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Our top choices for Duke Regional Hospital hotels

A conference room with a long table, chairs, and pendant lighting.
A large indoor swimming pool with clear blue water, surrounded by beige tiled flooring and walls, with large windows allowing natural light.
A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.
A narrow hallway with shelves stocked with snacks and beverages, leading to a room with a desk and chair.

1. Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85
2.2 km from Duke Regional Hospital
United States
Shwetha
CA $175
CA $198 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn & Suites Durham/North I-85
A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.
A gym with various exercise machines, a large mirror, and a television on the wall.
A Holiday Inn Express hotel with a modern design, featuring a prominent sign, multiple windows, and a well-lit entrance.
A breakfast buffet with a bakery section, a coffee station, and a sign indicating the availability of breakfast.

2. Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG
2.4 km from Duke Regional Hospital
United States
Kimberly R
CA $163
CA $184 total
includes taxes & fees
Nov 8 - Nov 9
Holiday Inn Express Durham by IHG
A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.
A spacious hallway with wooden flooring, white walls, and multiple windows with blinds. There are two white chairs and a small table with a basket.
A Red Roof Cafe with a stone wall, a coffee machine, and two white chairs.
A hotel room with a bed, bedside tables, a nightstand, a mirror, and a bathroom with a sink and mirror.

3. Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center
2.3 km from Duke Regional Hospital
United States
Luis
CA $89
CA $104 total
includes taxes & fees
Nov 2 - Nov 3
Red Roof Inn Durham - Duke Univ Medical Center
A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.
An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.
A modern dining area with a long table, multiple chairs, and a sofa with red ottomans.
A modern hotel lobby with a reception desk, seating area, and a cityscape mural on the wall.

4. Hampton Inn & Suites Durham University Medical Center

Hampton Inn & Suites Durham University Medical Center
5 km from Duke Regional Hospital
United States
Nicole
CA $181
CA $205 total
includes taxes & fees
Oct 25 - Oct 26
Hampton Inn & Suites Durham University Medical Center
A bar area with wooden bar stools, pendant lighting, and a counter with a glass display. There are tables and chairs in the background, and the room has a wooden floor.
A colonial-style building with a covered porch, multiple windows, and outdoor seating.
A bar area with wooden shelves, a chalkboard menu, and various bottles.
A hotel room with two beds, a sofa, a TV, and a bathroom visible through a door.

5. The Colonial Inn, an Ascend Collection Hotel

The Colonial Inn, an Ascend Collection Hotel
18.6 km from Duke Regional Hospital
United States
Elizabeth
CA $155
CA $176 total
includes taxes & fees
Oct 25 - Oct 26
The Colonial Inn, an Ascend Collection Hotel
A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.
A modern hotel lobby with a reception desk, seating area, and a cityscape mural on the wall.
An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.
A multi-story hotel with a prominent "HOME 2" sign, a brick facade, and a well-lit entrance.

6. Home2 Suites by Hilton Durham University Medical Center

Home2 Suites by Hilton Durham University Medical Center
5 km from Duke Regional Hospital
United States
katey
CA $205
CA $232 total
includes taxes & fees
Oct 29 - Oct 30
Home2 Suites by Hilton Durham University Medical Center
A modern lobby with a central seating area, a TV screen, and a patterned wall.
A modern kitchen with a built-in refrigerator, a gray sofa, and a gray armchair.
An indoor swimming pool with clear water, surrounded by lounge chairs and potted plants.
A modern hotel room with a bed, bedside table, TV, and a small desk area.

7. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek

Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek
18.2 km from Duke Regional Hospital
United States
Maurice
CA $168
CA $191 total
includes taxes & fees
Nov 8 - Nov 9
Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek
Pool
A bar area with multiple shelves of bottles, glasses, and a bar counter.
A modern living room with a pool table, a sofa, and a dining area.
An outdoor dining area with tables and chairs, large windows, and a view of greenery.

8. The Westin Raleigh-Durham Airport

The Westin Raleigh-Durham Airport
18.2 km from Duke Regional Hospital
United States
Dina
CA $307
CA $347 total
includes taxes & fees
Oct 18 - Oct 19
The Westin Raleigh-Durham Airport
A spacious lobby with high ceilings, a central fountain, and seating areas.
A modern bedroom with a large bed, a fireplace, a walk-in closet, and a bathroom with a round mirror and vanity.
A spacious lobby with a curved seating area, large windows, and a modern chandelier.
A bar area with multiple liquor cabinets and hanging pendant lights.

9. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

Embassy Suites by Hilton Raleigh Durham Airport Brier Creek
18.2 km from Duke Regional Hospital
United States
Darren C.
CA $227
CA $257 total
includes taxes & fees
Nov 8 - Nov 9
Embassy Suites by Hilton Raleigh Durham Airport Brier Creek
A brick pathway flanked by neatly trimmed hedges leading to a building with a red facade and a grey roof.
A spacious lobby with a long corridor, comfortable seating areas, and large windows providing natural light.
A modern living room with two sofas facing a glass coffee table, a large window with curtains, and a brick wall.
An outdoor dining area with tables set for four, surrounded by a brick pathway and lush greenery.

