A lush green field with tall grasses and pink wildflowers, surrounded by dense trees.

Pike County Vacation Rentals

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Our top choices for Pike County vacation rentals

A wooden deck with a railing, surrounded by trees with autumn foliage.

1. 3-bedroom country home in Pike Co Il with AC and heat

3-bedroom country home in Pike Co Il with AC and heat
Chambersburg
9.6 out of 10, Exceptional, (4 reviews)
"Property had all the amenities needed for a comfortable stay. Very private, quiet setting perfect for a relaxed stay."
United States
Chad L.
The price is CA $160
CA $277 total
includes taxes & fees
Oct 4 - Oct 5
3-bedroom country home in Pike Co Il with AC and heat
A hotel room with a large bed, two bedside lamps, a modern bathroom, and a vibrant abstract painting on the wall.

2. Lighthouse Inn & Suites

Lighthouse Inn & Suites
4.0 star property
Hannibal
8.8 out of 10, Excellent, (47 reviews)
"Wonderful place to stay!"
United States
Kari
The price is CA $227
CA $311 total
includes taxes & fees
Oct 4 - Oct 5
Lighthouse Inn & Suites
A natural outdoor setting with a stone fire pit surrounded by wooden benches and a wooden bridge.

3. Your home away from home in the Country

Your home away from home in the Country
Coatsburg
9.8 out of 10, Exceptional, (46 reviews)
"We will make your place a regular stay when in town to visit my son and wife!"
United States
Kimberly G.
The price is CA $186
CA $227 total
includes taxes & fees
Oct 7 - Oct 8
Your home away from home in the Country
A two-story house with a wooden deck and a garden with colorful flowers.

4. COUNTRY HOME WITH LLAMAS JUST OUTSIDE THE WINDOWS!

COUNTRY HOME WITH LLAMAS JUST OUTSIDE THE WINDOWS!
Bluffs
10.0 out of 10, Exceptional, (64 reviews)
"Very nice property"
United States
Brian G.
The price is CA $283
CA $338 total
includes taxes & fees
Oct 18 - Oct 19
COUNTRY HOME WITH LLAMAS JUST OUTSIDE THE WINDOWS!
A dining area with a wooden table and chairs, a patterned rug, and a kitchen in the background.

5. Bunkhouse Seventy-Four - Cute, quaint and just minutes from Jacksonville, IL

Bunkhouse Seventy-Four - Cute, quaint and just minutes from Jacksonville, IL
Jacksonville
10.0 out of 10, Exceptional, (27 reviews)
"Really enjoyed our stay. The place was very clean and bed really comfortable "
United States
David W.
The price is CA $141
CA $179 total
includes taxes & fees
Oct 4 - Oct 5
Bunkhouse Seventy-Four - Cute, quaint and just minutes from Jacksonville, IL
A modern kitchen with white cabinets, a stainless steel refrigerator, and a dining area with a wooden table and white chairs.

6. Peaceful, Country Cottage with Open Floor Plan

Peaceful, Country Cottage with Open Floor Plan
Quincy
9.8 out of 10, Exceptional, (224 reviews)
"Only there for a one night stay, but very beautiful and comfortable!"
United States
Vicki W.
The price is CA $185
CA $351 total
includes taxes & fees
Oct 4 - Oct 5
Peaceful, Country Cottage with Open Floor Plan
A room with a brick wall, shelves with plants, a framed painting, and a patterned bench.

7. Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
Hannibal
9.8 out of 10, Exceptional, (67 reviews)
"Great location for downtown exploring."
United States
Lisa B.
The price is CA $159
CA $265 total
includes taxes & fees
Nov 2 - Nov 3
Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
A living room with a black leather sofa, a wooden coffee table, and a television mounted on the wall.

8. Newly Remodeled Town House!

Newly Remodeled Town House!
Mount Sterling
9.6 out of 10, Exceptional, (15 reviews)
"Good location, nicely furnished."
United States
Scott S.
The price is CA $154
CA $311 total
includes taxes & fees
Oct 12 - Oct 13
Newly Remodeled Town House!
A cozy living room with a wooden staircase, a chessboard on a round table, and a lamp on a side table.

9. The John Sydney House - Family and Pet Friendly Historic Home Downtown

The John Sydney House - Family and Pet Friendly Historic Home Downtown
Hannibal
9.8 out of 10, Exceptional, (24 reviews)
"Rooms were clean and the decor was very well done! We loved our stay here and the hosts were responsive to all our needs."
United States
Brian H.
The price is CA $240
CA $367 total
includes taxes & fees
Oct 5 - Oct 6
The John Sydney House - Family and Pet Friendly Historic Home Downtown
A spacious room with hardwood flooring, a grand piano, a comfortable armchair, and a chandelier.

10. The Yellow Rose Historic Home

The Yellow Rose Historic Home
Louisiana
9.8 out of 10, Exceptional, (19 reviews)
"Everything was great!"
United States
Brendan R.
The price is CA $352
CA $519 total
includes taxes & fees
Oct 4 - Oct 5
The Yellow Rose Historic Home
A bedroom with a wooden headboard, a large bed with white bedding, a bench, and a dresser with a mirror.

