Title: Hotels by Best Western in Santa Maria from CA $144 | Expedia.ca [Santa Maria Travel Guide](https://expedia.ca/Santa-Maria.dx3224)[Hotels in Santa Maria](https://expedia.ca/Santa-Maria-Hotels.d3224.Travel-Guide-Hotels)[Vacation Rentals in Santa Maria](https://expedia.ca/Santa-Maria-Vacation-Rentals.d3224.Travel-Guide-VacationRentals)[Flights to Santa Maria](https://expedia.ca/Cheap-Flights-To-Santa-Maria.d3224.Travel-Guide-Flights)[Things to do in Santa Maria](https://expedia.ca/Things-To-Do-In-Santa-Maria.d3224.Travel-Guide-Activities)[Santa Maria Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Maria.d3224.Car-Rental-Guide)[Santa Maria Vacation Packages](https://expedia.ca/Santa-Maria.d3224.Destination-Travel-Guides) ![](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/51000/51689-Santa-Barbara-Wine-Country.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Best Western in Santa Maria from CA $144 ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Oct 24 - Oct 25](https://www.expedia.ca/Hotel-Search?regionId=3224&startDate=2025-10-24&endDate=2025-10-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Oct 25 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=3224&startDate=2025-10-25&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Oct 24 - Oct 26](https://www.expedia.ca/Hotel-Search?regionId=3224&startDate=2025-10-24&endDate=2025-10-26&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Oct 31 - Nov 2](https://www.expedia.ca/Hotel-Search?regionId=3224&startDate=2025-10-31&endDate=2025-11-02&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Santa Maria Best Western Hotels ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/e16ece78.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/4cda8af4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/8d75e25e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Room, 2 Queen Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/30000/23100/23008/a9f9803a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Best Western Casa Grande Inn Pismo Beach 8.8/10 Excellent (1128) "Enjoyed our stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Laura CA $127 CA $144 total includes taxes & fees Nov 2 - Nov 3 [](https://www.expedia.ca/San-Luis-Obispo-Hotels-Best-Western-Casa-Grande-Inn.h23008.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-07&endDate=2025-11-08®ionId=3224&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Hotels-Best-Western.0-0-d3224--bBestWestern.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Maria-Hotels-Best-Western.0-0-d3224--bBestWestern.Travel-Guide-Filter-Hotels) ## Top Santa Maria Hotel Reviews ![Hotel Avanti](//images.trvl-media.com/lodging/103000000/102800000/102791800/102791710/c06a634d_y.jpg) ### Hotel Avanti 10/10 Excellent "Clean room. As a wheelchair user, I got their ADA room. It was wonderful! It’s honestly probably the best ADA hotel I’ve stayed at as far as accessibility in the room." [](https://expedia.ca/Santa-Maria-Hotels-Hotel-Avanti.h102791710.Hotel-Information) ![Historic Santa Maria Inn](//images.trvl-media.com/lodging/1000000/30000/20400/20393/53eb999c_y.jpg) ### Historic Santa Maria Inn 10/10 Excellent "Very nostalgic atmosphere, and bed is so comfortable." [](https://expedia.ca/Santa-Maria-Hotels-Historic-Santa-Maria-Inn.h20393.Hotel-Information) ![Radisson Hotel Santa Maria](//images.trvl-media.com/lodging/1000000/440000/433700/433636/71e9333e_y.jpg) ### Radisson Hotel Santa Maria 10/10 Excellent "Great Hotel location! Literally next to the Airport and near shopping and eating type places! Great outdoor views of runway, if you are into plane watching like me! Oh, and the beds are comfortable! Honestly, that was the best for me. I didn't want to get out. Sweeeeet!" [](https://expedia.ca/San-Luis-Obispo-Hotels-Radisson-Hotel-Santa-Maria.h433636.Hotel-Information) ![Wine Valley Inn](//images.trvl-media.com/lodging/1000000/50000/41300/41236/92aad964_y.jpg) ### Wine Valley Inn 10/10 Excellent "Beautiful facility; great location within town." [](https://expedia.ca/Santa-Barbara-Hotels-Wine-Valley-Inn.h41236.Hotel-Information) ![King Frederik Inn](//images.trvl-media.com/lodging/1000000/10000/6100/6033/a036e931_y.jpg) ### King