
Eastern Panama Adults Only Vacations
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Flight and Adults Only hotel deals in Eastern Panama
Price found within the past 48 hours. Click for updated prices.

Yoo by Wynwood House
Calidonia
Price was CA $2,257, price is now CA $1,770 per person
CA $1,770
per person
Jun 24 - Jul 1
found 1 day ago
Roundtrip non-stop flight included
Montreal (YUL) to Panama City (PTY)
9.4/10 Exceptional! (6 reviews)
Unfortunately the name of the property was not Yoo by Wynwood. It is P. H. Yoo Panama & Arts Tower. This detail that was incorrect cost us time, money and stress at the beginning of our trip. We weren't able to get in touch with anyone at the property or at expedia and we ended up having to cross reference google photos to figure out the correct name and address of the location. This took us about an hour to do in a Country that we had never been to. We are very displeased with Expedia about this. We still have not been contacted by anyone.
Reviewed on Jul 26, 2025

Central Hotel Panama Casco Viejo
Casco Viejo
Price was CA $3,450, price is now CA $2,248 per person
CA $2,248
per person
Jun 19 - Jun 26
found 16 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to Panama City (PTY)
9.2/10 Wonderful! (1,017 reviews)
Very nice and clean hotel in the centralized area. It is very safe to walk all over the place.
Reviewed on May 11, 2026

Megapolis Hotel Panamá
San Francisco
Price was CA $2,774, price is now CA $1,934 per person
CA $1,934
per person
Jun 19 - Jun 26
found 16 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to Panama City (PTY)
8.4/10 Very Good! (1,524 reviews)
Staff at fron desk did they best to help me changing the dates that i booked by mistake also hotel's staff in general was outstanding this is my firs choice wen i stay in Panama City.
Reviewed on May 20, 2026

Casa Mallet by Wynwood House
Casco Viejo
Price was CA $2,866, price is now CA $2,149 per person
CA $2,149
per person
Jul 26 - Aug 2
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
9.8/10 Exceptional! (27 reviews)
In the middle of the old town, lovely rooftop. Beautiful apartment. Easy check in. WhatsApp line is available if anything was needed or if we had questions.
Reviewed on Mar 12, 2026

Hilton Panama
Bella Vista
Price was CA $2,697, price is now CA $2,083 per person
CA $2,083
per person
Jul 26 - Aug 2
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
9/10 Wonderful! (1,008 reviews)
First class hotel in downtown with excellent view from pool and restaurant area on high floor (really pleasant at night).
Many dining options and not far from Panama Canal and old city.
Reviewed on Apr 30, 2026
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View all trips5* Adults Only holidays in Eastern Panama
Price found within the past 48 hours. Click for updated prices.

Hilton Panama
Bella Vista
Price was CA $2,697, price is now CA $2,083 per person
CA $2,083
per person
Jul 26 - Aug 2
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
9/10 Wonderful! (1,008 reviews)
First class hotel in downtown with excellent view from pool and restaurant area on high floor (really pleasant at night).
Many dining options and not far from Panama Canal and old city.
Reviewed on Apr 30, 2026

The Santa Maria, A Luxury Collection Hotel & Golf Resort, Panama City
Juan Diaz
Price was CA $2,658, price is now CA $2,093 per person
CA $2,093
per person
Jul 13 - Jul 20
found 15 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to Panama City (PTY)
9.6/10 Exceptional! (694 reviews)
This is the definition of a 5 start hotel.
We went to celebrate my husbands birthday because he's an avid golfer. It was easy to book tee times and the service was impeccable.
The course was wel maintained and even saw a crocodile.
The hotel itself went above and beyond because our room wasn't ready at time of arrival.
Reviewed on Apr 5, 2026

Sofitel Legend Casco Viejo, Panama City
Casco Viejo
Price was CA $2,892, price is now CA $2,294 per person
CA $2,294
per person
Jul 13 - Jul 20
found 15 hours ago
Roundtrip non-stop flight included
Edmonton (YEG) to Panama City (PTY)
9.8/10 Exceptional! (648 reviews)
Easily one the best hotel stays ever. Great property. Great food. Excellent service.
Reviewed on May 14, 2026
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Price found within the past 48 hours. Click for updated prices.

Central Hotel Panama Casco Viejo
Casco Viejo
Price was CA $1,528, price is now CA $1,246 per person
CA $1,246
per person
Jul 22 - Jul 24
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Panama City (PTY)
9.2/10 Wonderful! (1,017 reviews)
Very nice and clean hotel in the centralized area. It is very safe to walk all over the place.
Reviewed on May 11, 2026

Megapolis Hotel Panamá
San Francisco
Price was CA $1,562, price is now CA $1,247 per person
CA $1,247
per person
Jul 22 - Jul 24
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Panama City (PTY)
8.4/10 Very Good! (1,524 reviews)
Staff at fron desk did they best to help me changing the dates that i booked by mistake also hotel's staff in general was outstanding this is my firs choice wen i stay in Panama City.
Reviewed on May 20, 2026

Dreams Playa Bonita Panama - All Inclusive
Price was CA $1,709, price is now CA $1,426 per person
CA $1,426
per person
Jul 22 - Jul 24
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Panama City (PTY)
7.6/10 Good! (1,001 reviews)
Quiero dejar un reconocimiento especial para dos empleados del pool bar, Russell y Avery, quienes hicieron nuestra experiencia increíble. Fueron amables, atentos y siempre con una excelente actitud. Realmente fueron lo máximo.
Además, todos los empleados del hotel fueron magníficos y nos hicieron sentir muy bien atendidos durante toda la estadía. Sin duda, un servicio excepcional que hizo la diferencia.
Reviewed on May 18, 2026
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View all trips4 Night Adults Only holidays in Eastern Panama
Price found within the past 48 hours. Click for updated prices.

Hilton Panama
Bella Vista
Price was CA $1,872, price is now CA $1,537 per person
CA $1,537
per person
Jul 31 - Aug 4
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Panama City (PTY)
9/10 Wonderful! (1,008 reviews)
First class hotel in downtown with excellent view from pool and restaurant area on high floor (really pleasant at night).
Many dining options and not far from Panama Canal and old city.
Reviewed on Apr 30, 2026

Central Hotel Panama Casco Viejo
Casco Viejo
Price was CA $3,123, price is now CA $2,057 per person
CA $2,057
per person
Jul 5 - Jul 9
found 1 day ago
Roundtrip non-stop flight included
Toronto (YYZ) to Panama City (PTY)
9.2/10 Wonderful! (1,017 reviews)
Very nice and clean hotel in the centralized area. It is very safe to walk all over the place.
Reviewed on May 11, 2026

Megapolis Hotel Panamá
San Francisco
Price was CA $2,220, price is now CA $1,706 per person
CA $1,706
per person
Jun 27 - Jul 1
found 1 day ago
Roundtrip non-stop flight included
Toronto (YTO) to Panama City (PTY)
8.4/10 Very Good! (1,524 reviews)
Staff at fron desk did they best to help me changing the dates that i booked by mistake also hotel's staff in general was outstanding this is my firs choice wen i stay in Panama City.
Reviewed on May 20, 2026
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