Title: Book the Best BUSINESS Hotels in Santa Maria in 2026 | Expedia.ca [Santa Maria Travel Guide](https://expedia.ca/Santa-Maria.dx3224)[Hotels in Santa Maria](https://expedia.ca/Santa-Maria-Hotels.d3224.Travel-Guide-Hotels)[Vacation Rentals in Santa Maria](https://expedia.ca/Santa-Maria-Vacation-Rentals.d3224.Travel-Guide-VacationRentals)[Flights to Santa Maria](https://expedia.ca/Cheap-Flights-To-Santa-Maria.d3224.Travel-Guide-Flights)[Things to do in Santa Maria](https://expedia.ca/Things-To-Do-In-Santa-Maria.d3224.Travel-Guide-Activities)[Santa Maria Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Maria.d3224.Car-Rental-Guide)[Santa Maria Vacation Packages](https://expedia.ca/Santa-Maria.d3224.Destination-Travel-Guides) ![Vineyard in Santa Maria California; Shutterstock ID 206444242](https://images.trvl-media.com/place/3224/ba8b33be-89d4-4e66-b78a-b7d7bf6cc964.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Santa Maria, CA from CA $115 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Santa Maria Business Hotels Tonight [Dec 8 - Dec 9](https://www.expedia.ca/Hotel-Search?regionId=3224&startDate=2025-12-08&endDate=2025-12-09&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 9 - Dec 10](https://www.expedia.ca/Hotel-Search?regionId=3224&startDate=2025-12-09&endDate=2025-12-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=3224&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=3224&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Top Santa Maria Business Hotels ![Reception](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/1cf0eed4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, cribs/infant beds](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/d9c1ee80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/70982f53.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/39000000/38230000/38230000/38229980/0f7b2fce.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Santa Maria Santa Maria 9.4/10 Exceptional (1006) "Lovely hotel" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Adrian CA $148 CA $167 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Hampton-Inn-Suites-Santa-Maria.h38229980.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/w3840h2557x0y3-fef746b6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hypo-allergenic bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/w3836h2557x4y3-8640246b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/e01e83cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/20000/12500/12424/w3837h2557x3y3-e09a7f68.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Homewood Suites by Hilton Santa Maria Santa Maria 8.4/10 Very good (34) "Friendly staff and nice hotel." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elisa CA $165 CA $186 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Santa-Maria-Hotels-Homewood-Suites-By-Hilton-Santa-Maria.h12424.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/71e9333e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Meeting facility](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/f81f9296.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, blackout drapes, iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/acdb3ea9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/440000/433700/433636/33b4a0e3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Radisson Hotel Santa Maria Santa Maria 7.6/10 Good (1325) "Very nice hotel. It is currently being renovated." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Elsa CA $136 CA $153 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Radisson-Hotel-Santa-Maria.h433636.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/53eb999c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/373b886f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Master Suite](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/b334fb79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/0396337b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic Santa Maria Inn Santa Maria 8.4/10 Very good (1841) "Our room was awesome, the check in was quick and easy, the bar was open later and we had a great time" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Melody CA $111 CA $125 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) ![Restaurant](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/fda3cb7d_edited_c5f0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/w5755h3835x5y5-f126bb4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property entrance](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/dc279f99.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, blackout drapes](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/1170bb3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Plus Big America Santa Maria 8.8/10 Excellent (1005) "great place - clean n comfy beds " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy CA $151 CA $169 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Best-Western-Plus-Big-America.h15345.Hotel-Information) ![Front of property - evening/night](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/ecb45d63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby lounge](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/1bbd8589.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/c2079151.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/40000000/39520000/39514500/39514495/2344a3d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Wine Stone Inn Santa Maria 9.8/10 Exceptional (600) "Room was super clean and roomy ...bed was very comfortable! Love the decor in the entire hotel. Staff was friendly and accommodating. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) shannon CA $218 CA $259 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Wine-Stone-Inn.h39514495.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733222/6f4a6585.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733222/6d7d8e79.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733222/be90ec77.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 2 Queen Beds](https://images.trvl-media.com/lodging/3000000/2740000/2733300/2733222/0b303e7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn & Suites by Marriott Santa Maria Santa Maria 8.6/10 Excellent (721) "Staff for breakfast" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kiari CA $155 CA $174 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Fairfield-Inn-Suites-By-Marriott-Santa-Maria.h2733222.