A historic building with a clock tower, surrounded by modern skyscrapers and a well-maintained lawn.

5 Stars Hotels in Wayne, Indianapolis from CA $259

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Check availability on Wayne 5 Star Hotels

Tonight
Sep 24 - Sep 25
Tomorrow
Sep 25 - Sep 26
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Wayne 5-star hotels

A person in a bathtub filled with bubbles, holding a glass of champagne, with a cake and flowers on the side.
A spacious indoor venue with multiple round tables and chairs, a glass ceiling, and a central staircase.
A high-rise hotel with multiple floors and a prominent "CONRAD" sign at the top.
A grand entrance with a checkered floor, double doors, and a sign reading 'THE CAPITAL GRILLE'.

1. Conrad Indianapolis

Conrad Indianapolis
Downtown Indianapolis
United States
Erick
CA $313
CA $370 total
includes taxes & fees
Sep 27 - Sep 28
Conrad Indianapolis
A hotel room with a bed, a seating area, a view of the cityscape, and a large window.
A modern dining area with a long table, chairs, and a unique wall design.
A modern building with a rooftop pool, outdoor seating, and a mural.
A modern lounge area with a curved wooden ceiling, seating arrangements, and a city view.

2. Signia Hilton Indianapolis

Signia Hilton Indianapolis
Downtown Indianapolis
Signia Hilton Indianapolis
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Wayne.
Ironworks Hotel Indy

Ironworks Hotel Indy

2721 E 86th Street Indianapolis IN
CA $260
CA $304 total
Sep 27 - Sep 28
includes taxes & fees
Ironworks Hotel Indy
Omni Severin Hotel

Omni Severin Hotel

40 West Jackson Place Indianapolis IN
CA $219
CA $259 total
Oct 24 - Oct 25
includes taxes & fees
9.4/10 Exceptional! (1,409 reviews)
Omni Severin Hotel
Bottleworks Hotel

Bottleworks Hotel

850 Massachusetts Avenue Indianapolis IN
CA $323
CA $379 total
Oct 12 - Oct 13
includes taxes & fees
Bottleworks Hotel
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Wayne

Check out the local area in Wayne—home to attractions like 8 Seconds Saloon and Rolls-Royce Heritage Trust.

See all hotels in Wayne
A historic building with a clock tower, surrounded by modern skyscrapers and a well-maintained lawn.

Top Wayne Hotel Reviews

Find out more about Wayne

Luxury is the name of the game at the best 5 Stars hotels in Wayne. If you want to vacation like a true VIP, these are the places to go; from spacious resorts to boutique-inspired hot spots, the top Wayne 5 Stars hotels are dedicated to immersing you in the ultimate experience. Want to relax with a serene treatment at a designer spa? These properties offer them.

Interested in tasting delicious dishes from top chefs? The gourmet restaurants at the 5 Stars Wayne hotels have you covered. You’ll even find first-class hotels near the city’s must-see attractions and most upscale entertainment districts. Plus, when you book your trip with Expedia.ca, you’ll get access to fantastic rates and seasonal discounts, so you can take advantage of a cheap deal on 5 Stars hotels Wayne without giving up even an inch of quality. Everything your heart desires (and a few perks designed to make it skip a beat): That’s what’s on offer when you plan a trip to the hotels with 5 Stars in Wayne.

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