Title: Hotels by Best Western in Mebane | Expedia.ca [Mebane Travel Guide](https://expedia.ca/Mebane.dx180961)[Hotels in Mebane](https://expedia.ca/Mebane-Hotels.d180961.Travel-Guide-Hotels)[Vacation Rentals in Mebane](https://expedia.ca/Mebane-Vacation-Rentals.d180961.Travel-Guide-VacationRentals)[Flights to Mebane](https://expedia.ca/Cheap-Flights-To-Mebane.d180961.Travel-Guide-Flights)[Mebane Car Rentals](https://expedia.ca/Car-Rentals-In-Mebane.d180961.Car-Rental-Guide)[Mebane Vacation Packages](https://expedia.ca/Mebane.d180961.Destination-Travel-Guides) ![Farm surrounded by a harvested field](https://images.trvl-media.com/place/180961/5f702896-f7fc-45a7-9280-3872f62bf7f7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/180961/5f702896-f7fc-45a7-9280-3872f62bf7f7.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 10 - Mar 11](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2026-03-10&endDate=2026-03-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 11 - Mar 12](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2026-03-11&endDate=2026-03-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=180961&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FMebane-Hotels-Best-Western.0-0-d180961--bBestWestern.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FMebane-Hotels-Best-Western.0-0-d180961--bBestWestern.Travel-Guide-Filter-Hotels) ## Top Mebane Hotel Reviews ![University Inn Durham next to Duke University Medical Center](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/80e8b722_y.jpg) ### University Inn Durham next to Duke University Medical Center 10/10 Excellent "Solid & affordable choice, close to the hospital and clinics." [](https://expedia.ca/Raleigh-Hotels-University-Inn-Durham-Next-To-Duke-University-Medical-Center.h1464431.Hotel-Information) ![Comfort Inn & Suites Durham near Duke University](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/22181a04_y.jpg) ### Comfort Inn & Suites Durham near Duke University 8/10 Good "Was here to have surgery. The room was smaller than photoed I got the room with the sofa bed in case we needed spare bed, to not bother my hubby. The water pressure on 5th floor was weak at best. But the staff was so friendly and helpful. I reported my few issues to the checkout clerk and otherwise would and likely will stay here again. " [](https://expedia.ca/Raleigh-Hotels-Comfort-Inn-Suites-Durham-Near-Duke-University.h12352.Hotel-Information) ![La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill](https://images.trvl-media.com/lodging/1000000/170000/165800/165760/adc70ef4_y.jpg) ### La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill 8/10 Good "Bathroom paint job was messy. Tub can be updated." [](https://expedia.ca/Raleigh-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Univ-Area-Chapel-Hill.h165760.Hotel-Information) ![Holiday Inn Express Hotel & Suites Mebane by IHG](https://images.trvl-media.com/lodging/1000000/910000/904300/904203/91425190_y.jpg) ### Holiday Inn Express Hotel & Suites Mebane by IHG 8/10 Good "My room was great very clean" [](https://expedia.ca/Mebane-Hotels-Holiday-Inn-Express-Hotel-Suites-Mebane.h904203.Hotel-Information) ![Millennium Durham](https://images.trvl-media.com/lodging/1000000/30000/26400/26351/d527d5cf_y.jpg) ### Millennium Durham 8/10 Good "Clean place, bad cell service inside." [](https://expedia.ca/Raleigh-Hotels-Millennium-Durham.h26351.Hotel-Information) ![DoubleTree Suites by Hilton Raleigh - Durham](https://images.trvl-media.com/lodging/1000000/20000/13200/13139/w3840h2557x0y0-f360c06d_y.jpg) ### DoubleTree Suites by Hilton Raleigh - Durham 10/10 Excellent "Very nice" [](https://expedia.ca/Raleigh-Hotels-DoubleTree-Suites-By-Hilton-Raleigh-Durham.h13139.Hotel-Information) ![Candlewood Suites Durham by IHG](https://images.trvl-media.com/lodging/1000000/530000/528800/528739/ab636bce_y.jpg) ### Candlewood Suites Durham by IHG 10/10 Excellent "Gym, free laundry service, free parking and kitchen " [](https://expedia.ca/Raleigh-Hotels-Candlewood-Suites-Durham.h528739.Hotel-Information) ![Aloft Chapel Hill](https://images.trvl-media.com/lodging/4000000/3490000/3486700/3486607/3a1127c6_y.jpg) ### Aloft Chapel Hill 10/10 Excellent "Aloft in Chapel Hill Saved Our Trip!! We actually had booked at a different hotel for our short visit to Chapel Hill and it was gross, smelled terrible, and was a little scary just to be honest. So we quickly checked right back out and found ALOFT - Thank Goodness!!! From the second I walked in the lobby door I felt at home and welcomed! Staff is friendly, helpful and just plain fantastic with my every question and request. The entire hotel had the most wonderful clean fragrance. The room was just what we needed, clean and again had a nice clean fragrance. On site gym was very nice. And the lobby lounge area had a great fun/homey atmosphere where everyone could feel comfortable. Will definitely stay again if we visit Chapel Hill!!! " [](https://expedia.ca/Raleigh-Hotels-Aloft-Chapel-Hill.h3486607.Hotel-Information) ![Hilton Durham near Duke University](https://images.trvl-media.com/lodging/1000000/20000/18900/18821/aa0fe1f8_y.jpg) ### Hilton Durham near Duke University 10/10 Excellent "My stay was great. Thx to all" [](https://expedia.ca/Raleigh-Hotels-Hilton-Durham-Near-Duke-University.h18821.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - More ways to book - [Motel 6 Hotels in Aberdeen ](https://www.expedia.ca/Aberdeen-Hotels-Motel-6.0-0-d5955--bMotel6.Travel-Guide-Filter-Hotels) - [Hilton Hotels in Bahama ](https://www.expedia.ca/Bahama-Hotels-Hilton-Hotels.0-0-d6320162--bHiltonHotels.Travel-Guide-Filter-Hotels) - [Marriott Hotels & Resorts in Benson ](https://www.expedia.ca/Benson-Hotels-Marriott-Hotels-Resorts.0-0-d6742--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels) - [B&B in Burlington ](https://www.expedia.ca/Burlington-Bed-And-Breakfast.d6234-aaBedAndBreakfast.Travel-Guide-Accommodation) - [Guest Houses in Burlington ](https://www.expedia.ca/Burlington-Guest-Houses.d6234-aaGuestHouses.Travel-Guide-Accommodation) - [Boutique Hotels in Burlington ](https://www.expedia.ca/Burlington-Hotels-Boutique-Hotel.0-0-d6234-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - 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