Find hotels in La Mesa from CA $75

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

Filter by

Guest rating
Guest rating
Star rating

Our top choices for La Mesa hotels

B&B Lodgings

B&B Lodgings
2.5 star property
24 de Diciembre
8.0 out of 10, Very good, (81 reviews)
"it was super clean"
United States
Michael
The price is CA $66
CA $73 total
includes taxes & fees
Apr 10 - Apr 11
B&B Lodgings

Boutique Apartments Panamá Coco del Mar

Boutique Apartments Panamá Coco del Mar
3.5 star property
San Francisco
7.4 out of 10, Good, (181 reviews)
"Would recommend this stay to anyone I know who is visiting Panama. We loved our room and also the check in process was easy! "
United States
Andrena
The price is CA $69
CA $270 total
includes taxes & fees
Apr 13 - Apr 14
Boutique Apartments Panamá Coco del Mar

Riande Aeropuerto Hotel & Casino

Riande Aeropuerto Hotel & Casino
4.0 star property
Tocumen
8.4 out of 10, Very good, (1,855 reviews)
"Property was good, would stay there again. "
United States
Juan
The price is CA $187
CA $206 total
includes taxes & fees
Apr 14 - Apr 15
Riande Aeropuerto Hotel & Casino

Crowne Plaza Panama Airport by IHG

Crowne Plaza Panama Airport by IHG
4.0 star property
Tocumen
8.6 out of 10, Excellent, (2,504 reviews)
"Very clean and comfortable stay, beautiful lobby and restaurant."
United States
EL Heru
The price is CA $181
CA $209 total
includes taxes & fees
Apr 16 - Apr 17
Crowne Plaza Panama Airport by IHG

Courtyard by Marriott Panama Metromall

Courtyard by Marriott Panama Metromall
4.0 star property
San Antonio
9.0 out of 10, Wonderful, (1,005 reviews)
"Nice hotel will visit again"
United States
Deisha
The price is CA $140
CA $154 total
includes taxes & fees
May 9 - May 10
Courtyard by Marriott Panama Metromall

Living 73 Panamá by Boutique Apartments

Living 73 Panamá by Boutique Apartments
3.0 star property
San Francisco
The price is CA $69
CA $281 total
includes taxes & fees
Apr 13 - Apr 14
Living 73 Panamá by Boutique Apartments

Boutique Apartments Atlapa

Boutique Apartments Atlapa
3.0 star property
San Francisco
7.6 out of 10, Good, (35 reviews)
"The place was clean nice an its comfortable an the view is to kill for amazing ‼️"
United States
Odaine
The price is CA $55
CA $212 total
includes taxes & fees
May 3 - May 4
Boutique Apartments Atlapa

Arcadia Condo Suites

Arcadia Condo Suites
2.5 star property
Costa del Este
9.4 out of 10, Exceptional, (261 reviews)
"All units are very well equipped with everything that travelers will need. Comfortable and well located, easy access and safe neighborhood. "
United States
Jaime
The price is CA $166
CA $247 total
includes taxes & fees
Apr 10 - Apr 11
Arcadia Condo Suites

ORHO HOTEL BOUTIQUE PANAMA Airport

ORHO HOTEL BOUTIQUE PANAMA Airport
2.0 star property
Tocumen
8.8 out of 10, Excellent, (95 reviews)
"Great place to stay with plenty of places nearby for food and drinks"
United States
Thomas
The price is CA $166
CA $216 total
includes taxes & fees
Apr 10 - Apr 11
ORHO HOTEL BOUTIQUE PANAMA Airport

Ramada Plaza by Wyndham Panama Punta Pacifica

Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
San Francisco
9.6 out of 10, Exceptional, (1,164 reviews)
"The staff was excellent and the overall facility was very clean and inviting "
United States
David
The price is CA $146
CA $160 total
includes taxes & fees
May 6 - May 7
Ramada Plaza by Wyndham Panama Punta Pacifica

Aloft Panama

Aloft Panama
3.5 star property
San Francisco
8.6 out of 10, Excellent, (1,005 reviews)
"The property was amazing, staff was great,very clean, everyone was welcoming, food was good, need more variety for breakfast though"
United States
Ryan
The price is CA $155
CA $171 total
includes taxes & fees
Apr 26 - Apr 27
Aloft Panama

