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Our top choices for Duke Regional Hospital hotels

A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.
A narrow hallway with shelves stocked with snacks and beverages, leading to a room with a desk and chair.
A Hampton Inn hotel with a modern facade, multiple floors, and a parking lot.
A hotel room with a bed, a desk with a chair, a flat-screen TV, a microwave, and a mirror.

1. Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85
2.2 km from Duke Regional Hospital
United States
Cindy
CA $168
CA $191 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn & Suites Durham/North I-85
A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.
A Holiday Inn Express hotel with a modern design, featuring a prominent sign, multiple windows, and a well-lit entrance.
A coffee station with two coffee machines, a coffee press, and various coffee-related items on a counter.
A gym with various exercise machines, a large mirror, and a television on the wall.

2. Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG
2.4 km from Duke Regional Hospital
United States
Kimberly R
CA $165
CA $188 total
includes taxes & fees
Nov 1 - Nov 2
Holiday Inn Express Durham by IHG
A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.
A Red Roof Inn with a modern architectural design, featuring a prominent red sign and a well-maintained lawn.
A hotel room with a bed, bedside tables, a nightstand, a mirror, and a bathroom with a sink and mirror.
A Red Roof Cafe with a stone wall, a coffee machine, and two white chairs.

3. Red Roof Inn Durham - Duke Univ Medical Center

Red Roof Inn Durham - Duke Univ Medical Center
2.3 km from Duke Regional Hospital
United States
Luis
CA $89
CA $104 total
includes taxes & fees
Oct 11 - Oct 12
Red Roof Inn Durham - Duke Univ Medical Center
A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.
A modern dining area with a long table, multiple chairs, and a sofa with red ottomans.
A Hampton Inn & Suites hotel with a modern facade, multiple windows, and a parking lot.
An indoor swimming pool with clear blue water, surrounded by lounge chairs and a tiled floor.

4. Hampton Inn & Suites Durham University Medical Center

Hampton Inn & Suites Durham University Medical Center
5 km from Duke Regional Hospital
United States
Nicole
CA $178
CA $202 total
includes taxes & fees
Nov 1 - Nov 2
Hampton Inn & Suites Durham University Medical Center
An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.
A modern living room with a fireplace, two sofas, a coffee table, and a TV mounted on the wall.
A hotel room with two beds, a desk, a chair, a sofa, and a TV.
A modern restaurant with round tables and yellow chairs, a bar area, and a 'Hello Fall' sign.

5. Fairfield by Marriott Inn & Suites Durham

Fairfield by Marriott Inn & Suites Durham
18.2 km from Duke Regional Hospital
United States
Yolanda
CA $169
CA $192 total
includes taxes & fees
Oct 23 - Oct 24
Fairfield by Marriott Inn & Suites Durham
A bar area with wooden bar stools, pendant lighting, and a counter with a glass display. There are tables and chairs in the background, and the room has a wooden floor.
A hotel room with two beds, a sofa, a TV, and a bathroom visible through a door.
A bar area with wooden shelves, a chalkboard menu, and various bottles.
A colonial-style building with a covered porch, multiple windows, and outdoor seating.

6. The Colonial Inn, an Ascend Collection Hotel

The Colonial Inn, an Ascend Collection Hotel
18.6 km from Duke Regional Hospital
United States
Rose
CA $155
CA $176 total
includes taxes & fees
Oct 11 - Oct 12
The Colonial Inn, an Ascend Collection Hotel
Pool
A bar area with multiple shelves of bottles, glasses, and a bar counter.
A modern restaurant with long communal tables, hanging pendant lights, and geometric patterned walls.
A modern living room with a pool table, a sofa, and a dining area.

7. The Westin Raleigh-Durham Airport

The Westin Raleigh-Durham Airport
18.2 km from Duke Regional Hospital
United States
Dina
CA $306
CA $347 total
includes taxes & fees
Oct 11 - Oct 12
The Westin Raleigh-Durham Airport
An outdoor seating area with sofas, chairs, and a fire pit, adjacent to a modern building with large windows.
A modern bar area with a long counter, multiple bar stools, and a large screen displaying a sports event.
A modern living room with a fireplace, seating area, and a pool table.
A modern reception area with a marble counter, a wooden bench, and a unique chandelier.

