
Popular airlines from Alcoa - Knoxville Airport (TYS) to Chicago
- Delta
Delta
- American Airlines
American Airlines
- United
United
- Frontier Airlines
Frontier Airlines
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Cheap flights from Knoxville (TYS) to Chicago (CHI)
Prices were available within the past 7 days and start at CA $308 for one-way flights and CA $440 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.










Find the cheapest month to fly from Knoxville (TYS) to Chicago (CHI)
November is typically the cheapest month to fly
Graph displaying average flight prices per month
Origin airport | McGhee Tyson |
Destination airport | Midway Intl. |
Roundtrip price | CA $440 |
Distance | 735 km |
Alcoa to Illinois Flights
The easy way to book your flights from Knoxville to Chicago
With Expedia, it’s simple to find and book flights to Chicago from Knoxville whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 14 airlines that cover this route. There are nonstop flights to CHI-All Airports, too.
Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Knoxville to Chicago today, tomorrow, or this week.
Save dollars with cheap flights from McGhee Tyson, TYS to CHI-All Airports, CHI
Sort your search results by price to find great deals on your flight from Knoxville to Chicago—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Chicago from Knoxville currently is just CA $440 rising to CA $674.
Here are more money-saving tips:
- Fly in September when flight prices are normally at their lowest
- Book about a month to 6 weeks before you travel for the best prices to Chicago
- Avoid peak season and weekends when flights can cost more
- Early morning and late-night flights are sometimes cheaper, so try varying your travel times
- One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free!
Reasons to choose Expedia for your flight to Chicago from Knoxville
Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Chicago with Expedia today.
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Top Routes from Knoxville
- Knoxville to Ottawa (TYS - YOW)
- Knoxville to Calgary (TYS - YYC)
- Knoxville to Kelowna (TYS - YLW)
- Knoxville to Detroit (TYS - DTW)
- Knoxville to Spokane (TYS - GEG)
- Knoxville to Winnipeg (TYS - YWG)
- Knoxville to Halifax (TYS - YHZ)
- Knoxville to Victoria (TYS - YYJ)
- Knoxville to Montreal (TYS - YUL)
- Knoxville to Ahmedabad (TYS - AMD)
- Knoxville to Toronto (TYS - YYZ)
Top Routes to Chicago
- Ottawa to Chicago (YOW - CHI)
- Calgary to Chicago (YYC - CHI)
- Buffalo to Chicago (BUF - CHI)
- Vancouver to Chicago (YVR - CHI)
- Edmonton to Chicago (YEA - CHI)
- Toronto to Chicago (YTO - CHI)
- Detroit to Chicago (DTT - CHI)
- Winnipeg to Chicago (YWG - CHI)
- Halifax to Chicago (YHZ - CHI)
- Montreal to Chicago (YMQ - CHI)
Top Routes from Knoxville
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Chicago
Main Airports for Flights
- Tri-Cities Regional Airport (TRI)
- Greenville-Spartanburg Intl. Airport (GSP)
- Smyrna Airport (MQY)
- Pike County - Hatcher Field Airport (PVL)
- Nashville Intl. Airport (BNA)
- Hartsfield-Jackson Atlanta Intl. Airport (ATL)
- Blue Grass Airport (LEX)
- Charlotte-Douglas Intl. Airport (CLT)
- Huntsville Intl. Airport (HSV)
- Concord Regional Airport (USA)
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