Title: Book the Best Patagonia SPA Resorts from CA $203 - Spa Hotels in Patagonia, AZ | Expedia.ca [Hotels in Patagonia](https://expedia.ca/Patagonia-Hotels.d143941.Travel-Guide-Hotels)[Vacation Rentals in Patagonia](https://expedia.ca/Patagonia-Vacation-Rentals.d143941.Travel-Guide-VacationRentals)[Flights to Patagonia](https://expedia.ca/Cheap-Flights-To-Patagonia.d143941.Travel-Guide-Flights)[Patagonia Car Rentals](https://expedia.ca/Car-Rentals-In-Patagonia.d143941.Car-Rental-Guide)[Patagonia Vacation Packages](https://expedia.ca/Patagonia.d143941.Destination-Travel-Guides) ![](https://mediaim.expedia.com/destination/1/953bea84bd65dd5b8e4b1c07ccfd2edf.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Spa Hotels in Patagonia, AZ from CA $203 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Patagonia Spa Hotels Tonight [Nov 2 - Nov 3](https://www.expedia.ca/Hotel-Search?regionId=143941&startDate=2025-11-02&endDate=2025-11-03&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Nov 3 - Nov 4](https://www.expedia.ca/Hotel-Search?regionId=143941&startDate=2025-11-03&endDate=2025-11-04&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Nov 7 - Nov 9](https://www.expedia.ca/Hotel-Search?regionId=143941&startDate=2025-11-07&endDate=2025-11-09&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Nov 14 - Nov 16](https://www.expedia.ca/Hotel-Search?regionId=143941&startDate=2025-11-14&endDate=2025-11-16&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Patagonia Spa Hotels ![Exterior](https://images.trvl-media.com/lodging/1000000/870000/861000/860989/6913b491.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/870000/861000/860989/32143a5b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free buffet breakfast](https://images.trvl-media.com/lodging/1000000/870000/861000/860989/b95a0e2a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Double Room, 2 Double Beds, Non Smoking](https://images.trvl-media.com/lodging/1000000/870000/861000/860989/be0529ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Comfort Inn Green Valley I-19 Tucson Green Valley 8.2/10 Very good (614) "It was a perfect location for my need I do not like having to review every hotel that comes along. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tyrus CA $181 CA $203 total includes taxes & fees Nov 29 - Nov 30 [](https://www.expedia.ca/Tucson-Hotels-Comfort-Inn-Green-Valley-I-19.h860989.Hotel-Information) ![Couples treatment rooms, sauna, hot tub, steam room, body treatments](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353844/65187603.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353844/5683d211.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353844/595f3662.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![2 outdoor pools, open 6:00 AM to 9:00 PM, free cabanas, pool umbrellas](https://images.trvl-media.com/lodging/2000000/1360000/1353900/1353844/cc540676.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tubac Golf Resort & Spa Tubac 9.4/10 Exceptional (446) "Such a Beautiful place and comfortable casita. Restaurant was amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Heidi CA $443 CA $510 total includes taxes & fees Nov 12 - Nov 13 [](https://www.expedia.ca/Nogales-Hotels-Tubac-Golf-Resort-Spa.h1353844.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-11-16&endDate=2025-11-17®ionId=143941&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Top Patagonia Hotel Reviews ![Clarion Inn](//images.trvl-media.com/lodging/1000000/50000/42100/42012/df2fd5c5_y.jpg) ### Clarion Inn 10/10 Excellent "I was very impressed by the staff and the service. " [](https://expedia.ca/Sierra-Vista-Hotels-Sierra-Suites.h42012.Hotel-Information) ![Holiday Inn Express Sierra Vista by IHG](//images.trvl-media.com/lodging/2000000/1650000/1640100/1640090/aacf0797_y.jpg) ### Holiday Inn Express Sierra Vista by IHG 10/10 Excellent "Friendly staff, clean room, good location. " [](https://expedia.ca/Sierra-Vista-Hotels-Holiday-Inn-Express-Sierra-Vista.h1640090.Hotel-Information) ![Comfort Inn Green Valley I-19](//images.trvl-media.com/lodging/1000000/870000/861000/860989/6913b491_y.jpg) ### Comfort Inn Green Valley I-19 10/10 Excellent "Rooms were fine. AC didnt seem to keep the room thaat cool. Staff was friendly and pleasant. Breakfast was typical, needed to be hotter and better food. " [](https://expedia.ca/Tucson-Hotels-Comfort-Inn-Green-Valley-I-19.h860989.Hotel-Information) ![Best Western Green Valley Inn](//images.trvl-media.com/lodging/1000000/40000/34100/34091/bd0f1f19_y.jpg) ### Best Western Green Valley Inn 10/10 Excellent "Great hotel but a bummer the hot tub was down." [](https://expedia.ca/Tucson-Hotels-Best-Western-Green-Valley-Inn.h34091.Hotel-Information) ![Best Western Plus Sun Canyon](//images.trvl-media.com/lodging/6000000/5790000/5780700/5780601/bcbe294a_y.jpg) ### Best Western Plus Sun Canyon 10/10 Excellent "Other than the road construction, the hotel was quiet and clean." [](https://expedia.ca/Sierra-Vista-Hotels-Best-Western-Plus-Sun-Canyon.h5780601.Hotel-Information) ![Vagabond Inn Executive - Green Valley](//images.trvl-media.com/lodging/1000000/70000/64300/64233/d4a68901_y.jpg) ### Vagabond Inn Executive - Green Valley 10/10 Excellent "Nice" [](https://expedia.ca/Tucson-Hotels-Vagabond-Inn-Executive-Green-Valley.h64233.Hotel-Information) ![Gateway Studio Suites](//images.trvl-media.com/lodging/5000000/4860000/4857100/4857074/682aee0c_y.jpg) ### Gateway Studio Suites 10/10 Excellent "The rooms were clean, spacious with lots of places to sit and the bed was comfortable. The neighborhood was quiet and not far from shopping. The staff was friendly, will definitely stay there again. " [](https://expedia.ca/Sierra-Vista-Hotels-Gateway-Studio-Suites.h4857074.Hotel-Information) ![Best Western Sonora Inn & Suites](//images.trvl-media.com/lodging/3000000/2970000/2963300/2963257/c4d8d9a5_y.jpg) ### Best Western Sonora Inn & Suites 10/10 Excellent "Wonderful service and very well kept hotel. Comfortable beds. Very clean and modern. We were here 5 years ago and the hotel has not aged at all. Special thanks to Jose at the front desk for helping us out with printing our documents. " [](https://expedia.ca/Nogales-Hotels-Best-Western-Sonora-Inn-Suites.h2963257.Hotel-Information) ## Frequently asked questions ### Looking for a spa hotel in Patagonia? > Book one of our fantastic spa hotels and treat yourself from the moment you arrive. Check out the musical theater scene in Patagonia—your cultural tour starts here. Be sure to enjoy activities like horseback riding and fishing during your stay. Hotels with spas are the perfect way to break away from your routine and add a layer of luxury to your vacation. ### What's there to see and do in Patagonia? > Enjoy Patagonia and visit Paton's Hummingbird Haven, Patagonia-Sonoita Creek Preserve, and Mount Wrightson Wilderness. If you have some spare time during your trip, you might want to check out Patagonia Lake State Park and Santa Cruz County Fairgrounds. ### What is a Patagonia spa hotel? > Spa hotels in Patagonia have full on-site spas which offer services like facials and a selection of beauty treatments. Some also provide a selection of in-room treatments for the ultimate luxury. 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