---
title: "The 10 Best Hotels Near Duke Regional Hospital, Raleigh from CA $89 | Expedia.ca"
description: "Stay close to Duke Regional Hospital. Book the best hotels near Duke Regional Hospital in Raleigh from CA $89. Compare room rates, hotel reviews and availability. Most hotels are fully refundable."
canonical: "https://www.expedia.ca/Duke-Regional-Hospital-Hotels.0-l553248633992437561-0.Travel-Guide-Filter-Hotels"
language: en-CA
market: CA
currency: CAD
prices_as_of: 2026-11-14T13:47:30Z
---

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# Find hotels near Duke Regional Hospital, Raleigh from CA $89
![Mature patient, doctor and tablet for healthcare, support or conversation with checkup appointment in office. Female person, medical professional and diagnosis talk for senior woman at clinic](https://images.trvl-media.com/place_category/urn:expe:taxo:media-place-category-fallbacks:medicalCenter/071ecc08-f07b-4743-bfe4-4da99aa0a06d.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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[Check prices for these dates, December 14–15, 2026](https://www.expedia.ca/Hotel-Search?regionId=553248633992437561&startDate=2026-12-14&endDate=2026-12-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

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## Our top choices for Duke Regional Hospital hotels

### [1\. Hampton Inn & Suites Durham/North I-85](https://www.expedia.ca/Raleigh-Hotels-Hampton-Inn-Suites-Durham-North-I-85.h4640309.Hotel-Information)

![A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/5d825f74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

- Location: 2.2 km from Duke Regional Hospital
- Guest rating: 9/10 (Wonderful, 1000 reviews)
- Price: CA $175, CA $198 total, includes taxes & fees, Nov 22 - Nov 23, for Our top choices for Duke Regional Hospital hotels
- Review: Staffing was great and rooms clean, by Mitzie

### [2\. Red Roof Inn Durham - Duke Univ Medical Center](https://www.expedia.ca/Raleigh-Hotels-Red-Roof-Inn-Durham-Duke-University-Medical-Center.h12096.Hotel-Information)

![A Red Roof Inn lobby with a stone wall, wooden flooring, and a seating area with chairs and a small table.](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/4dd168a1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 2.3 km from Duke Regional Hospital
- Guest rating: 6.8/10 (1001 reviews)
- Price: CA $89, CA $104 total, includes taxes & fees, Nov 22 - Nov 23, for Our top choices for Duke Regional Hospital hotels
- Review: Excellent, by Sinjin

### [3\. Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek](https://www.expedia.ca/Raleigh-Hotels-Hampton-Inn-Suites-Raleigh-Durham-Airport-Brier-Creek.h1717373.Hotel-Information)

![A modern lobby with a central seating area, a TV screen, and a patterned wall.](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717373/e05094b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 18.2 km from Duke Regional Hospital
- Guest rating: 9.4/10 (Exceptional, 1001 reviews)
- Price: CA $163, CA $184 total, includes taxes & fees, Nov 28 - Nov 29, for Our top choices for Duke Regional Hospital hotels
- Review: Great place, by Justin

### [4\. Hilton Durham near Duke University](https://www.expedia.ca/Raleigh-Hotels-Hilton-Durham-Near-Duke-University.h18821.Hotel-Information)

![Pool](https://images.trvl-media.com/lodging/1000000/20000/18900/18821/09c549f7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 5.4 km from Duke Regional Hospital
- Guest rating: 8.8/10 (Excellent, 1029 reviews)
- Price: CA $151, CA $171 total, includes taxes & fees, Nov 23 - Nov 24, for Our top choices for Duke Regional Hospital hotels
- Review: Great stay, by Thien

### [5\. Hampton Inn & Suites Durham University Medical Center](https://www.expedia.ca/Raleigh-Hotels-Hampton-Inn-Suites-DurhamNorth-CampusMedical-Center.h92816799.Hotel-Information)

![A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816799/984d892a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 5 km from Duke Regional Hospital
- Guest rating: 9.6/10 (Exceptional, 598 reviews)
- Price: CA $162, CA $184 total, includes taxes & fees, Dec 13 - Dec 14, for Our top choices for Duke Regional Hospital hotels
- Review: Everything was great, front desk check in, room clean., by LaGrant

