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Panama Vacation Rentals

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Check prices for these dates

In two weeks
Sep 18 - Sep 20
In two months
Oct 30 - Nov 1
In three months
Nov 27 - Nov 29
In four months
Dec 25 - Dec 27

Our top choices for Panama vacation rentals

A two-story house with a front porch, a green door, and the number 408 on the right side.

1. Harrison House; Litchfield, IL; Pets welcome

Harrison House; Litchfield, IL; Pets welcome
Litchfield
10.0 out of 10, Exceptional, (21 reviews)
"Loved this property. Will def be staying again. "
United States
Amanda G.
The price is CA $176
CA $276 total
includes taxes & fees
Sep 7 - Sep 8
Harrison House; Litchfield, IL; Pets welcome
A living room with a black leather couch, a wooden coffee table, and a bookshelf. There is a dining area visible through an archway with a wooden table and chairs.

2. State Street House; 3-br house; PETS WELCOME; Litchfield

State Street House; 3-br house; PETS WELCOME; Litchfield
Litchfield
9.4 out of 10, Exceptional, (16 reviews)
"Perfect location! Everything was great!"
United States
Kelly C.
The price is CA $256
CA $392 total
includes taxes & fees
Sep 7 - Sep 8
State Street House; 3-br house; PETS WELCOME; Litchfield
A modern kitchen with white cabinets, a gas stove, and a microwave. There is a dining area with a wooden table and two chairs.

3. Edwards House; Litchfield, IL; Pets welcome

Edwards House; Litchfield, IL; Pets welcome
Litchfield
10.0 out of 10, Exceptional, (28 reviews)
"Very cozy, cute house!"
United States
Star
The price is CA $165
CA $255 total
includes taxes & fees
Sep 7 - Sep 8
Edwards House; Litchfield, IL; Pets welcome
A modern kitchen with granite countertops, stainless steel appliances, and decorative wall shelves.

4. Tiny Cabin in the Woods - Firepit - just off I-70 - Pets Welcome!

Tiny Cabin in the Woods - Firepit - just off I-70 - Pets Welcome!
Mulberry Grove
9.8 out of 10, Exceptional, (35 reviews)
"Went to visit kids who live in the area. Normally we get a hotel but decided to try doing something different. This was so much better than hotels and plan to go back next time we are down."
United States
Julie
The price is CA $131
CA $263 total
includes taxes & fees
Sep 7 - Sep 8
Tiny Cabin in the Woods - Firepit - just off I-70 - Pets Welcome!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Panama Hotel Reviews

Super 8 by Wyndham Greenville

Super 8 by Wyndham Greenville

8/10 Good
"Small bathroom, but decent size bedroom. Bed was soft and comfortable. Everything was very clean!! Considering we just needed a place to sleep for 1 night while traveling across several states, it was a good place to stay for the price."
Kristen 1-night trip
Posted 19 hours ago
Super 8 by Wyndham Greenville

Find out more about Panama

Everything you need to know about Panama vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Panama vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Panama vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Panama vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Panama. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Panama vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Panama vacation rentals we have selected for you start as low as CA $255 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Panama rentals

At Expedia, we put the best Panama vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Panama rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Panama vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Panama. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Are there vacation rentals in Panama?

Yes, there are vacation rentals close to popular points of interest in Panama, or you can select a more secluded option if you're looking for a relaxing stay.

What are some of the best vacation rentals in Panama?

Edwards House; Litchfield, IL; Pets welcome: This vacation home rental near Panama offers a patio, a private yard, and air-conditioning to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop, and a microwave.

What can I see and do in Panama?

While you're exploring the area, Lake Lou Yeager and Walton Park are a couple of picturesque spots to get outside and enjoy nature. In the larger area, you’ll find Patriot's Park and Greenville Country Club.

What are vacation rentals like in Panama?

Vacation rentals are privately owned accommodations you can stay in for a few days or a quick weekend in Panama. Vacation rentals provide amenities like WiFi and washers and dryers so you'll have everything you need. If you're concerned about cleanliness, a vacation rental can provide a sense of privacy away from shared hotel elevators and lobbies packed with people while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a traditional hotel, which makes a vacation rental an attractive option for family trips or small group gatherings.