Title: Book The Best Hotels in La Mesa for 2026 from CA $46 - Fully Refundable Options - Expedia.ca [Vacation Rentals in La Mesa](https://expedia.ca/La-Mesa-Vacation-Rentals.d553248635976270713.Travel-Guide-VacationRentals)[La Mesa Car Rentals](https://expedia.ca/Car-Rentals-In-La-Mesa.d553248635976270713.Car-Rental-Guide)[La Mesa Vacation Packages](https://expedia.ca/La-Mesa.d553248635976270713.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Go beyond your typical stay in La Mesa Pet friendly [](https://www.expedia.ca/Hotel-Search?destination=La+Mesa%2C+Zapotl%C3%A1n+el+Grande%2C+Jalisco%2C+Mexico®ionId=553248635976270713&latLong=19.628659%2C-103.510988&adults=2&startDate=2026-03-23&d1=2026-03-23&endDate=2026-03-25&d2=2026-03-25&amenities=PETS) ## Check prices for these dates Tonight [Mar 9 - Mar 10](https://www.expedia.ca/Hotel-Search?regionId=553248635976270713&startDate=2026-03-09&endDate=2026-03-10&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 10 - Mar 11](https://www.expedia.ca/Hotel-Search?regionId=553248635976270713&startDate=2026-03-10&endDate=2026-03-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 13 - Mar 15](https://www.expedia.ca/Hotel-Search?regionId=553248635976270713&startDate=2026-03-13&endDate=2026-03-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 20 - Mar 22](https://www.expedia.ca/Hotel-Search?regionId=553248635976270713&startDate=2026-03-20&endDate=2026-03-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for La Mesa hotels ![Loft](https://images.trvl-media.com/lodging/115000000/114160000/114153800/114153710/8a731937.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114160000/114153800/114153710/4dccf33f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Loft](https://images.trvl-media.com/lodging/115000000/114160000/114153800/114153710/b6d93b3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/115000000/114160000/114153800/114153710/91922d41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lofts Independencia Sayula [](https://www.expedia.ca/Sayula-Hotels-Lofts-Independencia-Sayula.h114153710.Hotel-Information) Sayula 5.4/10 (6 reviews) "Not satisfied charges for parking, pool and needed to ask for fresh towels n toilet paper no AC" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) ARTURO CA $47 CA $57 total includes taxes & fees Mar 10 - Mar 11 [](https://www.expedia.ca/Sayula-Hotels-Lofts-Independencia-Sayula.h114153710.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/49000000/48710000/48709600/48709526/a8b0d54c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Standard Triple Room | View from room](https://images.trvl-media.com/lodging/49000000/48710000/48709600/48709526/86c6c882.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/49000000/48710000/48709600/48709526/7dd4c51e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/49000000/48710000/48709600/48709526/15e8a106.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Capital O Colón, Ciudad Guzmán Jalisco [](https://www.expedia.ca/Zapotlan-El-Grande-Hotels-Hotel-Colon.h48709526.Hotel-Information) Zapotlán el Grande 6.8/10 (165 reviews) "Very nice hotel, nice pool, easy to get to the center and clean" ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Alex CA $36 CA $48 total includes taxes & fees Mar 10 - Mar 11 [](https://www.expedia.ca/Zapotlan-El-Grande-Hotels-Hotel-Colon.h48709526.Hotel-Information) ![Garden](https://images.trvl-media.com/lodging/9000000/8060000/8055700/8055628/a046be8e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/9000000/8060000/8055700/8055628/971c2e17.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; Mexican cuisine ](https://images.trvl-media.com/lodging/9000000/8060000/8055700/8055628/7542c74e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Shower, towels, soap, shampoo](https://images.trvl-media.com/lodging/9000000/8060000/8055700/8055628/3d224f1c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Casa de los Patios Hotel & Spa [](https://www.expedia.ca/Sayula-Hotels-La-Casa-De-Los-Patios-Hotel-Spa.h8055628.Hotel-Information) Sayula 9.4/10 Exceptional (147 reviews) "The hotel is beautiful and staffing is great!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tony [](https://www.expedia.ca/Sayula-Hotels-La-Casa-De-Los-Patios-Hotel-Spa.h8055628.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/10000000/9610000/9600500/9600476/97e893e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/10000000/9610000/9600500/9600476/1ac93655.