A cityscape with a prominent modern building, a waterfall, and surrounding greenery.

Find Spa Hotels in Greenville, NC from CA $107

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Check availability on Greenville Spa Hotels

Tonight
Sep 13 - Sep 14
Tomorrow
Sep 14 - Sep 15
Next weekend
Sep 18 - Sep 20
In two weeks
Sep 25 - Sep 27
No exact matches found, but these alternatives could be just right

Recommended hotels in Greenville

A circular fire pit with seating around it, a covered patio area, and a brick building in the background.
A hotel room with two beds, a desk, a chair, a TV, and a window with curtains.
A modern kitchen with wooden cabinets, a central island with plates, a coffee machine, and waffle makers.
A multi-story hotel with a modern design, featuring a prominent entrance with a covered area and a sign reading "HOMEWOOD SUITES by Hilton".

1. Homewood Suites By Hilton Greenville, NC

Homewood Suites By Hilton Greenville, NC
Greenville
CA $147
CA $166 total
includes taxes & fees
Oct 4 - Oct 5
Homewood Suites By Hilton Greenville, NC
A conference room with a wooden table, four chairs, a potted plant, and a decorative wall panel.
A Holiday Inn hotel entrance at night with a full moon in the sky.
A modern bar area with a long counter, multiple stools, and a seating area with sofas and chairs.
A hotel room with a bed, desk, chair, kitchenette, and TV.

2. Holiday Inn Greenville by IHG

Holiday Inn Greenville by IHG
Convention District
CA $133
CA $150 total
includes taxes & fees
Sep 21 - Sep 22
Holiday Inn Greenville by IHG
A modern hotel with a stone facade, large windows, and a well-lit entrance.
A modern hotel lobby with a sofa, armchairs, a coffee table, and a reception desk.
A rooftop terrace with outdoor furniture, a pergola with string lights, and a view of the cityscape.
A modern interior with a sign reading "The Rooftop".

3. Hilton Garden INN Greenville University

Hilton Garden INN Greenville University
Uptown Greenville
CA $169
CA $192 total
includes taxes & fees
Sep 20 - Sep 21
Hilton Garden INN Greenville University
A modern hotel room with a large bed, a desk with a chair, a flat-screen TV mounted on the wall, and a wardrobe.
A modern reception area with a wooden reception desk, blue seating, and a large window providing natural light.
A modern bathroom with a large mirror, a glass shower enclosure, and a white countertop.

4. Holiday Inn Express Greenville by IHG

Holiday Inn Express Greenville by IHG
Greenville
CA $164
CA $185 total
includes taxes & fees
Oct 4 - Oct 5
Holiday Inn Express Greenville by IHG
A hotel room with a desk, two beds, a sofa, a TV, and a coffee machine.
A restaurant with a counter, seating area, and various food items displayed.
A hotel room with a bed, a grey sofa, a dark armchair, a wooden coffee table, and a patterned carpet.
A hotel room with a dining area, a TV, a desk, a chair, a sofa, a large mirror, a lamp, and a bathtub.

5. Best Western Plus Suites-Greenville

Best Western Plus Suites-Greenville
Greenville
CA $166
CA $188 total
includes taxes & fees
Sep 20 - Sep 21
Best Western Plus Suites-Greenville
An outdoor patio with seating, potted plants, and a brick fireplace.
A hotel room with two beds, a desk, a TV, and a window with a city view.
A hotel lobby with a long reception desk, multiple seating areas, and a modern chandelier.
An indoor swimming pool with clear windows, a lifeguard sign, and a pool depth marker.

6. Hampton Inn Greenville

Hampton Inn Greenville
Convention District
CA $174
CA $196 total
includes taxes & fees
Oct 4 - Oct 5
Hampton Inn Greenville
A Courtyard by Marriott hotel with a covered entrance, outdoor seating, and a landscaped area.
A breakfast bar with various food items, a coffee machine, and a menu board.
A circular outdoor seating area with a fire pit, surrounded by chairs and tables, set against a backdrop of neatly trimmed hedges and a large tree.
A modern office with a desk, computer, and ergonomic chair. There is a television on the wall and a window with a view of greenery.

7. Courtyard Marriott Greenville

Courtyard Marriott Greenville
Medical District
CA $176
CA $199 total
includes taxes & fees
Sep 17 - Sep 18
Courtyard Marriott Greenville
A spacious lobby with a blue sofa, yellow armchairs, a central coffee table, and a wooden balcony railing.
A Comfort Inn & Suites hotel entrance with a modern facade, large glass doors, and a clear sky.
A lobby with a modern design, featuring a seating area with sofas and armchairs, a coffee table, and artwork on the walls.
A modern bathroom with a large mirror, a wooden vanity, a bathtub, and a shower area.

8. Comfort Inn & Suites Greenville Near East Carolina University

Comfort Inn & Suites Greenville Near East Carolina University
Greenville
CA $152
CA $172 total
includes taxes & fees
Oct 4 - Oct 5
Comfort Inn & Suites Greenville Near East Carolina University
A multi-story hotel with a covered entrance, large windows, and a brick facade.
A hotel room with a large bed, a sofa, a television, and a mirror.
A dining area with wooden tables and chairs, a kitchen counter with appliances, and framed pictures on the wall.
A conference room with a long table, leather chairs, and a chandelier.