### [6\. Fairfield by Marriott Inn & Suites Durham](https://www.expedia.ca/Raleigh-Hotels-Fairfield-By-Marriott-Inn-Suites-Durham.h120670.Hotel-Information)

![A modern living room with a fireplace, large windows, and hanging pendant lights.](https://images.trvl-media.com/lodging/1000000/130000/120700/120670/3af9c119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 18.2 km from Duke Regional Hospital
- Guest rating: 9.6/10 (Exceptional, 72 reviews)
- Price: CA $132, CA $150 total, includes taxes & fees, Nov 26 - Nov 27, for Our top choices for Duke Regional Hospital hotels
- Review: Perfect location to visit Raleigh/Durham. Very nice hotel, great value!, by Preston

### [7\. University Inn Durham next to Duke University Medical Center](https://www.expedia.ca/Raleigh-Hotels-University-Inn-Durham-Next-To-Duke-University-Medical-Center.h1464431.Hotel-Information)

![A building with a sign reading "Morris Cancer Clinic" and a bench outside.](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/bbe154ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 4.5 km from Duke Regional Hospital
- Guest rating: 9/10 (Wonderful, 1005 reviews)
- Price: CA $153, CA $173 total, includes taxes & fees, Nov 25 - Nov 26, for Our top choices for Duke Regional Hospital hotels
- Review: Great location and prices, by William

### [8\. JB Duke Hotel](https://www.expedia.ca/Raleigh-Hotels-JB-Duke-Hotel.h15935986.Hotel-Information)

![An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.](https://images.trvl-media.com/lodging/16000000/15940000/15936000/15935986/0914b52f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 6.2 km from Duke Regional Hospital
- Guest rating: 9.4/10 (Exceptional, 755 reviews)
- Price: CA $258, CA $293 total, includes taxes & fees, Nov 30 - Dec 1, for Our top choices for Duke Regional Hospital hotels
- Review: Clean, great shampoo/ shower products, welcome my small service dog. Great quiet location., by David Elliott

### [9\. Hyatt House Raleigh / RDU / Brier Creek](https://www.expedia.ca/Raleigh-Hotels-Hyatt-House-Raleigh-RDU-Brier-Creek.h17313661.Hotel-Information)

![A modern kitchen with built-in shelves, a glass backsplash, and a variety of kitchenware.](https://images.trvl-media.com/lodging/18000000/17320000/17313700/17313661/700fb320.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 17.8 km from Duke Regional Hospital
- Guest rating: 9.2/10 (Wonderful, 1003 reviews)
- Price: CA $156, CA $177 total, includes taxes & fees, Nov 22 - Nov 23, for Our top choices for Duke Regional Hospital hotels
- Review: Great breakfast, friendly staff, by Dewayne G.

### [10\. DoubleTree Suites by Hilton Raleigh - Durham](https://www.expedia.ca/Raleigh-Hotels-DoubleTree-Suites-By-Hilton-Raleigh-Durham.h13139.Hotel-Information)

![A spacious indoor dining area with high ceilings, large windows, and modern furniture.](https://images.trvl-media.com/lodging/1000000/20000/13200/13139/12ba2c20.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 14.2 km from Duke Regional Hospital
- Guest rating: 9.2/10 (Wonderful, 1004 reviews)
- Price: CA $164, CA $186 total, includes taxes & fees, Nov 23 - Nov 24, for Our top choices for Duke Regional Hospital hotels
- Review: Would stay again., by Sierra

### [11\. Hilton Garden Inn Durham/University Medical Center](https://www.expedia.ca/Raleigh-Hotels-Hilton-Garden-Inn-DurhamUniversity-Medical-Center.h6232983.Hotel-Information)

![A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.](https://images.trvl-media.com/lodging/7000000/6240000/6233000/6232983/9047a750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 9th Street District, 4 km from Duke Regional Hospital
- Guest rating: 9.2/10 (Wonderful, 1000 reviews)
- Price: CA $173, CA $197 total, includes taxes & fees, Dec 11 - Dec 12, for Our top choices for Duke Regional Hospital hotels
- Review: Location, by cindy

