Title: Nuevo Santiago Vacation Rentals from CA $143: Short-Term Rentals for 2026 | Expedia.ca

[Nuevo Santiago Travel Guide](https://expedia.ca/Nuevo-Santiago.dx829297296863682560)[Hotels in Nuevo Santiago](https://expedia.ca/Nuevo-Santiago-Hotels.d829297296863682560.Travel-Guide-Hotels)[Nuevo Santiago Car Rentals](https://expedia.ca/Car-Rentals-In-Nuevo-Santiago.d829297296863682560.Car-Rental-Guide)[Nuevo Santiago Vacation Packages](https://expedia.ca/Nuevo-Santiago.d829297296863682560.Destination-Travel-Guides)

![360 aerial photo taken with drone of Parque Nacional Altos de Campana National Park in Panamá](https://images.trvl-media.com/place/829297296863682560/f8408964-174a-4efe-9d59-b812a975ddd4.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

![](https://images.trvl-media.com/place/829297296863682560/f8408964-174a-4efe-9d59-b812a975ddd4.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Apr 17 - Apr 19](https://www.expedia.ca/Hotel-Search?regionId=829297296863682560&startDate=2026-04-17&endDate=2026-04-19&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 29 - May 31](https://www.expedia.ca/Hotel-Search?regionId=829297296863682560&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[Jun 26 - Jun 28](https://www.expedia.ca/Hotel-Search?regionId=829297296863682560&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jul 24 - Jul 26](https://www.expedia.ca/Hotel-Search?regionId=829297296863682560&startDate=2026-07-24&endDate=2026-07-26&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Nuevo Santiago vacation rentals

![Beach](https://images.trvl-media.com/lodging/126000000/125160000/125156600/125156525/bc379b20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior](https://images.trvl-media.com/lodging/126000000/125160000/125156600/125156525/525d00c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Private kitchen](https://images.trvl-media.com/lodging/126000000/125160000/125156600/125156525/9f57b914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Internet](https://images.trvl-media.com/lodging/126000000/125160000/125156600/125156525/df462606.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Perfect 1-bedroom bungalow with AC in peaceful Playa reina

[](https://www.expedia.ca/Canto-Del-Llano-Hotels-Perfect-1-Bedroom-Bungalow-With-AC-In-Peaceful-Playa-Reina.h125156525.Hotel-Information)

Santiago

CA $94

CA $143 total

includes taxes & fees

Apr 15 - Apr 16

[](https://www.expedia.ca/Canto-Del-Llano-Hotels-Perfect-1-Bedroom-Bungalow-With-AC-In-Peaceful-Playa-Reina.h125156525.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.ca/Hotel-Search?startDate=2026-04-15&endDate=2026-04-16&regionId=829297296863682560&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

## Find vacation rentals that suit your style

Private vacation homes

[](https://www.expedia.ca/Hotel-Search?destination=Nuevo+Santiago%2C+Veraguas%2C+Panama&regionId=829297296863682560&latLong=8.100265%2C-80.92691&adults=2&startDate=2026-06-30&d1=2026-06-30&endDate=2026-07-03&d2=2026-07-03&lodging=VACATION_HOME)

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## Top Nuevo Santiago Hotel Reviews

![Hotel Galería](https://images.trvl-media.com/lodging/28000000/27580000/27570800/27570722/7a530baa_y.jpg)

### Hotel Galería

8/10 Good

"Called the property several t times with no answer. When we arrived the young man was on duty. He did everything he could to assist us. In the evening the gal on duty was very dismissive, couldn't even arrange for a taxi. The restaurant was very good and tasty, and the wait staff was excellent! I'd stay there again if I was in the city."

[](https://expedia.ca/Santiago-Hotels-Hotel-Galeria.h27570722.Hotel-Information)

![Hotel Gran David](https://images.trvl-media.com/lodging/13000000/12010000/12003400/12003378/bb11ab13_y.jpg)

### Hotel Gran David

10/10 Excellent

"Parquing accesible, las instalaciones impecables, personal amable y buen desayuno. El área de piscina es muy agradable. "

[](https://expedia.ca/Santiago-Hotels-Hotel-Gran-David.h12003378.Hotel-Information)

![Hotel Mykonos Panama](https://images.trvl-media.com/lodging/6000000/5280000/5270400/5270392/1db3bbb0_y.jpg)

### Hotel Mykonos Panama

10/10 Excellent

"People were helpful. Good ambiance to eat around the pool place "

[](https://expedia.ca/Santiago-Hotels-Hotel-Mykonos-Panama.h5270392.Hotel-Information)

![HOTEL VISTA LAGO](https://images.trvl-media.com/lodging/96000000/95680000/95675300/95675257/34474832_y.jpg)

### HOTEL VISTA LAGO

10/10 Excellent

"Great place to stay for the night :) pretty setting, spacious clean rooms, yummy restaurant, friendly and helpful staff. Great value. Highly recommend."

[](https://expedia.ca/Nuevo-Santiago-Hotels-HOTEL-VISTA-LAGO.h95675257.Hotel-Information)

## Find out more about Nuevo Santiago

You always said you would go on a dream vacation someday. Now, someday is here. But you don’t just want to dip your toe into the trip of a lifetime, you want to cannon ball into the deep end. Go ahead, unplug and unwind in style. When you book one of our vacation rentals, the ordinary is in the rearview. Instead of sharing your vacation with hundreds of hotel guests, you get to take advantage of all the space at your private apartment or room. You also get to enjoy all the amenities of a private residence for a truly unique and memorable stay. Why don’t you take off your shoes and settle in for a while? Your vacation just got upgraded.  
  
As much as you love your short-term rental, it’s always good to get out and explore to soak up . Live like a local: Eat regional food, cheer on the home team, and visit the best cultural attractions in town. No matter the season, there is always something going on in . Seeing all the best attractions is bound to make you fall in love with Nuevo Santiago. Who knows, you may even be tempted to extend your vacation rental stay. There’s a reason home rentals are so popular here—after a long day of exploration, going back to your very own living room to stretch out is a dream come true.   
  
It’s your escape so why share it? You deserve your own slice of paradise. Booking your vacation rental on Expedia is simple and safe. Just pick your dates to search for the perfect property and book securely. We let you contact the property owner directly to make any special arrangements. All that’s left to do is show up with bells on and have a memorable vacation. With all the amenities available in short-term rentals, that won’t be hard to do.   

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## Frequently asked questions

### Can I find a vacation rental in Nuevo Santiago?

### What are some of the best vacation home rentals in Nuevo Santiago?

### What can I see and do in Nuevo Santiago?

### What are vacation rentals like in Nuevo Santiago?

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Flights

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Activities

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General

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