Title: Book the Best BUSINESS Hotels in Durham in 2026 | Expedia.ca [Hotels in Durham](https://expedia.ca/Durham-Hotels.d7940.Travel-Guide-Hotels)[Vacation Rentals in Durham](https://expedia.ca/Durham-Vacation-Rentals.d7940.Travel-Guide-VacationRentals)[Flights to Durham](https://expedia.ca/Cheap-Flights-To-Durham.d7940.Travel-Guide-Flights)[Things to do in Durham](https://expedia.ca/Things-To-Do-In-Durham.d7940.Travel-Guide-Activities)[Durham Car Rentals](https://expedia.ca/Car-Rentals-In-Durham.d7940.Car-Rental-Guide)[Durham Vacation Packages](https://expedia.ca/Durham.d7940.Destination-Travel-Guides) ![College town in winter -Durham, New Hampshire ](https://images.trvl-media.com/place/7940/8b9c201d-fa97-4e76-888c-590d01f2d194.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/7940/8b9c201d-fa97-4e76-888c-590d01f2d194.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Durham Business Hotels Tonight [Jan 15 - Jan 16](https://www.expedia.ca/Hotel-Search?regionId=7940&startDate=2026-01-15&endDate=2026-01-16&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Jan 16 - Jan 17](https://www.expedia.ca/Hotel-Search?regionId=7940&startDate=2026-01-16&endDate=2026-01-17&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Jan 16 - Jan 18](https://www.expedia.ca/Hotel-Search?regionId=7940&startDate=2026-01-16&endDate=2026-01-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Jan 23 - Jan 25](https://www.expedia.ca/Hotel-Search?regionId=7940&startDate=2026-01-23&endDate=2026-01-25&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Durham business-friendly hotels ![Exterior](https://images.trvl-media.com/lodging/2000000/1510000/1507300/1507215/941e3cbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1510000/1507300/1507215/e5c87367.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, soundproofing, iron/ironing board](https://images.trvl-media.com/lodging/2000000/1510000/1507300/1507215/cfc1b5b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1510000/1507300/1507215/658bdde4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Durham by IHG [](https://www.expedia.ca/Portsmouth-Hotels-Holiday-Inn-Express-Durham.h1507215.Hotel-Information) Durham 8.6/10 Excellent (901 reviews) "Nice clean food & dining area. Wide variety of breakfast choices" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kathleen CA $169 CA $184 total includes taxes & fees Feb 15 - Feb 16 [](https://www.expedia.ca/Portsmouth-Hotels-Holiday-Inn-Express-Durham.h1507215.Hotel-Information) ![Premium bedding, in-room safe, desk, laptop workspace](https://images.trvl-media.com/lodging/4000000/3820000/3814100/3814061/w3837h2557x3y3-10e2ec91.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Executive Suite, 1 King Bed | Living area](https://images.trvl-media.com/lodging/4000000/3820000/3814100/3814061/w3837h2556x3y4-e8cf95f5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/4000000/3820000/3814100/3814061/9f9ed9d5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/4000000/3820000/3814100/3814061/fe8eb163.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn & Suites Exeter [](https://www.expedia.ca/Portsmouth-Hotels-Hampton-Inn-Suites-Exeter.h3814061.Hotel-Information) Exeter 9.2/10 Wonderful (1,001 reviews) "Friendly service, quiet area and clean room. Will stay here again." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) William CA $131 CA $142 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Portsmouth-Hotels-Hampton-Inn-Suites-Exeter.h3814061.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/520000/517500/517424/e05bdc89.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/520000/517500/517424/4f7aa680.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/520000/517500/517424/defc498d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/1000000/520000/517500/517424/8fe7356c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Howard Johnson by Wyndham Portsmouth [](https://www.expedia.ca/Portsmouth-Hotels-Howard-Johnson-By-Wyndham-Portsmouth.h517424.Hotel-Information) Portsmouth 8.6/10 Excellent (1,000 reviews) "Quiet hotel, friendly staff. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristalee CA $101 CA $110 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Portsmouth-Hotels-Howard-Johnson-By-Wyndham-Portsmouth.h517424.Hotel-Information) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/2000000/1100000/1094500/1094420/579e0ae6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/2000000/1100000/1094500/1094420/5c0302c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior detail](https://images.trvl-media.com/lodging/2000000/1100000/1094500/1094420/1d56b8ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1100000/1094500/1094420/f443f84e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Coachman Inn [](https://www.expedia.ca/Kittery-Hotels-Coachman-Inn.h1094420.Hotel-Information) Kittery 7.8/10 Good (1,001 reviews) "Great place to stay." ![Canada](https://a.travel-assets.com/egds/marks/flags/ca.svg) Linda CA $82 CA $94 total includes taxes & fees Jan 18 - Jan 19 [](https://www.expedia.ca/Kittery-Hotels-Coachman-Inn.h1094420.Hotel-Information) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/59000000/58810000/58809600/58809537/c07bf05d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/59000000/58810000/58809600/58809537/68ff38d0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/59000000/58810000/58809600/58809537/c7a90e52.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/59000000/58810000/58809600/58809537/65ced5c3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express Wells-Ogunquit-Kennebunk by IHG [](https://www.expedia.ca/Wells-Hotels-Holiday-Inn-Express-Wells-Ogunquit-Kennebunk.h58809537.Hotel-Information) Wells 9.2/10 Wonderful (584 reviews) "Staff was friendly. Room was spacious, clean and quiet " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Deborah CA $114 CA $124 total includes taxes & fees Feb 2 - Feb 3 [](https://www.expedia.ca/Wells-Hotels-Holiday-Inn-Express-Wells-Ogunquit-Kennebunk.h58809537.Hotel-Information) ![Indoor spa tub](https://images.trvl-media.com/lodging/2000000/1390000/1385400/1385319/f668ac0f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/2000000/1390000/1385400/1385319/7c3975cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor spa tub](https://images.trvl-media.com/lodging/2000000/1390000/1385400/1385319/50bc7b1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/2000000/1390000/1385400/1385319/dbf3df9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Meadowmere Resort [](https://www.expedia.ca/Ogunquit-Hotels-Meadowmere-Resort.h1385319.Hotel-Information) Ogunquit 8.6/10 Excellent (1,000 reviews) "We loved our stay- 10/10 would go back again!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) George CA $193 CA $256 total includes taxes & fees Jan 17 - Jan 18 [](https://www.expedia.ca/Ogunquit-Hotels-Meadowmere-Resort.h1385319.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/119000000/118250000/118243000/118242928/w3840h2556x0y3-bb4935fe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/119000000/118250000/118243000/118242928/w3836h2558x4y4-d61330d4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/119000000/118250000/118243000/118242928/w3836h2557x4y4-088bec4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, laptop workspace, blackout drapes, soundproofing](https://images.trvl-media.com/lodging/119000000/118250000/118243000/118242928/fa2ba286.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Home2 Suites By Hilton Kittery [](https://www.expedia.ca/Kittery-Hotels-Home2-Suites-By-Hilton-Kittery.h118242928.Hotel-Information) Kittery 9.4/10 Exceptional (53 reviews) "Staff was wonderful!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nancy CA $153 CA $166 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Kittery-Hotels-Home2-Suites-By-Hilton-Kittery.h118242928.