### [12\. Comfort Inn & Suites Durham near Duke University](https://www.expedia.ca/Raleigh-Hotels-Comfort-Inn-Suites-Durham-Near-Duke-University.h12352.Hotel-Information)

![A restaurant with a large ice dispenser, wooden paneling, and red cushioned booths.](https://images.trvl-media.com/lodging/1000000/20000/12400/12352/fd344660.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Croasdaile Farm Master, 3.3 km from Duke Regional Hospital
- Guest rating: 8.6/10 (Excellent, 1215 reviews)
- Price: CA $135, CA $153 total, includes taxes & fees, Dec 6 - Dec 7, for Our top choices for Duke Regional Hospital hotels
- Review: Good room and breakfast, by Robert

### [13\. Washington Duke Inn & Golf Club](https://www.expedia.ca/Raleigh-Hotels-Washington-Duke-Inn-Golf-Club.h10844.Hotel-Information)

![A hotel with a stone lion statue, a covered entrance, and a landscaped garden.](https://images.trvl-media.com/lodging/1000000/20000/10900/10844/7e33e583.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 6.6 km from Duke Regional Hospital
- Guest rating: 9.6/10 (Exceptional, 1001 reviews)
- Price: CA $342, CA $389 total, includes taxes & fees, Nov 18 - Nov 19, for Our top choices for Duke Regional Hospital hotels
- Review: Location., by James

### [14\. Homewood Suites by Hilton Raleigh-Durham AP/Research Triangle](https://www.expedia.ca/Raleigh-Hotels-Homewood-Suites-Raleigh-Durham-Airport.h154428.Hotel-Information)

![A spacious lobby with a reception desk, a central seating area with a round table and chairs, and a staircase leading to an upper level.](https://images.trvl-media.com/lodging/1000000/160000/154500/154428/33cdf1a4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 17.3 km from Duke Regional Hospital
- Guest rating: 9/10 (Wonderful, 739 reviews)
- Price: CA $156, CA $178 total, includes taxes & fees, Dec 5 - Dec 6, for Our top choices for Duke Regional Hospital hotels
- Review: The rooms were a nice size., by Bethany

### [15\. Courtyard Durham Near Duke University/Downtown](https://www.expedia.ca/Raleigh-Hotels-Courtyard-By-Marriott-Durham.h42705.Hotel-Information)

![An outdoor patio with a stone fire pit surrounded by wicker furniture and a large window overlooking the building.](https://images.trvl-media.com/lodging/1000000/50000/42800/42705/6d146009.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Croasdaile Farm Master, 3.5 km from Duke Regional Hospital
- Guest rating: 8.2/10 (Very good, 1004 reviews)
- Price: CA $132, CA $150 total, includes taxes & fees, Nov 23 - Nov 24, for Our top choices for Duke Regional Hospital hotels
- Review: This hotel is clean and quiet, we had a restful stay., by Lynn

### [16\. La Quinta Inn & Suites by Wyndham Univ Area Chapel Hill](https://www.expedia.ca/Raleigh-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Univ-Area-Chapel-Hill.h165760.Hotel-Information)

![A modern living room with a fireplace, comfortable seating, and a large window with curtains.](https://images.trvl-media.com/lodging/1000000/170000/165800/165760/adc70ef4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: North Garrett Road, 10.4 km from Duke Regional Hospital
- Guest rating: 8.8/10 (Excellent, 1956 reviews)
- Price: CA $117, CA $133 total, includes taxes & fees, Nov 29 - Nov 30, for Our top choices for Duke Regional Hospital hotels
- Review: The room was clean, staff was great, by Kelly

### [17\. Courtyard Raleigh-Durham Airport/Brier Creek](https://www.expedia.ca/Raleigh-Hotels-Courtyard-Raleigh-Durham-AirportBrier-Creek.h10360583.Hotel-Information)

