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    Check prices for these dates, December 13–14, 2026

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    Our top choices for Santa María hotels

    1. Hotel Sevilla Usulutan

    A pool area with lounge chairs and tables, surrounded by palm trees and a building with a tiled roof.

    2. Hotel Five Stars sv

    A modern bedroom with a large bed, a mirror, a wardrobe, and a nightstand with a lamp.

    3. Puerto Barillas Marina & Lodge

    A swimming pool with a thatched-roof structure and chairs in the background.

    4. Hotel Florencia San Miguel

    An outdoor dining area with wicker chairs and tables, a floral centerpiece, and a building with balconies in the background.

    5. Hacienda Rubí Club & Resort

    A modern building with a sloped roof, surrounded by lush greenery.

    6. Comfort Inn Real San Miguel

    A pool area with a brick patio, outdoor seating, and a building with a TV screen and a bar area.

    7. Hotel y Restaurante Mariana

    A pool area with a tiled floor, a covered walkway, and a view of a building with stairs and a flag.

    8. Hotel King del Centro San Miguel

    A person sitting on a couch in a room with a ceiling fan, a refrigerator, a red beverage dispenser, and a wooden coffee table.

    9. Hotel Los Mangos

    A luxurious resort with a large infinity pool reflecting the building and thatched-roof structures.

    10. Nido de Mar

    A beach with a boat on the water, a mountain in the background, and a clear sky.

    11. Palacio Real Hotel

    A bedroom with a bed, nightstand, and curtains.

    12. Punta Mango Surf & Beachfront Resort

    A room with two beds, a wooden floor, a view of the ocean, and a thatched roof.

    13. Paradise Bay

    A swimming pool with clear blue water, surrounded by lush greenery and palm trees.

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Top Santa María Hotel Reviews

    Puerto Barillas Marina & Lodge

    A swimming pool with a thatched-roof structure and chairs in the background.

    Hotel Five Stars sv

    A modern bedroom with a large bed, a mirror, a wardrobe, and a nightstand with a lamp.

    Hotel Florencia San Miguel

    An outdoor dining area with wicker chairs and tables, a floral centerpiece, and a building with balconies in the background.

    Hotel Los Mangos

    A luxurious resort with a large infinity pool reflecting the building and thatched-roof structures.

    Hotel y Restaurante Mariana

    A pool area with a tiled floor, a covered walkway, and a view of a building with stairs and a flag.

    Punta Mango Surf & Beachfront Resort

    A room with two beds, a wooden floor, a view of the ocean, and a thatched roof.

    Frequently Asked Questions

    What's the top vacation rental in Santa María?

    Charming 3-bedroom house with AC, WiFi in quaint Villas de San Andres, Quelepa: This vacation home rental outside of Santa María has air-conditioning and laundry facilities to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a fridge, a stovetop, and a microwave, so you can cook with friends or family. See all vacation rentals in Santa María.

    If I need to cancel my hotel reservation in Santa María, will I receive a refund?

    Yes, most hotel bookings are fully refundable as long as you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of your check-in date. If your reservation is non-refundable, it may still be possible to cancel it and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in Santa María.

    Where can I learn more about changing or cancelling my trip to Santa María?

    For more information about updating your trip to Santa María or cancelling it, click here.

    What is staying in Santa María like?

    Travelers to Santa María will find plenty to explore and enjoy. In Santa María, there are 2 hotels and other accommodations to choose from. Find out more about Santa María.

    What are the top places to visit in Santa María?

    Places to visit in the wider area include Alegria Lagoon, Bahia de Jiquilisco, and Isla Parjarito. You'll also find Church of Usulutan and Puerto Barillas Marina in the area. Check out what more to see and do in Expedia's Santa María guide.

    Where is the best place to stay in Santa María?

    Based on our traveler data, Hotel Sevilla Usulutan is one of the top choices for your stay. This hotel offers a restaurant and an outdoor pool. Two other choices for your stay in the area are Hotel Los Mangos and Hotel Florencia San Miguel. See all available top hotels, or vacation rentals in Santa María.