Title: Adults Only Vacations in Mayo River 2026/2026 | Expedia.ca ![](https://images.trvl-media.com/place/553248621561864249/54558157-d5bc-4ba5-a77d-f9a917492c5a.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Mayo River Adults Only Vacations ## Book a Hotel + Flight or Car together to unlock savings Photo by Ed Mayfield - ## Plan, book, travel with confidence - ### Better together Save up to CA $1,096 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Flight and Adults Only hotel deals in Mayo River Price found within the past 48 hours. Click for updated prices. ![DoubleTree by Hilton Greensboro Airport](https://images.trvl-media.com/lodging/1000000/180000/180000/179947/82545d4c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### DoubleTree by Hilton Greensboro Airport CA $704 per person Feb 25 - Feb 27 found 1 day ago Roundtrip flight included Calgary (YYC) to Greensboro (GSO) 8.8/10 Excellent! (817 reviews) CLEAN ROOM VERY WELL MAINTAINED Reviewed on Dec 7, 2025 ![O.Henry Hotel](https://images.trvl-media.com/lodging/1000000/210000/200700/200643/c925edd0_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### O.Henry Hotel CA $919 per person Feb 25 - Feb 27 found 1 day ago Roundtrip flight included Calgary (YYC) to Greensboro (GSO) 9.8/10 Exceptional! (724 reviews) Nice place to Stay in Greensboro, NC. I didn’t anticipate the country club warm vibe in a Metropolitan area. Reviewed on Dec 6, 2025 ![Proximity Hotel](https://images.trvl-media.com/lodging/2000000/1730000/1725300/1725222/69182f7e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Proximity Hotel CA $1,003 per person Feb 25 - Feb 27 found 1 day ago Roundtrip flight included Calgary (YYC) to Greensboro (GSO) 9.6/10 Exceptional! (879 reviews) Very nice stay for 25th Anniversary. Reviewed on Dec 6, 2025 ![Marriott Greensboro Downtown](https://images.trvl-media.com/lodging/1000000/30000/28400/28374/505b8ec3_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Marriott Greensboro Downtown Downtown Greensboro CA $1,011 per person Feb 25 - Feb 27 found 1 day ago Roundtrip flight included Calgary (YYC) to Greensboro (GSO) 8.6/10 Excellent! (1,002 reviews) We thought overall the property and room was nice. However, I had reserved a room with a “roll” in shower because my husband is handicapped and can’t step over a tub edge. We were given room with tub. An outlet in our room was hanging by wires near bed. Room service food arrived cold. Then when we checked the hotel held TWICE the amount of my CC for our two night stay, that is unacceptable. Reviewed on Dec 6, 2025 Don't see what you're looking for? See all available trips from Columbus to Mayo River [View all trips](https://expedia.ca/go/package/search/FlightHotel/2026-01-08/2026-01-15/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=GSO&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## 3 Night Adults Only holidays in Mayo River Price found within the past 48 hours. Click for updated prices. ![DoubleTree by Hilton Greensboro Airport](https://images.trvl-media.com/lodging/1000000/180000/180000/179947/82545d4c_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### DoubleTree by Hilton Greensboro Airport CA $914 per person Feb 14 - Feb 17 found 1 day ago Roundtrip flight included Calgary (YYC) to Greensboro (GSO) 8.8/10 Excellent! (817 reviews) CLEAN ROOM VERY WELL MAINTAINED Reviewed on Dec 7, 2025 Don't see what you're looking for? See all available trips from Columbus to Mayo River [View all trips](https://expedia.ca/go/package/search/FlightHotel/2026-01-08/2026-01-15/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=GSO&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.ca/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.ca/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Family Vacations [](https://expedia.ca/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Family_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.ca/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.ca/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.ca/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.ca/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ## More Vacations Ideas [Flights to Mayo River ](https://expedia.ca/Cheap-Flights-To-Mayo-River.d553248635976006279.Travel-Guide-Flights)[ Mayo River Hotels ](https://expedia.ca/Mayo-River-Hotels.d553248635976006279.Travel-Guide-Hotels)[ Mayo River Vacation Rentals ](https://expedia.ca/Mayo-River-Vacation-Rentals.d553248635976006279.Travel-Guide-VacationRentals)[ Mayo River Car Rentals ](https://expedia.ca/Car-Rentals-In-Mayo-River.d553248635976006279.Car-Rental-Guide)[ Mayo River Vacations ](https://expedia.ca/Mayo-River.d553248635976006279.Destination-Travel-Guides) \* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages. ![](https://a.travel-assets.com/mad-service/footer/bnaBanners/BEX_Footer.jpg) ## Go further with the Expedia app Save on select hotels and earn double points when you book on the app. Our app deals help you to save on trips so you can travel more and manage it all on the go. Scan the QR code with your device camera and download our app