![A buffet area with a variety of fruits, vegetables, and baked goods.](https://images.trvl-media.com/lodging/11000000/10370000/10360600/10360583/108aaaa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 16.6 km from Duke Regional Hospital
- Guest rating: 9.2/10 (Wonderful, 1000 reviews)
- Price: CA $185, CA $209 total, includes taxes & fees, Nov 22 - Nov 23, for Our top choices for Duke Regional Hospital hotels
- Review: Awesome stay, by Sherrise

### [18\. AC Hotel Durham](https://www.expedia.ca/Raleigh-Hotels-AC-Hotel-Durham.h66794113.Hotel-Information)

![A modern hotel room with a large window, a sofa, a chair, and a coffee table with a decorative bowl.](https://images.trvl-media.com/lodging/67000000/66800000/66794200/66794113/258a1fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 5.4 km from Duke Regional Hospital
- Guest rating: 9/10 (Wonderful, 724 reviews)
- Price: CA $185, CA $210 total, includes taxes & fees, Nov 22 - Nov 23, for Our top choices for Duke Regional Hospital hotels
- Review: Enjoyed my stay, by Raphael

### [19\. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek](https://www.expedia.ca/Raleigh-Hotels-Embassy-Suites-Raleigh-Durham-AirportBrier-Creek.h2967293.Hotel-Information)

![A spacious lobby with high ceilings, a central fountain, and seating areas.](https://images.trvl-media.com/lodging/3000000/2970000/2967300/2967293/a0f542e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 18.2 km from Duke Regional Hospital
- Guest rating: 9.2/10 (Wonderful, 1002 reviews)
- Price: CA $204, CA $231 total, includes taxes & fees, Dec 13 - Dec 14, for Our top choices for Duke Regional Hospital hotels
- Review: Easily the best stay in the area., by William

### [20\. Holiday Inn Express & Suites Raleigh Airport - Brier Creek by IHG](https://www.expedia.ca/Raleigh-Hotels-Holiday-Inn-Express-Suites-Raleigh-Airport-Brier-Creek.h23160649.Hotel-Information)

![A buffet with labeled containers of turkey sausage and cookies.](https://images.trvl-media.com/lodging/24000000/23170000/23160700/23160649/3cc9dc36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: 16.9 km from Duke Regional Hospital
- Guest rating: 8.8/10 (Excellent, 1003 reviews)
- Price: CA $131, CA $156 total, includes taxes & fees, Dec 14 - Dec 15, for Our top choices for Duke Regional Hospital hotels
- Review: Great breakfast and room., by Carol

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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## Compare popular hotels close to Duke Regional Hospital

| Property                                                                                                                                                                                                                                                                                                                | Star rating                 | Guest rating | Breakfast included | Pool | Spa | Pet-friendly | WiFi included |
| ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- | --------------------------- | ------------ | ------------------ | ---- | --- | ------------ | ------------- |
| ![A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/5d825f74.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hampton Inn & Suites Durham/North I-85   | 9.0Wonderful1,000 reviews   | View         |                    |      |     |              |               |
| ![A Red Roof Inn lobby with a stone wall, wooden flooring, and a seating area with chairs and a small table.](https://images.trvl-media.com/lodging/1000000/20000/12100/12096/4dd168a1.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Red Roof Inn Durham - Duke Univ Medical Center                                       | 6.81,001 reviews            | View         |                    |      |     |              |               |
| ![A modern lobby with a central seating area, a TV screen, and a patterned wall.](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717373/e05094b4.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek                                                    | 9.4Exceptional1,001 reviews | View         |                    |      |     |              |               |
| ![Pool](https://images.trvl-media.com/lodging/1000000/20000/18900/18821/09c549f7.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hilton Durham near Duke University                                                                                                                                                         | 8.8Excellent1,029 reviews   | View         |                    |      |     |              |               |
| ![A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816799/984d892a.jpg?impolicy=fcrop&w=900&h=675&p=1&q=medium)Hampton Inn & Suites Durham University Medical Center | 9.6Exceptional598 reviews   | View         |                    |      |     |              |               |

## Top Duke Regional Hospital Hotel Reviews

### [Hampton Inn & Suites Durham University Medical Center](https://www.expedia.ca/Raleigh-Hotels-Hampton-Inn-Suites-DurhamNorth-CampusMedical-Center.h92816799.Hotel-Information)

