palmeras Beach Apartments

The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico

The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico
Adjuntas
9.6 out of 10, Exceptional, (15 reviews)
"A beautiful home and a great host! Strongly recommend! "
United States
Brandon C.
The price is CA $218
CA $388 total
includes taxes & fees
May 4 - May 5
The Cozy Càsata: A Unique American-Style Cabin in the Mountains of Puerto Rico

Bello Amanecer Guest House with Private Pool

Bello Amanecer Guest House with Private Pool
Añasco
9.8 out of 10, Exceptional, (27 reviews)
"Perfect for a get away with the the family! "
United States
Jose
The price is CA $231
CA $401 total
includes taxes & fees
May 6 - May 7
Bello Amanecer Guest House with Private Pool

Boqueron Beach and Country Cabins

Boqueron Beach and Country Cabins
2.5 star property
Boqueron
8.0 out of 10, Very good, (2 reviews)
"Cerca de Pobaldo y panadería "
Mexico
Julissa
The price is CA $205
CA $224 total
includes taxes & fees
May 4 - May 5
Boqueron Beach and Country Cabins

Serenity by Otium

Serenity by Otium
2.0 star property
Cabo Rojo
The price is CA $254
CA $724 total
includes taxes & fees
May 12 - May 13
Serenity by Otium

Cozy 2BR, Terrace, AC & WiFi near Tanama River

Cozy 2BR, Terrace, AC & WiFi near Tanama River
Utuado
10.0 out of 10, Exceptional, (1 review)
The price is CA $205
CA $430 total
includes taxes & fees
May 17 - May 18
Cozy 2BR, Terrace, AC & WiFi near Tanama River

2 bedroom Villa with Pool and Stunning Ocean Views.

2 bedroom Villa with Pool and Stunning Ocean Views.
La Mela
9.8 out of 10, Exceptional, (100 reviews)
"The property was amazing. Pool was clean and easily accessible. The kitchen is big and spacious. The rooms were Clean and comfortable. Will definitely come back to this villa!!!"
Canada
Rafael Antonio Torres
The price is CA $204
CA $410 total
includes taxes & fees
May 3 - May 4
2 bedroom Villa with Pool and Stunning Ocean Views.

Africa787 | A-Frame Wood House W/Pool @ Lajas

Africa787 | A-Frame Wood House W/Pool @ Lajas
Lajas
7.0 out of 10, Good, (2 reviews)
"The house was super cute but very dark and not a lot of lighting. There was 2 lizards and a dead roach in the house and the neighborhood/area was pretty sketch. The pool is more of a jacquzzi but still very nice, but the jets didn’t work. Otherwise, it was nice and cold and private. "
United States
Leanette G.
The price is CA $242
CA $423 total
includes taxes & fees
May 14 - May 15
Africa787 | A-Frame Wood House W/Pool @ Lajas

High Tide Guesthouse PR

High Tide Guesthouse PR
Lajas
9.6 out of 10, Exceptional, (27 reviews)
"The place is very clean, accessible air conditioner was amazing, highly recommend "
United States
Mayra
The price is CA $96
CA $166 total
includes taxes & fees
May 3 - May 4
High Tide Guesthouse PR

Ocean View Apt with Jacuzzi and Terrance in Playa Santa

Ocean View Apt with Jacuzzi and Terrance in Playa Santa
Guanica
10.0 out of 10, Exceptional, (6 reviews)
"Property was the cleanest place I’ve ever seen before. The quiet and peace I received from staying there. "
United States
Luis
The price is CA $140
CA $384 total
includes taxes & fees
May 4 - May 5
Ocean View Apt with Jacuzzi and Terrance in Playa Santa

Luxury Beach Villa | Pool | Buye Beach Retreat

Luxury Beach Villa | Pool | Buye Beach Retreat
Cabo Rojo
The price is CA $164
CA $409 total
includes taxes & fees
May 28 - May 29
Luxury Beach Villa | Pool | Buye Beach Retreat

OceanView Villa 2 - Amazing LOCATION, Bay Views & Pool mins from Boquerón town

OceanView Villa 2 - Amazing LOCATION, Bay Views & Pool mins from Boquerón town
Boquerón
9.4 out of 10, Exceptional, (47 reviews)
"Nice place "
United States
Jacob
The price is CA $168
CA $272 total
includes taxes & fees
May 13 - May 14
OceanView Villa 2 - Amazing LOCATION, Bay Views & Pool mins from Boquerón town

Beach House with Pool in Playa Santa - Casa Perla

Beach House with Pool in Playa Santa - Casa Perla
Guánica
9.8 out of 10, Exceptional, (6 reviews)
"Very clean and information of nearby stores and attractions made for a nice stay. Wonderful beach is 5 min walk. "
United States
Alicia A.
The price is CA $134
CA $306 total
includes taxes & fees
May 4 - May 5
Beach House with Pool in Playa Santa - Casa Perla

LOCATION! Beautiful Views! Tranquility! Restaurants & Nightlife 5 min drive!

LOCATION! Beautiful Views! Tranquility! Restaurants & Nightlife 5 min drive!
Boquerón
9.8 out of 10, Exceptional, (16 reviews)
"Is a wonderful location!"
United States
Willy R.
The price is CA $187
CA $312 total
includes taxes & fees
May 18 - May 19
LOCATION! Beautiful Views! Tranquility! Restaurants & Nightlife 5 min drive!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top Santana Hotel Reviews

Find out more about Santana

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.

As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Santana. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.

It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.

Frequently asked questions

Are there vacation rentals in Santana?

Yes, we give you a choice of vacation rentals near popular points of interest in Santana, or you can go with a more remote option if you want a relaxing place to stay.

What's the top vacation rental that Santana has to offer?

Blue House Joyuda: This vacation home rental near Santana is located near the beach and has an outdoor pool, a garden, and a barbecue grill to put you at ease in your new surroundings. Kitchen amenities include a fridge, a microwave, and a coffee maker.

What can I see and do in Santana?

While exploring the area, visit family-friendly sights like Surf 'N Fun Water Park, or get outside and enjoy nature at Bosque Estatal de Maricao. In the larger area, you’ll find Casa Morales and Church of Porta Coeli.

What are vacation rentals like in Santana?

Vacation rentals are privately owned accommodations you can stay in for a couple days or more in Santana. Vacation rentals feature amenities such as kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a sanitized environment, a vacation rental can offer a sense of privacy away from shared hotel elevators and busy concierge desks while still allowing you the experience of travel. You'll also get more space in a vacation rental than in a standard hotel, which makes a vacation rental a great choice for family trips or small group gatherings.