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Breakfast, lunch, dinner served; international cuisine ](https://images.trvl-media.com/lodging/10000000/9610000/9600500/9600476/30ee37bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Sauna, hot tub, steam room, hot stone massages, facials](https://images.trvl-media.com/lodging/10000000/9610000/9600500/9600476/8ec93765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Gran Casa Sayula Hotel & Spa [](https://www.expedia.ca/Sayula-Hotels-Gran-Casa-Sayula-Hotel-Spa.h9600476.Hotel-Information) Sayula 9.4/10 Exceptional (133 reviews) "Great hotel in Sayula!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Joseph [](https://www.expedia.ca/Sayula-Hotels-Gran-Casa-Sayula-Hotel-Spa.h9600476.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/111000000/110350000/110349800/110349763/248b22b5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Room, 1 King Bed with Sofa bed, Non Smoking](https://images.trvl-media.com/lodging/111000000/110350000/110349800/110349763/89e3b91b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/111000000/110350000/110349800/110349763/eb32d057.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/111000000/110350000/110349800/110349763/2e211699.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Tryp By Wyndham Ciudad Guzman Uttsa [](https://www.expedia.ca/Zapotlan-El-Grande-Hotels-Tryp-By-Wyndham-Ciudad-Guzman-Uttsa.h110349763.Hotel-Information) Zapotlán el Grande 9.6/10 Exceptional (98 reviews) "Great staff! Extremely clean!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Teresa CA $113 CA $137 total includes taxes & fees Mar 22 - Mar 23 [](https://www.expedia.ca/Zapotlan-El-Grande-Hotels-Tryp-By-Wyndham-Ciudad-Guzman-Uttsa.h110349763.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/102000000/101480000/101472500/101472426/a4e14c65.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/102000000/101480000/101472500/101472426/4766a79c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/102000000/101480000/101472500/101472426/cc344917.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/102000000/101480000/101472500/101472426/f4bc1a40.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Zapotlan [](https://www.expedia.ca/Zapotlan-El-Grande-Hotels-Hotel-Zapotlan.h101472426.Hotel-Information) Zapotlán el Grande 8.0/10 Very good (267 reviews) "Yes, staff very professional and helpful during my stay. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fernando CA $38 CA $46 total includes taxes & fees Mar 26 - Mar 27 [](https://www.expedia.ca/Zapotlan-El-Grande-Hotels-Hotel-Zapotlan.h101472426.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/121000000/120390000/120388200/120388195/31c1218a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Single Room, 1 King Bed, Non Smoking, City View | Interior](https://images.trvl-media.com/lodging/121000000/120390000/120388200/120388195/e47d34f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Quadruple Room, Multiple Beds, Non Smoking, City View | Living area](https://images.trvl-media.com/lodging/121000000/120390000/120388200/120388195/71c7d19c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Laptop workspace, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/121000000/120390000/120388200/120388195/f736d8e4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hotel Uttsa Inn Tamazula [](https://www.expedia.ca/Tamazula-De-Gordiano-Hotels-Hotel-Uttsa-Inn-Tamazula.h120388195.Hotel-Information) Tamazula de Gordiano 10/10 Exceptional (1 review) "Room very clean. Friendly stuff" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Maria Del Carmen CA $95 CA $115 total includes taxes & fees Mar 10 - Mar 11 [](https://www.expedia.ca/Tamazula-De-Gordiano-Hotels-Hotel-Uttsa-Inn-Tamazula.h120388195.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-03-23&endDate=2026-03-24®ionId=553248635976270713&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://forever.travel-assets.com/flex/flexmanager/images/2026/02/06/expedia-sale-2026-desktop-us-ca.jpg?impolicy=fcrop&w=1400&h=600&q=mediumHigh) ## The Annual Vacation Sale Members save up to 40% on hotels and homes. Plan this year’s big trip and save. [Book now](https://expedia.ca/deals?rfrr=HTG_SPRING_PROMO_553248635976270713) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Hotels.d553248635976270713.Travel-Guide-Hotels)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FLa-Mesa-Hotels.d553248635976270713.Travel-Guide-Hotels) ## Top La Mesa Hotel