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Hotels near San Diego Santa Fe Depot

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Check prices for these dates

This weekend
Sep 18 - Sep 20
Next weekend
Sep 25 - Sep 27

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Our top choices for San Diego Santa Fe Depot hotels

A hotel room with a herringbone-patterned floor, a bed, a chair, and curtains with room numbers.

1. Stay Classy Hostel

Stay Classy Hostel
2.0 star property
East Village, 1.8 km from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (950 reviews)
"Great, simple stay"
Canada
Wai Kit
The price is CA $64
CA $73 total
includes taxes & fees
Oct 18 - Oct 19
Stay Classy Hostel
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.

2. City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
1.9 km from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (202 reviews)
"The place was really nice and clean. Have a full kitchen, the staff was really kind I love them! For sure we will come back again."
United States
Leriger
The price is CA $161
CA $229 total
includes taxes & fees
Sep 20 - Sep 21
City24 Hotel Little Italy Mission Hills
A rooftop pool with lounge chairs and a city skyline in the background.

3. Kasa Little Italy San Diego

Kasa Little Italy San Diego
4.5 star property
0.4 km from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (526 reviews)
"Definitely would stay again!"
United States
Victor
The price is CA $283
CA $445 total
includes taxes & fees
Sep 21 - Sep 22
Kasa Little Italy San Diego
A living room with a round table, a blue sofa, a patterned armchair, and a potted plant.

4. Crown City Inn

Crown City Inn
2.5 star property
2.7 km from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (839 reviews)
"Excellent stay in every way."
United States
Seth
The price is CA $256
CA $282 total
includes taxes & fees
Sep 27 - Sep 28
Crown City Inn
A modern bedroom with a brick wall, a bed, a desk, and a seating area.

5. Keating Hotel By At Mine Hospitality

Keating Hotel By At Mine Hospitality
2.0 star property
East Village, 1.2 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (173 reviews)
"I really liked it, staff was very friendly"
United States
Seth
The price is CA $62
CA $180 total
includes taxes & fees
Sep 28 - Sep 29
Keating Hotel By At Mine Hospitality
A modern indoor space with a central reflective sculpture, surrounded by planters and a brick wall.

6. Hotel Narcissus

Hotel Narcissus
2.0 star property
2.9 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (37 reviews)
"Very easy to get into and the room was very nice. Great restaurant just downstairs."
United States
Jeffrey
The price is CA $90
CA $242 total
includes taxes & fees
Sep 21 - Sep 22
Hotel Narcissus
A high-rise hotel with multiple floors, a prominent sign at the top, and a well-lit facade.

7. Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
1.1 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1,207 reviews)
"Great for traveling families."
United States
Veronica Dangerfield
The price is CA $264
CA $307 total
includes taxes & fees
Sep 27 - Sep 28
Marriott Vacation Club®, San Diego
A spacious dining area with high ceilings, large chandeliers, and a modern interior design.

8. Pendry San Diego

Pendry San Diego
5.0 star property
Gaslamp Quarter, 1.2 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1,002 reviews)
"Great place to stay! Worth the price for the location and luxury."
United States
Melinda
The price is CA $441
CA $588 total
includes taxes & fees
Oct 14 - Oct 15
Pendry San Diego
A restaurant with outdoor seating, brick walls, and decorative lighting.

9. The Horton Grand, Downtown/Gaslamp Quarter

The Horton Grand, Downtown/Gaslamp Quarter
3.5 star property
1 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (2,948 reviews)
"Love this historic hotel"
United States
Ruben
The price is CA $214
CA $287 total
includes taxes & fees
Sep 27 - Sep 28
The Horton Grand, Downtown/Gaslamp Quarter
A rooftop lounge with a view of the city and ocean, featuring a sofa, chairs, and round tables.

10. Springhill Suites San Diego Downtown/Bayfront

Springhill Suites San Diego Downtown/Bayfront
3.5 star property
0.2 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (1,032 reviews)
"Great stay"
United States
Bonnie
The price is CA $312
CA $362 total
includes taxes & fees
Oct 7 - Oct 8
Springhill Suites San Diego Downtown/Bayfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to San Diego Santa Fe Depot

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A hotel room with a herringbone-patterned floor, a bed, a chair, and curtains with room numbers.
Stay Classy Hostel
2.0 star property
9.6
Exceptional
950 reviews
View
A narrow, enclosed walkway with wooden railings and a metal grid barrier, leading to a building entrance.
City24 Hotel Little Italy Mission Hills
4.5 star property
9.6
Exceptional
202 reviews
View
A rooftop pool with lounge chairs and a city skyline in the background.
Kasa Little Italy San Diego
4.5 star property
9.6
Exceptional
526 reviews
View
A living room with a round table, a blue sofa, a patterned armchair, and a potted plant.
Crown City Inn
2.5 star property
9.6
Exceptional
839 reviews
View
A modern bedroom with a brick wall, a bed, a desk, and a seating area.
Keating Hotel By At Mine Hospitality
2.0 star property
9.4
Exceptional
173 reviews
View

Top San Diego Santa Fe Depot Hotel Reviews

The Alcala Hotel Mission Valley/Seaworld

The Alcala Hotel Mission Valley/Seaworld

10/10 Excellent
"Really enjoyed stay. Nice room, pleasant staff. Would definitely stay again."
David 1-night trip
Posted 6 hours ago
The Alcala Hotel Mission Valley/Seaworld

Frequently asked questions

What's the area like around San Diego Santa Fe Depot?

San Diego Santa Fe Depot is located in a scenic area of San Diego known for its array of dining options and popular zoo. If you're looking for a convenient place to stay, check out the 925 hotels and other accommodations located within a mile of the station.

What's the best hotel to stay close to San Diego Santa Fe Depot?

Adjacent to San Diego Santa Fe Depot, Wyndham San Diego Bayside is one of the top choices for your stay based on our traveler data, and this hotel offers 3 restaurants and an outdoor pool. Other good options close by include Manchester Grand Hyatt San Diego and Hard Rock Hotel San Diego.

How many hotels will I find close to San Diego Santa Fe Depot?

Expedia has 925 hotels and other accommodations within a mile from the station.

What can I see and do near San Diego Santa Fe Depot?

Study the collections at USS Midway Museum, Maritime Museum of San Diego, or San Diego Air and Space Museum. Hotel del Coronado, Star of India, and Our Lady of the Rosary Catholic Church are monuments to see when you're exploring the area around San Diego Santa Fe Depot. You can watch performances at San Diego Civic Theatre, The Rady Shell at Jacobs Park, and Humphreys Concerts by the Bay if you're interested in local theater.

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