Title: CA $484 Cheap Flights from Panama City (PTY) to San Francisco (SFO) - Expedia.ca ![Sunset view of the Golden Gate Bridge and fog from Battery Spencer, Golden Gate National Recreation Area, in San Francisco, California.](https://images.trvl-media.com/place/508803/0ac688ba-e7fa-4fb1-9f85-037d98869bf8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/508803/0ac688ba-e7fa-4fb1-9f85-037d98869bf8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # CA $484 Cheap Flights from Panama City (PTY) to San Francisco (SFO) [View CA $484 flight on Tue, Dec 23, 2025](https://expedia.ca/Flights-Search?trip=oneway&leg1=from:PTY,to:SFO,departure:23/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:483.80&airProductToken=AQprCjQIwZoBEgM0NjUY78QBIIy5ASjrwIADMODCgAM4UkAAWAFqB0NMQVNJQ0FyCFJOTk4wNENTCjMIwZoBEgM2NjQYjLkBILJxKMTNgAMw9M-AAzhSQAFYAWoHQ0xBU0lDQXIIUk5OTjA0Q1MSCggBEAEYASoCQU0YASIECAEQASgCKAMoBDAB) - [Roundtrip](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Tocumen Intl. Airport (PTY) to San Francisco International Airport (SFO) - ![Avianca](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg) Avianca [](https://www.expedia.ca/Flights-Search?leg1=from:pty,to:sfo,departure:16/11/2025TANYT&leg2=from:sfo,to:pty,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}]) - ![Copa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_CM.svg) Copa [](https://www.expedia.ca/Flights-Search?leg1=from:pty,to:sfo,departure:16/11/2025TANYT&leg2=from:sfo,to:pty,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"CM"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.ca/Flights-Search?leg1=from:pty,to:sfo,departure:16/11/2025TANYT&leg2=from:sfo,to:pty,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Aeromexico](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AM.svg) Aeromexico [](https://www.expedia.ca/Flights-Search?leg1=from:pty,to:sfo,departure:16/11/2025TANYT&leg2=from:sfo,to:pty,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AM"}}]) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.ca/Flights-Search?leg1=from:pty,to:sfo,departure:16/11/2025TANYT&leg2=from:sfo,to:pty,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.ca/Flights-Search?leg1=from:pty,to:sfo,departure:16/11/2025TANYT&leg2=from:sfo,to:pty,departure:23/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 30% on select hotels after you book a flight\* - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.ca/login) ## Cheap flights from Panama City (PTY) to San Francisco (SFO) Prices were available within the past 7 days and start at CA $484 for one-way flights and CA $912 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Thu, Dec 25 - Wed, Dec 31 PTY Panama City SFO San Francisco CA $912 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:SFO,departure:25/12/2025TANYT&leg2=from:SFO,to:PTY,departure:31/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:911.37&airProductToken=AQpnCjIIwYIBEgQyOTY0GO_EASCMAiip14ADMOvYgAM4QkAAWAFqBUJBU0lDcghOTk41TlRCWgoxCMGCARIEMzE0MhiMAiCycSjv2YADMP_cgAM4QkABWAFqBUJBU0lDcghOTk41TlRCWgpmCjEIwYIBEgQxMzAxGLJxIIwCKO-fgQMwt6KBAzhCQABYAWoFQkFTSUNyCE5OTjVOVEJaCjEIwYIBEgMzMTUYjAIg78QBKPmjgQMwzaWBAzhCQAFYAWoFQkFTSUNyCE5OTjVOVEJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Thu, Dec 