Title: CA $460 Cheap Flights from Des Moines (DSM) to Greenville (GSP) - Expedia.ca ![Greenville featuring a city, a bridge and a river or creek](https://images.trvl-media.com/place/1388/2f1c4846-4013-4641-a8dd-db2da5ca5774.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Visit Greenville, South Carolina ![](https://images.trvl-media.com/place/1388/2f1c4846-4013-4641-a8dd-db2da5ca5774.jpg?impolicy=fcrop&w=1200&h=500&q=medium) # CA $460 Cheap Flights from Des Moines (DSM) to Greenville (GSP) [View CA $460 flight on Mon, Dec 29, 2025](https://expedia.ca/Flights-Search?trip=oneway&leg1=from:DSM,to:GSP,departure:29/12/2025TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:459.10&airProductToken=AQpkCjAIwYIBEgQ1NTE0GMNkIK4cKLiFgQMwnIaBAzhMQABYAWoETUFJTnIITFVBSVpOTjEKMAjBggESBDQxNTQYrhwgxnwo5IaBAzDeh4EDOExAAVgBagRNQUlOcghMVUFJWk5OMRIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs) - [Roundtrip](?flightType=roundtrip) - [One-way](?flightType=oneway) - [Multi-city](?flightType=multicity) ### Travellers Adults ChildrenAges 2 to 17 InfantsYounger than 2 EconomyPremium economyBusiness classFirst class Leaving from Going to Departing Returning Add a place to stay Add a car Direct flights only ## Popular airlines from Des Moines International Airport (DSM) to Greenville-Spartanburg Intl. Airport (GSP) - ![American Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_AA.svg) American Airlines [](https://www.expedia.ca/Flights-Search?leg1=from:DSM,to:GSP,departure:30/12/2025TANYT&leg2=from:GSP,to:DSM,departure:06/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"AA"}}]) - ![Delta](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_DL.svg) Delta [](https://www.expedia.ca/Flights-Search?leg1=from:DSM,to:GSP,departure:30/12/2025TANYT&leg2=from:GSP,to:DSM,departure:06/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"DL"}}]) - ![United](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_UA.svg) United [](https://www.expedia.ca/Flights-Search?leg1=from:DSM,to:GSP,departure:30/12/2025TANYT&leg2=from:GSP,to:DSM,departure:06/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"UA"}}]) - ![Southwest Airlines](https://forever.travel-assets.com/flex/flexmanager/images/2024/09/23/landing_airline_sq_logo_WN.svg) Southwest Airlines [](https://www.expedia.ca/Flights-Search?leg1=from:DSM,to:GSP,departure:30/12/2025TANYT&leg2=from:GSP,to:DSM,departure:06/01/2026TANYT&trip=roundtrip&passengers=adults:1,children:0,infantinlap:N&mode=search&pageId=0&filters=[{"preferredAirlineFilterValue":{"carrierCode":"WN"}}]) - ![notification illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__notification.svg) ### Be in the know Get alerts if flight prices drop or rise\* - ![deals illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Book smarter Save up to 30% on select hotels after you book a flight\* - ![trophy illustration](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__trophy.svg) ### Earn twice Earn your airline miles on top of our rewards [Sign in](https://www.expedia.ca/login) ## Cheap flights from Des Moines (DSM) to Greenville (GSP) Prices were available within the past 7 days and start at CA $460 for one-way flights and CA $829 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply. All deals One way Roundtrip ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Dec 29 - Fri, Jan 2 DSM Des Moines GSP Greenville CA $829 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DSM,to:GSP,departure:29/12/2025TANYT&leg2=from:GSP,to:DSM,departure:02/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:829.00&airProductToken=AQpkCjAIwYIBEgQ1NTE0GMNkIK4cKLiFgQMwnIaBAzhMQABYAWoETUFJTnIITFVBSVpOTjEKMAjBggESBDQxNTQYrhwgxnwo5IaBAzDeh4EDOExAAVgBagRNQUlOcghMVUFJWk5OMQpmCjEIwYIBEgQxODAwGMZ8IKOxASiUrYEDMMKugQM4R0AAWAFqBE1BSU5yCEdVQUlaTk0xCjEIwYIBEgQzMTkxGKOxASDDZCj2roEDMPGvgQM4R0ABWAFqBE1BSU5yCEdVQUlaTk0xEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Dec 29 - Fri, Jan 2 DSM Des Moines GSP Greenville CA $847 