10. Rizzo Center, a Destination by Hyatt Hotel

Rizzo Center, a Destination by Hyatt Hotel
17 km from Duke Regional Hospital
United States
Dale
CA $263
CA $298 total
includes taxes & fees
Nov 1 - Nov 2
Rizzo Center, a Destination by Hyatt Hotel
A hotel entrance with a stone facade, large wooden doors, and a view into the interior.
A person performing a yoga pose outdoors with trees and a golf course in the background.
An indoor swimming pool with clear blue water, surrounded by lounge chairs and potted plants.
A dining area with a chandelier, tables, chairs, and a Christmas tree.

11. Washington Duke Inn & Golf Club

Washington Duke Inn & Golf Club
6.6 km from Duke Regional Hospital
United States
Lowell
CA $342
CA $388 total
includes taxes & fees
Oct 28 - Oct 29
Washington Duke Inn & Golf Club
A swimming pool with lounge chairs and a wooden fence.
A hotel room with a bed, a sofa, a desk with a chair, a television, and a painting on the wall.
A spacious lobby with a reception desk, seating area, and artwork on the walls.
A multi-story hotel with a modern design, featuring a prominent entrance with a glass canopy and an American flag.

12. Hyatt Place Durham Southpoint

Hyatt Place Durham Southpoint
16.1 km from Duke Regional Hospital
United States
Jessica
CA $192
CA $218 total
includes taxes & fees
Oct 22 - Oct 23
Hyatt Place Durham Southpoint
An indoor swimming pool with clear water, a no diving sign, and a seating area with chairs and tables.
A modern hotel lobby with a sectional sofa, armchairs, and a coffee table.
A modern hotel lobby with a reception desk, several chairs, a large monitor, and pendant lighting.
A modern hotel lobby with a long dining table, multiple chairs, a sofa, and a bar area.

13. Hyatt House Raleigh / RDU / Brier Creek

Hyatt House Raleigh / RDU / Brier Creek
17.8 km from Duke Regional Hospital
United States
Alton
CA $157
CA $178 total
includes taxes & fees
Nov 1 - Nov 2
Hyatt House Raleigh / RDU / Brier Creek
An outdoor seating area with wicker furniture and a stone fire pit.
A hotel lobby with a sofa, chairs, a table, and a large window offering a view of the building.
A modern hotel lobby with seating areas, large windows, and a dining section.
An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.

14. Residence Inn Raleigh-Durham Airport/Brier Creek

Residence Inn Raleigh-Durham Airport/Brier Creek
16.6 km from Duke Regional Hospital
United States
Janet
CA $199
CA $225 total
includes taxes & fees
Oct 18 - Oct 19
Residence Inn Raleigh-Durham Airport/Brier Creek
An outdoor patio with a table set for a meal, surrounded by chairs and a red umbrella.
A tented outdoor dining area with round tables set for a meal, each with white chairs and yellow tablecloths.
A bathroom with a granite countertop, a mirror, and a potted plant.
A hotel room with two beds, a desk, a mirror, a television, and a kitchenette.

15. DoubleTree Suites by Hilton Raleigh - Durham

DoubleTree Suites by Hilton Raleigh - Durham
14.2 km from Duke Regional Hospital
United States
Stephen
CA $147
CA $167 total
includes taxes & fees
Nov 5 - Nov 6
DoubleTree Suites by Hilton Raleigh - Durham
An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.
A modern kitchen with a central island, bar stools, wooden cabinets, and pendant lighting.
A modern living room with a fireplace, seating area, and a pool table.
A modern bar area with a long counter, multiple bar stools, and a large screen displaying a sports event.

16. JB Duke Hotel

JB Duke Hotel
6.2 km from Duke Regional Hospital
United States
samantha
CA $284
CA $322 total
includes taxes & fees
Oct 18 - Oct 19
JB Duke Hotel
A modern hotel with a prominent entrance, multiple floors, and a balcony on the second floor.
A modern hotel lobby with a reception desk, a beverage refrigerator, and a well-stocked snack bar.
An outdoor patio with a fire feature, seating, and a building with large windows.
A modern hotel room with a bed, a desk, a chair, a small seating area, and a kitchenette.

17. SpringHill Suites by Marriott Durham City View

SpringHill Suites by Marriott Durham City View
5.4 km from Duke Regional Hospital
United States
Taurean
CA $183
CA $208 total
includes taxes & fees
Oct 18 - Oct 19
SpringHill Suites by Marriott Durham City View
A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.
A bar area with a granite countertop, wooden chairs, and a large television screen.
An indoor swimming pool with clear glass walls, a tiled floor, and a seating area with chairs and a table.
A Hilton Garden Inn hotel with a modern design, featuring a large entrance and a parking area with a delivery van.

18. Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center
9th Street District, 4 km from Duke Regional Hospital
United States
Michael
CA $187
CA $212 total
includes taxes & fees
Nov 9 - Nov 10
Hilton Garden Inn Durham/University Medical Center
An outdoor patio with wicker furniture, a stone fire pit, and a brick building in the background.
A gym with treadmills, elliptical machines, a bench press, and a blue balance board.
A multi-story brick building with a modern entrance and a parking lot.
A hotel room with two beds, a desk, a TV, and a sofa.

19. Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr
Trinity Park, 4.1 km from Duke Regional Hospital
United States
Patricia
CA $212
CA $241 total
includes taxes & fees
Oct 18 - Oct 19
Residence Inn Durham McPherson/Duke University Medical Cntr
A spacious, elegantly decorated interior with a central round table, high ceilings, and classic architectural columns.
A banquet hall with round tables, chandeliers, and floral centerpieces.
A large, historic building with a central courtyard, columns, and a brick facade.
A spacious living room with a sofa, armchairs, a coffee table, and a chandelier.

20. The Carolina Inn, a Destination by Hyatt Hotel

The Carolina Inn, a Destination by Hyatt Hotel
19.9 km from Duke Regional Hospital
United States
Stephanie Pauline
CA $538
CA $611 total
includes taxes & fees
Nov 1 - Nov 2
The Carolina Inn, a Destination by Hyatt Hotel
View all properties

Compare popular hotels close to Duke Regional Hospital

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A conference room with a long table, chairs, and pendant lighting.
Hampton Inn & Suites Durham/North I-85
9.0
Wonderful
1,006 reviews
View
A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.
Holiday Inn Express Durham by IHG
8.8
Excellent
1,005 reviews
View
A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.
Red Roof Inn Durham - Duke Univ Medical Center
6.8
1,000 reviews
View
A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.
Hampton Inn & Suites Durham University Medical Center
9.6
Exceptional
572 reviews
View
A bar area with wooden bar stools, pendant lighting, and a counter with a glass display. There are tables and chairs in the background, and the room has a wooden floor.
The Colonial Inn, an Ascend Collection Hotel
9.6
Exceptional
322 reviews
View

Top Duke Regional Hospital Hotel Reviews

Hilton Durham near Duke University

Hilton Durham near Duke University

10/10 Excellent
"Good location and has all ameneties for a comfortable stay"
Samiksha 3-night trip
Posted 3 hours ago
Hilton Durham near Duke University
Courtyard Durham Near Duke University/Downtown

Courtyard Durham Near Duke University/Downtown

10/10 Excellent
"I want to personally thank "HEIDI", the front desk staff person. She was fantatstic in every way. She went the extra mile to help us check in early and made sure we were accommodated. Please commend her."
Kevin 2-night trip
Posted 8 hours ago
Courtyard Durham Near Duke University/Downtown
Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85

10/10 Excellent
"Very clean room, and friendly staff"
Shwetha 2-night trip
Posted 17 hours ago
Hampton Inn & Suites Durham/North I-85
Everything within 1 mile

Everything within 1 mile

10/10 Excellent
"This home is thoughtfully laid out and much more spacious than it looks in photos. Our kids enjoyed the snacks each night, and their grandma loved that the home is all one level with smooth floors and bright lighting. Location was perfect for attending events in Durham, Wake Forest and Raleigh. There's also a running path across the street."
Talita M. 3-night trip
Posted 1 day ago
Everything within 1 mile
The Lodge at Duke Medical Center

The Lodge at Duke Medical Center

8/10 Good
"Very convenient to the medical center and university. The staff was very helpful. Good value. Very safe."
Malini 3-night trip
Posted 1 day ago
The Lodge at Duke Medical Center
Unscripted Durham, Part of JDV by Hyatt

Unscripted Durham, Part of JDV by Hyatt

8/10 Good
"The place was awesome! I'm not going into details....I came home with some bed bug bites......🤔"
Randell 1-night trip
Posted 2 days ago
Unscripted Durham, Part of JDV by Hyatt
21c Museum Hotel Durham

21c Museum Hotel Durham

10/10 Excellent
"Stellar customer service!! Look elsewhere for food."
James 3-night trip
Posted 4 days ago
21c Museum Hotel Durham
Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent
"The house was absolutely immaculate and Kristin could not have nicer or more helpful. The location was just 25 minutes from RDU, 12 minutes from downtown Durham and about a half an hour from Chapel Hill. Comfortable living room for my small group, large screen TV with all the streaming channels and a very cool coffee grinder/maker for regular or espresso coffee. Highly recommend. John L"
John L. 3-night trip
Posted 8 days ago
Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit
Cottage with Yard, Mins to Duke

Cottage with Yard, Mins to Duke

10/10 Excellent
"This was a cheerful home with comfortable beds and many thoughtful extras. We enjoyed our time here."
Mary and Richard D. 2-night trip
Posted 2 months ago
Cottage with Yard, Mins to Duke

Frequently asked questions

What's the area like around Duke Regional Hospital?
Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Duke Regional Hospital?
Courtyard Durham Near Duke University/Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.
How many hotels can I expect to find near Duke Regional Hospital?
Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.
If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?
Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.
What can I see and do near Duke Regional Hospital?
You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

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