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Our top choices for Duke Regional Hospital hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.
A narrow hallway with shelves stocked with snacks and beverages, leading to a room with a desk and chair.
A large indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls, with large windows allowing natural light.
A Hampton Inn hotel with a modern facade, multiple floors, and a parking lot.

1. Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85
2.2 km from Duke Regional Hospital
United States
Cindy
CA $168
CA $191 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn & Suites Durham/North I-85
A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.
A gym with various exercise machines, a large mirror, and a television on the wall.
A Holiday Inn Express hotel with a modern design, featuring a prominent sign, multiple windows, and a well-lit entrance.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.

2. Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG
2.4 km from Duke Regional Hospital
United States
Kimberly R
CA $165
CA $188 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express Durham by IHG
A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.
A hotel room with a bed, bedside tables, a nightstand, a mirror, and a bathroom with a sink and mirror.
A Red Roof Inn with a modern architectural design, featuring a prominent red sign and a well-maintained lawn.
A spacious hallway with wooden flooring, white walls, and multiple windows with blinds. There are two white chairs and a small table with a basket.

3. Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center
2.3 km from Duke Regional Hospital
United States
Luis
CA $89
CA $104 total
includes taxes & fees
Oct 11 - Oct 12
Red Roof Inn Durham - Duke Univ Medical Center
A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.
An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.
A modern hotel lobby with a reception desk, seating area, and a cityscape mural on the wall.
A modern dining area with a long table, multiple chairs, and a sofa with red ottomans.

4. Hampton Inn & Suites Durham University Medical Center

Hampton Inn & Suites Durham University Medical Center
5 km from Duke Regional Hospital
United States
Nicole
CA $178
CA $202 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn & Suites Durham University Medical Center
An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.
A modern restaurant with round tables and yellow chairs, a bar area, and a 'Hello Fall' sign.
A multi-story hotel with a brick facade, large windows, and a well-lit entrance.
A modern living room with a fireplace, two sofas, a coffee table, and a TV mounted on the wall.

5. Fairfield by Marriott Inn & Suites Durham

Fairfield by Marriott Inn & Suites Durham
18.2 km from Duke Regional Hospital
United States
Yolanda
CA $164
CA $186 total
includes taxes & fees
Oct 29 - Oct 30
Fairfield by Marriott Inn & Suites Durham
A bar area with wooden bar stools, pendant lighting, and a counter with a glass display. There are tables and chairs in the background, and the room has a wooden floor.
A covered porch with steps leading to a door, a brick wall, and a street lamp.
A hotel room with two beds, a sofa, a TV, and a bathroom visible through a door.
A colonial-style building with a covered porch, multiple windows, and outdoor seating.

6. The Colonial Inn, an Ascend Collection Hotel

The Colonial Inn, an Ascend Collection Hotel
18.6 km from Duke Regional Hospital
United States
Rose
CA $155
CA $176 total
includes taxes & fees
Oct 11 - Oct 12
The Colonial Inn, an Ascend Collection Hotel
A modern lobby with a central seating area, a TV screen, and a patterned wall.
A modern hotel room with a bed, bedside table, TV, and a small desk area.
A modern kitchen with a built-in refrigerator, a gray sofa, and a gray armchair.
A reception area with a counter, a welcome sign, a digital screen, and a hallway leading to a dining area.

7. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek
18.2 km from Duke Regional Hospital
United States
Maurice
CA $168
CA $191 total
includes taxes & fees
Oct 18 - Oct 19
Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek
Pool
An outdoor dining area with tables and chairs, large windows, and a view of greenery.
A modern restaurant with long communal tables, hanging pendant lights, and geometric patterned walls.
A bar area with multiple shelves of bottles, glasses, and a bar counter.

8. The Westin Raleigh-Durham Airport

The Westin Raleigh-Durham Airport
18.2 km from Duke Regional Hospital
United States
Dina
CA $306
CA $347 total
includes taxes & fees
Oct 11 - Oct 12
The Westin Raleigh-Durham Airport
A couple walking through a hotel lobby with a modern design, including a reception desk and a wine display.
A modern reception area with a marble counter, a wooden bench, and a unique chandelier.
A modern kitchen with a central island, bar stools, wooden cabinets, and pendant lighting.
A modern bar area with a long counter, multiple bar stools, and a large screen displaying a sports event.

9. JB Duke Hotel

JB Duke Hotel
6.2 km from Duke Regional Hospital
United States
samantha
CA $305
CA $346 total
includes taxes & fees
Oct 18 - Oct 19
JB Duke Hotel
A spacious, elegantly decorated interior with a central round table, high ceilings, and classic architectural columns.
A spacious living room with a sofa, armchairs, a coffee table, and a chandelier.
A banquet hall with round tables, chandeliers, and floral centerpieces.
A large, historic building with a central courtyard, columns, and a brick facade.