Sheraton Grand Panama

Sheraton Grand Panama
4.0 star property
San Francisco
8.6 out of 10, Excellent, (1,001 reviews)
"Breakfast was great , clean room and staff was nice "
United States
Pauline
The price is CA $175
CA $193 total
includes taxes & fees
May 1 - May 2
Sheraton Grand Panama

w Bright 1BR w Private Balcony in San Francisco

w Bright 1BR w Private Balcony in San Francisco
2.0 star property
San Francisco
The price is CA $161
CA $217 total
includes taxes & fees
Apr 12 - Apr 13
w Bright 1BR w Private Balcony in San Francisco

Swette Love 10 Minutes From the Airport Tocumen

Swette Love 10 Minutes From the Airport Tocumen
2.0 star property
Las Mañanitas
The price is CA $81
CA $105 total
includes taxes & fees
Apr 16 - Apr 17
Swette Love 10 Minutes From the Airport Tocumen

The Westin Panama

The Westin Panama
4.0 star property
Costa del Este
9.0 out of 10, Wonderful, (327 reviews)
"Clean room, helpful staff, good breakfast."
United States
Stephanie
The price is CA $297
CA $326 total
includes taxes & fees
May 2 - May 3
The Westin Panama

Dovle Residences by HMS-Preferred Member

Dovle Residences by HMS-Preferred Member
2.5 star property
San Francisco
6.6 out of 10, (7 reviews)
"Inadequate heating in the pool , poor customer service. No hot water in the shower. It was a terrible experience but it’s a nice place, hopefully with better management can offer outstanding services "
United States
Herbert
The price is CA $178
CA $195 total
includes taxes & fees
Apr 12 - Apr 13
Dovle Residences by HMS-Preferred Member

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
5.0 star property
Juan Diaz
9.6 out of 10, Exceptional, (685 reviews)
"As usual the stay was amazing in this hotel"
United States
Jose
The price is CA $373
CA $410 total
includes taxes & fees
May 2 - May 3
The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City

Express Inn Panama International Airport Hostel

Express Inn Panama International Airport Hostel
1.5 star property
Tocumen
6.0 out of 10, (685 reviews)
"It was clean and did the job"
United States
Gabriel
The price is CA $69
CA $75 total
includes taxes & fees
Apr 10 - Apr 11
Express Inn Panama International Airport Hostel

Charming 3 Bedroom Apartment in San Miguelito, Panama City

Charming 3 Bedroom Apartment in San Miguelito, Panama City
2.0 star property
José Domingo Espinar
2.0 out of 10, (1 review)
"La habitacion terrible, edificio sucio ubicacion pesima "
Mexico
caleb
The price is CA $97
CA $107 total
includes taxes & fees
Apr 11 - Apr 12
Charming 3 Bedroom Apartment in San Miguelito, Panama City
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in

Top La Mesa Hotel Reviews

Recent Reviews in La Mesa

More cheap stays in La Mesa

Frequently asked questions

Where is the best place to stay in La Mesa?
Sheraton Grand Panama, located 19.4 mi (31.3 km) from the heart of La Mesa, is a top choice for your stay based on our traveler data. Other good options for your stay in the area are Crowne Plaza Panama Airport by IHG and Ramada Plaza by Wyndham Panama Punta Pacifica. See all available top hotels, or vacation rentals in La Mesa.
What are some of the best vacation home rentals in La Mesa?
Cozy 3-bedroom townhome with WiFi, AC in fabulous Panamá: Visitors like this La Mesa vacation home rental. It is equipped with a selection of books, air-conditioning, and laundry facilities to help you feel comfortable during your stay. It has 3 bedrooms as well as a kitchen with a fridge, an oven, and a microwave, so you can cook with friends or family. See all vacation rentals in La Mesa.
If I need to cancel my hotel reservation in La Mesa, will I receive a refund?
Yes, the majority of room reservations are fully refundable as long as you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before check in. If you booked a non-refundable reservation, you may still be able to cancel and get a refund within a 24-hour period of booking. Filter your search by fully refundable to find flexible hotel deals in La Mesa.
What is staying in La Mesa like?
Visitors to La Mesa are sure to find plenty to explore and enjoy. There are 370 hotels and other accommodations in the surrounding area. Find out more about La Mesa.
What are the top places to visit in La Mesa?
Places to visit in the wider area include Metromall Panama, Los Pueblos Commercial Center, and Estadio Rommel Fernandez. You'll also find Chagres National Park and Chepo Youth Recreation Center in the area. Check out what more to see and do in Expedia's La Mesa guide.
What's the weather like in La Mesa?
The hottest months are usually April and March with an average temp of 80°F, while the coldest months are January and February with an average of 79°F. The rainiest months in La Mesa are July, August, October, and June, with each month seeing an average of 14 inches of rainfall.

Explore a world of travel with Expedia