Title: Book The Best Hotels in Santa Isabel Cholula for 2026 from CA $62 - Fully Refundable Options - Expedia.ca [Vacation Rentals in Santa Isabel Cholula](https://expedia.ca/Santa-Isabel-Cholula-Vacation-Rentals.d553248635640697179.Travel-Guide-VacationRentals)[Santa Isabel Cholula Car Rentals](https://expedia.ca/Car-Rentals-In-Santa-Isabel-Cholula.d553248635640697179.Car-Rental-Guide)[Santa Isabel Cholula Vacation Packages](https://expedia.ca/Santa-Isabel-Cholula.d553248635640697179.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find hotels in Santa Isabel Cholula from CA $62 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in Santa Isabel Cholula Family friendly [](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel+Cholula%2C+Puebla%2C+Mexico®ionId=553248635640697179&latLong=18.974833%2C-98.385318&adults=2&startDate=2026-01-09&d1=2026-01-09&endDate=2026-01-11&d2=2026-01-11&travelerType=family_friendly) Spa [](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel+Cholula%2C+Puebla%2C+Mexico®ionId=553248635640697179&latLong=18.974833%2C-98.385318&adults=2&startDate=2026-01-09&d1=2026-01-09&endDate=2026-01-11&d2=2026-01-11&amenities=SPA_ON_SITE) Apart hotel [](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel+Cholula%2C+Puebla%2C+Mexico®ionId=553248635640697179&latLong=18.974833%2C-98.385318&adults=2&startDate=2026-01-09&d1=2026-01-09&endDate=2026-01-11&d2=2026-01-11&lodging=APART_HOTEL) Pool [](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel+Cholula%2C+Puebla%2C+Mexico®ionId=553248635640697179&latLong=18.974833%2C-98.385318&adults=2&startDate=2026-01-09&d1=2026-01-09&endDate=2026-01-11&d2=2026-01-11&amenities=POOL) Hot tub [](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel+Cholula%2C+Puebla%2C+Mexico®ionId=553248635640697179&latLong=18.974833%2C-98.385318&adults=2&startDate=2026-01-09&d1=2026-01-09&endDate=2026-01-11&d2=2026-01-11&amenities=HOT_TUB) Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel+Cholula%2C+Puebla%2C+Mexico®ionId=553248635640697179&latLong=18.974833%2C-98.385318&adults=2&startDate=2026-01-09&d1=2026-01-09&endDate=2026-01-11&d2=2026-01-11&amenities=PETS) Apart­ment [](https://www.expedia.ca/Hotel-Search?destination=Santa+Isabel+Cholula%2C+Puebla%2C+Mexico®ionId=553248635640697179&latLong=18.974833%2C-98.385318&adults=2&startDate=2026-01-09&d1=2026-01-09&endDate=2026-01-11&d2=2026-01-11&lodging=APARTMENT) ## Check prices for these dates Tonight [Dec 26 - Dec 27](https://www.expedia.ca/Hotel-Search?regionId=553248635640697179&startDate=2025-12-26&endDate=2025-12-27&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 27 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635640697179&startDate=2025-12-27&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=553248635640697179&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Jan 2 - Jan 4](https://www.expedia.ca/Hotel-Search?regionId=553248635640697179&startDate=2026-01-02&endDate=2026-01-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Cholula-Hotels.d553248635640697179.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FSanta-Isabel-Cholula-Hotels.d553248635640697179.Travel-Guide-Hotels) ### Stay near popular Santa Isabel Cholula attractions [](https://expedia.ca/Puebla-Cathedral-Hotels.0-l6113676-0.Travel-Guide-Filter-Hotels) ![Puebla Cathedral featuring night scenes, heritage architecture and a church or cathedral](https://a.travel-assets.com/findyours-php/viewfinder/images/res70/228000/228611-Puebla-Cathedral.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Puebla Cathedral Listen to the choral performances and appreciate the excellent acoustics of this iconic church. Marvel at the octagonal altar, among other treasures. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6113676) [](https://expedia.ca/University-Of-The-Americas-Puebla-Hotels.0-l553248621555520581-0.Travel-Guide-Filter-Hotels) ![University of the Americas Puebla](https://mediaim.expedia.com/destination/2/6312ef9452396ff561789d5dd0e8f30d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### University of the Americas Puebla Take a campus tour or just explore the area of University of the Americas Puebla, during your trip to San Andrés Cholula. Discover the volcano viewpoints and coffeehouses in this trendy area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=553248621555520581) [](https://expedia.ca/Angelopolis-Commercial-Center-Hotels.0-l6302860-0.Travel-Guide-Filter-Hotels) #### Angelopolis Commercial Center During your visit to Puebla, you can enjoy retail therapy at Angelopolis Commercial Center. Discover the volcano viewpoints in this trendy area. [See properties](https://expedia.ca/Hotel-Search?rfrrid=TG.LP..PointOfInterests®ionId=6302860) ## More cheap stays in Santa Isabel Cholula ![Hotel Sofia](https://images.trvl-media.com/lodging/23000000/22220000/22211400/22211325/137ed512_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Sofia 3 Poniente no 319 Puebla PUE CA $52 CA $62 total Jan 4 - Jan 5, 2026 includes taxes & fees 8.2/10 Very Good! (542 reviews) [](https://expedia.ca/Puebla-Hotels-Hotel-Sofia.h22211325.Hotel-Information) ![Kharma Suites](https://images.trvl-media.com/lodging/30000000/29850000/29849900/29849888/1fb87c26_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Kharma Suites Av. del Castillo 5838 San Andrés Cholula PUE CA $68 CA $81 total Dec 28 - Dec 29 includes taxes & fees 8.8/10 Excellent! (214 reviews) [](https://expedia.ca/Puebla-Hotels-Kharma-Suites.h29849888.Hotel-Information) ![Hotel Teresita](https://images.trvl-media.com/lodging/37000000/36340000/36335700/36335657/1e07a9f8_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Teresita Av 3 Pte 309 Puebla PUE [Get rates](https://expedia.ca/Hotel-Search?startDate=09%2F01%2F2026&endDate=10%2F01%2F2026&selected=36335657&PinnedHotelID=36335657&HadPinnedHotel=true®ionId=553248635640697179) 8.2/10 Very Good! (302 reviews) [](https://expedia.ca/Puebla-Hotels-Hotel-Teresita.h36335657.Hotel-Information) ![Hotel Aroma 406](https://images.trvl-media.com/lodging/38000000/37060000/37058300/37058239/feb8f2d3_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Aroma 406 2 NORTE 406 Puebla PUE [Get rates](https://expedia.ca/Hotel-Search?startDate=09%2F01%2F2026&endDate=10%2F01%2F2026&selected=37058239&PinnedHotelID=37058239&HadPinnedHotel=true®ionId=553248635640697179) 8.4/10 Very Good! (148 reviews) [](https://expedia.ca/Puebla-Hotels-Casa-Hotel-Aroma-406.h37058239.Hotel-Information) ![Hotel Casa Puebla](https://images.trvl-media.com/lodging/121000000/120120000/120110200/120110148/f508337c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Casa Puebla 310 Av 3 Pte Puebla PUE [Get rates](https://expedia.ca/Hotel-Search?startDate=09%2F01%2F2026&endDate=10%2F01%2F2026&selected=120110148&PinnedHotelID=120110148&HadPinnedHotel=true®ionId=553248635640697179) 8/10 Very Good! (22 reviews) [](https://expedia.ca/Puebla-Hotels-Hotel-Casa-Puebla.h120110148.Hotel-Information) ![Hotel Kyoto](https://images.trvl-media.com/lodging/30000000/29320000/29313400/29313362/1175562f_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Kyoto 24 Norte 210-B Puebla PUE [Get rates](https://expedia.ca/Hotel-Search?startDate=09%2F01%2F2026&endDate=10%2F01%2F2026&selected=29313362&PinnedHotelID=29313362&HadPinnedHotel=true®ionId=553248635640697179) 8.4/10 Very Good! (167 reviews) [](https://expedia.ca/Puebla-Hotels-Hotel-Kyoto.h29313362.Hotel-Information) ## Recent reviews of Santa Isabel Cholula hotels ![Quinta Real Puebla](https://images.trvl-media.com/lodging/1000000/30000/21500/21438/c41fbf06_y.jpg) ### Quinta Real Puebla 5/5 Excellent "The staff is helpful and friendly. The room was clean." A verified traveller stayed at Quinta Real Puebla Posted 4 days ago [](https://expedia.ca/Puebla-Hotels-Quinta-Real-Puebla.h21438.Hotel-Information) ![Camino Real Puebla Angelopolis](https://images.trvl-media.com/lodging/4000000/3200000/3192000/3191907/b9d7f344_y.jpg) ### Camino Real Puebla Angelopolis 