Title: Hotels by Motel 6 in Carlisle from CA $80 | Expedia.ca [Carlisle Travel Guide](https://expedia.ca/Carlisle.dx3000436816)[Hotels in Carlisle](https://expedia.ca/Carlisle-Hotels.d3000436816.Travel-Guide-Hotels)[Vacation Rentals in Carlisle](https://expedia.ca/Carlisle-Vacation-Rentals.d3000436816.Travel-Guide-VacationRentals)[Flights to Carlisle](https://expedia.ca/Cheap-Flights-To-Carlisle.d3000436816.Travel-Guide-Flights)[Carlisle Car Rentals](https://expedia.ca/Car-Rentals-In-Carlisle.d3000436816.Car-Rental-Guide)[Carlisle Vacation Packages](https://expedia.ca/Carlisle.d3000436816.Destination-Travel-Guides) ![Default HTG hotel image](https://a.travel-assets.com/travel-assets-manager/fallback-images-brand/bex_lodging_v2.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # Find Hotels by Motel 6 in Carlisle from CA $80 - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__calendar_shield.svg) ### Change your mind Book hotels with free cancellation - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Sign in to save 10% or more on thousands of hotels [Sign in](https://www.expedia.ca/login) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Dec 2 - Dec 3](https://www.expedia.ca/Hotel-Search?regionId=3000436816&startDate=2025-12-02&endDate=2025-12-03&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Dec 3 - Dec 4](https://www.expedia.ca/Hotel-Search?regionId=3000436816&startDate=2025-12-03&endDate=2025-12-04&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Dec 5 - Dec 7](https://www.expedia.ca/Hotel-Search?regionId=3000436816&startDate=2025-12-05&endDate=2025-12-07&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Dec 12 - Dec 14](https://www.expedia.ca/Hotel-Search?regionId=3000436816&startDate=2025-12-12&endDate=2025-12-14&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Top Carlisle Motel 6 Hotels ![Free WiFi, bed sheets](https://images.trvl-media.com/lodging/1000000/990000/986100/986072/e3428772.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/990000/986100/986072/bc676331.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/990000/986100/986072/88a27886.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/1000000/990000/986100/986072/b9a52103.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 West Des Moines, IA West Des Moines 7.8/10 Good (696) "Very clean friendly staff " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Isaiah CA $71 CA $80 total includes taxes & fees Dec 21 - Dec 22 [](https://www.expedia.ca/Des-Moines-Hotels-Motel-6-West-Des-Moines.h986072.Hotel-Information) ![Free WiFi](https://images.trvl-media.com/lodging/2000000/1040000/1037800/1037758/ded9ef56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/2000000/1040000/1037800/1037758/f5924cee.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Point of interest](https://images.trvl-media.com/lodging/2000000/1040000/1037800/1037758/c04eda7d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Coffee service](https://images.trvl-media.com/lodging/2000000/1040000/1037800/1037758/e313c142.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Des Moines, IA - North Marquisville 5.8/10 (264) "It is a nice hotel right off the interstate and easy to get in and out of. Staff was very nice and the room was just what I needed for my stay/" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Chris CA $80 CA $90 total includes taxes & fees Jan 1 - Jan 2, 2026 [](https://www.expedia.ca/Des-Moines-Hotels-Motel-6-Des-Moines.h1037758.Hotel-Information) ![Exterior](https://images.trvl-media.com/lodging/1000000/1000000/996300/996237/b0bc3d3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/1000000/996300/996237/65fcf621.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Vending machine](https://images.trvl-media.com/lodging/1000000/1000000/996300/996237/67af2fe8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Television](https://images.trvl-media.com/lodging/1000000/1000000/996300/996237/28cfa176.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Motel 6 Altoona, IA - Des Moines East Altoona 6.0/10 (1002) "I will definitely stay there again!" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Fredrick CA $88 CA $98 total includes taxes & fees Dec 3 - Dec 4 [](https://www.expedia.ca/Des-Moines-Hotels-Motel-6-Altoona.h996237.