Title: Book the Best BUSINESS Hotels in Des Moines in 2026 | Expedia.ca [Des Moines Travel Guide](https://expedia.ca/Des-Moines.dx601690)[Hotels in Des Moines](https://expedia.ca/Des-Moines-Hotels.d601690.Travel-Guide-Hotels)[Vacation Rentals in Des Moines](https://expedia.ca/Des-Moines-Vacation-Rentals.d601690.Travel-Guide-VacationRentals)[Flights to Des Moines](https://expedia.ca/Cheap-Flights-To-Des-Moines.d601690.Travel-Guide-Flights)[Things to do in Des Moines](https://expedia.ca/Things-To-Do-In-Des-Moines.d601690.Travel-Guide-Activities)[Des Moines Car Rentals](https://expedia.ca/Car-Rentals-In-Des-Moines.d601690.Car-Rental-Guide)[Des Moines Vacation Packages](https://expedia.ca/Des-Moines.d601690.Destination-Travel-Guides) ![Iowa State Capitol](https://images.trvl-media.com/place/601690/d6e0e2f2-7876-4d18-865a-ae2f68f4627c.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Business Hotels in Des Moines, IA - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Des Moines Business Hotels Tonight [Dec 17 - Dec 18](https://www.expedia.ca/Hotel-Search?regionId=601690&startDate=2025-12-17&endDate=2025-12-18&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Tomorrow [Dec 18 - Dec 19](https://www.expedia.ca/Hotel-Search?regionId=601690&startDate=2025-12-18&endDate=2025-12-19&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) This weekend [Dec 19 - Dec 21](https://www.expedia.ca/Hotel-Search?regionId=601690&startDate=2025-12-19&endDate=2025-12-21&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) Next weekend [Dec 26 - Dec 28](https://www.expedia.ca/Hotel-Search?regionId=601690&startDate=2025-12-26&endDate=2025-12-28&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true&travelerType=business_friendly) ## Our top choices for Des Moines business-friendly hotels ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/53b90d46.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily on-the-go breakfast](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/b31ca2c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/7f9d044a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Egyptian cotton sheets, premium bedding, in-room safe, desk](https://images.trvl-media.com/lodging/13000000/12760000/12756300/12756236/7621407d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Holiday Inn Express & Suites Des Moines Downtown by IHG [](https://www.expedia.ca/Des-Moines-Hotels-Holiday-Inn-Express-Suites-Des-Moines-Downtown.h12756236.Hotel-Information) Downtown Des Moines 9.2/10 Wonderful (970) "Wonderful stay as always!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brenda CA $122 CA $137 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Des-Moines-Hotels-Holiday-Inn-Express-Suites-Des-Moines-Downtown.h12756236.Hotel-Information) ![Standard Room, 1 King Bed | Jetted tub](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/6aa3a071.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Suite, 1 Queen Bed | Jetted tub](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/4622c857.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/a95f1765.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fitness facility](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/f005535b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Days Inn & Suites by Wyndham Des Moines Airport [](https://www.expedia.ca/Des-Moines-Hotels-Days-Inn-Suites-By-Wyndham-Des-Moines-Airport.h49826.Hotel-Information) Greater South Side 8.6/10 Excellent (1684) "Had a great stay and was impressed with the staff and the hotel. Will stay again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kevin CA $87 CA $97 total includes taxes & fees Dec 24 - Dec 25 [](https://www.expedia.ca/Des-Moines-Hotels-Days-Inn-Suites-By-Wyndham-Des-Moines-Airport.h49826.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/77600/77590/01d93670.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/80000/77600/77590/4a8285f4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/80000/77600/77590/09fcb0cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Property amenity](https://images.trvl-media.com/lodging/1000000/80000/77600/77590/25aa74bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Fairfield Inn and Suites by Marriott Des Moines West [](https://www.expedia.ca/Des-Moines-Hotels-Fairfield-Inn-And-Suites-By-Marriott-Des-Moines-West.h77590.Hotel-Information) West Des Moines 9.0/10 Wonderful (1004) "Room was clean, staff was courteous and the bed was comfortable. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Craig CA $120 CA $135 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Des-Moines-Hotels-Fairfield-Inn-And-Suites-By-Marriott-Des-Moines-West.h77590.Hotel-Information) ![Indoor pool, outdoor pool](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836184/a1ae2959.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836184/7aea1f22.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836184/5f933aab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836184/4f9f1eae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Drury Inn & Suites West Des Moines [](https://www.expedia.ca/Des-Moines-Hotels-Drury-Inn-Suites-West-Des-Moines.h1836184.Hotel-Information) West Des Moines 9.4/10 Exceptional (1000) "The location was great." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Sherri CA $138 CA $154 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Des-Moines-Hotels-Drury-Inn-Suites-West-Des-Moines.h1836184.Hotel-Information) ![Reception](https://images.trvl-media.com/lodging/1000000/50000/42600/42540/157a0ec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/50000/42600/42540/c5be7d60.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe, One King Bed, Non-Smoking](https://images.trvl-media.com/lodging/1000000/50000/42600/42540/6e31869a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/1000000/50000/42600/42540/39319c4c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Hampton Inn West Des Moines Lake Drive [](https://www.expedia.ca/Des-Moines-Hotels-Hampton-Inn-West-Des-Moines-Lake-Drive.h42540.Hotel-Information) West Des Moines 9.0/10 Wonderful (1002) "Will stay there again " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Marc CA $112 CA $125 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Des-Moines-Hotels-Hampton-Inn-West-Des-Moines-Lake-Drive.h42540.Hotel-Information) ![Property amenity](https://images.trvl-media.com/lodging/1000000/60000/50200/50111/e35bf7c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/60000/50200/50111/7dd58f5f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Premium bedding, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/60000/50200/50111/0e2232c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily buffet breakfast](https://images.trvl-media.com/lodging/1000000/60000/50200/50111/57391447.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### La Quinta Inn & Suites by Wyndham Des Moines West Clive [](https://www.expedia.ca/Des-Moines-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Des-Moines-West-Clive.h50111.Hotel-Information) Clive 8.6/10 Excellent (1004) "Great place to stay! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kirsten CA $90 CA $101 total includes taxes & fees Jan 4 - Jan 5, 2026 [](https://www.expedia.ca/Des-Moines-Hotels-La-Quinta-Inn-Suites-By-Wyndham-Des-Moines-West-Clive.h50111.Hotel-Information) ![Indoor pool, outdoor pool, sun loungers](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152222/43001d37.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Superior Suite, 1 King Bed with Sofa bed, Hot Tub](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152222/bde3afda.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior entrance](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152222/a319fe56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/2000000/1160000/1152300/1152222/e7c93771.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Stoney Creek Hotel Des Moines - Johnston [](https://www.expedia.ca/Des-Moines-Hotels-Stoney-Creek-Hotel-Des-Moines-Johnston.h1152222.Hotel-Information) Johnston 8.8/10 Excellent (1790) "The breakfast and coffee was absolutely amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Brenda CA $112 CA $125 total includes taxes & fees Dec 22 - Dec 23 [](https://www.expedia.ca/Des-Moines-Hotels-Stoney-Creek-Hotel-Des-Moines-Johnston.h1152222.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/10000/9700/9664/e0eedf1f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool, sun loungers](https://images.trvl-media.com/lodging/1000000/10000/9700/9664/e64ec889.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/9700/9664/62e9f148.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Desk, iron/ironing board, rollaway beds, free WiFi](https://images.trvl-media.com/lodging/1000000/10000/9700/9664/29d8e39f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn & Suites Des Moines - Merle Hay Road [](https://www.expedia.ca/Des-Moines-Hotels-Quality-Inn-Suites.h9664.Hotel-Information) Lovington 7.6/10 Good (1011) "A nice service and countroble stay!!!!!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Richar CA $76 CA $85 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Des-Moines-Hotels-Quality-Inn-Suites.h9664.Hotel-Information) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/100000/99800/99780/563c32d8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/100000/99800/99780/9ba43e4e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/100000/99800/99780/4bd3b9c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/100000/99800/99780/e02ac4f1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Country Inn & Suites by Radisson, Des Moines West, IA [](https://www.expedia.ca/Des-Moines-Hotels-Country-Inn-Suites-By-Radisson.h99780.Hotel-Information) Clive 8.8/10 Excellent (1005) "Was a great stay and great price. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Roger CA $110 CA $123 total includes taxes & fees Dec 25 - Dec 26 [](https://www.expedia.ca/Des-Moines-Hotels-Country-Inn-Suites-By-Radisson.h99780.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/480000/473200/473122/35b2ee27.