Hotels near San Diego Santa Fe Depot

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for San Diego Santa Fe Depot hotels

Springhill Suites San Diego Downtown/Bayfront

Springhill Suites San Diego Downtown/Bayfront
3.5 star property
0.2 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (1,003 reviews)
"Great Location, nice hotel, Friendly Staff."
United States
Gary F
The price is CA $283
CA $328 total
includes taxes & fees
Jun 8 - Jun 9
Springhill Suites San Diego Downtown/Bayfront

Residence Inn by Marriott San Diego Downtown/Bayfront

Residence Inn by Marriott San Diego Downtown/Bayfront
3.0 star property
0.2 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (664 reviews)
"I will definitely stay there again !"
United States
Diana
The price is CA $355
CA $412 total
includes taxes & fees
May 28 - May 29
Residence Inn by Marriott San Diego Downtown/Bayfront

Hotel Z

Hotel Z
3.0 star property
Gaslamp Quarter, 1.1 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1,003 reviews)
"Friendly staff, clean room, very quiet! Enjoyed our stay! "
United States
Jayda
The price is CA $158
CA $231 total
includes taxes & fees
May 27 - May 28
Hotel Z

The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel

The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
4.0 star property
0.1 km from San Diego Santa Fe Depot
9.0 out of 10, Wonderful, (1,152 reviews)
"Very nice cute hotel. Wonderful experience."
United States
Rondelle
The price is CA $232
CA $269 total
includes taxes & fees
May 25 - May 26
The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel

Hotel Republic San Diego, Autograph Collection

Hotel Republic San Diego, Autograph Collection
4.0 star property
0.3 km from San Diego Santa Fe Depot
9.0 out of 10, Wonderful, (1,180 reviews)
"Great location! Well maintained hotel. Good staff!"
United States
Helena
The price is CA $213
CA $311 total
includes taxes & fees
May 26 - May 27
Hotel Republic San Diego, Autograph Collection

Westgate Hotel

Westgate Hotel
4.5 star property
0.6 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (1,003 reviews)
"Beautiful and very clean hotel! Would definitely stay again!"
United States
Nancy
The price is CA $214
CA $295 total
includes taxes & fees
May 25 - May 26
Westgate Hotel

Stay Classy Hostel

Stay Classy Hostel
2.0 star property
1.8 km from San Diego Santa Fe Depot
9.6 out of 10, Exceptional, (853 reviews)
"Clean, secure, easy to stay, good location"
United States
Travis
The price is CA $78
CA $89 total
includes taxes & fees
May 26 - May 27
Stay Classy Hostel

City24 Hotel Little Italy Mission Hills

City24 Hotel Little Italy Mission Hills
4.5 star property
1.9 km from San Diego Santa Fe Depot
9.8 out of 10, Exceptional, (151 reviews)
"Beautiful fully appointed rooms and excellent location."
United States
Michelle
The price is CA $206
CA $279 total
includes taxes & fees
May 20 - May 21
City24 Hotel Little Italy Mission Hills

Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina
4.0 star property
0.9 km from San Diego Santa Fe Depot
9.2 out of 10, Wonderful, (2,123 reviews)
"Excellent stay!"
United States
Joyce
The price is CA $295
CA $407 total
includes taxes & fees
May 22 - May 23
Marriott Marquis San Diego Marina

Marriott Vacation Club®, San Diego

Marriott Vacation Club®, San Diego
3.5 star property
1.1 km from San Diego Santa Fe Depot
9.4 out of 10, Exceptional, (1,078 reviews)
"The hotel was very clean and had very friendly staff. Location was amazing."
United States
Brenda
The price is CA $221
CA $256 total
includes taxes & fees
May 28 - May 29
Marriott Vacation Club®, San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Compare popular hotels close to San Diego Santa Fe Depot

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
Outdoor pool, pool umbrellas, sun loungers
Springhill Suites San Diego Downtown/Bayfront
3.5 star property
9.2
Wonderful
1,003 reviews
View
View from property
Residence Inn by Marriott San Diego Downtown/Bayfront
3.0 star property
9.2
Wonderful
664 reviews
View
Premium bedding, pillowtop beds, desk, laptop workspace
Hotel Z
3.0 star property
9.4
Exceptional
1,003 reviews
View
Terrace/patio
The Guild Hotel, San Diego Downtown, a Marriott Tribute Portfolio Hotel
4.0 star property
9.0
Wonderful
1,152 reviews
View
Lobby
Hotel Republic San Diego, Autograph Collection
4.0 star property
9.0
Wonderful
1,180 reviews
View

Top San Diego Santa Fe Depot Hotel Reviews

Frequently asked questions

What's the area like around San Diego Santa Fe Depot?

San Diego Santa Fe Depot is located in a scenic area of San Diego known for its array of dining options and popular zoo. If you're looking for a convenient place to stay, check out the 906 hotels and other accommodations located within a mile of the station.

What's the best hotel to stay close to San Diego Santa Fe Depot?

Adjacent to San Diego Santa Fe Depot, The Sofia Hotel is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and a 24-hour fitness center. Other good options close by include Hard Rock Hotel San Diego and The DEXTRO Little Italy, BW Premier Collection.

How many hotels will I find close to San Diego Santa Fe Depot?

Expedia has 906 hotels and other accommodations within a mile from the station.

What can I see and do near San Diego Santa Fe Depot?

Study the collections at USS Midway Museum, Maritime Museum of San Diego, or San Diego Air and Space Museum. Hotel del Coronado, Our Lady of the Rosary Catholic Church, and Whaley House Museum are monuments to see when you're exploring the area around San Diego Santa Fe Depot. You can watch performances at San Diego Civic Theatre, The Rady Shell at Jacobs Park, and Humphreys Concerts by the Bay if you're interested in local theater.

Explore a world of travel with Expedia