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/18000000/17930000/17924500/17924431/4b84503a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17930000/17924500/17924431/8ae9783e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17930000/17924500/17924431/eef7beed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/18000000/17930000/17924500/17924431/429c2f1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Garrison Hotel & Suites Dover-Portsmouth, an Ascend Collection Hotel [](https://www.expedia.ca/Portsmouth-Hotels-The-Garrison-Hotel-Suites-Dover-Durham.h17924431.Hotel-Information) Dover 9.2/10 Wonderful (1,002 reviews) "Staff was very kind and accommodating. Breakfast was delicious with a wide variety. Our room was clean and beds were very comfortable. Highly recommend. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Randi CA $124 CA $134 total includes taxes & fees Jan 22 - Jan 23 [](https://www.expedia.ca/Portsmouth-Hotels-The-Garrison-Hotel-Suites-Dover-Durham.h17924431.Hotel-Information) ![Lunch, dinner, brunch served; seafood, garden views ](https://images.trvl-media.com/lodging/1000000/20000/18100/18086/058ff708.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/20000/18100/18086/d8f5904a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/1000000/20000/18100/18086/6d4bb5ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 Queen Bed](https://images.trvl-media.com/lodging/1000000/20000/18100/18086/3a54396d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lamie's Inn and The Old Salt Restaurant [](https://www.expedia.ca/Portsmouth-Hotels-Lamies-Inn-And-The-Old-Salt-Restaurant.h18086.Hotel-Information) Hampton 9.4/10 Exceptional (1,000 reviews) "Wonderful place, with friendly and responsive staff, beautiful and comfortable rooms in a great location." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Frederick CA $129 CA $140 total includes taxes & fees Jan 20 - Jan 21 [](https://www.expedia.ca/Portsmouth-Hotels-Lamies-Inn-And-The-Old-Salt-Restaurant.h18086.Hotel-Information) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/33000000/32490000/32489400/32489324/7b47e3e0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/33000000/32490000/32489400/32489324/27dedb84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, free WiFi, bed sheets](https://images.trvl-media.com/lodging/33000000/32490000/32489400/32489324/46cc40b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/33000000/32490000/32489400/32489324/d155c752.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### SpringHill Suites by Marriott Hampton Portsmouth [](https://www.expedia.ca/Portsmouth-Hotels-SpringHill-Suites-By-Marriott-Hampton-Portsmouth.h32489324.Hotel-Information) Hampton 9.4/10 Exceptional (849 reviews) "Everything was fantastic from check in until check out. It is one of our favorite places to stay when we visit this area!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Shelley M CA $142 CA $154 total includes taxes & fees Jan 20 - Jan 21 [](https://www.expedia.ca/Portsmouth-Hotels-SpringHill-Suites-By-Marriott-Hampton-Portsmouth.h32489324.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-30&endDate=2026-01-31®ionId=7940&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Durham Hotel Reviews ![Anchorage Inn and Resort](https://images.trvl-media.com/lodging/10000000/9320000/9317700/9317652/68fa4886_y.jpg) ### Anchorage Inn and Resort 10/10 Excellent "The room was very clean. Staff was friendly." [](https://expedia.ca/York-Hotels-Anchorage-Inn-And-Resort.h9317652.Hotel-Information) ![Cliff House Maine](https://images.trvl-media.com/lodging/4000000/3990000/3981200/3981160/eb122fc0_y.jpg) ### Cliff House Maine 10/10 Excellent "Loved the hotel had a great time with a group of friends " [](https://expedia.ca/Cape-Neddick-Hotels-Cliff-House-Maine.h3981160.Hotel-Information) ![Lamie's Inn and The Old Salt Restaurant](https://images.trvl-media.com/lodging/1000000/20000/18100/18086/3a54396d_y.jpg) ### Lamie's