11. The Farmhouse Loft "Greene County's Guesthouse"

The Farmhouse Loft "Greene County's Guesthouse"
Carrollton
9.8 out of 10, Exceptional, (63 reviews)
"Stayed at the Farmhouse Loft for a local wedding. It met all our expectations. Great location on the town square. Will definitely stay there again "
United States
Gregory D.
The price is CA $121
CA $234 total
includes taxes & fees
Oct 12 - Oct 13
The Farmhouse Loft "Greene County's Guesthouse"
A building with a glass door marked "108" and a sign for "Web Print Radio Television Public Relations."

12. The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.

The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.
Hannibal
9.8 out of 10, Exceptional, (17 reviews)
"We had a great stay here. It was much larger than expected with a sitting room, bedroom, bath, kitchen and laundry area. In the heart of all in town and yet very safe."
United States
Dan R.
The price is CA $149
CA $192 total
includes taxes & fees
Oct 26 - Oct 27
The Library, 1-queen bed, 1-bedroom apartment in Hannibal awaits your visit.
A modern kitchen with white cabinets, stainless steel appliances, and a wooden floor.

13. Spacious & Modern 2BR Home with Attached Garage

Spacious & Modern 2BR Home with Attached Garage
Quincy
10.0 out of 10, Exceptional, (52 reviews)
"Nicely decorated and very comfortable."
United States
Marsha
The price is CA $155
CA $318 total
includes taxes & fees
Oct 19 - Oct 20
Spacious & Modern 2BR Home with Attached Garage
A rooftop terrace with a brick wall, a metal railing, and a table with chairs.

14. Deck + River View: Loft in Downtown Hannibal

Deck + River View: Loft in Downtown Hannibal
3.0 star property
Hannibal
The price is CA $196
CA $377 total
includes taxes & fees
Oct 4 - Oct 5
Deck + River View: Loft in Downtown Hannibal
A modern kitchen with stainless steel appliances, a stone accent wall, and a bar area.

15. Aunt Lele's Cozy Cottage

Aunt Lele's Cozy Cottage
Quincy
9.8 out of 10, Exceptional, (46 reviews)
"Perfect place for our family of 5 to enjoy a weekend visiting my wife’s family."
United States
Matt B.
The price is CA $96
CA $223 total
includes taxes & fees
Oct 11 - Oct 12
Aunt Lele's Cozy Cottage
A modern house with a stone facade, a dark garage door, and a well-lit entrance.

16. Cool 2-bedroom three bed contemporary condo in a quiet area of Quincy.

Cool 2-bedroom three bed contemporary condo in a quiet area of Quincy.
Quincy
10.0 out of 10, Exceptional, (7 reviews)
"Very nice and clean place"
United States
G K.
The price is CA $211
CA $373 total
includes taxes & fees
Oct 8 - Oct 9
Cool 2-bedroom three bed contemporary condo in a quiet area of Quincy.
A living room with a grey sofa, a white coffee table, and teal chairs. A kitchen is visible through an open door.

17. Modern and comfy home five minutes from downtown

Modern and comfy home five minutes from downtown
Hannibal
10.0 out of 10, Exceptional, (21 reviews)
"House was perfect for our stay."
United States
Brent W.
The price is CA $130
CA $414 total
includes taxes & fees
Oct 7 - Oct 8
Modern and comfy home five minutes from downtown
A dining area with a wooden table and chairs, a chandelier, and a red sofa in the background.

18. Vibey home a few blocks from downtown Hannibal

Vibey home a few blocks from downtown Hannibal
Hannibal
9.8 out of 10, Exceptional, (15 reviews)
"Very Nice house!!! Enjoyed my stay there."
United States
Shaun P.
The price is CA $121
CA $402 total
includes taxes & fees
Oct 6 - Oct 7
Vibey home a few blocks from downtown Hannibal
A rustic log cabin with a porch and a chimney.

19. Audrey's Abode - Restored log cabin, country setting, minutes from Jacksonville

Audrey's Abode - Restored log cabin, country setting, minutes from Jacksonville
Jacksonville
10.0 out of 10, Exceptional, (17 reviews)
"The place was really neat and the host was incredibly friendly"
United States
Dylan
The price is CA $183
CA $225 total
includes taxes & fees
Oct 4 - Oct 5
Audrey's Abode - Restored log cabin, country setting, minutes from Jacksonville
A bedroom with a bed, a desk, a chair, a TV, and a window.

20. Updated efficiency unit attached to the Parlor on Paris - Rent both and save

Updated efficiency unit attached to the Parlor on Paris - Rent both and save
Hannibal
9.6 out of 10, Exceptional, (5 reviews)
"Great for a weekend get away."
United States
Jordon S.
The price is CA $71
CA $278 total
includes taxes & fees
Oct 4 - Oct 5
Updated efficiency unit attached to the Parlor on Paris - Rent both and save
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Pike County Hotel Reviews

Best Western On The River

Best Western On The River

8/10 Good
"Within walking distance of downtown."
Gilda 3-night trip
Posted 12 hours ago
Best Western On The River

Find out more about Pike County

Everything you need to know about Pike County vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Pike County vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Pike County vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search. 

Pike County vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Pike County. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depends on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Pike County vacation rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a vacation rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Pike County vacation rentals we have selected for you start as low as CA $179 per night. Entering your travel dates in the search wizard you might find even better deals!

How to find incredible deals on Pike County rentals

At Expedia, we put the best Pike County vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Pike County rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Pike County vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Pike County. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.