Title: CA $342 Cheap Flights from Panama City (PTY) to Guayaquil (GYE) - Expedia.ca ![](https://images.trvl-media.com/place/1414/5a1b814f-6172-4234-8e22-f7c4f67d6424.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/1414/5a1b814f-6172-4234-8e22-f7c4f67d6424.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # CA $342 Cheap Flights from Panama City (PTY) to Guayaquil (GYE) [View CA $342 flight on Sat, Nov 29, 2025](https://expedia.ca/Flights-Search?trip=oneway&leg1=from:PTY,to:GYE,departure:29/11/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:341.30&airProductToken=AQppCjIIwawBEgI0MRjvxAEgwTMom63-AjCErv4COFNAAFgBagdDTEFTU0lDcghTRU9CMkJSOQozCMGsARIEODM4NRjBMyCGJiikr_4CMJew_gI4U0ABWAFqB0NMQVNTSUNyCFNFT0IyQlI5EgoIARABGAEqAkxSGAEiBAgBEAEoAigDKAQwAQ) - [Roundtrip](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Tocumen Intl. Airport (PTY) to Jose Joaquin de Olmedo Intl. Airport (GYE) - ![Avianca](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AV.svg) Avianca [](https://www.expedia.ca/Flights-Search?leg1=from:PTY,to:GYE,departure:03/12/2025TANYT&leg2=from:GYE,to:PTY,departure:10/12/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AV"}}]) - ![Copa](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_CM.svg) Copa [](https://www.expedia.ca/Flights-Search?leg1=from:PTY,to:GYE,departure:03/12/2025TANYT&leg2=from:GYE,to:PTY,departure:10/12/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"CM"}}]) - ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 30% on select hotels after you book a flight\* - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.ca/login) ## Cheap flights from Panama City (PTY) to Guayaquil (GYE) Prices were available within the past 7 days and start at CA $342 for one-way flights and CA $639 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Sun, Mar 29 - Tue, Apr 21 PTY Panama City GYE Guayaquil CA $639 Roundtrip found 12 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:GYE,departure:29/03/2026TANYT&leg2=from:GYE,to:PTY,departure:21/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:638.50&airProductToken=AQozCjEIw5oBEgMyNTgY78QBIIYmKKD3iAMwpfiIAzhFQABYAWoFQkFTSUNyCEVMQTJUWTJTCjMKMQjDmgESAzM3NxiGJiDvxAEosPqKAzCw-4oDOEVAAFgBagVCQVNJQ3IIRUxBMlRZMlMSCggBEAEYASoCQ00YASIECAEQASgCKAMoBDAB) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Sun, Mar 29 - Tue, Apr 21 PTY Panama City GYE Guayaquil CA $654 Roundtrip found 12 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:GYE,departure:29/03/2026TANYT&leg2=from:GYE,to:PTY,departure:21/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:653.50&airProductToken=AQozCjEIw5oBEgMyNTgY78QBIIYmKKD3iAMwpfiIAzhFQABYAWoFQkFTSUNyCEVMQTJUWTJTCjMKMQjDmgESAzMwMBiGJiDvxAEozviKAzDN-YoDOEVAAFgBagVCQVNJQ3IIRUFBMlRZMlMSCggBEAEYASoCQ00YASIECAEQASgCKAMoBDAB) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Sun, Apr 19 - Mon, Apr 20 PTY Panama City GYE Guayaquil CA $677 Roundtrip found 12 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:GYE,departure:19/04/2026TANYT&leg2=from:GYE,to:PTY,departure:20/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:677.00&airProductToken=AQozCjEIw5oBEgMyNTgY78QBIIYmKLHjigMwuuSKAzhXQABYAWoFQkFTSUNyCFdMQTRUWTJTCjMKMQjDmgESAzM3NxiGJiDvxAEokO-KAzCQ8IoDOEVAAFgBagVCQVNJQ3IIRUxBMlRZMlMSCggBEAEYASoCQ00YASIECAEQASgCKAMoBDAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Thu, Dec 25 - Sat, Dec 27 PTY Panama City GYE Guayaquil CA $678 Roundtrip found 4 