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free daily continental breakfast](https://images.trvl-media.com/lodging/1000000/480000/473200/473122/a6b7d6ee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Pool](https://images.trvl-media.com/lodging/1000000/480000/473200/473122/372c3679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby](https://images.trvl-media.com/lodging/1000000/480000/473200/473122/3b0888ae.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Baymont by Wyndham Des Moines Airport [](https://www.expedia.ca/Des-Moines-Hotels-Baymont-By-Wyndham-Des-Moines-Airport.h473122.Hotel-Information) Southwestern Hills 9.4/10 Exceptional (1162) "Great breakfast for the price point. Hotel front desk is very professional and Manager is very responsive and customer service focused. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Rob CA $110 CA $123 total includes taxes & fees Dec 19 - Dec 20 [](https://www.expedia.ca/Des-Moines-Hotels-Baymont-By-Wyndham-Des-Moines-Airport.h473122.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2026-01-01&endDate=2026-01-02®ionId=601690&adults=2&travelerType=business_friendly&sort=RECOMMENDED&openPlayBack=true) ## Top Des Moines Hotel Reviews ![Hyatt Place West Des Moines Jordan Creek](https://images.trvl-media.com/lodging/17000000/16120000/16112600/16112546/f70b7069_y.jpg) ### Hyatt Place West Des Moines Jordan Creek 10/10 Excellent "very clean" [](https://expedia.ca/Des-Moines-Hotels-Hyatt-Place-West-Des-Moines-Jordan-Creek.h16112546.Hotel-Information) ![Quality Inn & Suites Des Moines - Merle Hay Road](https://images.trvl-media.com/lodging/1000000/10000/9700/9664/257ab000_y.jpg) ### Quality Inn & Suites Des Moines - Merle Hay Road 10/10 Excellent "Breakfast was good love their biscuits so soft & moist. The room was nice, clean, and spacious bed was very comfortable." [](https://expedia.ca/Des-Moines-Hotels-Quality-Inn-Suites.h9664.Hotel-Information) ![Drury Inn & Suites West Des Moines](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836184/2af2a76d_y.jpg) ### Drury Inn & Suites West Des Moines 10/10 Excellent "The location was great." [](https://expedia.ca/Des-Moines-Hotels-Drury-Inn-Suites-West-Des-Moines.h1836184.Hotel-Information) ![Motel 6 West Des Moines, IA](https://images.trvl-media.com/lodging/1000000/990000/986100/986072/e3428772_y.jpg) ### Motel 6 West Des Moines, IA 10/10 Excellent "Room clean & nice" [](https://expedia.ca/Des-Moines-Hotels-Motel-6-West-Des-Moines.h986072.Hotel-Information) ![Sonesta Essential Des Moines](https://images.trvl-media.com/lodging/1000000/60000/50800/50789/9b65231b_y.jpg) ### Sonesta Essential Des Moines 10/10 Excellent "Yes" [](https://expedia.ca/Des-Moines-Hotels-Sonesta-Essential-Des-Moines.h50789.Hotel-Information) ![AmericInn by Wyndham Des Moines Airport](https://images.trvl-media.com/lodging/1000000/860000/856000/855969/6f15108b_y.jpg) ### AmericInn by Wyndham Des Moines Airport 10/10 Excellent "Room was clean enough " [](https://expedia.ca/Des-Moines-Hotels-AmericInn-By-Wyndham-Des-Moines-Airport.h855969.Hotel-Information) ![Des Lux Hotel](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/e7f9fb30_y.jpg) ### Des Lux Hotel 10/10 Excellent "Clean hotel; excellent customer service!" [](https://expedia.ca/Des-Moines-Hotels-Des-Lux-Hotel.h9781455.Hotel-Information) ![Days Inn & Suites by Wyndham Des Moines Airport](https://images.trvl-media.com/lodging/1000000/50000/49900/49826/23994ff1_y.jpg) ### Days Inn & Suites by Wyndham Des Moines Airport 10/10 Excellent "This is an older, but well maintained option and it was convenient. Our room was clean. Staff was friendly and helpful. " [](https://expedia.ca/Des-Moines-Hotels-Days-Inn-Suites-By-Wyndham-Des-Moines-Airport.h49826.Hotel-Information) ![Fairfield Inn and Suites by Marriott Des Moines West](https://images.trvl-media.com/lodging/1000000/80000/77600/77590/01d93670_y.jpg) ### Fairfield Inn and Suites by Marriott Des Moines West 10/10 Excellent "Passing through on way to Michigan from Colorado. Convenient location, excellent service, comfortable room, good breakfast. " [](https://expedia.ca/Des-Moines-Hotels-Fairfield-Inn-And-Suites-By-Marriott-Des-Moines-West.h77590.Hotel-Information) ## Frequently asked questions ### How much do business-friendly hotels in Des Moines cost? ### What are the best business-friendly hotels in Des Moines? ### How many business-friendly hotels are there in Des Moines? ### What are the best cheap business-friendly hotels in Des Moines? ### What are the top business-friendly motels in Des Moines? ### Are there any family-friendly hotels in Des Moines that are also business friendly? ### Why book your business-friendly hotel in Des Moines with Expedia? ### How can I find cheap business-friendly hotels in Des Moines? ### What is there to do in Des Moines near my business-friendly hotel? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rental - Other - More ways to book - [Hotels near 801 Grand ](https://www.expedia.ca/801-Grand-Hotels.0-l6075062-0.Travel-Guide-Filter-Hotels) - [Beaverdale Hotels ](https://www.expedia.ca/Beaverdale-Des-Moines-Hotels.0-n553248635976477137-0.Travel-Guide-Filter-Hotels) - 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