![A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.](https://images.trvl-media.com/lodging/93000000/92820000/92816800/92816799/984d892a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 1206 Cole Mill Road, Durham, NC, 27705, US
- Location: Durham
- Star rating: 2.5/5
- Guest rating: 9.6/10 (598 reviews)
- Review: Close to Duke campus., by Bellanne, April 6, 2025, rated 10/10 Excellent

### [JB Duke Hotel](https://www.expedia.ca/Raleigh-Hotels-JB-Duke-Hotel.h15935986.Hotel-Information)

![An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.](https://images.trvl-media.com/lodging/16000000/15940000/15936000/15935986/0914b52f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 230 Science Drive, Durham, NC, 27708, US
- Location: Durham
- Star rating: 4/5
- Guest rating: 9.4/10 (755 reviews)
- Review: Great location, super convenient to university, great staff and clean room., by Sophia, July 22, 2026, rated 10/10 Excellent

### [Hilton Garden Inn Durham/University Medical Center](https://www.expedia.ca/Raleigh-Hotels-Hilton-Garden-Inn-DurhamUniversity-Medical-Center.h6232983.Hotel-Information)

![A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.](https://images.trvl-media.com/lodging/7000000/6240000/6233000/6232983/9047a750.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 2102 West Main Street, Durham, NC, 27705, US
- Location: 9th Street District
- Star rating: 3/5
- Guest rating: 9.2/10 (1000 reviews)
- Review: Super clean. Very nice hotel, by David, March 30, 2024, rated 10/10 Excellent

### [Fairfield by Marriott Inn & Suites Durham](https://www.expedia.ca/Raleigh-Hotels-Fairfield-By-Marriott-Inn-Suites-Durham.h120670.Hotel-Information)

![A modern living room with a fireplace, large windows, and hanging pendant lights.](https://images.trvl-media.com/lodging/1000000/130000/120700/120670/3af9c119.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 5219 Page Rd, Durham, NC, 27703, US
- Location: Durham
- Star rating: 3/5
- Guest rating: 9.6/10 (72 reviews)
- Review: Nice Spot!, by Sandy Golfetto, September 4, 2026, rated 10/10 Excellent

### [Hampton Inn & Suites Durham/North I-85](https://www.expedia.ca/Raleigh-Hotels-Hampton-Inn-Suites-Durham-North-I-85.h4640309.Hotel-Information)

![A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.](https://images.trvl-media.com/lodging/5000000/4650000/4640400/4640309/5d825f74.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 1542 North Gregson Street, Durham, NC, 27701, US
- Location: Durham
- Star rating: 2.5/5
- Guest rating: 9/10 (1000 reviews)
- Review: Great place to stay a few days. Very nice staff, by Mohammadreza, August 15, 2024, rated 10/10 Excellent

### [University Inn Durham next to Duke University Medical Center](https://www.expedia.ca/Raleigh-Hotels-University-Inn-Durham-Next-To-Duke-University-Medical-Center.h1464431.Hotel-Information)

![A building with a sign reading "Morris Cancer Clinic" and a bench outside.](https://images.trvl-media.com/lodging/2000000/1470000/1464500/1464431/bbe154ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 502 Elf St, Durham, NC, 27705, US
- Location: Durham
- Star rating: 2/5
- Guest rating: 9/10 (1005 reviews)
- Review: A very convenient place for hospital visitors with kind and helpful staff., by Mengjie, July 18, 2026, rated 10/10 Excellent

### [Hampton Inn & Suites Raleigh-Durham Airport-Brier Creek](https://www.expedia.ca/Raleigh-Hotels-Hampton-Inn-Suites-Raleigh-Durham-Airport-Brier-Creek.h1717373.Hotel-Information)

![A modern lobby with a central seating area, a TV screen, and a patterned wall.](https://images.trvl-media.com/lodging/2000000/1720000/1717400/1717373/e05094b4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 8021 Arco Corporate Drive, Raleigh, NC, 27617, US
- Location: Raleigh
- Star rating: 2.5/5
- Guest rating: 9.4/10 (1001 reviews)
- Review: bien, by Jimmy, August 31, 2026, rated 10/10 Excellent

