Honeymoon Vacations in Southeast Minnesota 2026

Photo by Sara Crotts

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Honeymoon Hotels in Southeast Minnesota

Alexander Mansion Bed and Breakfast

274 East Broadway Winona MN

2 hours drive from Mayo Clinic

Stay at this B&B in Winona. Enjoy free parking, a business center, and daily housekeeping. Popular attractions Winona Arts Center and Watkins Heritage Museum ...

9.8/10 Exceptional! (547 reviews)

"Very nice BNB in downtown Winona. Staff was very friendly and room was spacious and comfortable."

Reviewed on Sep 5, 2026

Residence Inn by Marriott Rochester Mayo Clinic Area

441 W Center St Nw Rochester MN

4 min walk from Mayo Clinic

Stay at this hotel in Rochester. Enjoy free breakfast, free WiFi, and a rooftop terrace. Our guests praise the helpful staff in our reviews. Popular attractions ...

8.6/10 Excellent! (210 reviews)

"The staff were super friendly helpful and greet you with smile upon arrival at the check in. Our night staff offer us bottle of water as complimentary and I thought that was a very nice gesture other hotel could do as well."

Reviewed on Aug 27, 2026

St James Hotel, a Historic Hotel of America

406 Main St. Red Wing MN

2 hours drive from Mayo Clinic

Book a stay at this spa hotel in Red Wing. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the comfy rooms in ...

9.2/10 Wonderful! (1,012 reviews)

"Lovely room! Great view of river. Close to train tracks, but noise is not noticeable. Dinner in the hotel restaurant was delicious."

Reviewed on Sep 9, 2026

See all 942 properties in Southeast Minnesota

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.