8. JB Duke Hotel

JB Duke Hotel
6.2 km from Duke Regional Hospital
United States
samantha
CA $299
CA $340 total
includes taxes & fees
Oct 18 - Oct 19
JB Duke Hotel
An outdoor seating area with wicker furniture and a stone fire pit.
A modern hotel lobby with seating areas, large windows, and a dining section.
A hotel lobby with a sofa, chairs, a table, and a large window offering a view of the building.
An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.

9. Residence Inn Raleigh-Durham Airport/Brier Creek

Residence Inn Raleigh-Durham Airport/Brier Creek
16.6 km from Duke Regional Hospital
United States
Janet
CA $199
CA $225 total
includes taxes & fees
Oct 11 - Oct 12
Residence Inn Raleigh-Durham Airport/Brier Creek
A spacious, elegantly decorated interior with a central round table, high ceilings, and classic architectural columns.
A well-lit living room with a sofa, armchairs, a coffee table, and a fireplace.
A banquet hall with round tables, chandeliers, and floral centerpieces.
A large, historic building with a central courtyard, columns, and a brick facade.

10. The Carolina Inn, a Destination by Hyatt Hotel

The Carolina Inn, a Destination by Hyatt Hotel
19.9 km from Duke Regional Hospital
United States
Tony
CA $554
CA $629 total
includes taxes & fees
Nov 3 - Nov 4
The Carolina Inn, a Destination by Hyatt Hotel
A swimming pool with lounge chairs and a wooden fence.
A modern bar area with a refrigerated display, wooden bar counter, and seating.
A hotel room with a bed, a sofa, a desk with a chair, a television, and a painting on the wall.
A spacious lobby with a reception desk, seating area, and artwork on the walls.

11. Hyatt Place Durham Southpoint

Hyatt Place Durham Southpoint
16.1 km from Duke Regional Hospital
United States
Stephen
CA $192
CA $218 total
includes taxes & fees
Oct 11 - Oct 12
Hyatt Place Durham Southpoint
An outdoor seating area with wicker chairs and a large umbrella, a fire feature, and a view of the interior through glass walls.
A modern kitchen with a microwave, coffee maker, and dishwasher. There is a round table with two green chairs in front.
A large indoor swimming pool with a skylight ceiling, clear glass walls, and a tiled floor.
A hotel room with a large bed, a bedside table with a lamp, a TV mounted on the wall, and a window with curtains.

12. DoubleTree Suites by Hilton Raleigh - Durham

DoubleTree Suites by Hilton Raleigh - Durham
14.2 km from Duke Regional Hospital
United States
Stephen
CA $139
CA $158 total
includes taxes & fees
Oct 11 - Oct 12
DoubleTree Suites by Hilton Raleigh - Durham
A spacious lobby with high ceilings, a central fountain, and seating areas.
A modern bedroom with a large bed, a fireplace, a walk-in closet, and a bathroom with a round mirror and vanity.
A spacious lobby with a curved seating area, large windows, and a modern chandelier.
A bar area with multiple liquor cabinets and hanging pendant lights.

13. Embassy Suites by Hilton Raleigh Durham Airport Brier Creek

Embassy Suites by Hilton Raleigh Durham Airport Brier Creek
18.2 km from Duke Regional Hospital
United States
Darren C.
CA $227
CA $257 total
includes taxes & fees
Oct 18 - Oct 19
Embassy Suites by Hilton Raleigh Durham Airport Brier Creek
A modern hotel with a prominent entrance, multiple floors, and a balcony on the second floor.
A modern hotel room with a bed, a desk, a chair, a small seating area, and a kitchenette.
A modern dining area with wooden tables and chairs, large windows, and geometric pendant lighting.
A modern hotel lobby with a reception desk, a beverage refrigerator, and a well-stocked snack bar.

14. SpringHill Suites by Marriott Durham City View

SpringHill Suites by Marriott Durham City View
5.4 km from Duke Regional Hospital
United States
Taurean
CA $183
CA $208 total
includes taxes & fees
Nov 1 - Nov 2
SpringHill Suites by Marriott Durham City View
A lobby with a green sofa, yellow chairs, a coffee table with drinks, and a window with plants.
An indoor swimming pool with clear glass walls, a tiled floor, and a seating area with chairs and a table.
A bar area with a granite countertop, wooden chairs, and a large television screen.
A business center with wooden paneling, multiple workstations, and framed artwork on the walls.

