Title: Los Santos LGBT Friendly Hotels : Book the Right LGBT Friendly Hotels Room in Los Santos, Panama - Expedia.ca [Los Santos Hotels](https://expedia.ca/Destinations-In-Los-Santos.d6246240.Hotel-Destinations)[Vacation Rentals in Los Santos](https://expedia.ca/Destinations-In-Los-Santos.d6246240.Vacation-Rental-Destinations)[Los Santos Flights](https://expedia.ca/Destinations-In-Los-Santos.d6246240.Flight-Destinations)[Los Santos Car Rentals](https://expedia.ca/Destinations-In-Los-Santos.d6246240.Car-Rental-Destinations)[Los Santos Vacations](https://expedia.ca/Los-Santos.d6246240.Destination-Travel-Guides) ![View at Venao beach in Azuero peninsula, Panama.](https://images.trvl-media.com/place/6336814/792c4e82-5e8a-4f1d-b9a6-3ef041d48b83.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6336814/792c4e82-5e8a-4f1d-b9a6-3ef041d48b83.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Top Cities in Los Santos ![Punta Cana ](https://images.trvl-media.com/place/553248623859250109/fd47f4af-cda5-4066-8af8-a2911d33d914.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Canas [](https://expedia.ca/Canas-Hotels-LGBT-Friendly-Hotel.0-0-d553248623859250109-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) ![Los Santos, Panama](https://images.trvl-media.com/place/3000450432/c8f2d7a3-e530-458c-a204-93b2d90d7f2a.jpg?impolicy=fcrop&w=384&h=216&q=medium) #### Tonosi [](https://expedia.ca/Tonosi-Hotels-LGBT-Friendly-Hotel.0-0-d3000450432-tLGBTFriendlyHotel.Travel-Guide-Filter-Hotels) ## Check availability on Los Santos LGBT Friendly Hotels Tonight [Feb 10 - Feb 11](https://www.expedia.ca/Hotel-Search?regionId=6246240&startDate=2026-02-10&endDate=2026-02-11&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) Tomorrow [Feb 11 - Feb 12](https://www.expedia.ca/Hotel-Search?regionId=6246240&startDate=2026-02-11&endDate=2026-02-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) This weekend [Feb 13 - Feb 15](https://www.expedia.ca/Hotel-Search?regionId=6246240&startDate=2026-02-13&endDate=2026-02-15&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) Next weekend [Feb 20 - Feb 22](https://www.expedia.ca/Hotel-Search?regionId=6246240&startDate=2026-02-20&endDate=2026-02-22&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=lgbtq_welcoming) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Los-Santos-LGBT-Friendly-Hotel.0-0-d6246240-tLGBTFriendlyHotel.Hotel-Filter-Destinations)[ Sign up, it's free ](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FDestinations-In-Los-Santos-LGBT-Friendly-Hotel.0-0-d6246240-tLGBTFriendlyHotel.Hotel-Filter-Destinations) ## Top Los Santos Hotel Reviews ![Hotel Presidente](https://images.trvl-media.com/lodging/16000000/15620000/15615000/15614946/8b2929d2_y.jpg) ### Hotel Presidente 10/10 Excellent "We return year after year" [](https://expedia.ca/Las-Tablas-Hotels-Hotel-Presidente.h15614946.Hotel-Information) ![Hotel Riu Playa Blanca - All Inclusive](https://images.trvl-media.com/lodging/8000000/7330000/7326200/7326126/60f3aac3_y.jpg) ### Hotel Riu Playa Blanca - All Inclusive 10/10 Excellent "Execellen choise for vacations" [](https://expedia.ca/Rio-Hato-Hotels-Riu-Playa-Blanca-All-Inclusive.h7326126.Hotel-Information) ![Casa Loma](https://images.trvl-media.com/lodging/12000000/11930000/11928100/11928041/51c88457_y.jpg) ### Casa Loma 10/10 Excellent "Room was great! Clean, good location for exploring Pedasi! Family friendly Good breakfast and coffee! " [](https://expedia.ca/Pedasi-Hotels-Casa-Loma.h11928041.Hotel-Information) ![Pedasi Sport