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.ca/Hotel-Search?startDate=2025-12-16&endDate=2025-12-17®ionId=3000436816&adults=2&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in](https://expedia.ca/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCarlisle-Hotels-Motel-6.0-0-d3000436816--bMotel6.Travel-Guide-Filter-Hotels)[Sign up, it's free](https://expedia.ca/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCarlisle-Hotels-Motel-6.0-0-d3000436816--bMotel6.Travel-Guide-Filter-Hotels) ## Top Carlisle Hotel Reviews ![Home2 Suites by Hilton Des Moines at Drake University](https://images.trvl-media.com/lodging/49000000/48260000/48251500/48251406/b9f3330e_y.jpg) ### Home2 Suites by Hilton Des Moines at Drake University 10/10 Excellent "Great beds. Spacious rooms. Good breakfast!" [](https://expedia.ca/Des-Moines-Hotels-Home2-Suites-By-Hilton-Des-Moines-At-Drake-University.h48251406.Hotel-Information) ![Sonesta Essential Des Moines](https://images.trvl-media.com/lodging/1000000/60000/50800/50789/9b65231b_y.jpg) ### Sonesta Essential Des Moines 10/10 Excellent "Only thing I'd say needed to be done is I've noticed not every room has an ice bucket & don't understand the 3 pillow thing either. " [](https://expedia.ca/Des-Moines-Hotels-Sonesta-Essential-Des-Moines.h50789.Hotel-Information) ![Hyatt Place Des Moines/Downtown](https://images.trvl-media.com/lodging/4000000/3980000/3972200/3972152/c5d9ac95_y.jpg) ### Hyatt Place Des Moines/Downtown 10/10 Excellent "The room was very clean amd we had more an amazing stay" [](https://expedia.ca/Des-Moines-Hotels-Hyatt-Place-Des-Moines-Downtwn.h3972152.Hotel-Information) ![SpringHill Suites Des Moines West](https://images.trvl-media.com/lodging/1000000/560000/554000/553975/2e2cdb05_y.jpg) ### SpringHill Suites Des Moines West 10/10 Excellent "Comfy clean " [](https://expedia.ca/Des-Moines-Hotels-SpringHill-Suites-Des-Moines-West.h553975.Hotel-Information) ![Country Inn & Suites by Radisson, Des Moines West, IA](https://images.trvl-media.com/lodging/1000000/100000/99800/99780/cede0cf8_y.jpg) ### Country Inn & Suites by Radisson, Des Moines West, IA 10/10 Excellent "Friendly staff" [](https://expedia.ca/Des-Moines-Hotels-Country-Inn-Suites-By-Radisson.h99780.Hotel-Information) ![Drury Inn & Suites West Des Moines](https://images.trvl-media.com/lodging/2000000/1840000/1836200/1836184/2af2a76d_y.jpg) ### Drury Inn & Suites West Des Moines 10/10 Excellent "A wonderful place to stay." [](https://expedia.ca/Des-Moines-Hotels-Drury-Inn-Suites-West-Des-Moines.h1836184.Hotel-Information) ![Hyatt Place West Des Moines Jordan Creek](https://images.trvl-media.com/lodging/17000000/16120000/16112600/16112546/f70b7069_y.jpg) ### Hyatt Place West Des Moines Jordan Creek 10/10 Excellent "Amenities are spotless and service is wonderful " [](https://expedia.ca/Des-Moines-Hotels-Hyatt-Place-West-Des-Moines-Jordan-Creek.h16112546.Hotel-Information) ![Fairfield Inn and Suites by Marriott Des Moines West](https://images.trvl-media.com/lodging/1000000/80000/77600/77590/01d93670_y.jpg) ### Fairfield Inn and Suites by Marriott Des Moines West 10/10 Excellent "FULL SIZE PILLOWS! Clean room. Friendly and professional staff. Excellent breakfast. Greatly appreciate the FULL SIZE PILLOWS!" [](https://expedia.ca/Des-Moines-Hotels-Fairfield-Inn-And-Suites-By-Marriott-Des-Moines-West.h77590.Hotel-Information) ![Des Lux Hotel](https://images.trvl-media.com/lodging/10000000/9790000/9781500/9781455/e7f9fb30_y.jpg) ### Des Lux Hotel 10/10 Excellent "This hotel is absolutely beautiful. The most aesthetically pleasing place I've ever stayed. Everything was perfectly clean and the staff was super friendly and helpful. Best hotel breakfast I've had since pre-covid. I would have expected to pay much more for how lovely this place is. Cannot recommend enough." 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[Flights from Toronto (YYZ) to Des Moines (DSM)](https://www.expedia.ca/lp/flights/yyz/dsm/toronto-to-des-moines) - [Visit Iowa](https://www.expedia.ca/Iowa.dx217) - [Visit Pleasant Hill](https://www.expedia.ca/Pleasant-Hill.dx6060660) - [Sky Glider East](https://www.expedia.ca/Sky-Glider-East-Des-Moines.d553248621563219372.Vacation-Attraction) - [Rental cars Des Moines Intl. airport](https://www.expedia.ca/Car-Rentals-In-Des-Moines-Intl.d5067588.Car-Rental-Guide) - [Book Motel 6 in Carlisle on Expedia.com](https://www.expedia.com/Carlisle-Hotels-Motel-6.0-0-d3000436816--bMotel6.Travel-Guide-Filter-Hotels)