### [Residence Inn Durham McPherson/Duke University Medical Cntr](https://www.expedia.ca/Raleigh-Hotels-Residence-Inn-Durham-McPhersonDuke-University-Medical-Cntr.h10344567.Hotel-Information)

![A spacious lobby with a reception desk, seating area, and a beverage kiosk.](https://images.trvl-media.com/lodging/11000000/10350000/10344600/10344567/c90f9818.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Trinity Park
- Review: Was very nice. The staff was very polite when we arrived., by Derek, August 5, 2025, rated 10/10 Excellent

### [AC Hotel Durham](https://www.expedia.ca/Raleigh-Hotels-AC-Hotel-Durham.h66794113.Hotel-Information)

![A modern hotel room with a large window, a sofa, a chair, and a coffee table with a decorative bowl.](https://images.trvl-media.com/lodging/67000000/66800000/66794200/66794113/258a1fd6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Address: 2800 Erwin Road, Durham, NC, 27705, US
- Location: Durham
- Star rating: 3/5
- Guest rating: 9/10 (724 reviews)
- Review: Modern hotel, clean, comfortable beds., by Valia, April 8, 2026, rated 10/10 Excellent

### [Holiday Inn Express Durham by IHG](https://www.expedia.ca/Raleigh-Hotels-Holiday-Inn-Express-Durham.h519791.Hotel-Information)

![A hotel room with two beds, a TV, a desk, and a mirror.](https://images.trvl-media.com/lodging/1000000/520000/519800/519791/98c55f94.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Durham
- Review: Very comfy the staff were very nice and accommodating., by Joanne, November 10, 2024, rated 10/10 Excellent

### [The Durham Hotel](https://www.expedia.ca/Raleigh-Hotels-The-Durham-Hotel.h10995456.Hotel-Information)

![A spacious lobby with a curved ceiling, large windows, and a variety of seating arrangements including sofas, tables, and chairs.](https://images.trvl-media.com/lodging/11000000/11000000/10995500/10995456/6ad3b381.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Downtown Durham
- Review: The key to this hotel is the location in the heart of downtown Durham. It was a quick Uber ride for us to go anywhere, including the Duke game at Cameron Indoor Arena. Lots of good places to eat nearby. The staff was friendly and accommodating. The room was large and suited our needs. We enjoyed our stay and would happily return to The Durham Hotel., by Michael, March 10, 2026, rated 10/10 Excellent

### [Tru by Hilton Raleigh Durham Airport](https://www.expedia.ca/Raleigh-Hotels-Tru-By-Hilton-Raleigh-Durham-Airport.h22789172.Hotel-Information)

![A modern lounge area with a pool table, seating, and beverage dispensers.](https://images.trvl-media.com/lodging/23000000/22790000/22789200/22789172/3d965c75.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)
- Location: Morrisville
- Review: 👍 clean and nice, by song, August 2, 2026, rated 10/10 Excellent

## Frequently Asked Questions

### What's the area like around Duke Regional Hospital?

Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.

### Where is the best place to stay close to Duke Regional Hospital?

[Courtyard Durham Near Duke University/Downtown](https://www.expedia.ca/Raleigh-Hotels-Courtyard-By-Marriott-Durham.h42705.Hotel-Information) is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include [Holiday Inn Express Durham by IHG](https://www.expedia.ca/Raleigh-Hotels-Holiday-Inn-Express-Durham.h519791.Hotel-Information) and [Red Roof Inn Durham - Duke Univ Medical Center](https://www.expedia.ca/Raleigh-Hotels-Red-Roof-Inn-Durham-Duke-University-Medical-Center.h12096.Hotel-Information).

### How many hotels can I expect to find near Duke Regional Hospital?

Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.

### If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?

Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.

### Where can I learn more about changing or cancelling my trip in the area near Duke Regional Hospital?

To find more details about changing or cancelling your stay near Duke Regional Hospital, [click here](https://www.expedia.com/service/).

### What can I see and do near Duke Regional Hospital?

You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

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