Club](https://images.trvl-media.com/lodging/12000000/11930000/11927600/11927532/0597cf89_y.jpg) ### Pedasi Sport Club 10/10 Excellent "Pool was clean and nice temperature. There were 2 barking dogs on the property- looked like strays. A bit annoying but the room and grounds were nice." [](https://expedia.ca/Pedasi-Hotels-Pedasi-Sport-Club.h11927532.Hotel-Information) ![Selina Playa Venao - Hostel](https://images.trvl-media.com/lodging/9000000/8310000/8307900/8307824/7b5eed1b_y.jpg) ### Selina Playa Venao - Hostel 8/10 Good "The DJ and dance party was great. The main facility was nice - attractive, cool vibe, nice beach, beach shower, nice pool, nice lounge chairs... room / beds were great.. looked great... but the shower curtain was really gross - dirty and moldy and made you feel like you were in a cheap filthy place, even though everything else was good... strange that such an easy and cheap fix would be left in such a disgusting state. Staff were great and altogether a nice stay. Thanks" [](https://expedia.ca/Las-Escobas-Del-Venado-Hotels-Selina-Playa-Venao.h8307824.Hotel-Information) ![Hotel Posada Destiladeros](https://images.trvl-media.com/lodging/12000000/11840000/11838000/11837980/f43de052_y.jpg) ### Hotel Posada Destiladeros 10/10 Excellent "La Posada está ubicada en una propiedad simplemente hermosa, la construcción tiene un diseño de madera de lujo. Las cabañas están en medio de la selva y prácticamente desde cualquier esquina se puede ver el mar, y tiene acceso directo a la playa, una playa extensa perfecta para caminar o bañarse. El área de piscina es muy bonita. Pase dos noches en el paraíso, vimos pajaritos de colores de toda clase, aguiluchos y una iguana. Este lugar es perfecto si lo que buscas es paz, naturaleza y tranquilidad. El desayuno incluido es delicioso, incluso nos dieron agua de pipa cada mañana. El servicio al cliente el primer día de check in estuvo un poco lento, sin embargo se notaba que son un equipo pequeño al frente de la administración. Todos fueron siempre muy atentos y amables. ¡Gracias!! Regresaré." [](https://expedia.ca/Punta-Mala-Hotels-Hotel-Posada-Destiladeros.h11837980.Hotel-Information) ![Casa Lajagua](https://images.trvl-media.com/lodging/21000000/20160000/20153900/20153817/d30dea54_y.jpg) ### Casa Lajagua 10/10 Excellent "April and staff have built up a wonderful rustic location with a lovely and peaceful atmosphere but close enough to town by foot. The Al Fresco breakfast was lovely especially the homemade chocolate cake! April was very attentive as i was a bit under the weather but she helped me out. " [](https://expedia.ca/Pedasi-Hotels-Casa-Lajagua.h20153817.Hotel-Information) ![Hotel El Sitio Playa Venao](https://images.trvl-media.com/lodging/9000000/8740000/8731000/8730917/6969e9f7_y.jpg) ### Hotel El Sitio Playa Venao 10/10 Excellent "The hotel was just perfect. The location is incredible. The staff is extremely nice and polite, super friendly and ready to help you. The room looks exactly like the pictures and it was spotless. The food at the restaurant is excellent. I could not have chosen a better place. Will come back." [](https://expedia.ca/Las-Escobas-Del-Venado-Hotels-Hotel-El-Sitio-Playa-Venao.h8730917.Hotel-Information) ![Selina River Venao](https://images.trvl-media.com/lodging/74000000/73420000/73412000/73411943/fe355382_y.jpg) ### Selina River Venao 10/10 Excellent "Clean, lovely place. Felt like being in the jungle while next to the beach. People here were friendly." 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