Inn and The Old Salt Restaurant 10/10 Excellent "😁" [](https://expedia.ca/Portsmouth-Hotels-Lamies-Inn-And-The-Old-Salt-Restaurant.h18086.Hotel-Information) ![Meadowmere Resort](https://images.trvl-media.com/lodging/2000000/1390000/1385400/1385319/c1d22544_y.jpg) ### Meadowmere Resort 10/10 Excellent "Beautifully clean very spacious room. Lovely jacuzzi spa for 2\. Cozy warm fireplace and big comfy king size bed. Victorian furniture. Delightful stay." [](https://expedia.ca/Ogunquit-Hotels-Meadowmere-Resort.h1385319.Hotel-Information) ![Fairfield Inn by Marriott Portsmouth-Seacoast](https://images.trvl-media.com/lodging/1000000/10000/6800/6779/017aeeb0_y.jpg) ### Fairfield Inn by Marriott Portsmouth-Seacoast 10/10 Excellent "Yes" [](https://expedia.ca/Portsmouth-Hotels-Fairfield-Inn-By-Marriott-Portsmouth-Seacoast.h6779.Hotel-Information) ![Best Western Hampshire Inn](https://images.trvl-media.com/lodging/3000000/2480000/2475600/2475562/ec99ca0c_y.jpg) ### Best Western Hampshire Inn 10/10 Excellent "sure" [](https://expedia.ca/Portsmouth-Hotels-Best-Western-Hampshire-Inn.h2475562.Hotel-Information) ![Hampton Inn Portsmouth Central](https://images.trvl-media.com/lodging/1000000/60000/55600/55572/e343f353_y.jpg) ### Hampton Inn Portsmouth Central 10/10 Excellent "Staff was courteous, breakfast was hot and good, bed was comfortable, and it was nice sitting with a book by the fireplace in the small lobby..an unexpected homey touch" [](https://expedia.ca/Portsmouth-Hotels-Hampton-Inn-Portsmouth-Central.h55572.Hotel-Information) ![Residence Inn by Marriott Portsmouth Downtown/ Waterfront](https://images.trvl-media.com/lodging/4000000/3510000/3500300/3500249/57248fdc_y.jpg) ### Residence Inn by Marriott Portsmouth Downtown/ Waterfront 10/10 Excellent "The breakfast had all kinds of goodies. Oatmeal, with several toppings to choose from. The hot menu seems to change from day to day. We were there for a week, had eggs & bacon one day, then sausage patties and links the next. They surprised me on day 4 by having spinach quiche! Cereals, juice, breads, ect. also available. Coffee, tea, & hot cocoa 24/7\. Our suite had everything we needed. Kitchen had everything we needed to cook and eat. Bathroom has FULL SIZE shampoo, conditioner, and body wash! Heated indoor pool! Oh, and what really made us book here: Dog friendly!! I really have no complaints about our stay BUT the parking situation. $45/day valet, meters, or parking garage? Booo! But I'll still stay here again!" [](https://expedia.ca/Portsmouth-Hotels-Residence-Inn-By-Marriott-Portsmouth-Downtown-Waterfront.h3500249.Hotel-Information) ![Hilton Garden Inn Portsmouth Downtown](https://images.trvl-media.com/lodging/2000000/1470000/1464400/1464340/7de77d01_y.jpg) ### Hilton Garden Inn Portsmouth Downtown 10/10 Excellent "The room was really clean. The only negative are the chairs in the rooms are hard as a rock and not comfortable. " [](https://expedia.ca/Portsmouth-Hotels-Hilton-Garden-Inn-Portsmouth-Downtown.h1464340.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Durham cost? ### What are the best business-friendly hotels in Durham? ### How many business-friendly hotels are there in Durham? ### What are the best cheap business-friendly hotels in Durham? ### Are there any family-friendly hotels in Durham that are also business friendly? ### Why book your business-friendly hotel in Durham with Expedia? ### How can I find cheap business-friendly hotels in Durham? ### What is there to do in Durham near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [Beach Hotel Hotels in Barrington ](https://www.expedia.ca/Barrington-Hotels-Beach-Hotel.0-0-d6333108-tBeachHotel.Travel-Guide-Filter-Hotels) - [Boutique Hotels in Barrington ](https://www.expedia.ca/Barrington-Hotels-Boutique-Hotel.0-0-d6333108-tBoutiqueHotel.Travel-Guide-Filter-Hotels) - 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