15. Hilton Garden Inn Durham/University Medical Center

Hilton Garden Inn Durham/University Medical Center
9th Street District, 4 km from Duke Regional Hospital
United States
Hal
CA $197
CA $224 total
includes taxes & fees
Nov 2 - Nov 3
Hilton Garden Inn Durham/University Medical Center
Restaurant
A reception area with two wooden reception desks, a potted plant, and a computer on the wall.
An indoor swimming pool with clear water, a lifeguard chair, and a sign indicating no diving.
A hotel room with two beds, a desk, a chair, a TV, and a bathroom.

16. Courtyard Raleigh-Durham Airport/Brier Creek

Courtyard Raleigh-Durham Airport/Brier Creek
16.6 km from Duke Regional Hospital
United States
eidy
CA $191
CA $216 total
includes taxes & fees
Oct 18 - Oct 19
Courtyard Raleigh-Durham Airport/Brier Creek
An outdoor patio with wicker furniture, a stone fire pit, and a brick building in the background.
A gym with treadmills, elliptical machines, a bench press, and a blue balance board.
A multi-story brick building with a modern entrance and a parking lot.
A spacious lobby with a reception desk, seating area, and a beverage kiosk.

17. Residence Inn Durham McPherson/Duke University Medical Cntr

Residence Inn Durham McPherson/Duke University Medical Cntr
Trinity Park, 4.1 km from Duke Regional Hospital
United States
Patricia
CA $224
CA $255 total
includes taxes & fees
Nov 1 - Nov 2
Residence Inn Durham McPherson/Duke University Medical Cntr
Exterior
A spacious lobby with a reception desk, a central seating area with a round table and chairs, and a staircase leading to an upper level.
A modern interior with a kitchen area, dining space, and seating.
A covered outdoor area with a symmetrical design, featuring a central seating area with chairs and a table, flanked by columns and potted plants.

18. Homewood Suites by Hilton Raleigh-Durham AP/Research Triangle

Homewood Suites by Hilton Raleigh-Durham AP/Research Triangle
17.3 km from Duke Regional Hospital
United States
Andrew
CA $157
CA $178 total
includes taxes & fees
Oct 11 - Oct 12
Homewood Suites by Hilton Raleigh-Durham AP/Research Triangle
A hotel dining area with round tables, chairs, and floral centerpieces.
A modern restaurant with wooden accents, multiple seating areas, and a bar in the background.
A modern living room with a sofa, ottoman, coffee table, and a fireplace.
A well-lit store with shelves stocked with snacks, beverages, and bottled water.

19. Marriott Raleigh Durham Research Triangle Park

Marriott Raleigh Durham Research Triangle Park
16.6 km from Duke Regional Hospital
United States
Chase
CA $191
CA $217 total
includes taxes & fees
Nov 1 - Nov 2
Marriott Raleigh Durham Research Triangle Park
An outdoor cafe with tables and chairs, umbrellas, and a bicycle parked nearby.
A spacious lobby with a curved ceiling, large windows, and a variety of seating arrangements including sofas, tables, and chairs.
A modern building with a curved facade and a flat roof.
A spacious hotel lobby with a curved seating area, large windows, and modern lighting fixtures.

20. The Durham Hotel

The Durham Hotel
Downtown Durham, 4.5 km from Duke Regional Hospital
United States
Connie
CA $265
CA $301 total
includes taxes & fees
Oct 20 - Oct 21
The Durham Hotel
View all properties

Compare popular hotels close to Duke Regional Hospital

Property
Star rating
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A breakfast area with a chalkboard menu, a sign indicating breakfast starts here, and a variety of food items like waffles, oatmeal, and fruits.
Hampton Inn & Suites Durham/North I-85
9.0
Wonderful
1,003 reviews
View
A hotel room with two beds, a flat-screen TV, a wooden headboard, and a carpeted floor.
Holiday Inn Express Durham by IHG
8.8
Excellent
1,003 reviews
View
A hotel room with a television on a wooden cabinet, a desk with a chair, and a lamp.
Red Roof Inn Durham - Duke Univ Medical Center
6.8
1,002 reviews
View
A stone fire pit surrounded by striped chairs and tables in an outdoor lounge area with a view of a building in the background.
Hampton Inn & Suites Durham University Medical Center
9.6
Exceptional
566 reviews
View
An outdoor patio area with round tables and chairs, large umbrellas, and a glass door entrance.
Fairfield by Marriott Inn & Suites Durham
9.6
Exceptional
55 reviews
View

Top Duke Regional Hospital Hotel Reviews

Hampton Inn & Suites Durham/North I-85

Hampton Inn & Suites Durham/North I-85

10/10 Excellent
"Clean rooms and friendly staff"
Darrel 5-night trip
Posted 4 hours ago
Hampton Inn & Suites Durham/North I-85
Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit

10/10 Excellent
"The house was absolutely immaculate and Kristin could not have nicer or more helpful. The location was just 25 minutes from RDU, 12 minutes from downtown Durham and about a half an hour from Chapel Hill. Comfortable living room for my small group, large screen TV with all the streaming channels and a very cool coffee grinder/maker for regular or espresso coffee. Highly recommend. John L"
John L. 3-night trip
Posted 10 hours ago
Curated & Caffeinated! Gem near Duke & Downtown • Espresso bar, Eco+, Fire Pit
Holiday Inn Express Durham by IHG

Holiday Inn Express Durham by IHG

8/10 Good
"Close to the highway so you can hear the trucks and motorcycles."
Dorothy 2-night trip
Posted 11 hours ago
Holiday Inn Express Durham by IHG
Comfort Inn & Suites Durham near Duke University

Comfort Inn & Suites Durham near Duke University

8/10 Good
"Unsure"
Edwin L 1-night trip
Posted 1 day ago
Comfort Inn & Suites Durham near Duke University
Unscripted Durham, Part of JDV by Hyatt

Unscripted Durham, Part of JDV by Hyatt

10/10 Excellent
"Convenient"
Robert 1-night trip
Posted 1 day ago
Unscripted Durham, Part of JDV by Hyatt
University Inn Durham next to Duke University Medical Center

University Inn Durham next to Duke University Medical Center

10/10 Excellent
"Very clean and large room. Convenient to Duke campus."
Arthur 2-night trip
Posted 1 day ago
University Inn Durham next to Duke University Medical Center
Millennium Hotel Durham

Millennium Hotel Durham

10/10 Excellent
"Good"
Zhihua 1-night trip
Posted 2 days ago
Millennium Hotel Durham
The Durham Hotel

The Durham Hotel

10/10 Excellent
"One of the best hotels I have ever been to.. period world wide. Nice rooms, modern era decor, great in house restaurant with superb breakfast at reasonable price and coffee bar. Best cortado I ever had. All staff were friendly and super supportive. Parking in lots street or garage within easy walking distance. Many restaurants and bars in the area. Reasonably safe area but there are panhandlers on occasion. Room had adequate closet space, excellent bathroom and shower. Quiet at night. Super comfy bed. I’m a coffee nerd and they offer fresh ground gourmet options brought to your door each morning if you choose the night before. No hotel I’ve ever stayed at offered this. I liked it so much I returned on a return visit to the city. No pool but workout facility. Highly recommended if you travel in the area.,"
Eugene 1-night trip
Posted 2 days ago
The Durham Hotel
The Lodge at Duke Medical Center

The Lodge at Duke Medical Center

10/10 Excellent
"My stay was great!"
Kenneth 1-night trip
Posted 7 days ago
The Lodge at Duke Medical Center

Frequently asked questions

What's the area like around Duke Regional Hospital?
Duke Regional Hospital is located in an area of Durham known for its stunning cathedral. If you're looking for a convenient place to stay, check out the 10 hotels and other accommodations you'll find within a mile.
Where is the best place to stay close to Duke Regional Hospital?
Courtyard Durham Near Duke University/Downtown is one of the top choices for your stay based on our traveler data, and this hotel offers a restaurant and free parking. It's located 2.2 mi (3.5 km) from Duke Regional Hospital. Other good choices within a few miles include Holiday Inn Express Durham by IHG and Red Roof Inn Durham - Duke Univ Medical Center.
How many hotels can I expect to find near Duke Regional Hospital?
Expedia has 10 hotels and other accommodations within a mile from Duke Regional Hospital.
If I need to cancel the hotel reservation for my stay near Duke Regional Hospital, will I receive a refund?
Yes! Most hotel room reservations are fully refundable provided that you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a non-refundable reservation, you might be able to cancel it and be given a refund within 24 hours of booking. Add dates, click "Search", then you can filter by "fully refundable" to get the best deals near Duke Regional Hospital.
What can I see and do near Duke Regional Hospital?
You might want to spend some time browsing the exhibits at Museum of Life and Science, Nasher Museum of Art at Duke University, or Bennett Place. While you're exploring, swing by American Tobacco Campus, Cameron Indoor Stadium, and Wallace Wade Stadium to learn a bit about the area. You can enjoy live performances at Carolina Theatre and Common Ground Theatre.

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