10. The Carolina Inn, a Destination by Hyatt Hotel

The Carolina Inn, a Destination by Hyatt Hotel
19.9 km from Duke Regional Hospital
United States
Tony
CA $554
CA $629 total
includes taxes & fees
Nov 3 - Nov 4
The Carolina Inn, a Destination by Hyatt Hotel
An outdoor seating area with wicker furniture and a stone fire pit.
An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.
A conference room with a long table, chairs, and a modern chandelier.
A modern hotel lobby with seating areas, large windows, and a dining section.

11. Residence Inn Raleigh-Durham Airport/Brier Creek

Residence Inn Raleigh-Durham Airport/Brier Creek
16.6 km from Duke Regional Hospital
United States
Janet
CA $199
CA $225 total
includes taxes & fees
Oct 11 - Oct 12
Residence Inn Raleigh-Durham Airport/Brier Creek
A swimming pool with lounge chairs and a wooden fence.
A multi-story hotel with a modern design, featuring a prominent entrance with a glass canopy and an American flag.
A modern bar area with a refrigerated display, wooden bar counter, and seating.
A hotel room with a bed, a sofa, a desk with a chair, a television, and a painting on the wall.

12. Hyatt Place Durham Southpoint

Hyatt Place Durham Southpoint
16.1 km from Duke Regional Hospital
United States
Stephen
CA $192
CA $218 total
includes taxes & fees
Oct 21 - Oct 22
Hyatt Place Durham Southpoint
A spacious lobby with high ceilings, a central fountain, and seating areas.
A modern bedroom with a large bed, a fireplace, a walk-in closet, and a bathroom with a round mirror and vanity.
A bar area with multiple liquor cabinets and hanging pendant lights.
An outdoor patio area with wicker furniture, stone pillars, and string lights.

13. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

Embassy Suites by Hilton Raleigh Durham Airport Brier Creek
18.2 km from Duke Regional Hospital
United States
Darren C.
CA $227
CA $257 total
includes taxes & fees
Oct 18 - Oct 19
Embassy Suites by Hilton Raleigh Durham Airport Brier Creek
An outdoor seating area with wicker chairs and a large umbrella, a fire feature, and a view of the interior through glass walls.
A kitchen with a microwave, coffee maker, and a dishwasher.
A large indoor swimming pool with a skylight ceiling, clear glass walls, and a tiled floor.
A modern kitchen with a microwave, coffee maker, and dishwasher. There is a round table with two green chairs in front.

14. DoubleTree Suites by Hilton Raleigh - Durham

DoubleTree Suites by Hilton Raleigh - Durham
14.2 km from Duke Regional Hospital
United States
Stephen
CA $140
CA $159 total
includes taxes & fees
Nov 5 - Nov 6
DoubleTree Suites by Hilton Raleigh - Durham
A modern hotel with a prominent entrance, multiple floors, and a balcony on the second floor.
A modern hotel lobby with a reception desk, a beverage refrigerator, and a well-stocked snack bar.
A modern hotel room with a bed, a desk, a chair, a small seating area, and a kitchenette.
An outdoor patio with a fire feature, seating, and a building with large windows.

15. SpringHill Suites by Marriott Durham City View

SpringHill Suites by Marriott Durham City View
5.4 km from Duke Regional Hospital
United States
Taurean
CA $183
CA $208 total
includes taxes & fees
Nov 1 - Nov 2
SpringHill Suites by Marriott Durham City View
A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.
A bar area with a granite countertop, wooden chairs, and a large television screen.
An indoor swimming pool with clear glass walls, a tiled floor, and a seating area with chairs and a table.
A business center with wooden paneling, multiple workstations, and framed artwork on the walls.

16. Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center
9th Street District, 4 km from Duke Regional Hospital
United States
Hal
CA $197
CA $224 total
includes taxes & fees
Nov 2 - Nov 3
Hilton Garden Inn Durham/University Medical Center
Restaurant
An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.
A reception area with two wooden reception desks, a potted plant, and a computer on the wall.
A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

17. Courtyard Raleigh-Durham Airport/Brier Creek

Courtyard Raleigh-Durham Airport/Brier Creek
16.6 km from Duke Regional Hospital
United States
eidy
CA $191
CA $216 total
includes taxes & fees
Oct 18 - Oct 19
Courtyard Raleigh-Durham Airport/Brier Creek
An outdoor patio with wicker furniture, a stone fire pit, and a brick building in the background.
A spacious lobby with a reception desk, seating area, and a beverage kiosk.
A gym with treadmills, elliptical machines, a bench press, and a blue balance board.
A multi-story brick building with a modern entrance and a parking lot.

18. Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr
Trinity Park, 4.1 km from Duke Regional Hospital
United States
Patricia
CA $224
CA $255 total
includes taxes & fees
Nov 1 - Nov 2
Residence Inn Durham McPherson/Duke University Medical Cntr
Exterior
A modern interior with a kitchen area, dining space, and seating.
A compact kitchen with wooden cabinets, a black microwave, and a refrigerator. There are two chairs at a small island, and a flat-screen TV on a wooden stand.
A covered outdoor area with a symmetrical design, featuring a central seating area with chairs and a table, flanked by columns and potted plants.