9. Microtel Inn & Suites by Wyndham Greenville/University Medic

Microtel Inn & Suites by Wyndham Greenville/University Medic
Greenville
CA $94
CA $107 total
includes taxes & fees
Oct 4 - Oct 5
Microtel Inn & Suites by Wyndham Greenville/University Medic
A spacious lobby with a stone fireplace, comfortable seating, and a bar area.
A spacious lobby with a modern design, featuring a large seating area, a reception desk, and a television screen.
A modern kitchen with a large island, bar stools, and a TV displaying a football game.
A modern kitchen with wooden cabinets, a stainless steel refrigerator, a microwave, and a coffee maker.

10. Staybridge Suites Greenville Medical Center by IHG

Staybridge Suites Greenville Medical Center by IHG
Greenville
CA $176
CA $199 total
includes taxes & fees
Sep 20 - Sep 21
Staybridge Suites Greenville Medical Center by IHG
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Choose what matters most at spa hotels in Greenville

Pool
Breakfast included
Hot tub
4 stars
5 stars

Find out more about Greenville

Top Greenville attractions for a relaxing vacation

Greenville, North Carolina, offers an appealing blend of relaxation and adventure for travellers seeking spa hotels. Begin your journey at the serene River Park North, where you can stroll along scenic paths or kayak in tranquil waters, perfect for unwinding before or after a spa day. Next, immerse yourself in the vibrant local arts scene at the Greenville Museum of Art, showcasing impressive Southern artworks, followed by a leisurely afternoon at the nearby Uptown Greenville, known for its eclectic shops and inviting cafés. For those who enjoy outdoor activities, the nearby East Carolina University campus boasts beautiful gardens and walking trails that are ideal for a refreshing escape. Finally, the popular Greenville Town Common provides a picturesque setting for picnics and outdoor concerts, all while being a stone's throw from hotels that offer spa services. Staying in the heart of the city allows you to enjoy both comfort and convenience, with attentive service and pampering experiences readily available at your fingertips.

Find the best hotels & resorts with spas in Greenville

For travelers seeking relaxation and rejuvenation in Greenville, North Carolina, these hotels provide a perfect retreat with spa amenities to soothe the senses.Microtel Inn & Suites by Wyndham Greenville/University Medic

  • Why it's great for tailored spa getaway: The Microtel Inn & Suites by Wyndham Greenville/University Medic is an ideal choice for guests looking to unwind with spa services, featuring in-room massage options for a tranquil experience. With a solid guest review rating of 7.2, this hotel offers a comfortable and inviting atmosphere to relax after a long day of exploring or business meetings.
  • Other amenities: Guests can enjoy complimentary breakfast daily, including continental options on weekends, ensuring a delightful start to the day. The hotel also provides 24-hour fitness facilities, free self-parking, and early check-in/late check-out options to accommodate various schedules. With daily housekeeping and free toiletries, guests will find convenience and comfort throughout their stay.
  • Nearby attractions: Guy Smith Stadium - 0.5 km

Top Greenville Hotel Reviews

Hampton Inn Greenville

Hampton Inn Greenville

10/10 Excellent
"Breakfast was great"
Rose 2-night trip
Posted 2 days ago
Hampton Inn Greenville
Microtel Inn & Suites by Wyndham Greenville/University Medic

Microtel Inn & Suites by Wyndham Greenville/University Medic

8/10 Good
"Location is very convenient to the hospital for early surgeries. Only a couple minutes away."
Amy 1-night trip
Posted 5 days ago
Microtel Inn & Suites by Wyndham Greenville/University Medic

Frequently asked questions

How much does a spa hotel in Greenville cost?
Enjoy staying in a spa hotel in Greenville, with plenty of hotels from CA $107 offering incredible amenities. If you're leaning toward a little luxury, prices can rise, and may vary depending on the location, season, and hotel amenities. Be sure to book in advance to enjoy more options and potentially better rates, especially if you're planning a trip during the weekend or around public holidays.
Is it cheaper to book a spa hotel in Greenville with flights as part of a package deal?
Booking a hotel and flight package on Expedia can be cheaper than booking flights and hotels separately. Bundling can lead to significant savings, especially for international travel or when booking well in advance. However, savings vary depending on factors like destination, travel dates, and availability, so it's wise to compare options. With access to over 300,000 hotels worldwide, Expedia makes it easy to build the perfect travel package.
Are there any unique spa experiences available in Greenville?
Yes, Greenville, North Carolina offers several unique spa experiences that stand out for their specialised treatments and distinctive approaches.Poseidon Spa at Grand Bohemian Lodge Greenville offers water-inspired treatments, with quiet, refreshing treatment rooms and group spa experiences emphasising the healing power of water as a wellness ritual.Solace Flow Head Spa provides a luxurious head spa experience based on Japanese and Ayurvedic traditions, focusing on holistic scalp care using exclusive Italian products and specialised services such as Scalp Revive, Balance Harmony, and Roots Renewal to stimulate hair growth and scalp health.Drift Float & Spa offers a unique floating experience in Epsom salt, combined with infrared therapy, contrast therapy (heat and cold), and meditative light experiences, all aimed at deep relaxation, muscle recovery, detoxification, and mental wellness through innovative therapies.
Can I cancel my spa hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline. This is often within 24-48 hours of your scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use Expedia's "Fully refundable property" filter during your search to find the right spa hotel in Greenville for you.
How can I save on a spa hotel in Greenville with Expedia?
Find Greenville spa hotel deals by joining One Key™, Expedia's free travel rewards program. As a member, you can unlock instant savings with Member Prices when you're logged in. For a quick weekend retreat, discover last-minute offers.

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