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A historic cathedral with two domes and bell towers, surrounded by a plaza.

Guadalupe Vacation Rentals

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    Check prices for these dates, December 14–15, 2026

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    Our top choices for Guadalupe vacation rentals

    1. HIDALGO 119 - TERRAZA Y SUITES

    A corridor with a wooden floor, potted plants, and a door marked "SALIDA DE EMERGENCIA".

    Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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    Top Guadalupe Hotel Reviews

    Hampton Inn by Hilton Zacatecas

    A lobby with a beige sofa, two patterned armchairs, a central coffee table, and a large abstract painting on the wall.

    Santa Rita Hotel del Arte

    A rooftop terrace with string lights, a table set for dining, and a view of a historic church with two towers.

    Hotel Don Miguel

    A swimming pool with a glass ceiling, a sign reading 'DON MIGUEL,' and a view of the sky.

    Matiana

    A lobby with a reception desk, a staircase, and three chandeliers.

    Hotel La Finca del Minero

    A yellow building with a balcony, a door, and a window.

    Hotel Mesón de Jobito

    A grand entrance with a chandelier, arched doorways, and a staircase leading to a courtyard.

    Hotel Mesón de la Merced

    A historic building with a hotel named 'HOTEL MESON DE LA MERCED' under an archway, a white van parked in front, and a cobblestone street reflecting lights.

    Hotel Casa Santa Lucia

    A terrace with a round table and chairs, a potted plant, and a view of a historic building with a dome and bell tower.

    Hotel María Benita

    A courtyard with a stone wall, a metal railing, and a tiled floor.

    Find out more about Guadalupe

    Everything you need to know about Guadalupe vacation rentals

    Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Guadalupe vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

    There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Guadalupe vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

    Guadalupe vacation rentals: An excellent choice for every season

    Whenever you want to travel, a warm welcome awaits you in Guadalupe. If you’re looking for a little peace, consider booking during the quieter months, such as . For more hustle and bustle, you may prefer to visit in .

    Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Guadalupe vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in. The selection of Guadalupe vacation rentals we have selected for you start as low as CA $32 per night. Entering your travel dates in the search wizard you might find even better deals!

    How to find incredible deals on Guadalupe rentals

    At Expedia, we put the best Guadalupe vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

    To find some top Guadalupe rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Guadalupe vacation.

    If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Guadalupe. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

    Frequently Asked Questions

    Can I find a vacation rental in Guadalupe?

    Yes, you can find vacation rentals close to top points of interest in Guadalupe, or you can go with a secluded option if you're looking for relaxation.

    What are some of the best vacation rentals in Guadalupe?

    Casa Ramona/ Garden/ Relax/ Pet Friendly: Visitors give good reviews to this Guadalupe vacation home rental, which has laundry facilities and WiFi to help you feel perfectly comfortable in your new surroundings.

    What can I see and do in Guadalupe?

    While you're exploring the area, Bufa Hill and El Eden Mine are a couple of picturesque spots to get outside and enjoy nature. Bibayoff Vinos and Rafael Coronel Museum are a couple of places you'll find in the larger area.

    What are vacation rentals like in Guadalupe?

    Vacation rentals are private properties you can reserve for a couple days or more in Guadalupe. Vacation rentals provide amenities like kitchens and laundry facilities so you'll feel just like you're at home. If you're concerned about a clean environment, vacation rentals can provide a sense of seclusion away from public hotel elevators and busy reception areas while still allowing you to travel. You'll also get more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive option for a small group gathering.

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