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DSM,to:GSP,departure:29/12/2025TANYT&leg2=from:GSP,to:DSM,departure:02/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:846.20&airProductToken=AQpkCjAIwYIBEgQ1NTE0GMNkIK4cKLiFgQMwnIaBAzhMQABYAWoETUFJTnIITFVBSVpOTjEKMAjBggESBDQxNTQYrhwgxnwo5IaBAzDeh4EDOExAAVgBagRNQUlOcghMVUFJWk5OMQpkCjAIwYIBEgQzOTE4GMZ8IK4cKN-vgQMw4rCBAzhWQABYAWoETUFJTnIIVlVBSVpOTjEKMAjBggESBDQxMDMYrhwgw2QokbGBAzDlsYEDOFZAAVgBagRNQUlOcghWVUFJWk5OMRIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Dec 29 - Fri, Jan 2 DSM Des Moines GSP Greenville CA $920 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DSM,to:GSP,departure:29/12/2025TANYT&leg2=from:GSP,to:DSM,departure:02/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:919.30&airProductToken=AQpkCjAIwYIBEgQ1NTE0GMNkIK4cKLiFgQMwnIaBAzhMQABYAWoETUFJTnIITFVBSVpOTjEKMAjBggESBDQxNTQYrhwgxnwo5IaBAzDeh4EDOExAAVgBagRNQUlOcghMVUFJWk5OMQpmCjEIwYIBEgQ2MDQ1GMZ8IOKaASj4soEDMMKzgQM4TEAAWAFqBE1BSU5yCExVQUlaTk4xCjEIwYIBEgQ1NDM4GOKaASDDZCiCtYEDMK22gQM4TEABWAFqBE1BSU5yCExVQUlaTk4xEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Dec 29 - Fri, Jan 2 DSM Des Moines GSP Greenville CA $924 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DSM,to:GSP,departure:29/12/2025TANYT&leg2=from:GSP,to:DSM,departure:02/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:923.60&airProductToken=AQpmCjEIwYIBEgQxOTg1GMNkIOKaASi3hIEDMMaFgQM4TUAAWAFqBE1BSU5yCE03QUlaTk4xCjEIwYIBEgQ1MjcyGOKaASDGfCiAhoEDMLiGgQM4TUABWAFqBE1BSU5yCE03QUlaTk4xCmYKMQjBggESBDE4MDAYxnwgo7EBKJStgQMwwq6BAzhHQABYAWoETUFJTnIIR1VBSVpOTTEKMQjBggESBDMxOTEYo7EBIMNkKPaugQMw8a-BAzhHQAFYAWoETUFJTnIIR1VBSVpOTTESCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Dec 29 - Fri, Jan 2 DSM Des Moines GSP Greenville CA $940 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DSM,to:GSP,departure:29/12/2025TANYT&leg2=from:GSP,to:DSM,departure:02/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:939.80&airProductToken=AQpmCjEIwYIBEgQxOTg1GMNkIOKaASi3hIEDMMaFgQM4TUAAWAFqBE1BSU5yCE03QUlaTk4xCjEIwYIBEgQ1MjcyGOKaASDGfCiAhoEDMLiGgQM4TUABWAFqBE1BSU5yCE03QUlaTk4xCmQKMAjBggESBDM5MTgYxnwgrhwo36-BAzDisIEDOFZAAFgBagRNQUlOcghWVUFJWk5OMQowCMGCARIENDEwMxiuHCDDZCiRsYEDMOWxgQM4VkABWAFqBE1BSU5yCFZVQUlaTk4xEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Mon, Dec 29 - Fri, Jan 2 DSM Des Moines GSP Greenville CA $949 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DSM,to:GSP,departure:29/12/2025TANYT&leg2=from:GSP,to:DSM,departure:02/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:948.91&airProductToken=AQpuCjUIxJgBEgQxNzA0GMNkIOBcKJODgQMwl4SBAzhLQABYAWoJTUFJTkNMQVNDcghLQVVHQTBNUQo1CMSYARIEMzAwNxjgXCDGfCjzhYEDMK2GgQM4S0ABWAFqCU1BSU5DTEFTQ3IIS0FVR0EwTVESCggBEAEYASoCREwYASIECAEQASgCKAMoBDAB) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Dec 29 - Fri, Jan 2 DSM Des Moines GSP Greenville CA $968 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DSM,to:GSP,departure:29/12/2025TANYT&leg2=from:GSP,to:DSM,departure:02/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:967.70&airProductToken=AQpoCjIIwYIBEgQ1NTE0GMNkIK4cKLiFgQMwnIaBAzhMQABYAWoGTUFJTkZMcghMVUFJWlJVMQoyCMGCARIENDE1NBiuHCDGfCjkhoEDMN6HgQM4TEABWAFqBk1BSU5GTHIITFVBSVpSVTEKagozCMGCARIEMTgwMBjGfCCjsQEolK2BAzDCroEDOEdAAFgBagZNQUlORkxyCEdVQUlaUlUxCjMIwYIBEgQzMTkxGKOxASDDZCj2roEDMPGvgQM4R0ABWAFqBk1BSU5GTHIIR1VBSVpSVTESCggBEAEYASoCQUEYASIECAEQASgCKAMoBDAL) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Dec 29 - Fri, Jan 2 DSM Des Moines GSP Greenville CA $975 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DSM,to:GSP,departure:29/12/2025TANYT&leg2=from:GSP,to:DSM,departure:02/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:974.95&airProductToken=AQpkCjAIwYIBEgQ1NTE0GMNkIK4cKLiFgQMwnIaBAzhMQABYAWoETUFJTnIITFVBSVpOTjEKMAjBggESBDQxNTQYrhwgxnwo5IaBAzDeh4EDOExAAVgBagRNQUlOcghMVUFJWk5OMRIKCAEQARgBKgJBQRgBIgQIARABKAIoAygEMAs) ![American Airlines](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/AA.gif) Mon, Dec 29 - Fri, Jan 2 DSM Des Moines GSP Greenville CA $984 