CA $497 Cheap United fights from Des Moines (DSM) to San Diego (SAN)

View CA $497 flight on Tue, Nov 4, 2025Opens in a new window
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United flights from Des Moines to San Diego (DSM→SAN)

Prices were available within the past 7 days and start at CA $497 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Flight from Des Moines to San Diego (DSM - SAN) route information
Origin airport
Des Moines Intl.
Destination airport
San Diego Intl.
Distance
2282 km

Frequently asked questions

How much is a United Airlines flight from Des Moines Intl. Airport (DSM) to San Diego Intl. Airport (SAN)?
Landing cheap one-way United Airlines flights from DSM to SAN from CA $497 on Expedia is simple — just filter by "Price (lowest to highest)." Alternatively, check out our affordable round-trip fares for your next getaway.**These prices were available on Expedia within the past 7 days, for flights departing within the next year. Prices and availability are subject to change. Additional terms apply.
What is the cheapest month to fly from DSM to SAN with United Airlines?
Look for one-way or round-trip flights to San Diego in January or November. You could find a cheap fare with United Airlines during these off-peak months.
Does United Airlines fly nonstop from Des Moines Intl. Airport (DSM) to San Diego Intl. Airport (SAN)?
Fill in your dates, click search and use the "Nonstop" filter on Expedia to find any direct flights from DSM to SAN with United Airlines or other airlines.
What airports does United Airlines fly into in San Diego?
San Diego Intl. Airport (SAN) is the primary San Diego gateway for United Airlines flights from Des Moines Intl. Airport (DSM).
Can I change or cancel my United Airlines flight from Des Moines Intl. Airport (DSM) to San Diego Intl. Airport (SAN)?
Depending on the type of fare you purchased, a fee generally applies if you cancel or change your flight more than 24 hours after it's been confirmed. To find flexible fares, select our "No cancel fee" or "Changes included" filter when you look for flights. To learn more about cancelling or changing your reservation, go to "Trips," select your flight and tick "Manage Booking."
*Available to Expedia members.