Reviews ## Recent Reviews in La Mesa ![Gran Casa Sayula Hotel & Spa](https://images.trvl-media.com/lodging/10000000/9610000/9600500/9600476/97e893e0_y.jpg) ### Gran Casa Sayula Hotel & Spa 10/10 Excellent "Un lugar muy antiguo con una antiguedad de 200 Años luce muy bien, la atencion es muy buena" [](https://expedia.ca/Sayula-Hotels-Gran-Casa-Sayula-Hotel-Spa.h9600476.Hotel-Information) ![Hotel Zapotlan](https://images.trvl-media.com/lodging/102000000/101480000/101472500/101472426/a4e14c65_y.jpg) ### Hotel Zapotlan 10/10 Excellent "Thank you" [](https://expedia.ca/Zapotlan-El-Grande-Hotels-Hotel-Zapotlan.h101472426.Hotel-Information) ![Capital O Colón, Ciudad Guzmán Jalisco](https://images.trvl-media.com/lodging/49000000/48710000/48709600/48709526/a8b0d54c_y.jpg) ### Capital O Colón, Ciudad Guzmán Jalisco 2/10 Terrible "Hotel was not what the pictures show who inspects and how often does it happen it you name we use to book our reservations. We stayed at the hotel one night with no sleep because there is a club across the street music thumping until 4am ridiculous. That’s just one of the many things wrong with the hotel mold in the restrooms shower heads broken, window screens in our closet. We checked out the next day to another hotel away from all the chaos. Front desk was no help asking for a deposit for our TV remote. I have pictures of everything I have discussed above. " [](https://expedia.ca/Zapotlan-El-Grande-Hotels-Hotel-Colon.h48709526.Hotel-Information) ![La Casa de los Patios Hotel & Spa](https://images.trvl-media.com/lodging/9000000/8060000/8055700/8055628/a046be8e_y.jpg) ### La Casa de los Patios Hotel & Spa 10/10 Excellent "Front desk clerk was very helpful. Waiters need improvement. Rooms nice and clean. " [](https://expedia.ca/Sayula-Hotels-La-Casa-De-Los-Patios-Hotel-Spa.h8055628.Hotel-Information) ![Tryp By Wyndham Ciudad Guzman Uttsa](https://images.trvl-media.com/lodging/111000000/110350000/110349800/110349763/248b22b5_y.jpg) ### Tryp By Wyndham Ciudad Guzman Uttsa 10/10 Excellent "very nice place close to town" [](https://expedia.ca/Zapotlan-El-Grande-Hotels-Tryp-By-Wyndham-Ciudad-Guzman-Uttsa.h110349763.Hotel-Information) ![Hotel Uttsa Inn Tamazula](https://images.trvl-media.com/lodging/121000000/120390000/120388200/120388195/31c1218a_y.jpg) ### Hotel Uttsa Inn Tamazula 10/10 Excellent "Room very clean. Friendly stuff" [](https://expedia.ca/Tamazula-De-Gordiano-Hotels-Hotel-Uttsa-Inn-Tamazula.h120388195.Hotel-Information) ![Basalt hut](https://images.trvl-media.com/lodging/121000000/120150000/120147900/120147816/03374078_y.jpg) ### Basalt hut 10/10 Excellent "Magical, wonderful place and family. I did not want to leave. It’s a very special place. Highly recommended! " [](https://expedia.ca/Comala-Hotels-Vrbo-Property.h120147816.Hotel-Information) ![Lofts Independencia Sayula](https://images.trvl-media.com/lodging/115000000/114160000/114153800/114153710/8a731937_y.jpg) ### Lofts Independencia Sayula 2/10 Terrible "Not satisfied charges for parking, pool and needed to ask for fresh towels n toilet paper no AC" [](https://expedia.ca/Sayula-Hotels-Lofts-Independencia-Sayula.h114153710.Hotel-Information) ![Tryp By Wyndham Ciudad Guzman Uttsa](https://images.trvl-media.com/lodging/107000000/106200000/106190600/106190588/949dc80d_y.jpg) ### Tryp By Wyndham Ciudad Guzman Uttsa 8/10 Good "Stayed for two nights during the Fiestas. Super close to the Féria. However a bit far from the center. Staff was very helpful and room comfortable and clean. Good place to stay if you don’t mind taking a cab into town or driving in and you want some quiet." [](https://expedia.ca/Zapotlan-El-Grande-Hotels-Tryp-By-Wyndham-Ciudad-Guzman-Uttsa.h106190588.Hotel-Information) ## More cheap stays in La Mesa ![Hotel Zapotlan](https://images.trvl-media.com/lodging/102000000/101480000/101472500/101472426/a4e14c65_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Hotel Zapotlan Federico del Toro, 61 Zapotlán el Grande JAL CA $38 CA $46 total Mar 26 - Mar 27 includes taxes & fees 8/10 Very Good! (267 reviews) [](https://expedia.ca/Zapotlan-El-Grande-Hotels-Hotel-Zapotlan.h101472426.Hotel-Information) ![Capital O Colón, Ciudad Guzmán Jalisco](https://images.trvl-media.com/lodging/49000000/48710000/48709600/48709526/a8b0d54c_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Capital O Colón, Ciudad Guzmán Jalisco 655 Avenida Cristobal Colon Zapotlán el Grande JAL CA $36 CA $48 total Mar 10 - Mar 11 includes taxes & fees 6.8/10 (165 