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:GYE,departure:25/12/2025TANYT&leg2=from:GYE,to:PTY,departure:27/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:677.90&airProductToken=AQppCjIIwawBEgI1ORjvxAEgwTMo9dSAAzDU1YADOFNAAFgBagdDTEFTU0lDcghTRU9CMkJSOQozCMGsARIEODM4MxjBMyCGJijY14ADMNXYgAM4U0ABWAFqB0NMQVNTSUNyCFNFT0IyQlI5CmkKMwjBrAESBDgzODAYhiYgwTMovuiAAzCx6YADOFNAAFgBagdDTEFTU0lDcghTRU9CMkJSOQoyCMGsARICNDAYwTMg78QBKNXxgAMwyPKAAzhTQAFYAWoHQ0xBU1NJQ3IIU0VPQjJCUjkSCggBEAEYASoCTFIYASIECAEQASgCKAMoBDAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Sun, Apr 19 - Mon, Apr 20 PTY Panama City GYE Guayaquil CA $680 Roundtrip found 12 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:GYE,departure:19/04/2026TANYT&leg2=from:GYE,to:PTY,departure:20/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:679.10&airProductToken=AQpnCjIIwawBEgI0MRjvxAEgwTMo1N-KAzCy4IoDOFNAAFgBagdDTEFTU0lDcghTRU9CMkJSOQoxCMGsARICOTEYwTMghiYo7OGKAzDf4ooDOFNAAVgBagdDTEFTU0lDcghTRU9CMkJSOQppCjMIwawBEgQ4Mzc0GIYmIMEzKKvrigMwnuyKAzhTQABYAWoHQ0xBU1NJQ3IIU0VPQjJCUjkKMgjBrAESAjYwGMEzIO_EASic8IoDMIrxigM4U0ABWAFqB0NMQVNTSUNyCFNFT0IyQlI5EgoIARABGAEqAkxSGAEiBAgBEAEoAigDKAQwAQ) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Sun, Apr 19 - Mon, Apr 20 PTY Panama City GYE Guayaquil CA $692 Roundtrip found 12 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:GYE,departure:19/04/2026TANYT&leg2=from:GYE,to:PTY,departure:20/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:692.00&airProductToken=AQozCjEIw5oBEgMyNTgY78QBIIYmKLHjigMwuuSKAzhXQABYAWoFQkFTSUNyCFdMQTRUWTJTCjMKMQjDmgESAzMwMBiGJiDvxAEoru2KAzCt7ooDOEVAAFgBagVCQVNJQ3IIRUFBMlRZMlMSCggBEAEYASoCQ00YASIECAEQASgCKAMoBDAB) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Sun, Mar 29 - Tue, Apr 21 PTY Panama City GYE Guayaquil CA $700 Roundtrip found 12 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:GYE,departure:29/03/2026TANYT&leg2=from:GYE,to:PTY,departure:21/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:699.50&airProductToken=AQozCjEIw5oBEgMzMTEY78QBIIYmKID8iAMwh_2IAzhXQABYAWoFQkFTSUNyCFdBQTRUWTJTCjMKMQjDmgESAzMxMxiGJiDvxAEotveKAzC4-IoDOEVAAFgBagVCQVNJQ3IIRUxBMlRZMlMSCggBEAEYASoCQ00YASIECAEQASgCKAMoBDAB) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Sun, Mar 29 - Tue, Apr 21 PTY Panama City GYE Guayaquil CA $715 Roundtrip found 12 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:GYE,departure:29/03/2026TANYT&leg2=from:GYE,to:PTY,departure:21/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:714.50&airProductToken=AQozCjEIw5oBEgMzMDEY78QBIIYmKPD7iAMw9fyIAzhXQABYAWoFQkFTSUNyCFdBQTRUWTJTCjMKMQjDmgESAzMwMBiGJiDvxAEozviKAzDN-YoDOEVAAFgBagVCQVNJQ3IIRUFBMlRZMlMSCggBEAEYASoCQ00YASIECAEQASgCKAMoBDAB) ![avianca](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/av.gif) Tue, Dec 2 - Sat, Dec 6 PTY Panama City GYE Guayaquil CA $721 Roundtrip found 2 days ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:GYE,departure:02/12/2025TANYT&leg2=from:GYE,to:PTY,departure:06/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:721.00&airProductToken=AQqdAQoyCMGsARICNTcY78QBIMEzKPrV_gIw3tb-AjhTQABYAWoHQ0xBU1NJQ3IIU0VPQjJCUjkKMgjBrAESAzEyNRjBMyCUcij51_4CMOLY_gI4U0ABWAFqB0NMQVNTSUNyCFNFT0IyQlI5CjMIwawBEgQxNjMyGJRyIIYmKNbc_gIwjd3-AjhTQAFYAWoHQ0xBU1NJQ3IIU0VPQjJCUjkKaQozCMGsARIEODM4NBiGJiDBMyi9__4CMKuA_wI4U0AAWAFqB0NMQVNTSUNyCFNFT0IyQlI5CjIIwawBEgI1OBjBMyDvxAEolYn_AjD-if8COFNAAVgBagdDTEFTU0lDcghTRU9CMkJSORIKCAEQARgBKgJMUhgBIgQIARABKAIoAygEMAE) ![Copa](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/CM.gif) Sun, Mar 