25 - Wed, Dec 31 PTY Panama City SFO San Francisco CA $912 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:SFO,departure:25/12/2025TANYT&leg2=from:SFO,to:PTY,departure:31/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:911.37&airProductToken=AQpuCjYIxJgBEgQxOTA0GO_EASDgXCiM1IADMJLWgAM4RUAAWAFqCU1BSU5CQVNJQ3IIVk5OUTFOQloKNAjEmAESAzgyMxjgXCCycSim14ADMOPZgAM4RUABWAFqCU1BSU5CQVNJQ3IIVk5OUTFOQloKbgo0CMSYARIDOTMwGLJxIOBcKKKggQMwtaKBAzhFQABYAWoJTUFJTkJBU0lDcghWTk5RMU5CWgo2CMSYARIEMTkwNRjgXCDvxAEozaaBAzC8qIEDOEVAAVgBaglNQUlOQkFTSUNyCFZOTlExTkJaEgoIARABGAEqAkRMGAEiBAgBEAEoAigDKAQwAQ) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Tue, Dec 23 - Wed, Jan 14 PTY Panama City SFO San Francisco CA $914 Roundtrip found 6 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:SFO,departure:23/12/2025TANYT&leg2=from:SFO,to:PTY,departure:14/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:913.98&airProductToken=AQpmCjEIwYIBEgMzMzYY78QBIIwCKOPBgAMwpcOAAzhCQABYAWoFQkFTSUNyCE5OTjVOVEJaCjEIwYIBEgQzMTE3GIwCILJxKOLIgAMw3cuAAzhCQAFYAWoFQkFTSUNyCE5OTjVOVEJaCpsBCjIIwYIBEgQ2NDUxGLJxIIu4ASiDuIIDMN-4ggM4QkAAWAFqBUJBU0lDcghOTk41TlRCWgoyCMGCARIEMTEwMxiLuAEgjAIosbmCAzDZu4IDOEJAAVgBagVCQVNJQ3IITk5ONU5UQloKMQjBggESAzMxORiMAiDvxAEos8GCAzDzwoIDOEJAAVgBagVCQVNJQ3IITk5ONU5UQloSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) ![Aeromexico](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/am.gif) Tue, Dec 23 - Wed, Jan 14 PTY Panama City SFO San Francisco CA $932 Roundtrip found 6 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:SFO,departure:23/12/2025TANYT&leg2=from:SFO,to:PTY,departure:14/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:931.68&airProductToken=AQprCjQIwZoBEgM0NjUY78QBIIy5ASjrwIADMODCgAM4UkAAWAFqB0NMQVNJQ0FyCFJOTk4wNENTCjMIwZoBEgM2NjQYjLkBILJxKMTNgAMw9M-AAzhSQAFYAWoHQ0xBU0lDQXIIUk5OTjA0Q1MSCggBEAEYASoCQU0YASIECAEQASgCKAMoBDAB) ![Aeromexico](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/am.gif) Tue, Dec 23 - Wed, Jan 14 PTY Panama City SFO San Francisco CA $946 Roundtrip found 6 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:SFO,departure:23/12/2025TANYT&leg2=from:SFO,to:PTY,departure:14/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:945.68&airProductToken=AQprCjQIwZoBEgM0NjUY78QBIIy5ASjrwIADMODCgAM4UkAAWAFqB0NMQVNJQ0FyCFJOTk4wNENTCjMIwZoBEgM2NjQYjLkBILJxKMTNgAMw9M-AAzhSQAFYAWoHQ0xBU0lDQXIIUk5OTjA0Q1MSCggBEAEYASoCQU0YASIECAEQASgCKAMoBDAB) ![Aeromexico](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/am.gif) Tue, Dec 23 - Fri, Jan 9 PTY Panama City SFO San Francisco CA $948 Roundtrip found 6 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:SFO,departure:23/12/2025TANYT&leg2=from:SFO,to:PTY,departure:09/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:947.50&airProductToken=AQprCjQIwZoBEgM0NjUY78QBIIy5ASjrwIADMODCgAM4UkAAWAFqB0NMQVNJQ0FyCFJOTk4wNENTCjMIwZoBEgM2NjQYjLkBILJxKMTNgAMw9M-AAzhSQAFYAWoHQ0xBU0lDQXIIUk5OTjA0Q1MSCggBEAEYASoCQU0YASIECAEQASgCKAMoBDAB) ![Aeromexico](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/am.gif) Tue, Dec 23 - Wed, Jan 14 PTY Panama City SFO San Francisco CA $956 Roundtrip found 6 