Frederik Inn 10/10 Excellent "We just NEEDED a respite from stress and the King Frederik gave that to us! Quiet, clean, comfort, lovely amenities,great quick breakfast with delish pastries! We had a wonderful stay! Thank you! " [](https://expedia.ca/Santa-Barbara-Hotels-King-Frederik-Inn.h6033.Hotel-Information) ![Motel 6 Santa Maria, CA - North](//images.trvl-media.com/lodging/1000000/1000000/996400/996393/5265532a_y.jpg) ### Motel 6 Santa Maria, CA - North 10/10 Excellent "Didn't Get The Guys Name. But He Had Glasses. Very Nice Guy. Check In Was So Easy. " [](https://expedia.ca/San-Luis-Obispo-Hotels-Motel-6-Santa-Maria.h996393.Hotel-Information) ![Sandcastle Hotel on the Beach](//images.trvl-media.com/lodging/1000000/50000/41000/40915/89d1e3f1_y.jpg) ### Sandcastle Hotel on the Beach 10/10 Excellent "All staff was very helpful and friendly. We didn't like having to pay for parking all three days we stayed there." [](https://expedia.ca/San-Luis-Obispo-Hotels-Sandcastle-Hotel-On-The-Beach.h40915.Hotel-Information) ![Shore Cliff Hotel](//images.trvl-media.com/lodging/1000000/10000/9800/9742/ff9d613b_y.jpg) ### Shore Cliff Hotel 10/10 Excellent "Better breakfast options" [](https://expedia.ca/San-Luis-Obispo-Hotels-Shore-Cliff-Hotel.h9742.Hotel-Information) ![SeaCrest OceanFront Hotel](//images.trvl-media.com/lodging/2000000/1370000/1365400/1365352/w3000h1999x0y0-15b2e131_y.jpg) ### SeaCrest OceanFront Hotel 10/10 Excellent "Great property " [](https://expedia.ca/San-Luis-Obispo-Hotels-SeaCrest-OceanFront-Hotel.h1365352.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - More ways to book - [Hilton Hotels in Avila Beach](https://www.expedia.ca/Avila-Beach-Hotels-Hilton-Hotels.0-0-d11911--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Wyndham Hotels in Buellton](https://www.expedia.ca/Buellton-Hotels-Wyndham-Hotels.0-0-d6967--bWyndhamHotels.Travel-Guide-Filter-Hotels) - 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[Flights from Carson City (CSN) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/csn/smx/carson-city-to-santa-maria) - [Flights from Cancun (CUN) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/cun/smx/cancun-to-santa-maria) - [Flights from Detroit (DTW) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/dtw/smx/detroit-to-santa-maria) - [Flights from Dubai (DXB) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/dxb/smx/dubai-to-santa-maria) - [Flights from Elko (EKO) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/eko/smx/elko-to-santa-maria) - [Flights from Fort Lauderdale (FLL) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/fll/smx/fort-lauderdale-to-santa-maria) - [Flights from Honolulu (HNL) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/hnl/smx/honolulu-to-santa-maria) - [Flights from Istanbul (IST) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/ist/smx/istanbul-to-santa-maria) - [Flights from Jackson (JAN) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/jan/smx/jackson-to-santa-maria) - 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[Flights from Montreal (YUL) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/yul/smx/montreal-to-santa-maria) - [Flights from Vancouver (YVR) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/yvr/smx/vancouver-to-santa-maria) - [Flights from Winnipeg (YWG) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/ywg/smx/winnipeg-to-santa-maria) - [Flights from Saskatoon (YXE) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/yxe/smx/saskatoon-to-santa-maria) - [Flights from Calgary (YYC) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/yyc/smx/calgary-to-santa-maria) - [Flights from Victoria (YYJ) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/yyj/smx/victoria-to-santa-maria) - [Flights from Toronto (YYZ) to Santa Maria (SMX)](https://www.expedia.ca/lp/flights/yyz/smx/toronto-to-santa-maria) - [Santa Maria Valley Historical Society](https://www.expedia.ca/Santa-Maria-Valley-Historical-Society-Santa-Maria.d553248621561135488.Vacation-Attraction) - [Rental cars Santa Maria Public airport](https://www.expedia.ca/Car-Rentals-In-Santa-Maria-Public.d6031989.Car-Rental-Guide) - 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