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088174/cc3976ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088174/0e007283.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free cribs/infant beds, free WiFi](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088174/357603c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Double Beds](https://images.trvl-media.com/lodging/2000000/1090000/1088200/1088174/483bd489.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn by Wyndham Santa Maria Santa Maria 6.8/10 (1003) "Room was clean staff was nice. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kimberly Dawn CA $102 CA $115 total includes taxes & fees Dec 11 - Dec 12 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Days-Inn-By-Wyndham-Santa-Maria.h1088174.Hotel-Information) ![Studio Suite, 2 Double Beds](https://images.trvl-media.com/lodging/3000000/2620000/2618300/2618252/0df55700.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/3000000/2620000/2618300/2618252/11245da2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed, Accessible (Comm, Mobil, Accessible Tub)](https://images.trvl-media.com/lodging/3000000/2620000/2618300/2618252/7a94e28d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/3000000/2620000/2618300/2618252/5fae8499.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Candlewood Suites Santa Maria by IHG Santa Maria 8.6/10 Excellent (1001) "Nice, clean hotel " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) janice CA $137 CA $154 total includes taxes & fees Dec 14 - Dec 15 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Candlewood-Suites-Santa-Maria.h2618252.Hotel-Information) ![Outdoor pool, open 8:00 AM to 10:00 PM, pool umbrellas, sun loungers](https://images.trvl-media.com/lodging/115000000/114590000/114580800/114580787/705a0cba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Courtyard](https://images.trvl-media.com/lodging/115000000/114590000/114580800/114580787/af149da4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, in-room safe, individually decorated, desk](https://images.trvl-media.com/lodging/115000000/114590000/114580800/114580787/a265b0b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/115000000/114590000/114580800/114580787/7deb9c0a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Village Inn Lompoc 9.6/10 Exceptional (82) "Everything was clean very nice grounds Pool and Jacuzzi Restaurant and Bar was Great and very convenient right off freeway!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) David CA $177 CA $202 total includes taxes & fees Dec 10 - Dec 11 [](https://www.expedia.ca/Lompoc-Hotels-Village-Inn.h114580787.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-23&endDate=2025-12-24®ionId=3224&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Santa Maria Hotel Reviews ![Sideways Inn](https://images.trvl-media.com/lodging/1000000/20000/14100/14031/f6afc1e5_y.jpg) ### Sideways Inn 10/10 Excellent "Nice stay" [](https://expedia.ca/Santa-Barbara-Hotels-Sideways-Inn.h14031.Hotel-Information) ![Pea Soup Andersen's Inn](https://images.trvl-media.com/lodging/1000000/20000/19400/19331/1b7acd45_y.jpg) ### Pea Soup Andersen's Inn 10/10 Excellent "Very good " [](https://expedia.ca/Santa-Barbara-Hotels-Pea-Soup-Andersens-Inn.h19331.Hotel-Information) ![Vinland Hotel and Lounge](https://images.trvl-media.com/lodging/1000000/20000/19500/19473/cd77ad55_y.jpg) ### Vinland Hotel and Lounge 10/10 Excellent "Is relaxing. " [](https://expedia.ca/Santa-Barbara-Hotels-Vinland-Hotel-And-Lounge.h19473.Hotel-Information) ![Best Western Plus Big America](https://images.trvl-media.com/lodging/1000000/20000/15400/15345/fda3cb7d_edited_c5f0_y.jpg) ### Best Western Plus Big America 10/10 Excellent "Yea" [](https://expedia.ca/San-Luis-Obispo-Hotels-Best-Western-Plus-Big-America.h15345.Hotel-Information) ![Historic Santa Maria Inn](https://images.trvl-media.com/lodging/1000000/30000/20400/20393/53eb999c_y.jpg) ### Historic Santa Maria Inn 10/10 Excellent "Professional " [](https://expedia.ca/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) ![Cottage Inn By The Sea](https://images.trvl-media.com/lodging/1000000/160000/151000/150921/c54d7346_y.jpg) ### Cottage Inn By The Sea 10/10 Excellent "We always stay at the Cottage Inn. The staff is awesome and the property is amazing." [](https://expedia.ca/San-Luis-Obispo-Hotels-Cottage-Inn-By-The-Sea.h150921.Hotel-Information) ![Oxford Suites Pismo Beach](https://images.trvl-media.com/lodging/1000000/10000/3100/3089/b427747a_y.jpg) ### Oxford Suites Pismo Beach 10/10 Excellent "Clean room " [](https://expedia.ca/San-Luis-Obispo-Hotels-Oxford-Suites-Pismo-Beach.h3089.Hotel-Information) ![Wine Valley Inn](https://images.trvl-media.com/lodging/1000000/50000/41300/41236/92aad964_y.jpg) ### Wine Valley Inn 10/10 Excellent "Nice room w/fireplace - Excellent breakfast! Very nice and helpful staff! Thank U!" [](https://expedia.ca/Santa-Barbara-Hotels-Wine-Valley-Inn.h41236.Hotel-Information) ![SeaCrest OceanFront Hotel](https://images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/w3000h1999x0y0-15b2e131_y.jpg) ### SeaCrest OceanFront Hotel 10/10 Excellent "Our room had a large balcony and from it during daylight hours we could see the ocean. The hotel is on a bluff but has stairs where guests can walk down to Pismo Beach and walk for miles on the pristine sand and then on the Boardwalk. You can also walk to the cute shops and onto the Pismo Pier. The pier has a Christmas tree lit up at night that you can see from the hotel." [](https://expedia.ca/San-Luis-Obispo-Hotels-SeaCrest-OceanFront-Hotel.h1365352.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Santa Maria cost? ### What are the best business-friendly hotels in Santa Maria? ### How many business-friendly hotels are there in Santa Maria? ### What are the best cheap business-friendly hotels in Santa Maria? ### What are the top business-friendly motels in Santa Maria? ### Are there any family-friendly hotels in Santa Maria that are also business friendly? ### Why book your business-friendly hotel in Santa Maria with Expedia? ### How can I find cheap business-friendly hotels in Santa Maria? ### What is there to do in Santa Maria near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Adults Only Resorts & in Central Coast California ](https://www.expedia.ca/Central-Coast-California-Hotels-Adults-Only-Resorts.0-0-d6055477-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels) - 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