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:SFO,departure:23/12/2025TANYT&leg2=from:SFO,to:PTY,departure:14/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:955.48&airProductToken=AQprCjQIwZoBEgM0NjUY78QBIIy5ASjrwIADMODCgAM4UkAAWAFqB0NMQVNJQ0FyCFJOTk4wNENTCjMIwZoBEgM2NjQYjLkBILJxKMTNgAMw9M-AAzhSQAFYAWoHQ0xBU0lDQXIIUk5OTjA0Q1MSCggBEAEYASoCQU0YASIECAEQASgCKAMoBDAB) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Sat, Dec 20 - Tue, Jan 13 PTY Panama City SFO San Francisco CA $975 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:SFO,departure:20/12/2025TANYT&leg2=from:SFO,to:PTY,departure:13/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:974.47&airProductToken=AQqZAQoyCMGCARIEMjk2NBjvxAEgjAIoiZ-AAzDLoIADOEJAAFgBagVCQVNJQ3IIU05OOElIQloKMQjBggESBDE5MTgYjAIgrhwo1qGAAzCro4ADOEJAAVgBagVCQVNJQ3IIU05OOElIQloKMAjBggESAzkyOBiuHCCycSjTp4ADMPupgAM4QkABWAFqBUJBU0lDcghTTk44SUhCWgqbAQoyCMGCARIEMTk5NhiycSCjsQEoh62CAzDYroIDOEJAAFgBagVCQVNJQ3IITk5ONU5UQloKMgjBggESBDEwNDIYo7EBIIwCKJS0ggMwvrWCAzhCQAFYAWoFQkFTSUNyCE5OTjVOVEJaCjEIwYIBEgMzMTkYjAIg78QBKJO2ggMw07eCAzhCQAFYAWoFQkFTSUNyCE5OTjVOVEJaEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Tue, Dec 23 - Wed, Jan 14 PTY Panama City SFO San Francisco CA $977 Roundtrip found 6 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:SFO,departure:23/12/2025TANYT&leg2=from:SFO,to:PTY,departure:14/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:976.08&airProductToken=AQpmCjEIwYIBEgMzMzYY78QBIIwCKOPBgAMwpcOAAzhCQABYAWoFQkFTSUNyCE5OTjVOVEJaCjEIwYIBEgQzMTE3GIwCILJxKOLIgAMw3cuAAzhCQAFYAWoFQkFTSUNyCE5OTjVOVEJaCpsBCjIIwYIBEgQyMTc3GLJxIKOxASjMuYIDMKK7ggM4QkAAWAFqBUJBU0lDcghTTk44SUhCWgoyCMGCARIEMTMxNBijsQEgjAIo47uCAzCGvYIDOEJAAVgBagVCQVNJQ3IIU05OOElIQloKMQjBggESAzMxORiMAiDvxAEos8GCAzDzwoIDOEJAAVgBagVCQVNJQ3IIU05OOElIQloSCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Tue, Dec 23 - Wed, Jan 14 PTY Panama City SFO San Francisco CA $1,051 Roundtrip found 6 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:SFO,departure:23/12/2025TANYT&leg2=from:SFO,to:PTY,departure:14/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:1050.58&airProductToken=AQppCjMIwawBEgMzMjIY78QBIJJYKKLBgAMwmsKAAzhTQABYAWoHQ0xBU1NJQ3IIU0VPQjJCUkYKMgjBrAESAzU1OBiSWCCycSiXw4ADMJjGgAM4U0ABWAFqB0NMQVNTSUNyCFNFT0IyQlJGCmkKMgjBrAESAzU1ORiycSCSWCi_s4IDMIm2ggM4U0AAWAFqB0NMQVNTSUNyCFNFT0IyQlJGCjMIwawBEgMzMTcYklgg78QBKJm5ggMwm7qCAzhTQAFYAWoHQ0xBU1NJQ3IIU0VPQjJCUkYSCggBEAEYASoCTFIYASIECAEQASgCKAMoBDAB) ## Find the cheapest month to fly from Panama City (PTY) to San Francisco (SFO) ### September is typically the cheapest month to fly From CA $653 - CA $943 per traveller. Flight from Panama City to San Francisco (PTY - SFO) route information | Origin airport | Tocumen Intl. | | --- | --- | | Destination airport | San Francisco Intl. | | Airlines serving | Aeromexico, American Airlines, Delta, avianca | | Roundtrip price | CA $911 | | Distance | 5313 km | | Average flight time | 4 hours 52 mins | ## Tocumen to San Francisco Flights **The easy way to book your flights from Panama City to San Francisco**  With Expedia, it’s simple to find and book flights to San Francisco from Panama City whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to San Francisco Intl., too.   Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Panama City to San Francisco today, tomorrow, or this week.   **Save dollars with cheap flights from Tocumen Intl., PTY to San Francisco Intl., SFO**  Sort your search results by price to find great deals on your flight from Panama City to San Francisco—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to San Francisco from Panama City currently is just CA $912 rising to CA $1,558.   Here are more money-saving tips:  - Fly in December when flight prices are normally at their lowest  - Book about a month to 6 weeks before you travel for the best prices to San Francisco   - Avoid peak season and weekends when flights can cost more - Early morning and late-night flights are sometimes cheaper, so try varying your travel times  - One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free!  **Reasons to choose Expedia for your flight to San Francisco from Panama City**  Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to San Francisco with Expedia today. ## Frequently asked questions ### How much is a flight from Tocumen Intl. Airport (PTY) to SFO? > The lowest price advertised for a round-trip journey between Panama Airport and San Francisco Airport is CA $912. But you better get moving. This figure is taken from fares offered within the last 7 days on Expedia for flights departing within the next year. Prices and availability are subject to change. Additional terms apply. ### Do I need to pay a cancellation fee if I cancel my flight from Panama Airport to San Francisco Airport? > This varies between airlines, as each has its own set of terms and conditions. Head to the [Customer Service Portal](https://www.expedia.ca/helpcenter), where there are simple instructions on how to cancel your flight online. ### How do I find cheap flights from Tocumen Intl. Airport (PTY) to San Francisco Airport that have flexible change policies? > Many carriers offer the option to reschedule your flight at no extra charge. All you pay is the difference in the ticket price. When looking for PTY to San Francisco Intl. Airport (SFO) flights, you'll see a "No change fees" box for you to select. ### How many hours is the flight from Tocumen Intl. Airport (PTY) to San Francisco Airport? > The flight time between PTY and San Francisco Airport is 14 hours and 44 minutes. If you get peckish on longer flights, pack some healthy snacks in your carry-on bag. ### How far is the flight from PTY to San Francisco Airport? > You'll have 5,400 kilometres to cover on the long-haul Tocumen to San Francisco route. Wear layers of comfy clothes and consider taking a neck pillow with you. ### Which airlines fly direct from Panama Airport to San Francisco Airport? > A popular option with many frequent travellers, Copa Airlines (CM) operates 43 flights monthly from Tocumen Intl. Airport (PTY) to San Francisco Airport. Pick the one that fits with your travel plans and book your seat today. ### Are Panama Airport to SFO flight tickets cheaper when they're purchased at the last minute? > It is possible to score an awesome last-minute deal from Panama Airport to SFO, but it's also possible to miss out entirely! As many airlines release seats up to a year in advance, it's worth keeping an eye on fares early and being ready to book when you see a good bargain. 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