reviews) [](https://expedia.ca/Zapotlan-El-Grande-Hotels-Hotel-Colon.h48709526.Hotel-Information) ![Lofts Independencia Sayula](https://images.trvl-media.com/lodging/115000000/114160000/114153800/114153710/8a731937_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Lofts Independencia Sayula 62 Independencia Centro Histórico Sayula Jal. CA $47 CA $57 total Mar 10 - Mar 11 includes taxes & fees 5.4/10 (6 reviews) [](https://expedia.ca/Sayula-Hotels-Lofts-Independencia-Sayula.h114153710.Hotel-Information) ![Tryp By Wyndham Ciudad Guzman Uttsa](https://images.trvl-media.com/lodging/107000000/106200000/106190600/106190588/949dc80d_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Tryp By Wyndham Ciudad Guzman Uttsa Av Jose Maria Gonzalez 552 Col Zapotl Y Fracc Cond Zapotlán el Grande JAL [Get rates](https://expedia.ca/Hotel-Search?startDate=23%2F03%2F2026&endDate=24%2F03%2F2026&selected=106190588&PinnedHotelID=106190588&HadPinnedHotel=true®ionId=553248635976270713) 6/10 (2 reviews) [](https://expedia.ca/Zapotlan-El-Grande-Hotels-Tryp-By-Wyndham-Ciudad-Guzman-Uttsa.h106190588.Hotel-Information) ![Cabanas del Volcan](https://images.trvl-media.com/lodging/40000000/39080000/39070700/39070605/ce4b87bb_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Cabanas del Volcan La Yerbabuena km 1 Comala COL [Get rates](https://expedia.ca/Hotel-Search?startDate=23%2F03%2F2026&endDate=24%2F03%2F2026&selected=39070605&PinnedHotelID=39070605&HadPinnedHotel=true®ionId=553248635976270713) [](https://expedia.ca/Colima-Hotels-Cabanas-Del-Volcan.h39070605.Hotel-Information) ![Cabanas la Decidia Sierra Del Tigre](https://images.trvl-media.com/lodging/49000000/48940000/48931000/48930915/dbf91b65_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Cabanas la Decidia Sierra Del Tigre La Sierra Del Tigre Jalisco Atoyac JAL [Get rates](https://expedia.ca/Hotel-Search?startDate=23%2F03%2F2026&endDate=24%2F03%2F2026&selected=48930915&PinnedHotelID=48930915&HadPinnedHotel=true®ionId=553248635976270713) [](https://expedia.ca/Guadalajara-Hotels-Cabanas-La-Decidia-Sierra-Del-Tigre.h48930915.Hotel-Information) ## Frequently asked questions ### What is the best area to stay in La Mesa? > This area is the heart of La Mesa, offering a convenient and pleasant experience. It's very walkable, with many local shops, restaurants, and the main plaza, Plaza Principal, where you can often find local events. The streets are well-maintained, and you'll find a mix of traditional architecture and modern conveniences. > > > For couples, the city centre provides a romantic and engaging setting. You can enjoy strolls to local eateries, visit the Church of San Pedro, and relax in the plaza. The evenings offer a gentle buzz, great for enjoying a drink or a meal together. > > > Families will also find the city centre a practical and enjoyable option. The main plaza often has activities for children, and there are many family-friendly restaurants. ### When is the best time to go to La Mesa? > During these months, the weather is consistently pleasant, with average temperatures ranging from 20°C to 28°C (68°F to 82°F) and very little rainfall. This makes it ideal for enjoying outdoor activities and sightseeing without the interruption of daily downpours. > > > Couples looking for a romantic getaway will appreciate the consistently clear skies and comfortable evenings, superb for al fresco dining or enjoying a sunset stroll. The good weather ensures that all attractions and outdoor experiences are readily available. > > > Families travelling with children will find the dry season particularly convenient. ### Can I cancel my hotel reservation on Expedia? ### How can I save on a La Mesa hotel booking with Expedia? ### How much is the nightly rate at a La Mesa hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [2 Star Hotels in Mazamitla ](https://www.expedia.ca/2Star-Mazamitla-Hotels.s20-0-d6145616.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Chiquilistlan ](https://www.expedia.ca/3Star-Chiquilistlan-Hotels.s30-0-d6266030.Travel-Guide-Filter-Hotels) - [3 Star Hotels in Tamazula de Gordiano ](https://www.expedia.ca/3Star-Tamazula-De-Gordiano-Hotels.s30-0-d6339564.Travel-Guide-Filter-Hotels) - [Apartments in Ajijic ](https://www.expedia.ca/Ajijic-Apartments.d10334-aaApartments.Travel-Guide-Accommodation) - [Condo Rentals in Ajijic ](https://www.expedia.ca/Ajijic-Condos.d10334-aaCondos.Travel-Guide-Accommodation) - 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