Title: Adventure Vacations in Southeast Missouri 2026/2026 | Expedia.ca ![](https://images.trvl-media.com/place/148078/1ef720df-0786-4e45-8a4f-890d982b757b.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Southeast Missouri Adventure Vacations ## Book a Hotel + Flight or Car together to unlock savings Photo by JG Morris - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Adventure Hotels in Southeast Missouri ![Hampton Inn Farmington](https://images.trvl-media.com/lodging/4000000/3600000/3594600/3594547/3eea0c0d_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hampton Inn Farmington 850 Valley Creek Dr Farmington MO - 2 hours drive from Mark Twain National Forest Stay at this hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular attractions ... 8.8/10 Excellent! (518 reviews) Staff was amazing, super clean Reviewed on Nov 26, 2025 [](https://expedia.ca/Farmington-Hotels-Hampton-Inn-Farmington.h3594547.Hotel-Information) ![Crown Pointe Lodge, BW Signature Collection](https://images.trvl-media.com/lodging/2000000/1430000/1429500/1429479/83119f36_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Crown Pointe Lodge, BW Signature Collection 4245 Hunt Rd Farmington MO - 2 hours drive from Mark Twain National Forest Book a stay at this golf hotel in Farmington. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. Popular ... 8.8/10 Excellent! (572 reviews) The lady at the front was very kind and quick, which was nice because we were tired. Hottub was great and my son enjoyed the pool even though the heater was out. We definitely would stay again. Reviewed on Nov 30, 2025 [](https://expedia.ca/Farmington-Hotels-Crown-Pointe-Lodge.h1429479.Hotel-Information) ![Echo Bluff State Park](https://images.trvl-media.com/lodging/16000000/15490000/15487700/15487684/4071c448_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Echo Bluff State Park 34489 Echo Bluff Dr Eminence MO - 43 min drive from Mark Twain National Forest Book a stay at this business-friendly hotel in Eminence. Enjoy free WiFi, free parking, and a 24-hour front desk. Popular attractions Echo Bluff State Park and ... 9.4/10 Exceptional! (216 reviews) Fireplace was a nice surprise. Love that they had a ceiling fan. Staff was friendly and helpful. Reviewed on Nov 18, 2025 [](https://expedia.ca/Rolla-Hotels-Echo-Bluff-State-Park.h15487684.Hotel-Information) [See all 618 properties in Southeast Missouri](https://expedia.ca/Hotel-Search?rfrrid=TG.LP.Hotels.Package®ionId=6058763) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## More Vacations Ideas [Flights to Southeast Missouri ](https://expedia.ca/Cheap-Flights-To-Southeast-Missouri.d6058763.Travel-Guide-Flights)[ Southeast Missouri Hotels ](https://expedia.ca/Southeast-Missouri-Hotels.d6058763.Travel-Guide-Hotels)[ Southeast Missouri Vacation Rentals ](https://expedia.ca/Southeast-Missouri-Vacation-Rentals.d6058763.Travel-Guide-VacationRentals)[ Southeast Missouri Car Rentals ](https://expedia.ca/Car-Rentals-In-Southeast-Missouri.d6058763.Car-Rental-Guide)[ Southeast Missouri Vacations ](https://expedia.ca/Southeast-Missouri.d6058763.Destination-Travel-Guides)[ Things to do in Southeast Missouri ](https://expedia.ca/Things-To-Do-In-Southeast-Missouri.d6058763.Travel-Guide-Activities) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app