29 - Tue, Apr 21 PTY Panama City GYE Guayaquil CA $731 Roundtrip found 12 hours ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:PTY,to:GYE,departure:29/03/2026TANYT&leg2=from:GYE,to:PTY,departure:21/04/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:730.50&airProductToken=AQozCjEIw5oBEgMzNzgY78QBIIYmKIP5iAMwiPqIAzhPQABYAWoFQkFTSUNyCE9BQTdUWTJTCjMKMQjDmgESAzM3NxiGJiDvxAEosPqKAzCw-4oDOEVAAFgBagVCQVNJQ3IIRUxBMlRZMlMSCggBEAEYASoCQ00YASIECAEQASgCKAMoBDAB) ## Find the cheapest month to fly from Panama City (PTY) to Guayaquil (GYE) ### June is typically the cheapest month to fly From CA $335 - CA $677 per traveller. Flight from Panama City to Guayaquil (PTY - GYE) route information | Origin airport | Tocumen Intl. | | --- | --- | | Destination airport | Jose Joaquin de Olmedo Intl. | | Airlines serving | Copa, avianca | | Roundtrip price | CA $638 | | Distance | 1240 km | | Average flight time | 2 hours 16 mins | ## Tocumen to Guayaquil Flights **The easy way to book your flights from Panama City to Guayaquil**  With Expedia, it’s simple to find and book flights to Guayaquil from Panama City whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Jose Joaquin de Olmedo Intl., too.   Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Panama City to Guayaquil today, tomorrow, or this week.   **Save dollars with cheap flights from Tocumen Intl., PTY to Jose Joaquin de Olmedo Intl., GYE**  Sort your search results by price to find great deals on your flight from Panama City to Guayaquil—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Guayaquil from Panama City currently is just CA $639 rising to CA $731.   Here are more money-saving tips:  - Fly in March when flight prices are normally at their lowest  - Book about a month to 6 weeks before you travel for the best prices to Guayaquil   - Avoid peak season and weekends when flights can cost more - Early morning and late-night flights are sometimes cheaper, so try varying your travel times  - One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free!  **Reasons to choose Expedia for your flight to Guayaquil from Panama City**  Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. 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[Urdesa Hotels](https://www.expedia.ca/Urdesa-Guayaquil-Hotels.0-n553248633981744847-0.Travel-Guide-Filter-Hotels) ### Flights - [Flights to Guayaquil](https://www.expedia.ca/Cheap-Flights-To-Guayaquil.d1414.Travel-Guide-Flights) - [Flights to Guayaquil](https://www.expedia.ca/Cheap-Flights-To-Guayaquil.d6337570.Travel-Guide-Flights) - [Flights from Guayas](https://www.expedia.ca/lp/flights/6239779/flights-from-guayas) - [Flights from Guayaquil](https://www.expedia.ca/lp/flights/6337570/flights-from-guayaquil) ### Packages - [Antonio Neumane Park](https://www.expedia.ca/Antonio-Neumane-Park-Kennedy.d6331057.Vacation-Attraction) - [City Mall](https://www.expedia.ca/City-Mall-Guayaquil.d6214252.Vacation-Attraction) - [Dr. Teodoro Maldonado Carbo Hospital](https://www.expedia.ca/Dr-Teodoro-Maldonado-Carbo-Hospital-Guayaquil.d6331051.Vacation-Attraction) - [Duran Vacations](https://www.expedia.ca/Duran.d6325948.Destination-Travel-Guides) - [Visit Buijo Histórico](https://www.expedia.ca/Guayaquil-Buijo-Historico.dx553248635976385128) - 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