Title: CA $306 Cheap Flights from Knoxville (TYS) to San Diego (SAN) - Expedia.ca

  

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# CA $306 Cheap Flights from Knoxville (TYS) to San Diego (SAN)

[View CA $306 flight on Wed, Dec 3, 2025](https://expedia.ca/Flights-Search?trip=oneway&leg1=from:TYS,to:SAN,departure:03/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:306.00&airProductToken=AQppCjMIwYIBEgQ1OTY3GJOWASDimgEo2N3-AjCy3v4COEJAAFgBagVCQVNJQ3IIUVdBWlpOQlgKMgjBggESBDE3NDAY4poBIJJoKKLg_gIw3eL-AjhCQAFYAWoFQkFTSUNyCFFXQVpaTkJYEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw)

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-   [One-way](?flightType=oneway)
-   [Multi-city](?flightType=multicity)

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## Popular airlines from Alcoa - Knoxville Airport (TYS) to San Diego Intl. Airport (SAN)

-   ![Alaska Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AS.svg)
    
    Alaska Airlines
    
    [](https://www.expedia.ca/Flights-Search?leg1=from:tys,to:san,departure:01/11/2025TANYT&leg2=from:san,to:tys,departure:08/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AS"}}])
-   ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg)
    
    Delta
    
    [](https://www.expedia.ca/Flights-Search?leg1=from:tys,to:san,departure:01/11/2025TANYT&leg2=from:san,to:tys,departure:08/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}])
-   ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg)
    
    United
    
    [](https://www.expedia.ca/Flights-Search?leg1=from:tys,to:san,departure:01/11/2025TANYT&leg2=from:san,to:tys,departure:08/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}])
-   ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg)
    
    American Airlines
    
    [](https://www.expedia.ca/Flights-Search?leg1=from:tys,to:san,departure:01/11/2025TANYT&leg2=from:san,to:tys,departure:08/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}])
-   ![Frontier Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_F9.svg)
    
    Frontier Airlines
    
    [](https://www.expedia.ca/Flights-Search?leg1=from:tys,to:san,departure:01/11/2025TANYT&leg2=from:san,to:tys,departure:08/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"F9"}}])
-   ![Southwest Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_WN.svg)
    
    Southwest Airlines
    
    [](https://www.expedia.ca/Flights-Search?leg1=from:tys,to:san,departure:01/11/2025TANYT&leg2=from:san,to:tys,departure:08/11/2025TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"WN"}}])

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## Cheap flights from Knoxville (TYS) to San Diego (SAN)

Prices were available within the past 7 days and start at CA $306 for one-way flights and for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

All deals

One way

Roundtrip

## Find the cheapest month to fly from Knoxville (TYS) to San Diego (SAN)

### January is typically the cheapest month to fly

From CA $269 - CA $909 per traveller.

Flight from Knoxville to San Diego (TYS - SAN) route information

| Origin airport | McGhee Tyson |
| --- | --- |
| Destination airport | San Diego Intl. |
| Distance | 3038 km |

## Alcoa to San Diego Flights

**The easy way to book your flights from Knoxville to San Diego** 

With Expedia, it’s simple to find and book flights to San Diego from Knoxville whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 5 airlines that cover this route. There are nonstop flights to San Diego Intl., too.  

Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Knoxville to San Diego today, tomorrow, or this week.  

**Save dollars with cheap flights from McGhee Tyson, TYS to San Diego Intl., SAN** 

Sort your search results by price to find great deals on your flight from Knoxville to San Diego—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to San Diego from Knoxville currently is just rising to .  

Here are more money-saving tips: 

-   Fly in when flight prices are normally at their lowest 
-   Book about a month to 6 weeks before you travel for the best prices to San Diego  
-   Avoid peak season and weekends when flights can cost more
-   Early morning and late-night flights are sometimes cheaper, so try varying your travel times 
-   One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! 

**Reasons to choose Expedia for your flight to San Diego from Knoxville** 

Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to San Diego with Expedia today.

## Frequently asked questions

### How much is a flight from Knoxville Airport to San Diego Airport?

> If you're travelling from Knoxville Airport to SAN, round-trip flights start from . This figure is based on fares advertised within the last 7 days on Expedia for flights departing within the next year, so don't wait around. Book today and save yourself money and time. Prices and availability are subject to change. Additional terms apply.

### Do I need to pay a cancellation fee if I cancel my flight from McGhee Tyson Airport (TYS) to San Diego Airport?

> The majority of flights can be conveniently cancelled online, but whether or not you are charged a fee varies between airlines. If you do need to cancel your trip, follow the easy instructions in the [Customer Service Portal](https://www.expedia.ca/helpcenter).

### How do I find cheap flights from TYS to SAN that have flexible change policies?

> Many carriers will allow you to move your flight without charging a fee. All you pay is the cost difference between the two flights. When looking for Knoxville Airport to San Diego Intl. Airport (SAN) flights, you'll find a "No change fees" filter for you to pick.

### How many hours is the flight from Knoxville Airport to SAN?

> Lasting around 6 hours and 45 minutes, the flight between Knoxville Airport and San Diego Intl. Airport (SAN) is a good opportunity to do some last-minute planning. How about using the time to work on your itinerary for San Diego?

### How far is the flight from Knoxville Airport to San Diego Intl. Airport (SAN)?

> The flight distance between Knoxville Airport and San Diego Airport is 3,100 kilometres. Bring along a drink, a few snacks and an interesting book to read. Keep yourself entertained and time will zip by.

### Which airlines fly direct from TYS to San Diego Intl. Airport (SAN)?

> If you want to travel straight from McGhee Tyson Airport (TYS) to San Diego Airport, you'll need to book a flight with one or more stops. Unfortunately, there are no airlines that fly directly on this route.

### Are Knoxville Airport to San Diego Intl. Airport (SAN) flight tickets cheaper when they're purchased at the last minute?

> Booking your trip from McGhee Tyson Airport (TYS) to San Diego Airport at the last minute could be your ticket to a great deal. However, it might cost you a whole lot more! If you'd prefer not to take the risk, book well ahead of your departure date. In fact, Expedia has some of the biggest bargains up to a year in advance. If your preferred carrier hasn't released tickets yet, check back frequently as deals are updated on Expedia all the time.

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