The best area to stay in Madre de Dios is Puerto Maldonado, as it's the regional capital and the primary gateway to the Amazon rainforest.
Puerto Maldonado is where most visitors will arrive, either by plane or bus. The city itself is a bustling hub, situated at the confluence of the Tambopata and Madre de Dios rivers. You'll find the main market, banks, and a variety of local restaurants along the main streets like Avenida León Velarde. It serves as the base for all jungle excursions.
For travellers looking for a comfortable stay before or after their jungle adventure, hotels within Puerto Maldonado's town centre are ideal. They offer convenience, with easy access to the airport and river ports. Many hotels provide amenities like air conditioning and swimming pools, which are welcome after a day in the tropical heat.
For those prioritising a direct jungle experience, lodges located along the rivers outside of Puerto Maldonado are the best option. These lodges offer immediate access to the rainforest, with activities like guided walks, boat trips, and wildlife spotting.