5/5 Excellent "NA" A verified traveller stayed at Camino Real Puebla Angelopolis Posted 12 days ago [](https://expedia.ca/Puebla-Hotels-Camino-Real-Puebla-Angelopolis.h3191907.Hotel-Information) ![InterContinental Presidente Puebla by IHG](https://images.trvl-media.com/lodging/1000000/50000/46300/46231/78f73717_y.jpg) ### InterContinental Presidente Puebla by IHG 5/5 Excellent "awesome breakfast, great location, beautiful hotel" A verified traveller stayed at InterContinental Presidente Puebla by IHG Posted 3 weeks ago [](https://expedia.ca/Puebla-Hotels-InterContinental-Presidente-Puebla.h46231.Hotel-Information) ![Ramada Encore Puebla Mexico](https://images.trvl-media.com/lodging/17000000/16610000/16608300/16608261/72886336_y.jpg) ### Ramada Encore Puebla Mexico 5/5 Excellent "Good" A verified traveller stayed at Ramada Encore Puebla Mexico Posted 3 weeks ago [](https://expedia.ca/Puebla-Hotels-Ramada-Encore-Puebla-Mexico.h16608261.Hotel-Information) ![Radisson Puebla Angelopolis](https://images.trvl-media.com/lodging/107000000/106210000/106207200/106207119/236a050a_y.jpg) ### Radisson Puebla Angelopolis 5/5 Excellent "Muy bien el hotel " A verified traveller from Chula Vista stayed at Radisson Puebla Angelopolis Posted 3 weeks ago [](https://expedia.ca/Radisson-Hotel-Angelopolis.h106207119.Hotel-Information) ![Four Points By Sheraton Puebla](https://images.trvl-media.com/lodging/22000000/21480000/21472400/21472355/f2d61859_y.jpg) ### Four Points By Sheraton Puebla 5/5 Excellent "Excelente opción para quedarse en Puebla. Limpio, cómodo, tiene un oxxo 24hrs al lado, la ciclovía y bicis en renta. Muy bien" A verified traveller stayed at Four Points By Sheraton Puebla Posted 3 weeks ago [](https://expedia.ca/Puebla-Hotels-Four-Points-By-Sheraton-Puebla.h21472355.Hotel-Information) ![La Quinta by Wyndham Puebla Palmas Angelopolis](https://images.trvl-media.com/lodging/5000000/4840000/4837100/4837004/a13f907c_y.jpg) ### La Quinta by Wyndham Puebla Palmas Angelopolis 5/5 Excellent "Excellent service!! " A verified traveller stayed at La Quinta by Wyndham Puebla Palmas Angelopolis Posted 3 weeks ago [](https://expedia.ca/Puebla-Hotels-La-Quinta-By-Wyndham-Puebla-Palmas-Angelopolis.h4837004.Hotel-Information) ![Hotel Del Portal, Puebla](https://images.trvl-media.com/lodging/2000000/1650000/1649100/1649042/11141d33_y.jpg) ### Hotel Del Portal, Puebla 5/5 Excellent "Staff very nice and friendly " A verified traveller stayed at Hotel Del Portal, Puebla Posted 1 month ago [](https://expedia.ca/Puebla-Hotels-Collection-O-Hotel-Del-Portal.h1649042.Hotel-Information) ![Grand Fiesta Americana Puebla Angelópolis](https://images.trvl-media.com/lodging/14000000/13210000/13205900/13205808/a567bdaa_y.jpg) ### Grand Fiesta Americana Puebla Angelópolis 5/5 Excellent "Great experience starting w good location, friendly staff, everything looks new. Cozy bed, amazing view room 707\. Had breakfast and food was excellent, they even have lactose-free milk 👍" A verified traveller stayed at Grand Fiesta Americana Puebla Angelópolis Posted 1 month ago [](https://expedia.ca/Puebla-Hotels-Grand-Fiesta-Americana-Puebla-Angelopolis.h13205808.Hotel-Information) ## Frequently asked questions ### What's the best place to stay in Santa Isabel Cholula? ### What are some of the best vacation home rentals that Santa Isabel Cholula has to offer? ### If I need to cancel my hotel reservation in Santa Isabel Cholula, will I receive a refund? ### What is staying in Santa Isabel Cholula like? ### What should I see while I'm in Santa Isabel Cholula? ### What's the weather like in Santa Isabel Cholula? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - More ways to book - [4 Star Hotels in Cholula ](https://www.expedia.ca/4Star-Cholula-Puebla-Hotels.s40-n182169-0.Travel-Guide-Filter-Hotels) - [5 Star Hotels in Cholula ](https://www.expedia.ca/5Star-Cholula-Puebla-Hotels.s50-n182169-0.Travel-Guide-Filter-Hotels) - 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