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DSM,to:GSP,departure:29/12/2025TANYT&leg2=from:GSP,to:DSM,departure:02/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:983.80&airProductToken=AQpoCjIIwYIBEgQ1NTE0GMNkIK4cKLiFgQMwnIaBAzhMQABYAWoGTUFJTkZMcghMVUFJWlJVMQoyCMGCARIENDE1NBiuHCDGfCjkhoEDMN6HgQM4TEABWAFqBk1BSU5GTHIITFVBSVpSVTEKaAoyCMGCARIEMzkxOBjGfCCuHCjfr4EDMOKwgQM4VkAAWAFqBk1BSU5GTHIIVlVBSVpSVTEKMgjBggESBDQxMDMYrhwgw2QokbGBAzDlsYEDOFZAAVgBagZNQUlORkxyCFZVQUlaUlUxEgoIARABGAEqAkFBGAEiBAgBEAEoAigDKAQwCw) ![Delta](//images.trvl-media.com/media/content/expus/graphics/static_content/fusion/v0.1b/images/airlines/DL.gif) Mon, Dec 29 - Fri, Jan 2 DSM Des Moines GSP Greenville CA $998 Roundtrip found 1 day ago [](https://expedia.ca/Flights-Search?trip=roundtrip&leg1=from:DSM,to:GSP,departure:29/12/2025TANYT&leg2=from:GSP,to:DSM,departure:02/01/2026TANYT&passengers=children:0,adults:1,seniors:0,infantinlap:N&mode=search&options=sortby:price&paandi=true&flp=mdl:flights-flex-module,price:997.76&airProductToken=AQpuCjUIxJgBEgQxNzA0GMNkIOBcKJODgQMwl4SBAzhLQABYAWoJTUFJTkNMQVNDcghLQVVHQTBNUQo1CMSYARIEMzAwNxjgXCDGfCjzhYEDMK2GgQM4S0ABWAFqCU1BSU5DTEFTQ3IIS0FVR0EwTVESCggBEAEYASoCREwYASIECAEQASgCKAMoBDAB) ## Find the cheapest month to fly from Des Moines (DSM) to Greenville (GSP) ### August is typically the cheapest month to fly From CA $244 - CA $737 per traveller. __Flight from Des Moines to Greenville (DSM - GSP) route information__ | Origin airport | Des Moines Intl. | | ------------------- | ---------------------------- | | Destination airport | Greenville-Spartanburg Intl. | | Roundtrip price | CA $829 | | Distance | 1233 km | ## Des Moines to Greer Flights **The easy way to book your flights from Des Moines to Greenville** With Expedia, it’s simple to find and book flights to Greenville from Des Moines whether you’re traveling for business or pleasure. Enter your travel dates, hit search, and choose your flight from 20 airlines that cover this route. There are nonstop flights to Greenville-Spartanburg Intl., too. Choose your preferred carrier and cabin class with the advanced search tool and select your ideal departure time. Then, if you want, you can see just nonstop or refundable flights. And if you’re traveling last minute, just enter the date to check out flights from Des Moines to Greenville today, tomorrow, or this week. **Save dollars with cheap flights from Des Moines Intl., DSM to Greenville-Spartanburg Intl., GSP** Sort your search results by price to find great deals on your flight from Des Moines to Greenville—you get all your cheapest options first. Grab yourself a bargain now—the lowest price on flights to Greenville from Des Moines currently is just CA $829 rising to CA $998\. Here are more money-saving tips: - Fly in December when flight prices are normally at their lowest - Book about a month to 6 weeks before you travel for the best prices to Greenville - Avoid peak season and weekends when flights can cost more - Early morning and late-night flights are sometimes cheaper, so try varying your travel times - One surefire way to save money on your flight is to book your flight and hotel together with Expedia. Sometimes, the savings are so large that the flight is basically free! **Reasons to choose Expedia for your flight to Greenville from Des Moines** Whatever your destination, budget, or reason to travel, in just one quick search, you can choose from loads of flights, airlines, and cabin classes. The filters make it quick and easy to find your ideal flights, and if you choose one of the flexible options, you won’t be charged to change your flight. So book your flight to Greenville with Expedia today. ## Frequently asked questions ### How much is a flight from DSM to GSP? ### Do I need to pay a cancellation fee if I cancel my flight from Des Moines Intl. Airport to GSP? ### How do I find cheap flights from DSM to Greenville-Spartanburg Intl. Airport (GSP) that have flexible change policies? ### How many hours is the flight from Des Moines Intl. Airport to Roger Milliken Field? ### How far is the flight from Des Moines Intl. Airport to Roger Milliken Field? ### Which airlines fly direct from Des Moines Intl. Airport to Roger Milliken Field? ### Are Des Moines Intl. Airport (DSM) to Greenville-Spartanburg Intl. Airport (GSP) flight tickets cheaper when they're purchased at the last minute? \*Available to Expedia members.