19. Homewood Suites by Hilton Raleigh-Durham AP/Research Triangle

Homewood Suites by Hilton Raleigh-Durham AP/Research Triangle
17.3 km from Duke Regional Hospital
United States
Andrew
CA $157
CA $178 total
includes taxes & fees
Nov 1 - Nov 2
Homewood Suites by Hilton Raleigh-Durham AP/Research Triangle
A hotel dining area with round tables, chairs, and floral centerpieces.
A modern reception area with wooden flooring, a reception desk, and a glass partition.
A modern living room with a sofa, ottoman, coffee table, and a fireplace.
A well-lit store with shelves stocked with snacks, beverages, and bottled water.

20. Marriott Raleigh Durham Research Triangle Park

Marriott Raleigh Durham Research Triangle Park
16.6 km from Duke Regional Hospital
United States
Chase
CA $191
CA $217 total
includes taxes & fees
Nov 1 - Nov 2
Marriott Raleigh Durham Research Triangle Park
View all properties

Compare popular hotels close to Duke Regional Hospital

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.
Hampton Inn & Suites Durham/North I-85
9.0
Wonderful
1,003 reviews
View
A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.
Holiday Inn Express Durham by IHG
8.8
Excellent
1,004 reviews
View
A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.
Red Roof Inn Durham - Duke Univ Medical Center
6.8
1,002 reviews
View
A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.
Hampton Inn & Suites Durham University Medical Center
9.6
Exceptional
566 reviews
View
An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.
Fairfield by Marriott Inn & Suites Durham
9.6
Exceptional
55 reviews
View

Top Duke Regional Hospital Hotel Reviews

Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG

10/10 Excellent
"First of all the friendliness of the staff. The manager was outgoing and helpful. The staff even came around during breakfast and picked up the plates. The front desk knew the area and offered advice on how to get to restaurants and gave suggestions. The service was what you would find at an expensive large city hotel. Will certainly rebook when I return to the area."
Walter 2-night trip
Posted 1 hour ago
Holiday Inn Express Durham by IHG
Millennium Hotel Durham

Millennium Hotel Durham

10/10 Excellent
"Front desk couldn’t find my reservation. I called expedia and after more than an hour they emailed the hotel a new payment code. Gladly, Fernando, hotel front desk representative, was able to quickly make a new reservation and get me and my wife a room. Thanks Fernando (Millenium Hotel) for the great customer service."
Joao 2-night trip
Posted 6 hours ago
Millennium Hotel Durham
Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85

10/10 Excellent
"Clean rooms and friendly staff"
Darrel 5-night trip
Posted 12 hours ago
Hampton Inn & Suites Durham/North I-85
Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent
"The house was absolutely immaculate and Kristin could not have nicer or more helpful. The location was just 25 minutes from RDU, 12 minutes from downtown Durham and about a half an hour from Chapel Hill. Comfortable living room for my small group, large screen TV with all the streaming channels and a very cool coffee grinder/maker for regular or espresso coffee. Highly recommend. John L"
John L. 3-night trip
Posted 18 hours ago
Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit
Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University

8/10 Good
"Unsure"
Edwin L 1-night trip
Posted 1 day ago
Comfort Inn & Suites Durham near Duke University
Unscripted Durham, Part of JDV by Hyatt

Unscripted Durham, Part of JDV by Hyatt

10/10 Excellent
"Convenient"
Robert 1-night trip
Posted 2 days ago
Unscripted Durham, Part of JDV by Hyatt
The Lodge at Duke Medical Center

The Lodge at Duke Medical Center

10/10 Excellent
"My stay was great!"
Kenneth 1-night trip
Posted 8 days ago
The Lodge at Duke Medical Center
Drexall Haven - Stylish + Peaceful Stay

Drexall Haven - Stylish + Peaceful Stay

8/10 Good
"The house is newly renovated so everything looks really nice. The only issue I have is a lack of dressers for our clothes. Otherwise the experience was great. Quiet neighborhood out of the way but accessible."
willie M. 2-night trip
Posted 2 weeks ago
Drexall Haven - Stylish + Peaceful Stay
Everything within 1 mile

Everything within 1 mile

10/10 Excellent
"Perfect size and great location! The host has thought of everything and included so many extra thoughtful touches! So close to everything, quiet, clean, and stocked!"
Christine I. 3-night trip
Posted 1 month ago
Everything within 1 mile

Frequently asked questions

What's the area like around Duke Regional Hospital?
Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Duke Regional Hospital?
Courtyard Durham Near Duke University/Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.
How many hotels can I expect to find near Duke Regional Hospital?
Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.
If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?
Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.
What can I see and do near Duke Regional Hospital?
You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

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